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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 38-year-old man presented with a waxy congenital plaque on his forehead that had undergone changes in the past few years&#46; These changes included the development of several bluish nodules within the plaque&#46; The texture of these nodules had also varied&#46; Physical examination showed a well-delimited yellowish plaque measuring 3<span class="elsevierStyleHsp" style=""></span>cm containing 2 blue nodules and surrounded by several warty&#44; papillomatous areas &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Dermoscopic examination showed a white-yellowish cobblestone pattern with 2 large&#44; asymmetric blue-gray ovoid nests&#44; the largest of which contained thick vessels&#46; It also showed a symmetric erythematous lesion with exophytic papillary structures and polymorphous &#40;dotted and linear&#41; vessels &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; The histologic images are shown in <a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Diagnosis&#58; Collision tumors or tumors composed of trichoblastoma and syringocystadenoma papilliferum on a sebaceous nevus&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Sebaceous nevus is a benign congenital hamartoma that usually affects the scalp or face&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> It is well known that secondary tumors with a predominant line of differentiation &#40;follicular&#44; sebaceous&#44; or apocrine&#41; can arise in sebaceous nevi&#46; These tumors are observed in approximately 10&#37; to 20&#37; of cases&#46; The 2 main secondary tumors associated with sebaceous nevus are trichoblastoma and syringocystadenocarcinoma papilliferum&#44; which are generally benign&#46; Malignant tumors can also develop but they are rare&#46; The most common type is basal cell carcinoma&#46; Few studies have described the dermoscopic features of lesions arising in sebaceous nevus&#46; Zaballos et al&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> described the main characteristics of these tumors in a review of 58 cases&#46; Basal cell carcinomas tend to appear as large&#44; blue-gray&#44; asymmetric ovoid nests possibly containing blue-gray globules&#46; Trichoblastomas&#44; by contrast&#44; tend to have more symmetric&#44; homogeneous ovoid nests occupying the entire lesion&#46; Basal cell carcinomas tend to start with characteristic arborizing telangiectasias&#46; Trichoblastoma overlying a sebaceous nevus has also been described as an irregular blue-gray area with a linear vascular pattern or arborizing telangiectasias with white structures&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> Syringocystadenocarcinoma papilliferum shows a symmetric pattern formed by an exophytic papillary structure with erythema&#44; ulceration&#44; and atypical vessels &#40;coma&#44; hairpin&#44; horseshoe-shaped&#44; and atypical irregular&#44; glomerular&#44; dotted&#44; and polymorphous&#41; vessels&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> On occasions&#44; this erythematous background may be divided by whitish linear structures that demarcate lobules containing different types of vessels&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> Apocrine hidrocystomas appear as symmetric homogeneous areas with arborizing telangiectasias&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Dermoscopy is one of the most accurate in vivo tools available for guiding diagnosis prior to surgery&#46; It is also useful for monitoring disease progression and enabling the early detection of tumors arising in sebaceous nevi&#46; More descriptive studies of the characteristics of these tumors are needed to aid diagnosis&#46; Histologic examination&#44; however&#44; provides the greatest accuracy and is the gold standard diagnostic tool&#44; as the entities can sometimes mimic each other on dermoscopy&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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Practical Dermoscopy
Tumor Collision Over Sebaceous Nevus: Clues for Dermoscopic Diagnosis
Tumores de colisión sobre nevus sebáceo: claves para su diagnóstico dermatoscópico
A. Lobato-Berezoa,b,
Autor para correspondencia
allobe@hotmail.es

Corresponding author.
