Perifollicular Xanthomatosis as a Key Histological Finding in Fox-Fordyce Disease

Mataix, J.; Silvestre, J.F.; Niveiro, M.; Lucas, A.; Pérez-Crespo, M.

doi:10.1016/S1578-2190(08)70215-4

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"apellidos" => "Pérez-Crespo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain" "etiqueta" => "a" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Anatomía Patológica, Hospital General Universitario de Alicante, Alicante, Spain" "etiqueta" => "b" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Dermatología, Hospital General Universitario, Avda. Pintor Baeza s/n 03010 Alicante, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Xantomatosis Perifolicular: Hallazgo Histológico Clave en la Enfermedad de Fox-Fordyce" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2007-04-03" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84114" "palabras" => array:3 [ 0 => "Fox–Fordyce disease" 1 => "apocrine miliaria" 2 => "perifollicular xanthomatosis" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84113" "palabras" => array:3 [ 0 => "enfermedad de Fox-Fordyce" 1 => "miliaria apocrina" 2 => "xantomatosis perifolicular" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Fox–Fordyce disease is a rare skin condition characterized by the presence of multiple pruritic follicular papules in areas rich in apocrine glands, such as the axillae, mammary areolae, or genital regions. There is a high degree of variability in the histological findings seen in Fox–Fordyce disease. In addition to those described as typical of this entity, such as dilation of the infundibulum and hyperkeratosis and spongiosis of the infundibular epithelium, many other histological changes can be observed. We report the case of a 21-year-old woman with Fox–Fordyce disease and highlight the importance of perifollicular xanthomatosis as a key histological finding in the diagnosis of the disease." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "La enfermedad de Fox-Fordyce es una rara dermatosis caracterizada por la presencia de múltiples pápulas foliculares pruriginosas en áreas corporales con riqueza de glándulas apocrinas como axilas, areolas mamarias o región genital. Los hallazgos histopatológicos que definen la enfermedad de Fox-Fordyce son muy variados. Además de los hallazgos descritos como típicos de esta entidad, como la dilatación del infundíbulo y la hiperqueratosis y espongiosis del epitelio infundibular, se pueden observar otros muchos hallazgos histológicos. Presentamos el caso de una mujer de 21 años de edad afectada por esta enfermedad y recalcamos la importancia de la xantomatosis perinfundibular como hallazgo histológico clave en el diagnóstico de esta entidad." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:21 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two cases of a rare papular disease affecting the axillary region" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G.H. Fox" 1 => "J.A. Fordyce" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Cut Genito-Urinary Dis" "fecha" => "1902" "volumen" => "20" "paginaInicial" => "1" "paginaFinal" => "5" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Apocrine sweat retention in men. II. Fox–Fordyce disease (apocrine miliaria)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.B. Shelley" 1 => "E.J. Levy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1956" "volumen" => "73" "paginaInicial" => "38" "paginaFinal" => "49" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Ozcan" 1 => "M. Senol" 2 => "N.E. Aydin" 3 => "S. Karaca" 4 => "S. Sener" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2003" "volumen" => "17" "paginaInicial" => "244" "paginaFinal" => "245" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12705772" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Axillary perifollicular xanthomatosis resembling Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Kossard" 1 => "P. Dwyer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1440-0960.2004.00064.x" "Revista" => array:6 [ "tituloSerie" => "Australas J Dermatol" "fecha" => "2004" "volumen" => "45" "paginaInicial" => "146" "paginaFinal" => "148" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15068468" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patterns histopathologic of Fo–x-Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. Böer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2004" "volumen" => "26" "paginaInicial" => "482" "paginaFinal" => "492" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15618931" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perifollicular xanthomatosis is the hallmark of axillary Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.B. Bormate Jr" 1 => "T.H. McCalmont" 2 => "P.E. LeBoit" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "2006" "volumen" => "28" "paginaInicial" => "232" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Resolving Quandaries in Dermatology, Pathology, and Dermatopathology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.B. Ackerman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "1995" "editorial" => "Promethean Medical Press" "editorialLocalizacion" => "Philadelphia" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histologic diagnosis of inflammatory skin diseases. An algorithmic method based on pattern analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.B. Ackerman" 1 => "N. Chongchitant" 2 => "J. Sanchez" 3 => "Y. Guo" 4 => "B. Bennin" 5 => "M. Reichel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "2nd ed." "fecha" => "1997" "editorial" => "Williams & Wilkins" "editorialLocalizacion" => "Baltimore" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.C. Macmillan" 1 => "H.R. Vickers" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1971" "volumen" => "84" "paginaInicial" => "181" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5548469" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Apoeccrine sweat duct obstruction as a cause for Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Kamada" 1 => "K. Saga" 2 => "K. Jimbow" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mjd.2003.93" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2003" "volumen" => "48" "paginaInicial" => "453" "paginaFinal" => "455" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12637930" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease. Treatment with an oral contraceptive" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.I. Kronthal" 1 => "J.R. Pomeranz" 2 => "G. Sitomer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1965" "volumen" => "91" "paginaInicial" => "243" "paginaFinal" => "245" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14246163" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hormonal levels in Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T.W. Turner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1976" "volumen" => "94" "paginaInicial" => "317" "paginaFinal" => "318" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1252362" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Enfermedad de Fox–Fordyce" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. Rubio" 1 => "M. Mayor" 2 => "M.A. Martín" 3 => "M.J. González-Beato" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2004" "volumen" => "95" "paginaInicial" => "314" "paginaFinal" => "316" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox-Foxdyce disease in a prepubertal girl" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K. Sandhu" 1 => "S. Gupta" 2 => "A.J. Kanwar" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1525-1470.2005.22125.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Dermatol" "fecha" => "2005" "volumen" => "22" "paginaInicial" => "89" "paginaFinal" => "90" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15660912" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease in male identical twins" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.H. Graham" 1 => "J.C. Shafer" 2 => "E.B. Helwig" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1960" "volumen" => "82" "paginaInicial" => "212" "paginaFinal" => "221" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13828810" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A new treatment of Fox–Fordyce disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.J. Helfman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "South Med J" "fecha" => "1962" "volumen" => "55" "paginaInicial" => "681" "paginaFinal" => "684" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13906206" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease. Control with tretinoin cream" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Giacobetti" 1 => "W.A. Caro" 2 => "H.H. Roenigk Jr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1979" "volumen" => "115" "paginaInicial" => "1365" "paginaFinal" => "1366" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/507892" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease in a male patient- response to oral retinoid treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "I. Effendy" 1 => "B. Ossowski" 2 => "R. Happle" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol" "fecha" => "1994" "volumen" => "19" "paginaInicial" => "67" "paginaFinal" => "69" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8313643" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fox–Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Feldmann" 1 => "I. Masouye" 2 => "P. Chavaz" 3 => "J.H. 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Información del artículo

