Case for Diagnosis
Tumors Distributed Linearly Near the Scapula in a Young Man
Tumoraciones con distribución lineal en la región escapular de un varón joven
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"apellidos" => "Pérez-Hortet" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731019301243" "doi" => "10.1016/j.ad.2018.08.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301243?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019302483?idApp=UINPBA000044" "url" => "/15782190/0000011000000008/v1_201910050935/S1578219019302483/v1_201910050935/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219019302239" "issn" => "15782190" "doi" => "10.1016/j.adengl.2019.07.004" "estado" => "S300" "fechaPublicacion" => "2019-10-01" "aid" => "2124" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2019;110:681-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Practical Dermoscopy</span>" "titulo" => "A Shiny Nodule on the Forehead of a Man" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "681" "paginaFinal" => "682" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Nódulo brillante en la frente de un adulto" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 579 "Ancho" => 755 "Tamanyo" => 80625 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Tumor that first appeared 4 months previously on the hairline of an adult.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.F. 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Morales-Conde, J. Raya-Maldonado, B. García-Bravo, J.J. Ríos-Martin" "autores" => array:4 [ 0 => array:4 [ "nombre" => "M." "apellidos" => "Morales-Conde" "email" => array:1 [ 0 => "macarena.moralesconde@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Raya-Maldonado" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "B." "apellidos" => "García-Bravo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "J.J." "apellidos" => "Ríos-Martin" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Gestión Clínica de Dermatología, Hospital Universitario Virgen Macarena, Sevilla, España" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Unidad de Gestión Clínica de Anatomía Patológica, Hospital Universitario Virgen Macarena, Sevilla, España" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tumoraciones con distribución lineal en la región escapular de un varón joven" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 680 "Ancho" => 905 "Tamanyo" => 95441 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Clinical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 22-year-old man consulted the dermatology department with a lesion on his right scapula. The lesion had been present since birth, was sometimes painful, and bled with friction. He reported that the lesion had been treated with cryotherapy when he was an adolescent. Nevertheless, the lesion persisted and had gradually increased in size.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">The lesion comprised several papules and tumors arranged linearly on the right scapula. These were pink, differed in size between 0.5 and 3<span class="elsevierStyleHsp" style=""></span>cm in diameter, and had a pedunculated base. The spherical parts were covered with smooth, shiny skin, and many had a marked layer of yellowish, blackish hyperkeratosis that was spiked and crateriform in appearance (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The whole lesion measured 9.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>3<span class="elsevierStyleHsp" style=""></span>cm.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Histopathology</span><p id="par0015" class="elsevierStylePara elsevierViewall">Histopathology revealed numerous cystic lesions that were invaginated from the epidermis and several exophytic papillomatous lesions covered by squamous epithelium with hyperkeratosis. The deepest area comprised a double-layered epithelium (the internal layer formed by cylindrical cells and the external layer formed by cuboidal myoepithelial cells). The underlying stroma was rich in plasma cells (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">What is your diagnosis?</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Congenital linear syringocystadenoma papilliferum.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Course and Treatment</span><p id="par0030" class="elsevierStylePara elsevierViewall">Given that the lesion was causing the patient some discomfort, we removed it surgically using shave excision and electrocoagulation. No recurrences have been observed in the last 2 years.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Comment</span><p id="par0035" class="elsevierStylePara elsevierViewall">Syringocystadenoma papilliferum is an uncommon benign hamartomatous adnexal tumor.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> While its pathogenesis remains unclear, it is thought to result from pluripotent cells with eccrine differentiation and, more frequently, apocrine differentiation.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">The tumor typically affects children and adolescents; in fact, it is congenital in half of all cases.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> Clinical presentation is variable, ranging from a solitary papule (the most common manifestation) to several nodules arranged linearly, as in the present case, and often with a hyperkeratotic center. During adolescence, it tends to increase in size and become more verrucous.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">The most common locations are the scalp, face, and neck (75%).