array:23 [
  "pii" => "S1578219010706004"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(10)70600-4"
  "estado" => "S300"
  "fechaPublicacion" => "2010-03-01"
  "aid" => "70600"
  "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
  "copyrightAnyo" => "2010"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Actas Dermosifiliogr. 2010;101:143-50"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1968
    "formatos" => array:3 [
      "EPUB" => 39
      "HTML" => 1171
      "PDF" => 758
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1578219010706016"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(10)70601-6"
    "estado" => "S300"
    "fechaPublicacion" => "2010-03-01"
    "aid" => "70601"
    "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2010;101:151-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2032
      "formatos" => array:3 [
        "EPUB" => 44
        "HTML" => 1307
        "PDF" => 681
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Production of Interleukin 8 by Circulating CLA<span class="elsevierStyleSup">&#43;</span> T Cells With Skin Tropism in Patients With Psoriasis and in Healthy Controls"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "151"
          "paginaFinal" => "155"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Producci&#243;n preferente de IL-8 por linfocitos T CLA<span class="elsevierStyleSup">&#43;</span> circulantes con tropismo cut&#225;neo en pacientes con psoriasis y en sujetos sanos"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46; Ferran, A&#46;B&#46; Galv&#225;n, A&#46; Gim&#233;nez-Arnau, R&#46;M&#46; Pujol, L&#46;F&#46; Santamar&#237;a-Babia"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Ferran"
            ]
            1 => array:2 [
              "nombre" => "A&#46;B&#46;"
              "apellidos" => "Galv&#225;n"
            ]
            2 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Gim&#233;nez-Arnau"
            ]
            3 => array:2 [
              "nombre" => "R&#46;M&#46;"
              "apellidos" => "Pujol"
            ]
            4 => array:2 [
              "nombre" => "L&#46;F&#46;"
              "apellidos" => "Santamar&#237;a-Babia"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010706016?idApp=UINPBA000044"
    "url" => "/15782190/0000010100000002/v1_201304241515/S1578219010706016/v1_201304241515/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219010705990"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(10)70599-0"
    "estado" => "S300"
    "fechaPublicacion" => "2010-03-01"
    "aid" => "70599"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2010;101:129-42"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 3289
      "formatos" => array:3 [
        "EPUB" => 39
        "HTML" => 1705
        "PDF" => 1545
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Consensus Statement</span>"
      "titulo" => "Initial Evaluation&#44; Diagnosis&#44; Staging&#44; Treatment&#44; and Follow-up of Patients with Primary Cutaneous Malignant Melanoma&#46; Consensus Statement of the Network of Catalan and Balearic Melanoma Centers"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "129"
          "paginaFinal" => "142"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Valoraci&#243;n inicial&#44; diagn&#243;stico&#44; estadificaci&#243;n&#44; tratamiento y seguimiento de los pacientes con melanoma maligno primario de la piel&#46; Documento de consenso de la &#8220;Xarxa de Centres de Melanoma de Catalunya i Balears&#8221;"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Mangas, C&#46; Paradelo, S&#46; Puig, F&#46; Gallardo, J&#46; Marcoval, A&#46; Azon, R&#46; Bartralot, S&#46; Bel, X&#46; Bigat&#224;, N&#46; Curc&#243;, J&#46; Dalmau, L&#46;J&#46; del Pozo, C&#46; Ferr&#225;ndiz, M&#46; Formig&#243;n, A&#46; Gonz&#225;lez, M&#46; Just, A&#46; Llambrich, E&#46; Llistosella, J&#46; Malvehy, R&#46;M&#46; Mart&#237;, M&#46;E&#46; Nogu&#233;s, R&#46; Pedragosa, V&#46; Rocamora, M&#46; S&#224;bat, M&#46; Salleras"
          "autores" => array:25 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Mangas"
            ]
            1 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Paradelo"
            ]
            2 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Puig"
            ]
            3 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Gallardo"
            ]
            4 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Marcoval"
            ]
            5 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Azon"
            ]
            6 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Bartralot"
            ]
            7 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Bel"
            ]
            8 => array:2 [
              "nombre" => "X&#46;"
              "apellidos" => "Bigat&#224;"
            ]
            9 => array:2 [
              "nombre" => "N&#46;"
              "apellidos" => "Curc&#243;"
            ]
            10 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Dalmau"
            ]
            11 => array:2 [
              "nombre" => "L&#46;J&#46;"
              "apellidos" => "del Pozo"
            ]
            12 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Ferr&#225;ndiz"
            ]
            13 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Formig&#243;n"
            ]
            14 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Gonz&#225;lez"
            ]
            15 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Just"
            ]
            16 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Llambrich"
            ]
            17 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Llistosella"
            ]
            18 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Malvehy"
