Article information
Abstract
Photodynamic therapy (PDT) is approved for the treatment of actinic keratoses, superficial and nodular basal cell carcinomas, and recently, Bowehs disease. In the last decade the advances experienced in the study of the photodynamic reaction have expanded the spectrum of application to other cutaneous diseases, neoplastic as well as inflammatory and infectious ones. The experience in psoriasis, acne, common warts and cutaneous T cell lymphoma starts to be broad and interesting, which permits to define its use in these entities. Photodynamic therapy is also been tested for a great variety of dermatoses with different photosensitizers and light sources with variable results. In this paper we review the treatment of Bowehs disease and other indications different from non melanoma skin cancer with PDT, providing our experience.
Key words:
photodynamic therapy
photosensitizers
non melanoma skin cancer
Resumen
Las indicaciones aprobadas de la terapia fotodinámica (TFD) son las queratosis actínicas, carcinomas basocelulares superficiales y nodulares y recientemente la enfermedad de Bowen. En la última década el estudio de la reacción fotodinámica ha experimentado un avance, ampliándose su espectro de actuación a otras enfermedades cutáneas tanto tumorales como inflamatorias e infecciosas. La experiencia en psoriasis, acné, verrugas vulgares y linfoma cutáneo de células T comienza a ser amplia e interesante, lo que permite definir su uso en estos procesos. Otra gran variedad de dermatosis se está ensayando, con diferentes fotosensibilizantes y fuentes de luz, con resultados variables. En este artículo revisamos el tratamiento con TFD de la enfermedad de Bowen y de otras indicaciones diferentes de cáncer cutáneo no melanoma, añadiendo nuestra experiencia.
Palabras clave:
terapia fotodinámica
fotosensibilizantes
cáncer cutáneo no melanoma
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