, P. Aguilera-Peiróc, R.M. Pujola
a Unidad de Dermatología, Hospital del Mar, Barcelona, España
b Unidad de Dermatología, Hospital Universitari General de Catalunya, Sant Cugat del Vallès, Barcelona, España
c Unidad de Dermatología, Hospital Clinic Barcelona, Barcelona, España
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        "titulo" => "Tumores de colisi&#243;n sobre nevus seb&#225;ceo&#58; claves para su diagn&#243;stico dermatosc&#243;pico"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Two large asymmetric blue-gray ovoid nests&#44; one containing thick vessels and a symmetric erythematous lesion with exophytic papillary structures and dotted and linear vessels in the interior&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 38-year-old man presented with a waxy congenital plaque on his forehead that had undergone changes in the past few years&#46; These changes included the development of several bluish nodules within the plaque&#46; The texture of these nodules had also varied&#46; Physical examination showed a well-delimited yellowish plaque measuring 3<span class="elsevierStyleHsp" style=""></span>cm containing 2 blue nodules and surrounded by several warty&#44; papillomatous areas &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Dermoscopic examination showed a white-yellowish cobblestone pattern with 2 large&#44; asymmetric blue-gray ovoid nests&#44; the largest of which contained thick vessels&#46; It also showed a symmetric erythematous lesion with exophytic papillary structures and polymorphous &#40;dotted and linear&#41; vessels &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; The histologic images are shown in <a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Diagnosis&#58; Collision tumors or tumors composed of trichoblastoma and syringocystadenoma papilliferum on a sebaceous nevus&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Sebaceous nevus is a benign congenital hamartoma that usually affects the scalp or face&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> It is well known that secondary tumors with a predominant line of differentiation &#40;follicular&#44; sebaceous&#44; or apocrine&#41; can arise in sebaceous nevi&#46; These tumors are observed in approximately 10&#37; to 20&#37; of cases&#46; The 2 main secondary tumors associated with sebaceous nevus are trichoblastoma and syringocystadenocarcinoma papilliferum&#44; which are generally benign&#46; Malignant tumors can also develop but they are rare&#46; The most common type is basal cell carcinoma&#46; Few studies have described the dermoscopic features of lesions arising in sebaceous nevus&#46; Zaballos et al&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> described the main characteristics of these tumors in a review of 58 cases&#46; Basal cell carcinomas tend to appear as large&#44; blue-gray&#44; asymmetric ovoid nests possibly containing blue-gray globules&#46; Trichoblastomas&#44; by contrast&#44; tend to have more symmetric&#44; homogeneous ovoid nests occupying the entire lesion&#46; Basal cell carcinomas tend to start with characteristic arborizing telangiectasias&#46; Trichoblastoma overlying a sebaceous nevus has also been described as an irregular blue-gray area with a linear vascular pattern or arborizing telangiectasias with white structures&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> Syringocystadenocarcinoma papilliferum shows a symmetric pattern formed by an exophytic papillary structure with erythema&#44; ulceration&#44; and atypical vessels &#40;coma&#44; hairpin&#44; horseshoe-shaped&#44; and atypical irregular&#44; glomerular&#44; dotted&#44; and polymorphous&#41; vessels&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> On occasions&#44; this erythematous background may be divided by whitish linear structures that demarcate lobules containing different types of vessels&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> Apocrine hidrocystomas appear as symmetric homogeneous areas with arborizing telangiectasias&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Dermoscopy is one of the most accurate in vivo tools available for guiding diagnosis prior to surgery&#46; It is also useful for monitoring disease progression and enabling the early detection of tumors arising in sebaceous nevi&#46; More descriptive studies of the characteristics of these tumors are needed to aid diagnosis&#46; Histologic examination&#44; however&#44; provides the greatest accuracy and is the gold standard diagnostic tool&#44; as the entities can sometimes mimic each other on dermoscopy&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Lobato-Berezo A&#44; Aguilera-Peir&#243; P&#44; Pujol RM&#46; Tumores de colisi&#243;n sobre nevus seb&#225;ceo&#58; claves para su diagn&#243;stico dermatosc&#243;pico&#46; Actas Dermosifiliogr&#46; 2018&#59;109&#58;647&#8211;648&#46;</p>"
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Trichoblastoma and syringocystoadenoma papilliferum in a sebecaeous nevus &#40;numerous structures similar to follicle germinal cells with cystic invaginations composed of 2 layers of epithelial cells &#40;hematoxylin and eosin&#44; original magnification &#215;10&#41;&#46;</p>"
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