array:24 [
  "pii" => "S1578219016000664"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2016.02.010"
  "estado" => "S300"
  "fechaPublicacion" => "2016-05-01"
  "aid" => "1307"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2015"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2016;107:349-51"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 734
    "formatos" => array:3 [
      "EPUB" => 38
      "HTML" => 480
      "PDF" => 216
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0001731015005086"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2015.07.018"
      "estado" => "S300"
      "fechaPublicacion" => "2016-05-01"
      "aid" => "1307"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2016;107:349-51"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 300
        "formatos" => array:3 [
          "EPUB" => 3
          "HTML" => 206
          "PDF" => 91
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta cient&#237;fico-cl&#237;nica</span>"
        "titulo" => "Imagen ecogr&#225;fica del hidroadenoma poroide"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "349"
            "paginaFinal" => "351"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Ultrasound Image of Poroid Hidradenoma"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1126
                "Ancho" => 1500
                "Tamanyo" => 172830
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#41; P&#225;pula eritematosa en el muslo derecho sobre var&#237;culas en mujer con insuficiencia venosa cr&#243;nica&#46; B&#41; Se aprecia el componente subcut&#225;neo de la lesi&#243;n&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "C&#46; Mart&#237;nez-Mor&#225;n, R&#46; Khedaoui, B&#46; Echeverr&#237;a-Garc&#237;a, J&#46; Borbujo"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "C&#46;"
                "apellidos" => "Mart&#237;nez-Mor&#225;n"
              ]
              1 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Khedaoui"
              ]
              2 => array:2 [
                "nombre" => "B&#46;"
                "apellidos" => "Echeverr&#237;a-Garc&#237;a"
              ]
              3 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Borbujo"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219016000664"
          "doi" => "10.1016/j.adengl.2016.02.010"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016000664?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015005086?idApp=UINPBA000044"
      "url" => "/00017310/0000010700000004/v1_201604280046/S0001731015005086/v1_201604280046/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219016000676"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2016.02.011"
    "estado" => "S300"
    "fechaPublicacion" => "2016-05-01"
    "aid" => "1309"
    "copyright" => "AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2016;107:352-4"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 557
      "formatos" => array:3 [
        "EPUB" => 40
        "HTML" => 388
        "PDF" => 129
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Pruritic Lesions During Pregnancy&#58; An Unusual Presentation of a Rare Variant of Multibacillary Leprosy"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "352"
          "paginaFinal" => "354"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Lesiones pruriginosas en el embarazo como presentaci&#243;n inusual de una variante poco frecuente de lepra multibacilar"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 730
              "Ancho" => 1700
              "Tamanyo" => 324643
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Nodular dermal infiltrates of histiocytes with foamy cytoplasm masively parasitized by bacilli that were positive on Job-Chaco modified Fite-Faraco stain&#44; and scattered lymphocytes&#46; This dense dermal infiltrate was separated from the epidermis by a band of healthy dermis&#46; A&#44; Hematoxylin and eosin&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;4&#46; B&#44; Job-Chaco modified Fite-Faraco stain&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>4&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A&#46; S&#225;nchez-Orta, M&#46;F&#46; Alb&#237;zuri Prado, T&#46; Gonz&#225;lez Pessolani, E&#46; Sendagorta Cud&#243;s"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "S&#225;nchez-Orta"
            ]
            1 => array:2 [
              "nombre" => "M&#46;F&#46;"
              "apellidos" => "Alb&#237;zuri Prado"
            ]
            2 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Gonz&#225;lez Pessolani"
            ]
            3 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Sendagorta Cud&#243;s"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731015005104"
        "doi" => "10.1016/j.ad.2015.08.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015005104?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016000676?idApp=UINPBA000044"
    "url" => "/15782190/0000010700000004/v1_201604280043/S1578219016000676/v1_201604280043/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219016000652"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2016.02.009"
    "estado" => "S300"
    "fechaPublicacion" => "2016-05-01"
    "aid" => "1300"
    "copyright" => "AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2016;107:347-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 778
      "formatos" => array:3 [
        "EPUB" => 45
        "HTML" => 509
        "PDF" => 224
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Concentric or Targetoid Regrowth in Alopecia Areata"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "347"
          "paginaFinal" => "349"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Crecimiento conc&#233;ntrico en la alopecia areata &#40;patr&#243;n en diana&#41;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 2140
              "Ancho" => 2000
              "Tamanyo" => 738735
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Concentric areas of alopecia and hair regrowth producing a targetoid pattern&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "B&#46; Monteagudo, O&#46; Su&#225;rez-Magdalena, D&#46; Gonz&#225;lez-Vilas, &#211;&#46; Su&#225;rez-Amor"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "B&#46;"
              "apellidos" => "Monteagudo"
            ]
            1 => array:2 [
              "nombre" => "O&#46;"
              "apellidos" => "Su&#225;rez-Magdalena"
            ]
            2 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Gonz&#225;lez-Vilas"
            ]
            3 => array:2 [
              "nombre" => "&#211;&#46;"
              "apellidos" => "Su&#225;rez-Amor"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731015004962"
        "doi" => "10.1016/j.ad.2015.08.009"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015004962?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016000652?idApp=UINPBA000044"
    "url" => "/15782190/0000010700000004/v1_201604280043/S1578219016000652/v1_201604280043/en/main.assets"
