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    "titulo" => "Contact Dermatitis Caused by Acrylates Among 8 Workers in an Elevator Factory"
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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Acrylates are widely used low-molecular-weight substances&#44; initially introduced in industry in the 1930s and subsequently applied also in medicine and the home&#46; One of their main features is the ability to undergo polymerization&#46; The most commonly used acrylic compounds are cyanoacrylates&#44; methacrylates&#44; and acrylates&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To confirm suspicion of occupational disease in a group of workers in an elevator factory&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We studied 8 patients with dermatitis of the hands and finger pads&#46; In their work&#44; the patients came into contact with acrylates&#46; Patch testing was applied with an acrylate panel &#40;BIAL-Aristegui&#44; Bilbao&#44; Spain&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Seven of the patients &#40;87&#46;5&#37;&#41; had a positive result with 1&#37; ethylene glycol dimethacrylate&#46; Positive results were also observed for 2&#37; hydroxyethyl methacrylate &#40;5 patients&#44; 62&#46;5&#37;&#41;&#44; 1&#37; triethylene glycol dimethacrylate &#40;4 patients&#44; 50&#37;&#41;&#44; 10&#37; ethyl methacrylate monomer &#40;3 patients&#44; 37&#46;5&#37;&#41;&#44; 10&#37; methyl methacrylate monomer &#40;2 patients&#44; 25&#37;&#41;&#44; 1&#37; ethyl acrylate &#40;1 patient&#44; 12&#46;5&#37;&#41;&#44; and 0&#46;1&#37; acrylic acid &#40;1 patient&#44; 12&#46;5&#37;&#41;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">We highlight the strong sensitizing capacity of acrylates and the importance of taking all necessary preventive measures in industries where these substances are used&#46; Such measures should include avoidance of contact with the product in cases where sensitization has been confirmed&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Los acrilatos son sustancias qu&#237;micas de bajo peso molecular&#44; con una amplia utilizaci&#243;n en la industria &#40;desde su introducci&#243;n en los a&#241;os treinta&#41;&#44; la medicina y el medio dom&#233;stico&#44; que destacan por sus propiedades de polimerizaci&#243;n&#46; Los compuestos acr&#237;licos m&#225;s utilizados son los cianoacrilatos&#44; los metacrilatos y los acrilatos&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Establecer el diagn&#243;stico de sospecha de enfermedad profesional en un grupo de trabajadores de una f&#225;brica de ascensores&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Se estudian un total de 8 pacientes que presentan cl&#237;nica de dermatitis en las manos&#44; as&#237; como pulpitis en los dedos&#44; y que trabajan en contacto con acrilatos&#46; Se realizaron pruebas epicut&#225;neas con bater&#237;a de acrilatos &#40;BIAL-Aristegui&#44; Bilbao&#44; Espa&#241;a&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">El 87&#44;5&#37; mostr&#243; positividad frente al dimetacrilato de etilenglicol al 1&#37;&#46; Tambi&#233;n mostraron positividad el hidroxietilmetacrilato al 2&#37; &#40;62&#44;5&#37;&#41;&#44; el dimetacrilato de trietilenglicol al 1&#37; &#40;50&#37;&#41;&#44; el mon&#243;mero de metil metacrilato al 10&#37; &#40;25&#37;&#41; y el mon&#243;mero de etil metacrilato al 10&#37; &#40;37&#44;5&#37;&#41;&#44; el acrilato de etilo al 1&#37; &#40;12&#44;5&#37;&#41; y el &#225;cido acr&#237;lico al 0&#44;1&#37; &#40;12&#44;5&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Destacamos el alto poder sensibilizante de los acrilatos y la importancia de extremar las medidas preventivas en las distintas industrias&#44; as&#237; como la evitaci&#243;n del contacto con el producto en los casos de sensibilizaci&#243;n demostrada&#46;</p>"
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Vol. 101. Issue 4.
Pages 336-340 (May 2010)
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Vol. 101. Issue 4.
Pages 336-340 (May 2010)
Original article
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Contact Dermatitis Caused by Acrylates Among 8 Workers in an Elevator Factory
Dermatitis de contacto a acrilatos en una industria de fabricación de ascensores. A propósito de 8 casos
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J.L. Pérez-Formoso
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jlpformoso@gmail.com

Corresponding author.
, J. De Anca-Fernández, R. Maraví-Cecilia, J.M. Díaz-Torres
Instituto de Salud Laboral Asepeyo Cartuja, Sevilla, Spain
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Abstract
Introduction

Acrylates are widely used low-molecular-weight substances, initially introduced in industry in the 1930s and subsequently applied also in medicine and the home. One of their main features is the ability to undergo polymerization. The most commonly used acrylic compounds are cyanoacrylates, methacrylates, and acrylates.

Objective

To confirm suspicion of occupational disease in a group of workers in an elevator factory.

Material and methods

We studied 8 patients with dermatitis of the hands and finger pads. In their work, the patients came into contact with acrylates. Patch testing was applied with an acrylate panel (BIAL-Aristegui, Bilbao, Spain).

Results

Seven of the patients (87.5%) had a positive result with 1% ethylene glycol dimethacrylate. Positive results were also observed for 2% hydroxyethyl methacrylate (5 patients, 62.5%), 1% triethylene glycol dimethacrylate (4 patients, 50%), 10% ethyl methacrylate monomer (3 patients, 37.5%), 10% methyl methacrylate monomer (2 patients, 25%), 1% ethyl acrylate (1 patient, 12.5%), and 0.1% acrylic acid (1 patient, 12.5%)

Conclusions

We highlight the strong sensitizing capacity of acrylates and the importance of taking all necessary preventive measures in industries where these substances are used. Such measures should include avoidance of contact with the product in cases where sensitization has been confirmed.

Keywords:
Acrylates
Methacrylates
Allergic contact dermatitis
Irritant contact dermatitis
Resumen
Introducción

Los acrilatos son sustancias químicas de bajo peso molecular, con una amplia utilización en la industria (desde su introducción en los años treinta), la medicina y el medio doméstico, que destacan por sus propiedades de polimerización. Los compuestos acrílicos más utilizados son los cianoacrilatos, los metacrilatos y los acrilatos.

Objetivo

Establecer el diagnóstico de sospecha de enfermedad profesional en un grupo de trabajadores de una fábrica de ascensores.

Material y métodos

Se estudian un total de 8 pacientes que presentan clínica de dermatitis en las manos, así como pulpitis en los dedos, y que trabajan en contacto con acrilatos. Se realizaron pruebas epicutáneas con batería de acrilatos (BIAL-Aristegui, Bilbao, España).

Resultados

El 87,5% mostró positividad frente al dimetacrilato de etilenglicol al 1%. También mostraron positividad el hidroxietilmetacrilato al 2% (62,5%), el dimetacrilato de trietilenglicol al 1% (50%), el monómero de metil metacrilato al 10% (25%) y el monómero de etil metacrilato al 10% (37,5%), el acrilato de etilo al 1% (12,5%) y el ácido acrílico al 0,1% (12,5%).

Conclusiones

Destacamos el alto poder sensibilizante de los acrilatos y la importancia de extremar las medidas preventivas en las distintas industrias, así como la evitación del contacto con el producto en los casos de sensibilización demostrada.

Palabras clave:
Acrilatos
Metacrilatos
Dermatitis alérgica de contacto
Dermatitis irritativa de contacto
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Copyright © 2010. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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