<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> Less common sites include the abdomen, arm, axilla, breast, back, buttock, and vulva. The lesion has been reported on the back in only 4 cases.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Syringocystadenoma papilliferum may appear alongside other benign adnexal tumors, such as tubular apocrine adenoma, hidradenoma papilliferum, and trichoblastoma.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> In 30% of cases, the tumor originates within a nevus sebaceus of Jadassohn.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> Basal cell carcinoma has been reported in 10% of cases. Other, more unusual associated malignant neoplasms include squamous cell carcinoma and syringocystadenocarcinoma papilliferum.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> Ulceration and/or rapid growth are indicative of malignant transformation.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The differential diagnosis should include basal cell carcinoma, squamous cell carcinoma, and cysts.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> Diagnosis must be confirmed by biopsy. Hematoxylin-eosin staining reveals epithelial projections toward the dermis with tubular structures that connect to the surface and are composed of a double layer of cells: the external layer comprises cuboidal cells and the internal layer cylindrical cells. The stroma is rich in plasma cells.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">Treatment is based on surgical excision, although CO<span class="elsevierStyleInf">2</span> laser treatment is a good alternative when the location makes surgery difficult.</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflicts of Interest</span><p id="par0065" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:8 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Clinical History" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Physical Examination" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Histopathology" ] 3 => array:2 [ "identificador" => "sec0020" "titulo" => "Diagnosis" ] 4 => array:2 [ "identificador" => "sec0025" "titulo" => "Course and Treatment" ] 5 => array:2 [ "identificador" => "sec0030" "titulo" => "Comment" ] 6 => array:2 [ "identificador" => "sec0035" "titulo" => "Conflicts of Interest" ] 7 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2018-01-24" "fechaAceptado" => "2018-04-08" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Morales-Conde M, Raya-Maldonado J, García-Bravo B, Ríos-Martin JJ. Tumoraciones con distribución lineal en la región escapular de un varón joven. Actas Dermosifiliogr. 2019;110:683–684.</p>" ] ] "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 680 "Ancho" => 905 "Tamanyo" => 95441 ] ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 680 "Ancho" => 905 "Tamanyo" => 256944 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin staining in both histology images.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A case of syringocystadenoma papilliferum of eyelid with literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. 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Maiti" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0378-6323.90978" "Revista" => array:5 [ "tituloSerie" => "Indian J Dermatol Venereol Leprol" "fecha" => "2012" "volumen" => "78" "paginaInicial" => "123" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22199090" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000011000000008/v1_201910050935/S1578219019302252/v1_201910050935/en/main.assets" "Apartado" => array:4 [ "identificador" => "6154" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case for Diagnosis" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000008/v1_201910050935/S1578219019302252/v1_201910050935/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019302252?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 10 | 7 | 17 |
| 2024 Octubre | 69 | 58 | 127 |
| 2024 Septiembre | 69 | 31 | 100 |
| 2024 Agosto | 98 | 57 | 155 |
| 2024 Julio | 88 | 40 | 128 |
| 2024 Junio | 85 | 35 | 120 |
| 2024 Mayo | 71 | 30 | 101 |
| 2024 Abril | 69 | 32 | 101 |
| 2024 Marzo | 67 | 28 | 95 |
| 2024 Febrero | 57 | 33 | 90 |
| 2024 Enero | 58 | 30 | 88 |
| 2023 Diciembre | 55 | 22 | 77 |
| 2023 Noviembre | 57 | 31 | 88 |
| 2023 Octubre | 54 | 27 | 81 |
| 2023 Septiembre | 47 | 38 | 85 |
| 2023 Agosto | 29 | 20 | 49 |
| 2023 Julio | 33 | 34 | 67 |
| 2023 Junio | 35 | 24 | 59 |
| 2023 Mayo | 39 | 17 | 56 |
| 2023 Abril | 27 | 32 | 59 |
| 2023 Marzo | 45 | 33 | 78 |
| 2023 Febrero | 40 | 26 | 66 |
| 2023 Enero | 34 | 31 | 65 |
| 2022 Diciembre | 42 | 45 | 87 |
| 2022 Noviembre | 32 | 30 | 62 |
| 2022 Octubre | 26 | 20 | 46 |
| 2022 Septiembre | 23 | 43 | 66 |
| 2022 Agosto | 46 | 41 | 87 |
| 2022 Julio | 23 | 46 | 69 |
| 2022 Junio | 15 | 26 | 41 |
| 2022 Mayo | 30 | 44 | 74 |
| 2022 Abril | 36 | 27 | 63 |
| 2022 Marzo | 42 | 58 | 100 |
| 2022 Febrero | 31 | 34 | 65 |
| 2022 Enero | 44 | 50 | 94 |
| 2021 Diciembre | 28 | 49 | 77 |
| 2021 Noviembre | 34 | 38 | 72 |
| 2021 Octubre | 41 | 46 | 87 |
| 2021 Septiembre | 28 | 34 | 62 |
| 2021 Agosto | 20 | 29 | 49 |
| 2021 Julio | 14 | 11 | 25 |
| 2021 Junio | 13 | 21 | 34 |
| 2021 Mayo | 23 | 34 | 57 |
| 2021 Abril | 51 | 65 | 116 |
| 2021 Marzo | 34 | 27 | 61 |
| 2021 Febrero | 34 | 24 | 58 |
| 2021 Enero | 18 | 19 | 37 |
| 2020 Diciembre | 22 | 16 | 38 |
| 2020 Noviembre | 11 | 22 | 33 |
| 2020 Octubre | 14 | 14 | 28 |
| 2020 Septiembre | 14 | 9 | 23 |
| 2020 Agosto | 19 | 20 | 39 |
| 2020 Julio | 8 | 11 | 19 |
| 2020 Junio | 22 | 14 | 36 |
| 2020 Mayo | 7 | 6 | 13 |
| 2020 Abril | 11 | 8 | 19 |
| 2020 Marzo | 16 | 7 | 23 |
| 2020 Febrero | 3 | 2 | 5 |
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