  ]
  "en" => array:16 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>"
    "titulo" => "Ultrasound Image of Poroid Hidradenoma"
    "tieneTextoCompleto" => true
    "saludo" => "<span class="elsevierStyleItalic">To the Editor&#58;</span>"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "349"
        "paginaFinal" => "351"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "C&#46; Mart&#237;nez-Mor&#225;n, R&#46; Khedaoui, B&#46; Echeverr&#237;a-Garc&#237;a, J&#46; Borbujo"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "C&#46;"
            "apellidos" => "Mart&#237;nez-Mor&#225;n"
            "email" => array:1 [
              0 => "cmmoran&#64;salud&#46;madrid&#46;org"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Khedaoui"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "B&#46;"
            "apellidos" => "Echeverr&#237;a-Garc&#237;a"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Borbujo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Universitario de Fuenlabrada&#44; Fuenlabrada&#44; Madrid&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Anatom&#237;a Patol&#243;gica&#44; Hospital Universitario de Fuenlabrada&#44; Fuenlabrada&#44; Madrid&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Imagen ecogr&#225;fica del hidroadenoma poroide"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1443
            "Ancho" => 1800
            "Tamanyo" => 524027
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histopathology&#58; A&#44; A solid-cystic lesion in the dermis&#46; Hematoxylin and eosin &#40;H&#38;E&#41;&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>20&#41;&#46; B&#44; Image showing the focal connection with the overlying epidermis&#46; H&#38;E&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>20&#41;&#46; C&#44; Poroid cells with scant cytoplasm&#44; round or oval nuclei&#44; and small nucleoli&#46; H&#38;E&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>400&#46; D&#44; Cuticular cells with abundant eosinophilic cytoplasm lining a duct lumen&#46; H&#38;E&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>400&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We present the case of a 57-year-old woman with allergy to codeine and a history of osteoporosis&#44; systemic hypertension&#44; allergic rhinitis&#44; and anxiety&#46; She was on treatment with metamizole&#44; enalapril plus hydrochlorothiazide&#44; ebastine&#44; and alprazolam&#46; She consulted for a stable&#44; asymptomatic lesion that had arise approximately 4 years earlier on the right thigh and that had never been treated&#46; Physical examination revealed a 7-mm&#8211;diameter&#44; erythematous&#44; desquamating papule with a central blood-stained scab &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41; on the lateral surface of the distal right thigh&#46; Deep to the papule was a lesion of rubbery consistency measuring 15<span class="elsevierStyleHsp" style=""></span>mm in diameter &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">High-frequency skin ultrasound &#40;15<span class="elsevierStyleHsp" style=""></span>MHz&#41; was performed to determine whether this was a single lesion or 2 independent lesions &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>A&#41;&#46; B-mode ultrasound showed a well-defined&#44; hypoechoic lesion in the subcutaneous cellular tissue&#59; the lesion had a cystic appearance with a slightly more echogenic area on its right side&#46; Immediately superficial to this cystic lesion&#44; and in contact with it&#44; was a well-defined&#44; hypoechoic&#44; exophytic dermal lesion&#46; The epidermis was thickened&#46; Doppler examination showed vessels at the periphery of the lesion&#44; but not within it &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>B&#41;&#46; These findings supported the clinical suspicion of a single lesion&#44; and it was excised en bloc&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Histopathology showed a mixed solid-cystic&#44; nodular dermal lesion &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>A&#41; that focally made contact with the epidermis &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>B&#41;&#46; The nodule was formed of poroid cells with round or oval nuclei&#44; small nucleoli&#44; and scant cytoplasm &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>C&#41;&#46; Between the poroid cells were occasional larger cuticular cells that frequently lined ductal lumens &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>D&#41;&#46; There was no evidence of atypia&#44; mitoses&#44; or necrosis&#46; Based on these findings we made a diagnosis of poroid hidradenoma&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Poroid hidradenoma is a variant of eccrine poroma&#44; which belongs to the group of poroid tumors described in 1990 by Abenoza and Ackerman&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Those authors described the 4 histological variants of eccrine poroma&#58; hidroacanthoma simplex&#44; classic poroma&#44; dermal duct tumor&#44; and poroid hidradenoma&#44; which was the tumor in our patient&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">To date&#44; around 50 cases of poroid hidradenoma have been reported&#46; Patient age varies between 13 and 86 years&#44; with a peak in the sixth and seventh decades of life&#44;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">2&#44;3</span></a> and a slight female predominance&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The tumor presents clinically as a solitary lesion&#44; with no preferential anatomic site&#44; though it has not been reported on the palms or soles&#46; Clinical descriptions describe nonspecific cutaneous or subcutaneous lesions&#44; polypoid nodules&#44; or cysts of 1 to 2<span class="elsevierStyleHsp" style=""></span>cm diameter&#46; The lesions are erythematous&#44; reddish&#44; or bluish in color and may be ulcerated&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Histopathology reveals structural elements of hidradenoma &#40;solid-cystic areas&#41;&#44; and cytologic features of poroma &#40;poroid and cuticular cells&#44; the latter cells showing ductal differentiation&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">In the literature reviewed&#44; we have found no reports that describe the skin ultrasound features of poroid hidradenoma or of lesions with a similar appearance&#44; with a cystic component with a more superficial papular component&#46; In our case&#44; ultrasound and histopathology findings were concordant&#58; a cystic lesion connected to the overlying epidermis&#44; suggesting this was a single lesion&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">The prognosis is excellent and no cases of malignant change have been reported&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">As this is a neoplasm that arises in the dermis&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> the recommended treatment is complete radical excision of the lesion&#46; En bloc surgical excision including the overlying epidermis and the surrounding adipose tissue&#44; as was performed in our patient&#44; prevents recurrence&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">The benefit of performing ultrasound in our patient was the correlation between the clinical and histopathological findings&#58; confirmation of the clinical suspicion of a dermal lesion connected to the epidermis and of benign appearance &#40;peripheral vascularization on ultrasound&#41; allowed us to plan en bloc surgical excision without margins&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of Interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Mart&#237;nez-Mor&#225;n C&#44; Khedaoui R&#44; Echeverr&#237;a-Garc&#237;a B&#44; Borbujo J&#46; Imagen ecogr&#225;fica del hidroadenoma poroide&#46; Actas Dermosifiliogr&#46; 2016&#59;107&#58;350&#8211;352&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1126
