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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 14-year-old boy presented with oval-shaped patches of hypopigmented alopecia and hypoesthesia on the back&#44; legs&#44; and forearms&#44; which had appeared 9 months earlier &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; Tests ordered included a complete blood count&#44; biochemistry&#44; antinuclear antibodies&#44; immunoglobulin&#44; and protein electrophoresis in addition to a Mantoux test and serology for syphilis&#44; HIV&#44; hepatitis B virus&#44; and hepatitis C virus&#46; All test results were normal or negative&#46; Polymerase chain reaction &#40;PCR&#41; on a skin biopsy sample was negative for <span class="elsevierStyleItalic">Mycobacterium leprae</span>&#46; Histologic findings included a chronic but moderate lymphocytic inflammatory infiltrate without atypia in a panfollicular and folliculocentric distribution&#44; with discrete spongiosis and no lichenoid damage &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; Colloidal iron staining revealed a slight mucin layer in the follicular epithelium&#46; The lymphocytic infiltrate was composed almost entirely of T cells&#46; Immunostaining was diffuse for CD4&#44; CD3&#44; CD5&#44; and CD8 and focal for CD20&#46; No monoclonal rearrangement was detected &#40;after PCR&#41; for the T-cell receptor gene&#46; The lesions resolved spontaneously&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Some authors consider mucin-poor follicular mucinosis&#8212;also known as folliculotropic T-cell lymphocytosis&#8212;to be a variant of cutaneous lymphoid dyscrasia with a low risk of progression to cutaneous T-cell lymphoma&#46; As happened in our case&#44; hypoesthesia or dysesthesia is not an uncommon finding in mucinous alopecia lesions&#46; The cause of hypoesthesia in mucinous alopecia is unclear&#44; but it is thought that much of the cutaneous innervation is associated with the hair follicle and surrounding vascularization&#46; When these structures are severely affected&#44; sensitivity is altered&#46; In cases like this one&#44; the principal differential diagnosis is the folliculotropic variant of hypopigmented mycosis fungoides&#46;</p></span>"
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e-Images in Dermatology
Alopecia and Hypoesthesia in Folliculotropic T-Cell Lymphocytosis
Alopecia e hipoestesia en linfocitosis de células T foliculotrópica
B. Monteagudoa,
Autor para correspondencia
, J.Á. Vázquez-Buenob, E. León-Muiñosc
a Servicio de Dermatología, Complejo Hospitalario Universitario de Ferrol, SERGAS, Ferrol, A Coruña, Spain
b Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Ferrol, SERGAS, Ferrol, A Coruña, Spain
c Pediatría, Centro de Salud de San Sadurniño, SERGAS, San Sadurniño, A Coruña, Spain
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