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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Dermatopathic lymphadenopathy is a well-defined histopathologic entity with an underestimated prevalence in the general population&#46; It is characterized by lymph node enlargement secondary to a typically pruritic skin disorder&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> It is a form of paracortical hyperplasia that usually occurs in chronic skin diseases&#44; but it can also be found in disorders in which the skin is not involved&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> In most cases&#44; dermatopathic lymphadenopathy clinically manifests as enlargement of the peripheral lymph nodes&#44; although normal-sized nodes may also be seen&#46; It should be contemplated alongside malignant&#44; infectious&#44; and other diseases in the differential diagnosis of peripheral lymphadenopathy&#46; It is widely known that a palpable lymph node is a clinical sign and risk marker of a solid or lymphoproliferative tumor&#44;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> and it is therefore essential to establish a diagnosis and monitor patients with this finding&#46; When attending a patient with a chronic skin disorder who presents with enlarged lymph nodes&#44; it is important to consider a broad differential diagnosis that includes autoimmune diseases&#44;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> infections&#44; and tumors&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">We performed a retrospective analysis of clinically diagnosed and histologically confirmed cases of dermatopathic lymphadenopathy cases at our unit between January 2011 and December 2016&#46; We included 4 patients&#44; whose characteristics are summarized in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; The main diagnosis for which they were under follow-up was atopic dermatitis and there was also an isolated case of lepromatous leprosy&#46; The atopic patients had a Scoring Atopic Dermatitis &#40;SCORAD&#41; index score of over 40 at the time of diagnostic confirmation&#46; They also all had active skin lesions&#46; Palpable lymph nodes had been identified in different locations during the physical examination&#46; They were mostly located in the axillary&#44; groin&#44; and neck regions&#44; which were investigated by ultrasound and&#47;or computed tomography &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Depending on their accessibility&#44; the nodes were sampled by biopsy or fine-needle aspiration &#40;FNA&#41; &#40;<a class="elsevierStyleCrossRefs" href="#fig0010">Figs&#46; 2 and 3</a>&#41;&#46; Follow-up duration ranged from 6 months to 5 years&#46; The lymph nodes disappeared in 3 of the 4 patients and reduced considerably in size in the fourth&#44; whose atopic dermatitis is currently being treated with combined oral corticosteroid and intravenous immunoglobulin therapy&#46; None of the patients have presented any signs of malignancy&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Dermatopathic lymphadenopathy is a benign entity with characteristic histologic features that is frequently seen in patients with inflammatory skin disease&#46; It was first described by Pautrier and Woringer in 1937&#44; but the term <span class="elsevierStyleItalic">dermatopathic lymphadenopathy</span> did not appear until 1942&#44; when it was coined by Hurwitt&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">5</span></a> Dermatopathic lymphadenopathy should always be contemplated in patients with persistent lymph node enlargement&#46; It can accompany different types of chronic skin disorders and is more common in patients with extensive skin involvement&#46; Lymph node enlargement tends to be asymptomatic and mainly affects inguinal&#44; axillary&#44; and cervical nodes&#46; The lymph nodes tend to be mobile and not attached to underlying structures&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The characteristic histologic findings include slightly expanded germinal centers surrounded by lymphocytes and a widened paracortical area&#46; The follicular pattern is retained&#46; The most characteristic finding is an expanded paracortical area and pale staining due to the presence of Langerhans cells and in particular interdigitating dendritic cells&#46; Macrophages are a minor component&#44; but they are characteristic because they contain cytoplasmic pigment&#59; most of the cells contain melanin but a small proportion contain hemosiderin&#46; Pigment deposits may also be observed in tattoos&#44; nodal nevus cell inclusions&#44; and melanoma metatasases&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">6</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">A broad differential diagnosis must be considered in the case of persistent lymph node enlargement&#46; Dermatopathic lymphadenopathy occurs in association with a variety of skin disorders ranging from infections&#44; such as tuberculosis or fungal infections&#44; to erythrodermas&#44; such