            "Ancho" => 1500
            "Tamanyo" => 180258
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Erythematous papule overlying varices on the right thigh of a woman with chronic venous insufficiency&#46; B&#44; The subcutaneous component of the lesion can be observed&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 717
            "Ancho" => 1950
            "Tamanyo" => 129222
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; Skin ultrasound shows a well-defined hypoechoic lesion&#46; On the right side of the image there is a more hyperechoic area&#44; which could correspond to the histologic image in Figure<span class="elsevierStyleHsp" style=""></span>3A&#46; The lesion&#44; located in the subcutaneous cellular tissue&#44; had a cystic appearance and measured 11&#46;24<span class="elsevierStyleHsp" style=""></span>mm&#46; It showed posterior acoustic enhancement and oblique lateral shadows&#46; B&#44; Echo Doppler&#46; Blood vessels are visible at the periphery of the lesion&#44; but not within it&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1443
            "Ancho" => 1800
            "Tamanyo" => 524027
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histopathology&#58; A&#44; A solid-cystic lesion in the dermis&#46; Hematoxylin and eosin &#40;H&#38;E&#41;&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>20&#41;&#46; B&#44; Image showing the focal connection with the overlying epidermis&#46; H&#38;E&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>20&#41;&#46; C&#44; Poroid cells with scant cytoplasm&#44; round or oval nuclei&#44; and small nucleoli&#46; H&#38;E&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>400&#46; D&#44; Cuticular cells with abundant eosinophilic cytoplasm lining a duct lumen&#46; H&#38;E&#44; original magnification<span class="elsevierStyleHsp" style=""></span>&#215;<span class="elsevierStyleHsp" style=""></span>400&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Poromas&#46; Neoplasms with eccrine differentiation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Abenoza"
                            1 => "B&#46; Ackerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "fecha" => "1990"
                        "paginaInicial" => "113"
                        "paginaFinal" => "185"
                        "editorial" => "Lea and Febiger"
                        "editorialLocalizacion" => "Philadelphia"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "From hidroacanthoma simplex to poroid hidradenoma&#58; Clinicopathologic and immunohistochemic study of poroid neoplasms and reappraisal of their histogenesis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Battistella"
                            1 => "L&#46; Langbein"
                            2 => "B&#46; Peltre"
                            3 => "B&#46; Cribier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DAD.0b013e3181bc91ff"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Dermatopathol"
                        "fecha" => "2010"
                        "volumen" => "32"
                        "paginaInicial" => "459"
                        "paginaFinal" => "468"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20571345"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Poroid hidradenoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Cho"
                            1 => "J&#46;S&#46; Kim"
                            2 => "J&#46;H&#46; Shin"
                            3 => "J&#46;H&#46; Kim"
                            4 => "H&#46;J&#46; Kim"
                            5 => "K&#46;K&#46; Whang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2001"
                        "volumen" => "40"
                        "paginaInicial" => "62"
                        "paginaFinal" => "64"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11277959"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hidroadenoma poroide"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Monteagudo"
                            1 => "B&#46; Iglesias"
                            2 => "C&#46; de la Torre"
                            3 => "C&#46; Paredes"
                            4 => "M&#46; V&#225;zquez-Blanco"
                            5 => "M&#46; Ginarte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliograf"
                        "fecha" => "2005"
                        "volumen" => "96"
                        "paginaInicial" => "398"
                        "paginaFinal" => "399"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Poroid hidradenoma&#58; A case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Delfino"
                            1 => "V&#46; Toto"
                            2 => "B&#46; Brunetti"
                            3 => "M&#46;P&#46; di Marino"
                            4 => "A&#46; Baldi"
                            5 => "P&#46; Persichetti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "In Vivo"
                        "fecha" => "2007"
                        "volumen" => "21"
                        "paginaInicial" => "905"
                        "paginaFinal" => "907"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18019434"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000010700000004/v1_201604280043/S1578219016000664/v1_201604280043/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6157"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case and Research Letters"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010700000004/v1_201604280043/S1578219016000664/v1_201604280043/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016000664?idApp=UINPBA000044"
]
Share
Journal Information
Vol. 107. Issue 4.
Pages 349-351 (May 2016)
Vol. 107. Issue 4.
Pages 349-351 (May 2016)
Case and Research Letter
Full text access
Ultrasound Image of Poroid Hidradenoma
Imagen ecográfica del hidroadenoma poroide
Visits
5644
C. Martínez-Morána,
Corresponding author
cmmoran@salud.madrid.org