            ]
            19 => array:2 [
              "nombre" => "R&#46;M&#46;"
              "apellidos" => "Mart&#237;"
            ]
            20 => array:2 [
              "nombre" => "M&#46;E&#46;"
              "apellidos" => "Nogu&#233;s"
            ]
            21 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Pedragosa"
            ]
            22 => array:2 [
              "nombre" => "V&#46;"
              "apellidos" => "Rocamora"
            ]
            23 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "S&#224;bat"
            ]
            24 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Salleras"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010705990?idApp=UINPBA000044"
    "url" => "/15782190/0000010100000002/v1_201304241515/S1578219010705990/v1_201304241515/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
    "titulo" => "Attitude of the Adult Patient With Atopic Dermatitis to the Disease and Its Treatment&#58; The ACTIDA Study"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "143"
        "paginaFinal" => "150"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "I&#46; Betlloch, R&#46; Izu, M&#46; Lleonart, M&#46; Ferrer, J&#46; Ferrando"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "I&#46;"
            "apellidos" => "Betlloch"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Izu"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Lleonart"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          3 => array:4 [
            "nombre" => "M&#46;"
            "apellidos" => "Ferrer"
            "email" => array:1 [
              0 => "mirleferrer&#64;adknoma&#46;com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff4"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Ferrando"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff5"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital General de Alicante&#44; Alicante&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital de Basurto&#44; Bilbao&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Departamento M&#233;dico&#44; Novartis Farmac&#233;utica S&#46;A&#46;&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
          3 => array:3 [
            "entidad" => "Adknoma Health Research S&#46;L&#46;&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff4"
          ]
          4 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nic de Barcelona&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">e</span>"
            "identificador" => "aff5"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Actitud del paciente adulto con dermatitis at&#243;pica frente a su patolog&#237;a y tratamiento&#46; Estudio ACTIDA"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2009-04-06"
    "fechaAceptado" => "2009-07-28"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec84693"
          "palabras" => array:3 [
            0 => "Atopic dermatitis"
            1 => "Treatment"
            2 => "Patient attitude"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84692"
          "palabras" => array:3 [
            0 => "Dermatitis at&#243;pica"
            1 => "Tratamiento"
            2 => "Actitud del paciente"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To determine the attitude of adult patients with atopic dermatitis &#40;AD&#41; to their disease and its treatment&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A multicenter&#44; cross-sectional study was performed in patients with at least 2 outbreaks of AD in the previous year&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Two hundred twenty-seven dermatologists recruited 1441 analyzable patients&#44; the majority women&#44; with a mean of 3&#46;6 outbreaks per year&#46; Most of the patients &#40;97&#46;2&#37;&#41; indicated that they always or sometimes requested medical evaluation of a new outbreak&#46; In the most recent outbreak&#44; 72&#46;2&#37; had used combined therapy&#44; regardless of the severity of the episode&#59; 2-drug combinations were the most common&#46; The majority of dermatologists prescribed combined therapy&#44; most commonly a 2-drug combination for mild or minimal disease&#44; and 3 or more drugs for moderate to very severe outbreaks&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Treatments used by patients for an outbreak of AD are similar to those prescribed by dermatologists in recent outbreaks&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n y objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer la actitud de los pacientes adultos frente a la dermatitis at&#243;pica &#40;DA&#41; y su tratamiento&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio transversal&#44; multic&#233;ntrico&#44; realizado en pacientes con al menos 2 brotes en el &#250;ltimo a&#241;o&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Doscientos veintisiete dermat&#243;logos reclutaron 1&#46;441 pacientes analizables&#44; mayoritariamente mujeres con 3&#44;6 brotes al a&#241;o de media&#46; La mayor&#237;a de los pacientes &#40;97&#44;2&#37;&#41; indic&#243; que solicitaba&#44; al menos ocasionalmente&#44; asesoramiento m&#233;dico ante nuevos brotes&#46; El 72&#44;2&#37; recurri&#243; a la terapia combinada &#40;TC&#41; en el &#250;ltimo brote&#44; independientemente de su intensidad&#44; siendo las combinaciones de 2 f&#225;rmacos &#40;TC2&#41; las m&#225;s utilizadas&#46; Los dermat&#243;logos indicaron mayoritariamente TC&#44; siendo la TC2 m&#225;s frecuente para formas leves y casi sin enfermedad&#44; y la TC de m&#225;s de 2 f&#225;rmacos en brotes moderados a muy graves&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los tratamientos empleados por los pacientes ante un brote de DA son similares a los indicados por los dermat&#243;logos&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:17 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of life in atopic dermatitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46;Y&#46; Finlay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2002"