as psoriatic or atopic erythrodermas &#40;like the cases in our series&#41;&#46; Other disorders include sarcoidosis&#44; lymphoproliferative disorders&#44; tumor metastases&#44;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a> and infections &#40;e&#46;g&#46;&#44; human immunodeficiency virus infection&#44; tuberculosis&#44; and toxoplasmosis&#41;&#46; Dermatopathic lymphadenopathy may also been seen in exfoliative or eczematous diseases&#44; such as toxic shock syndrome&#44; pemphigus&#44; neurodermatitis&#44; and atrophia cutis senilis&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a> Prognosis is worse when there is associated mycosis fungoides&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The first step in the diagnostic workup is nodal sampling by FNA and&#47;or biopsy&#46; Prior imaging can help identify the extent of disease and select the most appropriate node for biopsy&#46; Considering its increasing use as a diagnostic tool in dermatology&#44; cutaneous ultrasound should also be considered&#46; Inflammatory lymph nodes tend to have an ellipsoid shape with a length to width ratio of over 2&#44; and unlike nodes that are suggestive of tumor infiltration&#44; they tend to have intact corticohilar differentiation&#46; Considering the risk of lymphoproliferative disease&#44; particularly in patients with atopic dermatitis&#44; close follow-up is recommended in the absence of an objective clinical diagnosis&#46; Histologically&#44; dermatopathic lymphadenopathy should be differentiated from Hodgkin lymphoma and enlarged lymph nodes associated with T-cell lymphoma&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Follow-up is essential&#46; Dermatopathic lymphadenopathy is not only more common in patients with atopic dermatitis&#44; but is also a risk factor for subsequent lymphomas&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Bueno-Rodriguez A&#44; Ruiz-Villaverde R&#44; Caba-Molina M&#44; Tercedor-S&#225;nchez J&#46; Linfadenopat&#237;a dermop&#225;tica&#58; &#191;realizamos una correcta aproximaci&#243;n diagn&#243;stica&#63; Actas Dermosifiliogr&#46; 2018&#59;109&#58;361&#8211;363&#46;</p>"
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Patient 4&#46; Computed tomography scan of chest and abdomen&#58; enlarged bilateral axillary lymph nodes with a diameter of up to 13&#46;7<span class="elsevierStyleHsp" style=""></span>mm at the narrowest point on both sides&#46;</p>"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Patient 4 &#40;hematoxylin-eosin original&#44; original magnification &#215;5&#41;&#58; lymph node with preserved architecture presenting hyperplasia of lymphoid follicles in the cortex with pale staining in paracortical area&#46;</p>"
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Patient 4 &#40;CD1A<span class="elsevierStyleHsp" style=""></span>&#215;10&#41;&#44; original magnification&#46; Note the paracortical hyperplasia composed of Langerhans cells&#46;</p>"
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          "leyenda" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Abbreviations&#58; CT&#44; computed tomography&#59; FNA&#44; fine-needle aspiration&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diagnosis&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atopic dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atopic dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Location&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cervical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Axillary&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Age&#44; y&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">56&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Imaging study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">CT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Ultrasound&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Ultrasound&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">CT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Histopathologic study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">FNA&#47;biopsy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">FNA&#47;biopsy&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Yes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Time to resolution&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 mo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 mo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 mo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Persistence &#40;&#62;&#160;12 mo&#41;&nbsp;\t\t\t\t\t\t\n
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          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Clinical&#44; Imaging&#44; and Histologic Characteristics of 4 Patients With Dermatopathic lymphadenopathy&#46;</p>"
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Case and Research Letters
Dermatopathic Lymphadenopathy: Is Our Diagnostic Approach Correct?
Linfadenopatía dermopática: ¿realizamos una correcta aproximación diagnóstica?
