Psoriatic Arthritis: What the Dermatologist Needs to Know, Part 1

López-Ferrer, A.; Torrente-Segarr, V.; Puig, L.

doi:10.1016/S1578-2190(10)70680-6

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La conexión PPAR e inmunopatología inflamatoria como nuevas dianas de tratamiento en dermatitis atópica y psoriasis" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "V.G. Villarrubia, S. Vidal-Asensi, V. Pérez-Bañasco, J. Cuevas-Santos, R. Cisterna-Cáncer" "autores" => array:5 [ 0 => array:2 [ "nombre" => "V.G." "apellidos" => "Villarrubia" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Vidal-Asensi" ] 2 => array:2 [ "nombre" => "V." "apellidos" => "Pérez-Bañasco" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Cuevas-Santos" ] 4 => array:2 [ "nombre" => "R." 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"apellidos" => "Arias-Santiago" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901070679X?idApp=UINPBA000044" "url" => "/15782190/0000010100000007/v1_201304241526/S157821901070679X/v1_201304241526/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "Review" "titulo" => "Psoriatic Arthritis: What the Dermatologist Needs to Know, Part 1" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "578" "paginaFinal" => "584" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. López-Ferrer, V. Torrente-Segarr, L. Puig" "autores" => array:3 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "López-Ferrer" "email" => array:1 [ 0 => "alopezfe@santpau.cat" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "¿" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "V." "apellidos" => "Torrente-Segarr" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Puig" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Artritis psoriásica: lo que el dermatólogo debe saber (Parte 1)" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-10-21" "fechaAceptado" => "2010-01-21" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84782" "palabras" => array:4 [ 0 => "Psoriasis" 1 => "Psoriatic arthritis" 2 => "Epidemiology" 3 => "Pathogenesis" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84783" "palabras" => array:4 [ 0 => "Psoriasis" 1 => "Artritis psoriásica" 2 => "Epidemiología" 3 => "Patogenia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Psoriatic arthritis is defined as inflammatory arthritis occurring in patients with psoriasis and is classified as a seronegative spondyloarthropathy associated with human leukocyte antigen B27. Between 25% and 35% of patients with psoriasis go on to develop psoriatic arthritis during the course of their disease. Given that the skin is affected before the joints in most cases, the dermatologist must be able to recognize the signs and symptoms in order to make a diagnosis and start the most appropriate treatment. This review aims to cover key aspects of the initial diagnostic workup and clinical evaluation. It examines the epidemiology, pathogenesis, and manifestations of psoriatic arthritis, as well as the complementary tests and diagnostic tools the dermatologist should be aware of in order to make the correct diagnosis." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "La artritis psoriásica (APso) se define como la artritis inflamatoria asociada a la psoriasis y se clasifica dentro de las espondiloartropatías seronegativas asociadas a HLA-B27. Se estima que entre el 25 y el 35% de los pacientes con psoriasis pueden desarrollar una artritis psoriásica a lo largo de la enfermedad. Dado que en la mayoría de los casos la afectación cutánea precede a la articular, es de gran importancia que el dermatólogo sepa reconocer los signos y síntomas de esta para iniciar el proceso diagnóstico y establecer el tratamiento más adecuado para el paciente. En esta revisión se pretende abarcar los aspectos necesarios para abordar el diagnóstico y evaluación inicial de la artritis psoriásica e incluye aspectos relacionados con la epidemiología, patogenia y clínica de la APso, así como las pruebas complementarias y encuestas diagnósticas que el dermatólogo debe conocer para establecer un diagnóstico correcto." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Abstract

Psoriatic arthritis is defined as inflammatory arthritis occurring in patients with psoriasis and is classified as a seronegative spondyloarthropathy associated with human leukocyte antigen B27. Between 25% and 35% of patients with psoriasis go on to develop psoriatic arthritis during the course of their disease. Given that the skin is affected before the joints in most cases, the dermatologist must be able to recognize the signs and symptoms in order to make a diagnosis and start the most appropriate treatment. This review aims to cover key aspects of the initial diagnostic workup and clinical evaluation. It examines the epidemiology, pathogenesis, and manifestations of psoriatic arthritis, as well as the complementary tests and diagnostic tools the dermatologist should be aware of in order to make the correct diagnosis.

Keywords:

Psoriasis

Psoriatic arthritis

Epidemiology

Pathogenesis

Resumen

La artritis psoriásica (APso) se define como la artritis inflamatoria asociada a la psoriasis y se clasifica dentro de las espondiloartropatías seronegativas asociadas a HLA-B27. Se estima que entre el 25 y el 35% de los pacientes con psoriasis pueden desarrollar una artritis psoriásica a lo largo de la enfermedad. Dado que en la mayoría de los casos la afectación cutánea precede a la articular, es de gran importancia que el dermatólogo sepa reconocer los signos y síntomas de esta para iniciar el proceso diagnóstico y establecer el tratamiento más adecuado para el paciente. En esta revisión se pretende abarcar los aspectos necesarios para abordar el diagnóstico y evaluación inicial de la artritis psoriásica e incluye aspectos relacionados con la epidemiología, patogenia y clínica de la APso, así como las pruebas complementarias y encuestas diagnósticas que el dermatólogo debe conocer para establecer un diagnóstico correcto.

Palabras clave:

Psoriasis

Artritis psoriásica

Epidemiología

Patogenia

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