                        "volumen" => "45"
                        "paginaInicial" => "S64"
                        "paginaFinal" => "S66"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11423879"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atopic dermatitis is associated with a decrement in health-related quality of life"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G&#46; Kiebert"
                            1 => "S&#46;V&#46; Sorensen"
                            2 => "D&#46; Revicki"
                            3 => "S&#46;C&#46; Fagan"
                            4 => "J&#46;J&#46; Doyle"
                            5 => "J&#46; Cohen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2002"
                        "volumen" => "41"
                        "paginaInicial" => "151"
                        "paginaFinal" => "158"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12010340"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atopic dermatitis&#58; understanding the disease and its management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;L&#46; Levy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1185/030079907X242593"
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Med Res Opin"
                        "fecha" => "2007"
                        "volumen" => "23"
                        "paginaInicial" => "3091"
                        "paginaFinal" => "3103"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17971284"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Worldwide variations in the prevalence of symptoms of atopic eczema in the international study of asthma and allergies in childhood"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "I&#46;I&#46; Williams"
                            1 => "C&#46; Robertson"
                            2 => "A&#46; Stewart"
                            3 => "N&#46; A&#239;t-Khaled"
                            4 => "G&#46; Anabwani"
                            5 => "R&#46; Anderson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1999"
                        "volumen" => "103"
                        "paginaInicial" => "125"
                        "paginaFinal" => "138"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9893196"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of atopic dermatitis&#58; recent advances and future predictions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46; Williams"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Probl Dermatol"
                        "fecha" => "1999"
                        "volumen" => "28"
                        "paginaInicial" => "9"
                        "paginaFinal" => "17"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10374045"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of atopic dermatitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46; Williams"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Dermatol"
                        "fecha" => "2000"
                        "volumen" => "25"
                        "paginaInicial" => "522"
                        "paginaFinal" => "529"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11122223"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical aspects&#44; epidemiology and prognosis of atopic dermatitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "B&#46; Wuthrich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S1081-1206(10)62852-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Allergy Asthma Immunol"
                        "fecha" => "1999"
                        "volumen" => "83"
                        "paginaInicial" => "464"
                        "paginaFinal" => "470"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10582732"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atopic dermatitis&#58; A review of diagnosis and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;E&#46; Correale"
                            1 => "C&#46; Walter"
                            2 => "L&#46;N&#46; Murphy"
                            3 => "T&#46;J&#46; Graig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Fam Phys"
                        "fecha" => "1999"
                        "volumen" => "60"
                        "paginaInicial" => "1191"
                        "paginaFinal" => "1198"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manejo de la dermatitis at&#243;pica en Atenci&#243;n Primaria"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; M&#233;ndez-Cabeza"
                            1 => "H&#46; Alache"
                            2 => "E&#46; Cerrada"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Medifam"
                        "fecha" => "2003"
                        "volumen" => "13"
                        "paginaInicial" => "75"
                        "paginaFinal" => "84"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tratamiento de la dermatitis at&#243;pica en la infancia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "E&#46; Baselga"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr"
                        "fecha" => "2003"
                        "volumen" => "94"
                        "paginaInicial" => "345"
                        "paginaFinal" => "355"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patient and physician perspectives vary on atopic dermatitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46;O&#46; McAlister"
                            1 => "S&#46;J&#46; Tofte"
                            2 => "J&#46;J&#46; Doyle"
