Información de la revista
Vol. 114. Núm. 5.
Páginas 448 (mayo 2023)
Descargar PDF
Más opciones de artículo
Vol. 114. Núm. 5.
Páginas 448 (mayo 2023)
Images in Dermatology
Acceso a texto completo
Oral Changes Associated With Hypovitaminosis
Alteraciones orales asociadas a la hipovitaminosis
B.C. Biancoa,
Autor para correspondencia

Corresponding author.
, A.R. Camargob, L.J. Grandoc
a Post-graduation Program, Federal University of Santa Catarina, Florianópolis, Santa Catarina State, Brazil
b Professor, Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil
c Professor, Department of Pathology, Federal University of Santa Catarina State, Florianópolis, Brazil
Contenido relaccionado
Actas Dermosifiliogr. 2023;114:T44810.1016/
B.C. Bianco, A.R. Camargo, L.J. Grando
Este artículo ha recibido
Información del artículo
Texto completo
Descargar PDF
Figuras (2)
Texto completo

A 35-year-old woman complained of a burning mouth similar to a thermal burn for 2 months. On physical examination, multiple areas of erosion and flaking of the mucosa in the palatoglossal arch (Fig. 1) and tongue belly (Fig. 2) were observed bilaterally. In laboratory tests, the results showed vitamin B12 deficiency (87pg/mL), vitamin D deficiency (17ng/mL), serum iron deficiency (47mcg/dL), elevated iron-binding capacity (439mg/dL), low serum ferritin (6.2mg/dL), elevated homocysteine (50μmol/l). The patient was then referred for ferritin replacement, vitamins D and B complex; presenting improvement in oral lesions, which indicated, together with previous data, the diagnosis of oral manifestation of iron deficiency and pernicious anemia.

Figure 1
Figure 2

Iron deficiency anemia is caused by iron deficiency, which is essential for the functioning of epithelial cells, its absence can cause signs such as tongue desperation – or glossitis atrophic- and is often preceded by a burning sensation. On the other hand, anemia pernicious is a type of anemia caused by vitamin B12 deficiency, caused by autoantibodies against intrinsic factors and/or gastric parietal squid. Glossitis, when present, is a sign that is part of the classic triad of this deficiency consisting of the presence of megaloblastic anemia, gastrointestinal symptoms or glossitis, and symptoms of athletic neuropsychic.

Copyright © 2022. AEDV
Actas Dermo-Sifiliográficas
Opciones de artículo
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?