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Vol. 110. Issue 6.
Pages 490-493 (July - August 2019)
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Vol. 110. Issue 6.
Pages 490-493 (July - August 2019)
Brief Comunication
DOI: 10.1016/j.adengl.2018.01.004
Generalized Lichen Planus Treated With Narrowband UV-B Phototherapy: Results From 10 Patients and a Review of the Literature
Liquen plano generalizado tratado con ultravioleta B de banda estrecha: resultados en 10 pacientes y revisión de la literatura
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M. Fernández-Guarino
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montsefdez@msn.com

Corresponding author.
, S. Aboín, L. Barchino, C. Arsuaga, P. Lázaro Ochaita
Servicio de Dermatología, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, España
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Tables (2)
Table 1. Patient Characteristics and Treatment Outcomes
Table 2. Summary of Published Studies on the Treatment of Generalized Lichen Planus with Narrowband Ultraviolet B Phototherapy
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Abstract

Generalized lichen planus (GLP) can be difficult to treat. One alternative for patients who do not respond to common topical and systemic treatments, such as corticosteroids and oral antihistamines, is phototherapy. Narrowband UV-B phototherapy offers several advantages and is currently the main treatment modality. In this study, we present the results corresponding to 10 patients with generalized lichen planus treated with narrowband UV-B phototherapy. We performed a prospective study of adult patients with generalized lichen planus affecting more than 20% of their body surface area. A complete response was observed in 8 patients (80%) and the disease recurred in 2 of these (recurrence rate, 25%). These rates are similar to those reported in the literature reviewed. Narrowband UV-B phototherapy is a widely used alternative to systemic treatments in GLP, but there are very few reports of its results in the literature.

Keywords:
Phototherapy
Narrowband ultraviolet B
Lichen planus
Resumen

El liquen plano en su forma generalizada (LPG) es en ocasiones difícil de tratar. Cuando fallan los tratamientos tópicos y sistémicos más utilizados como corticoides y antihistamínicos orales la fototerapia se plantea como alternativa. En el momento actual y dadas sus ventajas se utiliza con más frecuencia el ultravioleta B de banda estrecha (UVB-BE). En este trabajo presentamos los resultados en 10 pacientes con LPG tratados con UVB-BE. Para ello realizamos un estudio prospectivo en el que se incluyeron pacientes adultos afectados de LPG en más del 20% de su superficie corporal. Se obtuvo respuesta completa en 8 de los pacientes (80%) con una tasa de recidiva del 25% (2/8). Estos resultados son similares a la literatura revisada. La fototerapia con UVB-BE es ampliamente utilizada como alternativa a los tratamientos sistémicos en el LPG, sin embargo, existen pocos estudios publicados en la literatura sobre sus resultados.

Palabras clave:
Fototerapia
Ultravioleta B de banda estrecha
Liquen plano

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