                            3 => "A&#46; Jackson"
                            4 => "J&#46;M&#46; Hanifin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cutis"
                        "fecha" => "2002"
                        "volumen" => "69"
                        "paginaInicial" => "461"
                        "paginaFinal" => "466"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12078849"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Measuring atopic eczema severity visually"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;R&#46; Charman"
                            1 => "A&#46;J&#46; Venn"
                            2 => "H&#46; Williams"
                            3 => "M&#46; Bigby"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/archderm.141.9.1146"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "2005"
                        "volumen" => "141"
                        "paginaInicial" => "1146"
                        "paginaFinal" => "1151"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16172312"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atopic dermatitis management&#58; comparing the treatment patterns of dermatologists in Japan&#44; USA and UK"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46;D&#46; Baron"
                            1 => "D&#46; Barzilai"
                            2 => "G&#46; Johnston"
                            3 => "M&#46; Kawashima"
                            4 => "M&#46; Takigawa"
                            5 => "H&#46; Nakagawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2002"
                        "volumen" => "147"
                        "paginaInicial" => "710"
                        "paginaFinal" => "715"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12366417"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Safety and efficacy of pimecrolimus &#40;ASM 981&#41; cream 1&#37; in the treatment of mild and moderate atopic dermatitis in children and adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;F&#46; Eichenfield"
                            1 => "A&#46;W&#46; Lucky"
                            2 => "M&#46; Boguniewicz"
                            3 => "R&#46;G&#46;B&#46; Langley"
                            4 => "R&#46; Cherill"
                            5 => "K&#46; Marshall"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2002"
                        "volumen" => "46"
                        "paginaInicial" => "495"
                        "paginaFinal" => "504"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11907497"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "International Consensus Conference on Atopic Dermatitis II &#40;ICCAD II&#42;&#41;&#58; clinical update and current treatment strategies"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "on behalf of the ICCAD Faculty"
                          "etal" => true
                          "autores" => array:8 [
                            0 => "C&#46; Ellis"
                            1 => "T&#46; Luger"
                            2 => "D&#46; Abeck"
                            3 => "R&#46; Allen"
                            4 => "R&#46;A&#46;C&#46; Graham-Brown"
                            5 => "Y&#46; De Prost"
                            6 => "L&#46;F&#46; Einchenfield"
                            7 => "C&#46; Ferr&#225;ndiz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2003"
                        "volumen" => "148"
                        "paginaInicial" => "3"
                        "paginaFinal" => "10"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12694268"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Atopic dermatitis-Treatment Update"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Rudikoff"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "US Dermatol Rev"
                        "fecha" => "2006"
                        "paginaInicial" => "1"
                        "paginaFinal" => "5"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Validation of the Eczema Area and Severity Index for atopic dermatitis in a cohort of 1&#44;550 patients from the pimecrolimus cream 1&#37; randomized controlled trials programme"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46; Barbier"
                            1 => "C&#46; Paul"
                            2 => "T&#46; Luger"
                            3 => "R&#46; Allen"
                            4 => "Y&#46; De Prost"
                            5 => "K&#46; Papp"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2004"
                        "volumen" => "150"
                        "paginaInicial" => "90"
                        "paginaFinal" => "102"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14746621"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010100000002/v1_201304241515/S1578219010706004/v1_201304241515/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6252"
    "tipo" => "SECCION"
    "fr" => array:2 [
      "titulo" => "Original articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "fr"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010100000002/v1_201304241515/S1578219010706004/v1_201304241515/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010706004?idApp=UINPBA000044"
]
Compartir
Información de la revista
Vol. 101. Núm. 2.
Páginas 143-150 (marzo 2010)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Vol. 101. Núm. 2.
Páginas 143-150 (marzo 2010)
Original Article
Acceso a texto completo
Attitude of the Adult Patient With Atopic Dermatitis to the Disease and Its Treatment: The ACTIDA Study
Actitud del paciente adulto con dermatitis atópica frente a su patología y tratamiento. Estudio ACTIDA
Visitas
5502
I. Betllocha, R. Izub, M. Lleonartc, M. Ferrerd,
Autor para correspondencia
mirleferrer@adknoma.com

