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Vol. 101. Núm. 4.
Páginas 315-322 (mayo 2010)
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Vol. 101. Núm. 4.
Páginas 315-322 (mayo 2010)
Controversies in dermatology
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Studies of Methyl Aminolevulinate Photodynamic Therapy for Actinic Keratosis
Terapia fotodinámica: estudios con metilaminolevulinato en queratosis actínicas
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M. Fernández-Guarino
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montsefdez@msn.com

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, A. Harto, P. Jaén
Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Universidad de Alcalá de Henares, Madrid, Spain
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Abstract

Photodynamic therapy (PDT) for the treatment of actinic keratosis has been shown to be effective and safe in large clinical trials published in the last 5 years. However, evidence has since emerged that raises questions or that introduces new issues, such as the management of field cancerization, fluorescence diagnosis and results in transplant recipients. There also remains a need for more studies comparing PDT to additional treatments. We review the literature on these new topics in PDT.

Keywords:
Photodynamic therapy
Methyl aminolevulinate
Resumen

La terapia fotodinámica (TFD) se ha mostrado eficaz y segura en el tratamiento de las queratosis actínicas (QA) en importantes estudios en los últimos 5 años. Sin embargo, desde entonces, se han publicado varios trabajos con alguna evidencia contradictoria o añadiendo nuevos aspectos de esta terapia para su discusión, como es el tratamiento del campo de cancerización, el diagnóstico de fluorescencia, los resultados en pacientes trasplantados o la ausencia de estudios comparativos con otros tratamientos. En este trabajo revisamos estos nuevos aspectos de la TFD.

Palabras clave:
Terapia fotodinámica
Metilaminolevulinato
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Copyright © 2010. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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