Case for Diagnosis
Painful Nodules on the Thighs
Nódulos dolorosos en muslos
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"apellidos" => "Ara" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Departamento de Dermatología, Hospital Royo Villanova, Zaragoza, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Dermatología del Hospital de Alcañiz, Teruel, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Nódulos dolorosos en muslos" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 900 "Ancho" => 900 "Tamanyo" => 273933 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histology. A. Hematoxylin-eosin, original magnification, ×10. B and C. Hematoxylin-eosin, original magnification, ×40.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Case Presentation</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 23-year-old woman consulted for the gradual appearance of painful lesions on the external aspect of the thighs. The lesions had first appeared 5 weeks earlier. The patient reported similar flare-ups over 3 consecutive years; these appeared during the coldest months of the year and resolved without scarring as the seasonal temperature increased. No other manifestations were observed. The patient was a horseback rider and rode and cared for horses on a daily basis.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">The examination revealed erythematous-violaceous lesions that were painful to the touch and tended to coalesce and form plaques on the outer part of the upper thigh (both legs) (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Erythematous-violaceous reticulated macules with a vascular appearance were observed on the rest of the thigh. The local temperature was lower in the affected areas.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Histopathology</span><p id="par0015" class="elsevierStylePara elsevierViewall">The histopathology workup (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A) revealed a perivascular and periadnexal dermal lymphocytic infiltrate beneath a normal epidermis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>C), as well as venulitis in the deep reticular dermis and hypodermis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>B). No signs of panniculitis were observed. Alcian-blue staining did not reveal mucin deposits.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Additional Tests</span><p id="par0020" class="elsevierStylePara elsevierViewall">The results of the laboratory work-up were normal (negative for autoimmunity, cold agglutinins, cryoglobulins, and serology). Capillaroscopy performed on the hands revealed normal findings, as did Doppler ultrasound of the lower limbs.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">What is Your Diagnosis?</span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Cold-associated perniosis of the thighs (CAPT).</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Course and Treatment</span><p id="par0030" class="elsevierStylePara elsevierViewall">The patient was recommended to wear looser clothing and prescribed medium-potency topical corticosteroids. The lesions had improved at the 1-month check-up.</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Comment</span><p id="par0035" class="elsevierStylePara elsevierViewall">CAPT is the term proposed in 2016 by Ferrara and Cerroni<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> to describe a condition for which no consensus had been reached and that had been reported with various names: equestrian panniculitis, equestrian-type perniosis, or equestrian-type chilblains. Diagnosis is based on previous exposure to cold, cutaneous lesions on the side of the thighs, and a compatible history.</p><p id="par0040" class="elsevierStylePara elsevierViewall">The usual clinical picture of CAPT does not differ significantly from that originally described in 1980 by Beacham et al.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> under the name of equestrian cold panniculitis. It is characterized by the presence of infiltrated erythematous-violaceous plaques that may be pruritic or painful. The plaques are found mainly on the outer part of the upper thigh and are not accompanied by other abnormalities.</p><p id="par0045" class="elsevierStylePara elsevierViewall">The term <span class="elsevierStyleItalic">equestrian</span> was replaced by <span class="elsevierStyleItalic">cold-associated</span>. Other causes have been identified, for example, riding a bicycle, occupational exposure to humid environments, toboganning,<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> wearing jeans with a low waistband,<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> and application of icepacks.