Corresponding author.
, R. Khedaouib, B. Echeverría-Garcíaa, J. Borbujoa
a Servicio de Dermatología, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain
b Servicio de Anatomía Patológica, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain
This item has received
Article information
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Full Text
To the Editor:

We present the case of a 57-year-old woman with allergy to codeine and a history of osteoporosis, systemic hypertension, allergic rhinitis, and anxiety. She was on treatment with metamizole, enalapril plus hydrochlorothiazide, ebastine, and alprazolam. She consulted for a stable, asymptomatic lesion that had arise approximately 4 years earlier on the right thigh and that had never been treated. Physical examination revealed a 7-mm–diameter, erythematous, desquamating papule with a central blood-stained scab (Fig. 1A) on the lateral surface of the distal right thigh. Deep to the papule was a lesion of rubbery consistency measuring 15mm in diameter (Fig. 1B).

Figure 1.

A, Erythematous papule overlying varices on the right thigh of a woman with chronic venous insufficiency. B, The subcutaneous component of the lesion can be observed.

(0.17MB).

High-frequency skin ultrasound (15MHz) was performed to determine whether this was a single lesion or 2 independent lesions (Fig. 2A). B-mode ultrasound showed a well-defined, hypoechoic lesion in the subcutaneous cellular tissue; the lesion had a cystic appearance with a slightly more echogenic area on its right side. Immediately superficial to this cystic lesion, and in contact with it, was a well-defined, hypoechoic, exophytic dermal lesion. The epidermis was thickened. Doppler examination showed vessels at the periphery of the lesion, but not within it (Fig. 2B). These findings supported the clinical suspicion of a single lesion, and it was excised en bloc.

Figure 2.

A, Skin ultrasound shows a well-defined hypoechoic lesion. On the right side of the image there is a more hyperechoic area, which could correspond to the histologic image in Figure3A. The lesion, located in the subcutaneous cellular tissue, had a cystic appearance and measured 11.24mm. It showed posterior acoustic enhancement and oblique lateral shadows. B, Echo Doppler. Blood vessels are visible at the periphery of the lesion, but not within it.