A. Bueno-Rodrigueza, R. Ruiz-Villaverdea,
Autor para correspondencia
ismenios@hotmail.com

Corresponding author.
, M. Caba-Molinab, J. Tercedor-Sáncheza
a Unidad de Dermatología, Complejo Hospitalario de Granada, Granada, España
b Unidad de Anatomía Patológica, Complejo Hospitalario de Granada, Granada, España
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It is widely known that a palpable lymph node is a clinical sign and risk marker of a solid or lymphoproliferative tumor&#44;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> and it is therefore essential to establish a diagnosis and monitor patients with this finding&#46; When attending a patient with a chronic skin disorder who presents with enlarged lymph nodes&#44; it is important to consider a broad differential diagnosis that includes autoimmune diseases&#44;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> infections&#44; and tumors&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">We performed a retrospective analysis of clinically diagnosed and histologically confirmed cases of dermatopathic lymphadenopathy cases at our unit between January 2011 and December 2016&#46; We included 4 patients&#44; whose characteristics are summarized in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; The main diagnosis for which they were under follow-up was atopic dermatitis and there was also an isolated case of lepromatous leprosy&#46; The atopic patients had a Scoring Atopic Dermatitis &#40;SCORAD&#41; index score of over 40 at the time of diagnostic confirmation&#46; They also all had active skin lesions&#46; Palpable lymph nodes had been identified in different locations during the physical examination&#46; They were mostly located in the axillary&#44; groin&#44; and neck regions&#44; which were investigated by ultrasound and&#47;or computed tomography &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Depending on their accessibility&#44; the nodes were sampled by biopsy or fine-needle aspiration &#40;FNA&#41; &#40;<a class="elsevierStyleCrossRefs" href="#fig0010">Figs&#46; 2 and 3</a>&#41;&#46; Follow-up duration ranged from 6 months to 5 years&#46; The lymph nodes disappeared in 3 of the 4 patients and reduced considerably in size in the fourth&#44; whose atopic dermatitis is currently being treated with combined oral corticosteroid and intravenous immunoglobulin therapy&#46; None of the patients have presented any signs of malignancy&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Dermatopathic lymphadenopathy is a benign entity with characteristic histologic features that is frequently seen in patients with inflammatory skin disease&#46; It was first described by Pautrier and Woringer in 1937&#44; but the term <span class="elsevierStyleItalic">dermatopathic lymphadenopathy</span> did not appear until 1942&#44; when it was coined by Hurwitt&#46;<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">5</span></a> Dermatopathic lymphadenopathy should always be contemplated in patients with persistent lymph node enlargement&#46; It can accompany different types of chronic skin disorders and is more common in patients with extensive skin involvement&#46; Lymph node enlargement tends to be asymptomatic and mainly affects inguinal&#44; axillary&#44; and cervical nodes&#46; The lymph nodes tend to be mobile and not attached to underlying structures&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The characteristic histologic findings include slightly expanded germinal centers surrounded by lymphocytes and a widened paracortical area&#46; The follicular pattern is retained&#46; The most characteristic finding is an expanded paracortical area and pale staining due to the presence of Langerhans cells and in particular interdigitating dendritic cells&#46; Macrophages are a minor component&#44; but they are characteristic because they contain cytoplasmic pigment&#59; most of the cells contain melanin but a small proportion contain hemosiderin&#46; Pigment deposits may also be observed in tattoos&#44; nodal nevus cell inclusions&#44; and melanoma metatasases&#46;<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">6</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">A broad differential diagnosis must be considered in the case of persistent lymph node enlargement&#46; Dermatopathic lymphadenopathy occurs in association with a variety of skin disorders ranging from infections&#44; such as tuberculosis or fungal infections&#44; to erythrodermas&#44; such as psoriatic or atopic erythrodermas &#40;like the cases in our series&#41;&#46; Other disorders include sarcoidosis&#44; lymphoproliferative disorders&#44; tumor metastases&#44;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a> and infections &#40;e&#46;g&#46;&#44; human immunodeficiency virus infection&#44; tuberculosis&#44; and toxoplasmosis&#41;&#46; Dermatopathic lymphadenopathy may also been seen in exfoliative or eczematous diseases&#44; such as toxic shock syndrome&#44; pemphigus&#44; neurodermatitis&#44; and atrophia cutis senilis&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a> Prognosis is worse when there is associated mycosis fungoides&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The first