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">The term <span class="elsevierStyleItalic">perniosis</span> is now preferred to <span class="elsevierStyleItalic">panniculitis</span> because signs of panniculitis were not observed in many of the cases analyzed. The most common finding is a perivascular and periadnexal lymphocytic infiltrate in the superficial and deep dermis. Other findings include mucin deposits in the dermis and inflammation of small- and medium-caliber venules. Some cases also present lymphocytic lobular panniculitis, which is probably an advanced stage of deep venulitis. Histology makes it possible to differentiate the condition from other conditions in which cold leads to necrosis of hypodermal fat, such as Haxthausen disease or panniculitis caused by sucking ice cream; the term <span class="elsevierStyleItalic">cold-induced panniculitis</span> should be reserved for these conditions.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,6</span></a> Furthermore, cases of cold-induced dermatosis have been reported in horseback riders or persons who have applied cold locally in order to treat low back pain. This can take the form of panniculitis and chilblains (perniosis), which, in histologic terms, resemble lupus.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The outer part of the upper thigh is the most common location, for several reasons. The area is more exposed to cold, thus leading to vasoconstriction and increased blood viscosity. In addition, it is exposed to tight clothes that place continuous pressure on the area and reduce blood flow in the subcutaneous fat. Moreover, the area is characterized by abundant adipose tissue, which isolates blood vessels and makes them more susceptible to the effects of cold.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">Treatment is based on recommending loose clothing. Topical corticosteroids can also be applied. Vasodilators are not useful.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> The condition usually resolves without scarring after a few weeks.</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Conflicts of Interest</span><p id="par0065" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:8 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Case Presentation" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Physical Examination" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Histopathology" ] 3 => array:2 [ "identificador" => "sec0020" "titulo" => "Additional Tests" ] 4 => array:3 [ "identificador" => "sec0025" "titulo" => "What is Your Diagnosis?" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0030" "titulo" => "Diagnosis" ] 1 => array:2 [ "identificador" => "sec0035" "titulo" => "Course and Treatment" ] ] ] 5 => array:2 [ "identificador" => "sec0040" "titulo" => "Comment" ] 6 => array:2 [ "identificador" => "sec0045" "titulo" => "Conflicts of Interest" ] 7 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-02-22" "fechaAceptado" => "2019-05-23" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Conejero R, Rivera-Rodríguez Á, Ara M. Nódulos dolorosos en muslos. Actas Dermosifiliogr. 2021;112:357–358.</p>" ] ] "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 580 "Ancho" => 600 "Tamanyo" => 37807 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image.</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 900 "Ancho" => 900 "Tamanyo" => 273933 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histology. A. Hematoxylin-eosin, original magnification, ×10. B and C. Hematoxylin-eosin, original magnification, ×40.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cold-Associated Perniosis of the Thighs (“Equestrian-Type” Chilblain): A Reappraisal Based on a Clinicopathologic and Immunohistochemical Study of 6 Cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G. Ferrara" 1 => "L. Cerroni" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0000000000000477" "Revista" => array:7 [ "tituloSerie" => "Am J Dermatopathol." "fecha" => "2016" "volumen" => "38" "paginaInicial" => "726" "paginaFinal" => "731" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26885604" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S030228381200629X" "estado" => "S300" "issn" => "03022838" ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Equestrian cold panniculitis in women" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "B.E. Beacham" 1 => "P.H. Cooper" 2 => "C.S. Buchanan" 3 => "P.E. Weary" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Dermatol." "fecha" => "1980" "volumen" => "116" "paginaInicial" => "1025" "paginaFinal" => "1027" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7191239" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0302283812014248" "estado" => "S300" "issn" => "03022838" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tobogganers thighs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.C. Long" 1 => "P.J. Holt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2230.1992.tb00264.x" "Revista" => array:7 [ "tituloSerie" => "Clin Exp Dermatol." "fecha" => "1992" "volumen" => "17" "paginaInicial" => "466" "paginaFinal" => "467" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1486722" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0302283809009300" "estado" => "S300" "issn" => "03022838" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pernio