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Vol. 110. Issue 6.
Pages 434-447 (July - August 2019)
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Vol. 110. Issue 6.
Pages 434-447 (July - August 2019)
Review
DOI: 10.1016/j.adengl.2019.05.012
Cutaneous Melanoma in the Elderly: Review of a Growing Problem
Melanoma cutáneo en el anciano: revisión de un problema creciente
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N. Iglesias-Penaa, S. Paradelaa, A. Tejera-Vaquerizob,
Corresponding author
antoniotejera@aedv.es

Corresponding author.
, A. Boadac, E. Fonsecaa
a Servicio de Dermatología, Complejo Hospitalario Universitario de A Coruña, A Coruña, España
b Servicio de Dermatología, Instituto Dermatológico GlobalDerm, Palma del Río, Córdoba, España
c Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España
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Tables (3)
Table 1. Studies With Multivariate Analyses That Included Age as a Prognostic Factor in Cutaneous Melanoma.
Table 2. Causes of Delay in Diagnosis of Melanoma in Elderly Patients.
Table 3. Staging and Treatment of Cutaneous Melanoma in Elderly Patients.
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Abstract

Cutaneous melanoma (CM) causes more deaths than any other skin tumor, and incidence and mortality rates have risen in recent years, especially in patients of advanced age. There are differences in the biological behavior of CM tumors in the elderly as well as differential management of the disease, evidently influenced by such factors as limited life expectancy, the high incidence of concomitant conditions in older patients, and issues of quality of life unrelated to CM itself. We review relevant current literature on the epidemiology, etiology, pathogenesis, and immunology of CM as well as research on the clinical features, prevention, and management of these tumors in the elderly.

Keywords:
Melanoma
Elderly
Prognosis
Surgery
Sentinel lymph node
Review
Health services for the aged
Resumen

El melanoma cutáneo (MC) es el tumor cutáneo que más muertes provoca, con un aumento importante de la incidencia y la mortalidad en las últimas décadas, especialmente en el paciente anciano. Existen evidencias del diferente comportamiento biológico, así como de las diferencias en el manejo del MC en este subgrupo de pacientes con respecto al resto de otras franjas de edad, evidentemente condicionadas por unas limitadas expectativas de supervivencia y calidad de vida ajenas al melanoma y una elevada incidencia de comorbilidades. El presente artículo revisa los datos actuales más relevantes de la epidemiología, etiopatogenia e inmunología, clínica, prevención y manejo del MC en el anciano.

Palabras clave:
Melanoma
Anciano
Pronóstico
Cirugía
Ganglio centinela
Revisión
Servicio de salud para el anciano

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