Pigmented or Hemosiderotic Atypical Fibroxanthoma

Pastor-Nieto, M.A.; Kilmurray, L.G.; Requena, L.

doi:10.1016/S1578-2190(09)70070-8

array:23 ["pii" => "S1578219009700708" "issn" => "15782190" "doi" => "10.1016/S1578-2190(09)70070-8" "estado" => "S300" "fechaPublicacion" => "2009-05-01" "aid" => "70070" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2009;100:321-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2821 "formatos" => array:3 [ "EPUB" => 38 "HTML" => 1494 "PDF" => 1289 ] ] "itemSiguiente" => array:18 [ "pii" => "S157821900970071X" "issn" => "15782190" "doi" => "10.1016/S1578-2190(09)70071-X" "estado" => "S300" "fechaPublicacion" => "2009-05-01" "aid" => "70071" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2009;100:325-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2023 "formatos" => array:3 [ "EPUB" => 34 "HTML" => 1393 "PDF" => 596 ] ] "en" => array:8 [ "idiomaDefecto" => true "cabecera" => "Cases for diagnosis" "titulo" => "Acral Psoriasiform Lesions" "tienePdf" => "en" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "325" "paginaFinal" => "326" ] ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.P. Sánchez-Salas, F.J. García-Latasa de Aranibar, M.A. Ania" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M.P." "apellidos" => "Sánchez-Salas" ] 1 => array:2 [ "nombre" => "F.J." "apellidos" => "García-Latasa de Aranibar" ] 2 => array:2 [ "nombre" => "M.A." "apellidos" => "Ania" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821900970071X?idApp=UINPBA000044" "url" => "/15782190/0000010000000004/v1_201304241454/S157821900970071X/v1_201304241454/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219009700691" "issn" => "15782190" "doi" => "10.1016/S1578-2190(09)70069-1" "estado" => "S300" "fechaPublicacion" => "2009-05-01" "aid" => "70069" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2009;100:317-20" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3281 "formatos" => array:3 [ "EPUB" => 33 "HTML" => 1934 "PDF" => 1314 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "Case reports" "titulo" => "Allergic Contact Dermatitis to Diethylthiourea in a Neoprene Wader" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "317" "paginaFinal" => "320" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatitis Alérgica de Contacto a Dietitiourea por un Traje de Pesca de Neopreno" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.C. Martínez-González, J.J. Goday-Buján, M. Almagro, E. Fonseca" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M.C." "apellidos" => "Martínez-González" ] 1 => array:2 [ "nombre" => "J.J." "apellidos" => "Goday-Buján" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Almagro" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Fonseca" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700691?idApp=UINPBA000044" "url" => "/15782190/0000010000000004/v1_201304241454/S1578219009700691/v1_201304241454/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "Case reports" "titulo" => "Pigmented or Hemosiderotic Atypical Fibroxanthoma" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "321" "paginaFinal" => "324" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M.A. Pastor-Nieto, L.G. Kilmurray, L. Requena" "autores" => array:3 [ 0 => array:4 [ "nombre" => "M.A." "apellidos" => "Pastor-Nieto" "email" => array:1 [ 0 => "mapastornieto@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "¿" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "L.G." "apellidos" => "Kilmurray" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Requena" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "c" "identificador" => "aff3" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital General Universitario de Guadalajara, Guadalajara, Spain" "etiqueta" => "a" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital del Sureste, Arganda del Rey, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Fundación Jiménez Díaz, Madrid, Spain" "etiqueta" => "c" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Hospital General Universitario de Guadalajara, C/ Donante de Sangre, s/n, 19002 Guadalajara, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Fibroxantoma Atípico Pigmentado o Hemosiderótico" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2008-07-21" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84447" "palabras" => array:3 [ 0 => "atypical fibroxanthoma" 1 => "pigmented" 2 => "hemosiderotic" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84448" "palabras" => array:3 [ 0 => "fibroxantoma atípico" 1 => "pigmentado" 2 => "hemosiderótico" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Pigmented atypical fibroxanthoma is a rare variant of atypical fibroxanthoma and is characterized by extensive areas of hemorrhage, erythrophagocytosis, and hemosiderin accumulation in the cytoplasm of the neoplastic cells. It affects elderly individuals and presents as irregularly pigmented, dome-shaped nodules or plaques on areas of skin exposed to the sun. We present a case of pigmented atypical fibroxanthoma on the cheek of an 81-year-old man. Six years after excision of the lesion, the patient remains in complete remission, with no signs of residual tumor or metastasis. The 9 cases of pigmented atypical fibroxanthoma reported in the literature are reviewed, and the histopathological features and differential diagnosis are discussed." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "El fibroxantoma atípico pigmentado es una variante rara de fibroxantoma atípico caracterizada por áreas extensas de hemorragia, eritrofagocitosis y depósitos de hemosiderina en el citoplasma de las células neoplásicas. Afecta a pacientes de edad avanzada, y se manifiesta como nódulos cupuliformes o placas pigmentadas, de coloración heterogénea, en áreas de piel fotoexpuesta.Se presenta un caso de fibroxantoma atípico pigmentado de localización malar en un varón de 81 años de edad. Seis años después de la extirpación quirúrgica de la lesión, el paciente permanece en remisión completa, sin que se aprecien signos clínicos de persistencia tumoral o metástasis.Se revisan los 9 casos de fibroxantoma atípico pigmentado publicados en la literatura y se discuten las características histopatológicas y el diagnóstico diferencial de esta rara entidad." