Journal Information
Vol. 111. Issue 4.
Pages 335-336 (May 2020)
Vol. 111. Issue 4.
Pages 335-336 (May 2020)
Case and Research Letters
DOI: 10.1016/j.adengl.2020.04.002
Open Access
Ultrasound-Guided Fine-Needle Aspiration Biopsy and Core Needle Biopsy of Lymph Node and Subcutaneous Metastases From Lung Adenocarcinoma
PAAF y BAG ecoguiadas en metástasis ganglionar y subcutánea de adenocarcinoma de pulmón
Visits
...
D. Vidala,
Corresponding author
david.vidal@sanitatintegral.org

Corresponding author.
, M. Pujolb
a Servicio de Dermatología, Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, Spain
b Servicio de Anatomía Patológica, Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, Spain
Article information
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Full Text
To the Editor:

A 55-year-old female smoker was seen for 3 subcutaneous nodules that had appeared during the preceding month. The patient had a history of colon cancer (6 years earlier) but was cancer-free at the time of the consultation. Physical examination revealed 3 firm nodules of 1cm in diameter located beneath healthy-looking skin on the upper chest, rib cage, and armpit on the right side of the body (Fig. 1). Doppler ultrasound revealed 3 ovoid hypoechoic lesions in the subcutaneous tissue that lacked posterior reinforcement, exhibited internal vascularization, and were compatible with 2 subcutaneous metastases and 1 lymph node metastasis. After providing written informed consent, the patient underwent fine-needle aspiration (FNA) of the axillary adenopathy with a 21-G needle and core-needle biopsy (CNB) of the lesion on the upper chest with an 18-G needle. The procedures were performed under local anesthesia with ultrasound guidance in the operating room of the dermatology service on the same day as the consultation, with no complications. FNA cytology was positive for malignant cells (Fig. 2). Histology of the CNB was diagnostic of adenocarcinoma metastasis (Fig. 3) and the immunohistochemistry profile (CK7+, TTF-1+, CK20, CDX2) was compatible with a pulmonary origin. Computed tomography revealed findings compatible with lung cancer and the patient was referred to the oncology service for further studies and treatment.

Figure 1.

Lymph node metastasis in the right armpit.

(0.06MB).
Figure 2.

Malignant epithelial cells. Fine-needle aspiration smear (Giemsa staining).

(0.07MB).
Figure 3.

Metastatic adenocarcinoma of the lung. Core-needle biopsy obtained using an 18-G needle (hematoxylin-eosin staining).

(0.12MB).

In cases involving subcutaneous nodules with suspected malignancy the usual practice is to perform an incisional biopsy with a scalpel. Because our patient had 3 lesions, we opted to perform ultrasound-guided FNA and CNB in parallel in order to examine 2 lesions with minimal morbidity. FNA can be performed rapidly and causes minimal pain, and the corresponding pathology report can be rapidly obtained. In some cases, the small sample volume obtained by FNA can complicate the job of the pathologist and can give rise to false negatives. CNB is a better diagnostic technique than FNA as it yields one or more cylinders of histological tissue, from which multiple sections can be obtained and stained.1 Ultrasound-guided FNA and CNB are routinely performed by radiologists,2 but can also be performed by other well-trained ultrasound specialists (e.g. endocrinologists).3 Our dermatology service has had an ultrasound scanner available for consultations for the past 5 years, and we regularly carry out ultrasound-guided procedures. Consequently, our patient was able to benefit from these diagnostic techniques on the day of her consultation. In conclusion, this case illustrates the value of knowledge and experience in performing ultrasound-guided FNA and CNB, which can help dermatologists to rapidly diagnose subcutaneous metastases.

Conflicts of Interest

The authors declare that they have no conflicts of interest.

References
[1]
I. Balasubramanian, C.A. Fleming, M.A. Corrigan, H.P. Redmond, M.J. Kerin, A.J. Lowery.
Meta-analysis of the diagnostic accuracy of ultrasound-guided fine-needle aspiration and core needle biopsy in diagnosing axillary lymph node metastasis.
Br J Surg, 105 (2018), pp. 1244-1253
[2]
M. Soudack, A. Nachtigal, E. Vladovski, O. Brook, D. Gaitini.
Sonographically guided percutaneous needle biopsy of soft tissue masses with histopathologic correlation.
J Ultrasound Med, 25 (2006), pp. 1271-1277
[3]
S. Tofé Povedano, I. Argüelles Jiménez, H. García Fernández, J. Quevedo Juanals, S. Díaz Medina, G. Serra Soler, et al.
Incorporación de la ecografía y la punción de tiroides a la actividad de endocrinología en una consulta de alta resolución.
Endocrinol Nutr, 57 (2010), pp. 43-48

Please cite this article as: Vidal D, Pujol M. PAAF y BAG ecoguiadas en metástasis ganglionar y subcutánea de adenocarcinoma de pulmón. Actas Dermosifiliogr. 2020;111:335–336.

Copyright © 2019. AEDV
Idiomas
Actas Dermo-Sifiliográficas (English Edition)

Subscribe to our newsletter

Article options
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
  • Additional material
Tools
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1273])
Supplemental materials
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

es en
Política de cookies Cookies policy
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.