Estadísticas

Abstract

Fox–Fordyce disease is a rare skin condition characterized by the presence of multiple pruritic follicular papules in areas rich in apocrine glands, such as the axillae, mammary areolae, or genital regions. There is a high degree of variability in the histological findings seen in Fox–Fordyce disease. In addition to those described as typical of this entity, such as dilation of the infundibulum and hyperkeratosis and spongiosis of the infundibular epithelium, many other histological changes can be observed. We report the case of a 21-year-old woman with Fox–Fordyce disease and highlight the importance of perifollicular xanthomatosis as a key histological finding in the diagnosis of the disease.

Key words:

Fox–Fordyce disease

apocrine miliaria

perifollicular xanthomatosis

Resumen

La enfermedad de Fox-Fordyce es una rara dermatosis caracterizada por la presencia de múltiples pápulas foliculares pruriginosas en áreas corporales con riqueza de glándulas apocrinas como axilas, areolas mamarias o región genital. Los hallazgos histopatológicos que definen la enfermedad de Fox-Fordyce son muy variados. Además de los hallazgos descritos como típicos de esta entidad, como la dilatación del infundíbulo y la hiperqueratosis y espongiosis del epitelio infundibular, se pueden observar otros muchos hallazgos histológicos. Presentamos el caso de una mujer de 21 años de edad afectada por esta enfermedad y recalcamos la importancia de la xantomatosis perinfundibular como hallazgo histológico clave en el diagnóstico de esta entidad.

Palabras clave:

enfermedad de Fox-Fordyce

miliaria apocrina

xantomatosis perifolicular

El Texto completo está disponible en PDF

References

[1.]

G.H. Fox, J.A. Fordyce.

Two cases of a rare papular disease affecting the axillary region.

J Cut Genito-Urinary Dis, 20 (1902), pp. 1-5

[2.]

W.B. Shelley, E.J. Levy.

