Introduction: Stretch marks are common lesions that affect areas under stress, especially common in pregnant women and adolescents. Despite its prevalence, its treatment and prevention are a challenge in Dermatology.
Material and Methods: Systematic review of the literature published in PubMed and LILACS (1976-2024). The articles were classified according to their scientific evidence (level 1, randomized controlled studies; level 5, clinical cases).
Results: A total of 69 articles were evaluated: 20 on topical treatments, 35 on lasers and energy devices, and 14 on other therapies. Tretinoin at 0.1% and glycolic acid at different concentrations demonstrated clinical improvement, especially in recent stretch marks. Ablative and non-ablative lasers and radiofrequency with microneedles presented good results. Other treatments, such as PRP, are useful in combination.
Conclusions: Current evidence does not allow defining a single treatment; some works are of low quality and with small samples. The combination of treatments helps to improve results.