Corresponding author.
, J. Ferrandoe
a Servicio de Dermatología, Hospital General de Alicante, Alicante, Spain
b Servicio de Dermatología, Hospital de Basurto, Bilbao, Spain
c Departamento Médico, Novartis Farmacéutica S.A., Barcelona, Spain
d Adknoma Health Research S.L., Barcelona, Spain
e Servicio de Dermatología, Hospital Clínic de Barcelona, Barcelona, Spain
Este artículo ha recibido
Información del artículo
Resumen
Bibliografía
Descargar PDF
Estadísticas
Abstract
Objective

To determine the attitude of adult patients with atopic dermatitis (AD) to their disease and its treatment.

Material and methods

A multicenter, cross-sectional study was performed in patients with at least 2 outbreaks of AD in the previous year.

Results

Two hundred twenty-seven dermatologists recruited 1441 analyzable patients, the majority women, with a mean of 3.6 outbreaks per year. Most of the patients (97.2%) indicated that they always or sometimes requested medical evaluation of a new outbreak. In the most recent outbreak, 72.2% had used combined therapy, regardless of the severity of the episode; 2-drug combinations were the most common. The majority of dermatologists prescribed combined therapy, most commonly a 2-drug combination for mild or minimal disease, and 3 or more drugs for moderate to very severe outbreaks.

Conclusions

Treatments used by patients for an outbreak of AD are similar to those prescribed by dermatologists in recent outbreaks.

Keywords:
Atopic dermatitis
Treatment
Patient attitude
Resumen
Introducción y objetivos

Conocer la actitud de los pacientes adultos frente a la dermatitis atópica (DA) y su tratamiento.

Material y métodos

Estudio transversal, multicéntrico, realizado en pacientes con al menos 2 brotes en el último año.

Resultados

Doscientos veintisiete dermatólogos reclutaron 1.441 pacientes analizables, mayoritariamente mujeres con 3,6 brotes al año de media. La mayoría de los pacientes (97,2%) indicó que solicitaba, al menos ocasionalmente, asesoramiento médico ante nuevos brotes. El 72,2% recurrió a la terapia combinada (TC) en el último brote, independientemente de su intensidad, siendo las combinaciones de 2 fármacos (TC2) las más utilizadas. Los dermatólogos indicaron mayoritariamente TC, siendo la TC2 más frecuente para formas leves y casi sin enfermedad, y la TC de más de 2 fármacos en brotes moderados a muy graves.

Conclusiones

Los tratamientos empleados por los pacientes ante un brote de DA son similares a los indicados por los dermatólogos.