(0.12MB).

Histopathology showed a mixed solid-cystic, nodular dermal lesion (Fig. 3A) that focally made contact with the epidermis (Fig. 3B). The nodule was formed of poroid cells with round or oval nuclei, small nucleoli, and scant cytoplasm (Fig. 3C). Between the poroid cells were occasional larger cuticular cells that frequently lined ductal lumens (Fig. 3D). There was no evidence of atypia, mitoses, or necrosis. Based on these findings we made a diagnosis of poroid hidradenoma.

Figure 3.

Histopathology: A, A solid-cystic lesion in the dermis. Hematoxylin and eosin (H&E), original magnification×20). B, Image showing the focal connection with the overlying epidermis. H&E, original magnification×20). C, Poroid cells with scant cytoplasm, round or oval nuclei, and small nucleoli. H&E, original magnification×400. D, Cuticular cells with abundant eosinophilic cytoplasm lining a duct lumen. H&E, original magnification×400.

(0.5MB).

Poroid hidradenoma is a variant of eccrine poroma, which belongs to the group of poroid tumors described in 1990 by Abenoza and Ackerman.1 Those authors described the 4 histological variants of eccrine poroma: hidroacanthoma simplex, classic poroma, dermal duct tumor, and poroid hidradenoma, which was the tumor in our patient.

To date, around 50 cases of poroid hidradenoma have been reported. Patient age varies between 13 and 86 years, with a peak in the sixth and seventh decades of life,2,3 and a slight female predominance.

The tumor presents clinically as a solitary lesion, with no preferential anatomic site, though it has not been reported on the palms or soles. Clinical descriptions describe nonspecific cutaneous or subcutaneous lesions, polypoid nodules, or cysts of 1 to 2cm diameter. The lesions are erythematous, reddish, or bluish in color and may be ulcerated.2

Histopathology reveals structural elements of hidradenoma (solid-cystic areas), and cytologic features of poroma (poroid and cuticular cells, the latter cells showing ductal differentiation).4

In the literature reviewed, we have found no reports that describe the skin ultrasound features of poroid hidradenoma or of lesions with a similar appearance, with a cystic component with a more superficial papular component. In our case, ultrasound and histopathology findings were concordant: a cystic lesion connected to the overlying epidermis, suggesting this was a single lesion.

The prognosis is excellent and no cases of malignant change have been reported.

As this is a neoplasm that arises in the dermis,5 the recommended treatment is complete radical excision of the lesion. En bloc surgical excision including the overlying epidermis and the surrounding adipose tissue, as was performed in our patient, prevents recurrence.

The benefit of performing ultrasound in our patient was the correlation between the clinical and histopathological findings: confirmation of the clinical suspicion of a dermal lesion connected to the epidermis and of benign appearance (peripheral vascularization on ultrasound) allowed us to plan en bloc surgical excision without margins.

Conflicts of Interest

The authors declare that they have no conflicts of interest.

References
[1]
P. Abenoza, B. Ackerman.
Poromas. Neoplasms with eccrine differentiation.
Lea and Febiger, (1990), pp. 113-185
[2]
M. Battistella, L. Langbein, B. Peltre, B. Cribier.
From hidroacanthoma simplex to poroid hidradenoma: Clinicopathologic and immunohistochemic study of poroid neoplasms and reappraisal of their histogenesis.
Am J Dermatopathol, 32 (2010), pp. 459-468
[3]
S. Cho, J.S. Kim, J.H. Shin, J.H. Kim, H.J. Kim, K.K. Whang, et al.
Poroid hidradenoma.
Int J Dermatol, 40 (2001), pp. 62-64
[4]
B. Monteagudo, B. Iglesias, C. de la Torre, C. Paredes, M. Vázquez-Blanco, M. Ginarte, et al.
Hidroadenoma poroide.
Actas Dermosifiliograf, 96 (2005), pp. 398-399
[5]
S. Delfino, V. Toto, B. Brunetti, M.P. di Marino, A. Baldi, P. Persichetti.
Poroid hidradenoma: A case report.
In Vivo, 21 (2007), pp. 905-907

Please cite this article as: Martínez-Morán C, Khedaoui R, Echeverría-García B, Borbujo J. Imagen ecográfica del hidroadenoma poroide. Actas Dermosifiliogr. 2016;107:350–352.

Copyright © 2015. AEDV
Download PDF
Idiomas
Actas Dermo-Sifiliográficas
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?