Apocrine sweat retention in men. II. Fox–Fordyce disease (apocrine miliaria).

Arch Dermatol, 73 (1956), pp. 38-49

[3.]

A. Ozcan, M. Senol, N.E. Aydin, S. Karaca, S. Sener.

Fox–Fordyce disease.

J Eur Acad Dermatol Venereol, 17 (2003), pp. 244-245

Medline

[4.]

S. Kossard, P. Dwyer.

Axillary perifollicular xanthomatosis resembling Fox–Fordyce disease.

Australas J Dermatol, 45 (2004), pp. 146-148

http://dx.doi.org/10.1111/j.1440-0960.2004.00064.x | Medline

[5.]

A. Böer.

Patterns histopathologic of Fo–x-Fordyce disease.

Am J Dermatopathol, 26 (2004), pp. 482-492

Medline

[6.]

A.B. Bormate Jr, T.H. McCalmont, P.E. LeBoit.

Perifollicular xanthomatosis is the hallmark of axillary Fox–Fordyce disease.

Am J Dermatopathol, 28 (2006), pp. 232

[7.]

A.B. Ackerman.

Resolving Quandaries in Dermatology, Pathology, and Dermatopathology.

Promethean Medical Press, (1995),

[8.]

A.B. Ackerman, N. Chongchitant, J. Sanchez, Y. Guo, B. Bennin, M. Reichel, et al.

Histologic diagnosis of inflammatory skin diseases. An algorithmic method based on pattern analysis.

2nd ed., Williams & Wilkins, (1997),

[9.]

D.C. Macmillan, H.R. Vickers.

Fox–Fordyce disease.

Br J Dermatol, 84 (1971), pp. 181

Medline

[10.]

A. Kamada, K. Saga, K. Jimbow.

Apoeccrine sweat duct obstruction as a cause for Fox–Fordyce disease.

J Am Acad Dermatol, 48 (2003), pp. 453-455

http://dx.doi.org/10.1067/mjd.2003.93 | Medline

[11.]

H.I. Kronthal, J.R. Pomeranz, G. Sitomer.

Fox–Fordyce disease. Treatment with an oral contraceptive.

Arch Dermatol, 91 (1965), pp. 243-245

Medline

[12.]

T.W. Turner.

Hormonal levels in Fox–Fordyce disease.

Br J Dermatol, 94 (1976), pp. 317-318

Medline

[13.]

C. Rubio, M. Mayor, M.A. Martín, M.J. González-Beato.

Enfermedad de Fox–Fordyce.

Actas Dermosifiliogr, 95 (2004), pp. 314-316

[14.]

K. Sandhu, S. Gupta, A.J. Kanwar.

Fox-Foxdyce disease in a prepubertal girl.

Pediatr Dermatol, 22 (2005), pp. 89-90

http://dx.doi.org/10.1111/j.1525-1470.2005.22125.x | Medline

[15.]

J.H. Graham, J.C. Shafer, E.B. Helwig.

Fox–Fordyce disease in male identical twins.

Arch Dermatol, 82 (1960), pp. 212-221

Medline

[16.]

R.J. Helfman.

A new treatment of Fox–Fordyce disease.

South Med J, 55 (1962), pp. 681-684

Medline

[17.]

R. Giacobetti, W.A. Caro, H.H. Roenigk Jr.

Fox–Fordyce disease. Control with tretinoin cream.

Arch Dermatol, 115 (1979), pp. 1365-1366

Medline

[18.]

I. Effendy, B. Ossowski, R. Happle.

Fox–Fordyce disease in a male patient- response to oral retinoid treatment.

Clin Exp Dermatol, 19 (1994), pp. 67-69

Medline

[19.]

R. Feldmann, I. Masouye, P. Chavaz, J.H. Saurat.

Fox–Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution.

Dermatology, 184 (1992), pp. 310-313

Medline

[20.]

L. Pock, M. Svrckova, R. Machackova, J. Hercogova.

Pimecrolimus is effective in Fox–Fordyce disease.

Int J Dermatol, 45 (2006), pp. 1134-1135

http://dx.doi.org/10.1111/j.1365-4632.2006.02878.x | Medline

[21.]

K.M. Chae, M.A. Marschall, S.F. Marschall.

Axillary Fox–Fordyce disease treated with liposuction-assisted curettage.

Arch Dermatol, 138 (2002), pp. 452-454

Medline

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