Palabras clave:
Dermatitis atópica
Tratamiento
Actitud del paciente
El Texto completo está disponible en PDF
References
[1.]
A.Y. Finlay.
Quality of life in atopic dermatitis.
J Am Acad Dermatol, 45 (2002), pp. S64-S66
[2.]
G. Kiebert, S.V. Sorensen, D. Revicki, S.C. Fagan, J.J. Doyle, J. Cohen, et al.
Atopic dermatitis is associated with a decrement in health-related quality of life.
Int J Dermatol, 41 (2002), pp. 151-158
[3.]
M.L. Levy.
Atopic dermatitis: understanding the disease and its management.
Curr Med Res Opin, 23 (2007), pp. 3091-3103
[4.]
I.I. Williams, C. Robertson, A. Stewart, N. Aït-Khaled, G. Anabwani, R. Anderson, et al.
Worldwide variations in the prevalence of symptoms of atopic eczema in the international study of asthma and allergies in childhood.
J Allergy Clin Immunol, 103 (1999), pp. 125-138
[5.]
H. Williams.
Epidemiology of atopic dermatitis: recent advances and future predictions.
Curr Probl Dermatol, 28 (1999), pp. 9-17
[6.]
H. Williams.
Epidemiology of atopic dermatitis.
Clin Exp Dermatol, 25 (2000), pp. 522-529
[7.]
B. Wuthrich.
Clinical aspects, epidemiology and prognosis of atopic dermatitis.
Ann Allergy Asthma Immunol, 83 (1999), pp. 464-470
[8.]
C.E. Correale, C. Walter, L.N. Murphy, T.J. Graig.
Atopic dermatitis: A review of diagnosis and treatment.
Am Fam Phys, 60 (1999), pp. 1191-1198
[9.]
J. Méndez-Cabeza, H. Alache, E. Cerrada.
Manejo de la dermatitis atópica en Atención Primaria.
Medifam, 13 (2003), pp. 75-84
[10.]
E. Baselga.
Tratamiento de la dermatitis atópica en la infancia.
Actas Dermosifiliogr, 94 (2003), pp. 345-355
[11.]
R.O. McAlister, S.J. Tofte, J.J. Doyle, A. Jackson, J.M. Hanifin.
Patient and physician perspectives vary on atopic dermatitis.
Cutis, 69 (2002), pp. 461-466
[12.]
C.R. Charman, A.J. Venn, H. Williams, M. Bigby.
Measuring atopic eczema severity visually.
Arch Dermatol, 141 (2005), pp. 1146-1151
[13.]
E.D. Baron, D. Barzilai, G. Johnston, M. Kawashima, M. Takigawa, H. Nakagawa, et al.
Atopic dermatitis management: comparing the treatment patterns of dermatologists in Japan, USA and UK.
Br J Dermatol, 147 (2002), pp. 710-715
[14.]
L.F. Eichenfield, A.W. Lucky, M. Boguniewicz, R.G.B. Langley, R. Cherill, K. Marshall, et al.
Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents.
J Am Acad Dermatol, 46 (2002), pp. 495-504
[15.]
C. Ellis, T. Luger, D. Abeck, R. Allen, R.A.C. Graham-Brown, Y. De Prost, L.F. Einchenfield, C. Ferrándiz, on behalf of the ICCAD Faculty, et al.
International Consensus Conference on Atopic Dermatitis II (ICCAD II*): clinical update and current treatment strategies.
Br J Dermatol, 148 (2003), pp. 3-10
[16.]
D. Rudikoff.
Atopic dermatitis-Treatment Update.
US Dermatol Rev, (2006), pp. 1-5
[17.]
N. Barbier, C. Paul, T. Luger, R. Allen, Y. De Prost, K. Papp, et al.
Validation of the Eczema Area and Severity Index for atopic dermatitis in a cohort of 1,550 patients from the pimecrolimus cream 1% randomized controlled trials programme.
Br J Dermatol, 150 (2004), pp. 90-102
Copyright © 2010. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
Descargar PDF
Idiomas
Actas Dermo-Sifiliográficas
Opciones de artículo
Herramientas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?