Publish in this journal
Journal Information
Vol. 106. Issue 7.
Pages 585 (September 2015)
Vol. 106. Issue 7.
Pages 585 (September 2015)
Images en Dermatology
DOI: 10.1016/j.adengl.2015.06.012
Full text access
Long-Standing Presternal Plaque
Placa preesternal de larga evolución
Visits
...
G. Blasco-Morente
Corresponding author
gonzaloblascomorente@gmail.com

Corresponding author.
, C. Garrido-Colmenero, I. Pérez-López, J. Espelt-Otero
Unidad de Gestión Clínica de Dermatología Médico Quirúrgica y Venereología, Hospital Universitario Virgen de las Nieves, Granada, Spain
Article information
Full Text
Download PDF
Statistics
Figures (1)
Full Text

The patient was a 61-year-old man who had undergone liver transplant for alcoholic cirrhosis 3 years earlier and was on treatment with tacrolimus, 7mg/d, and mycophenolate mofetil, 1.5g/d. He was seen for a 2-year history of skin lesions that had arisen in the presternal region and that produced occasional bleeding and caused discomfort due to friction with clothing. There were no systemic alterations. Physical examination revealed multiple erythematous-violaceous tumors (maximum diameters, 2-3cms) that had coalesced into a large presternal plaque. Some of the tumors had ulcerated and presented a central bloodstained scab (Fig. 1). Histopathology findings on the skin biopsy were compatible with plaque-stage Kaposi sarcoma and immunohistochemistry confirmed the presence of human herpesvirus 8. Blood tests including complete blood count and biochemistry were normal, and serology for human immunodeficiency virus was negative. Thoracic and abdominal computed tomography showed no pathological findings. The diagnosis of Kaposi sarcoma was thus confirmed and radiotherapy treatment was administered, achieving a partial improvement of the clinical manifestations. Kaposi sarcoma is a multifocal systemic tumor associated with human herpesvirus 8 infection. It develops in 0.1% to 5% of transplant recipients. This variant is most common in renal transplant recipients, usually arising in the 2 first years after transplantation. Treatment is symptomatic combined, when possible, with a reduction in immunosuppressant therapy. During follow-up it is important to exclude systemic involvement, which typically affects the digestive tract.

Figure 1.

Presternal plaque of 15x30cm formed by the coalescence of multiple erythematous-violaceous tumors with maximum individual diameters of 2-3cm.

(0.19MB).

Please cite this article as: Blasco-Morente G, Garrido-Colmenero C, Pérez-López I, Espelt-Otero J. Placa preesternal de larga evolución. Actas Dermosifiliogr. 2015;106:585.

Copyright © 2015. Elsevier España, S.L.U. and AEDV
Idiomas
Actas Dermo-Sifiliográficas (English Edition)

Subscribe to our newsletter

Article options
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
    NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
  • Additional material
Tools
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
NOTICE Undefined index: tipo (includes_ws_v2/librerias/html/item.php[1258])
Supplemental materials
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

es en
Política de cookies Cookies policy
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.