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fibroxantoma atípico. Estudio clínico-patológico de 10 casos" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. Gómez-de la Fuente" 1 => "M. Sols" 2 => "F. Pinedo" 3 => "J.G. Álvarez-Fernández" 4 => "F.J. Vicente" 5 => "E. Naz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2005" "volumen" => "96" "paginaInicial" => "153" "paginaFinal" => "158" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16476356" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical fibroxanthoma: a clinicopathological study of 89 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "B. Mirza" 1 => "D. Weedon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Austr J Dermatol" "fecha" => "2005" "volumen" => "46" "paginaInicial" => "235" "paginaFinal" => "238" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spindle-cell non-pleomorphic atypical fibroxanthoma: analysis of a series and delineation of a distinctive variant" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. Calonje" 1 => "C. Wadden" 2 => "E. Wilson-Jones" 3 => "C.D. Fletcher" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Histopathology" "fecha" => "1993" "volumen" => "22" "paginaInicial" => "247" "paginaFinal" => "254" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7684354" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016510709027473" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clear-cell atypical fibroxanthoma: an uncommon histopathologic variant of atypical fibroxanthoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L. Requena" 1 => "O.P. Sangueza" 2 => "E.S. Yus" 3 => "V. Furió" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Cutan Pathol" "fecha" => "1997" "volumen" => "24" "paginaInicial" => "176" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9085154" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Granular cell atypical fibroxanthoma: report of two cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.J. Ríos-Martín" 1 => "M. Díaz-Delgado" 2 => "D. Moreno-Ramírez" 3 => "A. García-Escudero" 4 => "R. González-Cámpora" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.dad.0000246175.73447.3a" "Revista" => array:7 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2007" "volumen" => "29" "paginaInicial" => "84" "paginaFinal" => "87" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17284969" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016510711024928" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical fibroxanthoma with osteoclast-like giant cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.F. Val-Bernal" 1 => "J. Corral" 2 => "F. Fernández" 3 => "C. Gómez-Bellvert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Derm Venereol" "fecha" => "1994" "volumen" => "74" "paginaInicial" => "467" "paginaFinal" => "470" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7701884" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical fibroxanthoma with prominent sclerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.K. Bruecks" 1 => "S.A. Medlicott" 2 => "M.J. Trotter" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Cutan Pathol" "fecha" => "2003" "volumen" => "30" "paginaInicial" => "336" "paginaFinal" => "339" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12753176" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pigmented atypical fibroxanthoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Díaz-Cascajo" 1 => "S. Borghi" 2 => "M. Bonczkowitz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Histopathology" "fecha" => "1998" "volumen" => "33" "paginaInicial" => "537" "paginaFinal" => "541" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9870148" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pigmented atypical fibroxanthoma. A tumor that may be easily mistaken for malignant melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Díaz-Cascajo" 1 => "W. Weyers" 2 => "S. Borghi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2003" "volumen" => "25" "paginaInicial" => "1" "paginaFinal" => "5" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12544091" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S073510970700054X" "estado" => "S300" "issn" => "07351097" ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pigmented atypical fibroxanthoma, a dermatofibroma variant?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "B. Zelger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2004" "volumen" => "26" "paginaInicial" => "84" "paginaFinal" => "86" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14726831" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pigmented atypical fibroxanthoma: not a variant of dermatofibroma: concept that atypical fibroxanthoma is squamous cell carcinoma is a misconstruction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C. Díaz-Cascajo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2004" "volumen" => "26" "paginaInicial" => "86" "paginaFinal" => "87" ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multinodular hemosiderotic dermatofibroma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L. Requena" 1 => "A. Aguilar" 2 => "M.J. López Redondo" 3 => "C. Schoendorff" 4 => "E. Sánchez Yus" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dermatologica" "fecha" => "1990" "volumen" => "181" "paginaInicial" => "320" "paginaFinal" => "323" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2073965" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hobnail hemangioma (targetoid hemosiderotic hemangioma)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "O. Sangüeza" 1 => "L. Requena" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Pathology of vascular skin lesions. Clinicopathologic correlations" "paginaInicial" => "157" "edicion" => "1st ed." "serieFecha" => "2003" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hemosiderotic fibrolipomatous tumor (so-called hemosiderotic fibrohistiocytic lipomatous tumor): analysis of 13 new cases in support of a distinct entity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T.J. Browne" 1 => "C.D.M. Fletcher" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2559.2006.02360.x" "Revista" => array:6 [ "tituloSerie" => "Histopathology" "fecha" => "2006" "volumen" => "48" "paginaInicial" => "453" "paginaFinal" => "461" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16487368" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Targetoid hemosiderotic nevus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C. Tomasini" 1 => "C. Borganelli" 2 => "M. Pippione" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000083510" "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "2005" "volumen" => "210" "paginaInicial" => "200" "paginaFinal" => "205" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15785047" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010000000004/v1_201304241454/S1578219009700708/v1_201304241454/en/main.assets" "Apartado" => array:4 [ "identificador" => "6183" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010000000004/v1_201304241454/S1578219009700708/v1_201304241454/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700708?idApp=UINPBA000044"]