step in the diagnostic workup is nodal sampling by FNA and&#47;or biopsy&#46; Prior imaging can help identify the extent of disease and select the most appropriate node for biopsy&#46; Considering its increasing use as a diagnostic tool in dermatology&#44; cutaneous ultrasound should also be considered&#46; Inflammatory lymph nodes tend to have an ellipsoid shape with a length to width ratio of over 2&#44; and unlike nodes that are suggestive of tumor infiltration&#44; they tend to have intact corticohilar differentiation&#46; Considering the risk of lymphoproliferative disease&#44; particularly in patients with atopic dermatitis&#44; close follow-up is recommended in the absence of an objective clinical diagnosis&#46; Histologically&#44; dermatopathic lymphadenopathy should be differentiated from Hodgkin lymphoma and enlarged lymph nodes associated with T-cell lymphoma&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">Follow-up is essential&#46; Dermatopathic lymphadenopathy is not only more common in patients with atopic dermatitis&#44; but is also a risk factor for subsequent lymphomas&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Bueno-Rodriguez A&#44; Ruiz-Villaverde R&#44; Caba-Molina M&#44; Tercedor-S&#225;nchez J&#46; Linfadenopat&#237;a dermop&#225;tica&#58; &#191;realizamos una correcta aproximaci&#243;n diagn&#243;stica&#63; Actas Dermosifiliogr&#46; 2018&#59;109&#58;361&#8211;363&#46;</p>"
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Patient 4&#46; Computed tomography scan of chest and abdomen&#58; enlarged bilateral axillary lymph nodes with a diameter of up to 13&#46;7<span class="elsevierStyleHsp" style=""></span>mm at the narrowest point on both sides&#46;</p>"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Patient 4 &#40;hematoxylin-eosin original&#44; original magnification &#215;5&#41;&#58; lymph node with preserved architecture presenting hyperplasia of lymphoid follicles in the cortex with pale staining in paracortical area&#46;</p>"
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Patient 4 &#40;CD1A<span class="elsevierStyleHsp" style=""></span>&#215;10&#41;&#44; original magnification&#46; Note the paracortical hyperplasia composed of Langerhans cells&#46;</p>"
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          "leyenda" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Abbreviations&#58; CT&#44; computed tomography&#59; FNA&#44; fine-needle aspiration&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Patient 4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diagnosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atopic dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atopic dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atopic dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atopic dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Location&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Inguinal&#47;axillary&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cervical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cervical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Axillary&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Age&#44; y&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">46&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">56&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Imaging study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">CT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Ultrasound&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Ultrasound&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">CT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Histopathologic study&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">FNA&#47;biopsy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">FNA&#47;biopsy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">FNA&#47;biopsy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Biopsy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Surgical&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">No&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Yes&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Time to resolution&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 mo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 mo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">8 mo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Persistence &#40;&#62;&#160;12 mo&#41;&nbsp;\t\t\t\t\t\t\n
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          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Clinical&#44; Imaging&#44; and Histologic Characteristics of 4 Patients With Dermatopathic lymphadenopathy&#46;</p>"
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                            1 => "T&#46; Barnetche"
                            2 => "J&#46; Mazereeuw-Hautier"
                            3 => "N&#46; Meyer"
                            4 => "D&#46; Murrell"
                            5 => "C&#46; Paul"
                          ]
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Información del artículo
ISSN: 15782190
Idioma original: Inglés
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