of the hips in young girls wearing tight-fitting jeans with a low waistband" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K. Weismann" 1 => "F.G. Larsen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2340/00015555-0151" "Revista" => array:6 [ "tituloSerie" => "Acta Derm Venereol." "fecha" => "2006" "volumen" => "86" "paginaInicial" => "558" "paginaFinal" => "559" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17106612" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ice-pack dermatosis: a cold-induced dermatitis with similarities to cold panniculitis and perniosis that histopathologically resembles lupus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.E. West" 1 => "T.H. McCalmont" 2 => "J.P. North" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/jamadermatol.2013.6302" "Revista" => array:7 [ "tituloSerie" => "JAMA Dermatol." "fecha" => "2013" "volumen" => "149" "paginaInicial" => "1314" "paginaFinal" => "1318" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24026341" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0302283810005403" "estado" => "S300" "issn" => "03022838" ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Equestrian perniosis: a report of 2 cases and a review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C.L. Stewart" 1 => "D.J. Adler" 2 => "A. Jacobson" 3 => "B.A. Brod" 4 => "M.M. Shinohara" 5 => "J.T. Seykora" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e31824c221f" "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol." "fecha" => "2013" "volumen" => "35" "paginaInicial" => "237" "paginaFinal" => "240" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22534636" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cold-associated perniosis of the thighs histopathologically mimicking lupus. Six observations" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R. Karkouche" 1 => "C. Bernigaud" 2 => "J. Fontugne" 3 => "O. Zehou" 4 => "G. Bellaud" 5 => "M. N’Diaye" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/jdv.13969" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol." "fecha" => "2017" "volumen" => "31" "paginaInicial" => "1029" "paginaFinal" => "1032" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27633611" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Equestrian perniosis associated with cold agglutinins: a novel finding" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B.D. De Silva" 1 => "K. McLaren" 2 => "V.R. Doherty" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1365-2230.2000.00643.x" "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol." "fecha" => "2000" "volumen" => "25" "paginaInicial" => "285" "paginaFinal" => "288" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10971486" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perniosis/cold panniculitis in French equestrians: four cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N. Kluger" 1 => "L. Marty" 2 => "C. Bourseau-Quetier" 3 => "M. Blum" 4 => "M. Camus" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/ijd.13360" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol." "fecha" => "2016" "volumen" => "55" "paginaInicial" => "e618" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27419657" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000011200000004/v1_202104020837/S1578219021000524/v1_202104020837/en/main.assets" "Apartado" => array:4 [ "identificador" => "6154" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case for Diagnosis" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000004/v1_202104020837/S1578219021000524/v1_202104020837/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000524?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 11 | 7 | 18 |
| 2024 Octubre | 122 | 57 | 179 |
| 2024 Septiembre | 109 | 39 | 148 |
| 2024 Agosto | 155 | 63 | 218 |
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| 2024 Marzo | 102 | 29 | 131 |
| 2024 Febrero | 99 | 41 | 140 |
| 2024 Enero | 95 | 44 | 139 |
| 2023 Diciembre | 108 | 19 | 127 |
| 2023 Noviembre | 114 | 38 | 152 |
| 2023 Octubre | 81 | 20 | 101 |
| 2023 Septiembre | 80 | 27 | 107 |
| 2023 Agosto | 75 | 28 | 103 |
| 2023 Julio | 116 | 36 | 152 |
| 2023 Junio | 70 | 27 | 97 |
| 2023 Mayo | 91 | 31 | 122 |
| 2023 Abril | 69 | 23 | 92 |
| 2023 Marzo | 94 | 36 | 130 |
| 2023 Febrero | 107 | 30 | 137 |
| 2023 Enero | 70 | 36 | 106 |
| 2022 Diciembre | 85 | 59 | 144 |
| 2022 Noviembre | 66 | 39 | 105 |
| 2022 Octubre | 40 | 22 | 62 |
| 2022 Septiembre | 39 | 29 | 68 |
| 2022 Agosto | 45 | 37 | 82 |
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| 2022 Junio | 61 | 29 | 90 |
| 2022 Mayo | 94 | 48 | 142 |
| 2022 Abril | 110 | 40 | 150 |
| 2022 Marzo | 83 | 65 | 148 |
| 2022 Febrero | 88 | 36 | 124 |
| 2022 Enero | 92 | 44 | 136 |
| 2021 Diciembre | 61 | 48 | 109 |
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| 2021 Octubre | 55 | 75 | 130 |
| 2021 Septiembre | 47 | 60 | 107 |
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