Información del artículo

Resumen

Bibliografía

Descargar PDF

Estadísticas

Abstract

Pigmented atypical fibroxanthoma is a rare variant of atypical fibroxanthoma and is characterized by extensive areas of hemorrhage, erythrophagocytosis, and hemosiderin accumulation in the cytoplasm of the neoplastic cells. It affects elderly individuals and presents as irregularly pigmented, dome-shaped nodules or plaques on areas of skin exposed to the sun. We present a case of pigmented atypical fibroxanthoma on the cheek of an 81-year-old man. Six years after excision of the lesion, the patient remains in complete remission, with no signs of residual tumor or metastasis. The 9 cases of pigmented atypical fibroxanthoma reported in the literature are reviewed, and the histopathological features and differential diagnosis are discussed.

Key words:

atypical fibroxanthoma

pigmented

hemosiderotic

Resumen

El fibroxantoma atípico pigmentado es una variante rara de fibroxantoma atípico caracterizada por áreas extensas de hemorragia, eritrofagocitosis y depósitos de hemosiderina en el citoplasma de las células neoplásicas. Afecta a pacientes de edad avanzada, y se manifiesta como nódulos cupuliformes o placas pigmentadas, de coloración heterogénea, en áreas de piel fotoexpuesta.Se presenta un caso de fibroxantoma atípico pigmentado de localización malar en un varón de 81 años de edad. Seis años después de la extirpación quirúrgica de la lesión, el paciente permanece en remisión completa, sin que se aprecien signos clínicos de persistencia tumoral o metástasis.Se revisan los 9 casos de fibroxantoma atípico pigmentado publicados en la literatura y se discuten las características histopatológicas y el diagnóstico diferencial de esta rara entidad.

Palabras clave:

fibroxantoma atípico

pigmentado

hemosiderótico

El Texto completo está disponible en PDF

References

[1.]

E. Gómez-de la Fuente, M. Sols, F. Pinedo, J.G. Álvarez-Fernández, F.J. Vicente, E. Naz, et al.

Fibroxantoma atípico. Estudio clínico-patológico de 10 casos.

Actas Dermosifiliogr, 96 (2005), pp. 153-158

Medline

[2.]

B. Mirza, D. Weedon.

Atypical fibroxanthoma: a clinicopathological study of 89 cases.

Austr J Dermatol, 46 (2005), pp. 235-238

[3.]

E. Calonje, C. Wadden, E. Wilson-Jones, C.D. Fletcher.

Spindle-cell non-pleomorphic atypical fibroxanthoma: analysis of a series and delineation of a distinctive variant.

Histopathology, 22 (1993), pp. 247-254

Medline

[4.]

L. Requena, O.P. Sangueza, E.S. Yus, V. Furió.

Clear-cell atypical fibroxanthoma: an uncommon histopathologic variant of atypical fibroxanthoma.

J Cutan Pathol, 24 (1997), pp. 176

Medline

[5.]

J.J. Ríos-Martín, M. Díaz-Delgado, D. Moreno-Ramírez, A. García-Escudero, R. González-Cámpora.

Granular cell atypical fibroxanthoma: report of two cases.

Am J Dermatopathol, 29 (2007), pp. 84-87

http://dx.doi.org/10.1097/01.dad.0000246175.73447.3a | Medline

[6.]

J.F. Val-Bernal, J. Corral, F. Fernández, C. Gómez-Bellvert.

Atypical fibroxanthoma with osteoclast-like giant cells.

Acta Derm Venereol, 74 (1994), pp. 467-470

Medline

[7.]

A.K. Bruecks, S.A. Medlicott, M.J. Trotter.

Atypical fibroxanthoma with prominent sclerosis.

J Cutan Pathol, 30 (2003), pp. 336-339

Medline

[8.]

C. Díaz-Cascajo, S. Borghi, M. Bonczkowitz.

Pigmented atypical fibroxanthoma.

Histopathology, 33 (1998), pp. 537-541

Medline

[9.]

C. Díaz-Cascajo, W. Weyers, S. Borghi.

Pigmented atypical fibroxanthoma. A tumor that may be easily mistaken for malignant melanoma.

Am J Dermatopathol, 25 (2003), pp. 1-5

Medline

[10.]

B. Zelger.

Pigmented atypical fibroxanthoma, a dermatofibroma variant?.

Am J Dermatopathol, 26 (2004), pp. 84-86

Medline

[11.]

C. Díaz-Cascajo.

Pigmented atypical fibroxanthoma: not a variant of dermatofibroma: concept that atypical fibroxanthoma is squamous cell carcinoma is a misconstruction.

Am J Dermatopathol, 26 (2004), pp. 86-87

[12.]

L. Requena, A. Aguilar, M.J. López Redondo, C. Schoendorff, E. Sánchez Yus.

Multinodular hemosiderotic dermatofibroma.

Dermatologica, 181 (1990), pp. 320-323

Medline

[13.]

O. Sangüeza, L. Requena.

Hobnail hemangioma (targetoid hemosiderotic hemangioma).

Pathology of vascular skin lesions. Clinicopathologic correlations, 1st ed., pp. 157

[14.]

T.J. Browne, C.D.M. Fletcher.

Hemosiderotic fibrolipomatous tumor (so-called hemosiderotic fibrohistiocytic lipomatous tumor): analysis of 13 new cases in support of a distinct entity.

Histopathology, 48 (2006), pp. 453-461

http://dx.doi.org/10.1111/j.1365-2559.2006.02360.x | Medline

[15.]

C. Tomasini, C. Borganelli, M. Pippione.

Targetoid hemosiderotic nevus.

Dermatology, 210 (2005), pp. 200-205

http://dx.doi.org/10.1159/000083510 | Medline

Indexada en:

Síguenos:

Indexada en:

Síguenos:

Suscríbase a la newsletter