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thus indicating an association with BSS&#46; <span class="elsevierStyleItalic">CYLD</span> inhibits the tumor necrosis factor &#945; pathway&#44; diminishing expression of nuclear factor &#954;B &#40;NF-&#954;B&#41;&#44; a transcription factor that in turn regulates various antiapoptotic genes involved in the proliferation of adnexa&#46; A loss of the suppressive function of <span class="elsevierStyleItalic">CYLD</span> leads to greater resistance to apoptosis and&#44; consequently&#44; the appearance of these tumors&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#8211;5</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Clinically&#44; cylindromas present as pink nodules on the scalp and behind the ears &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Trichoepitheliomas appear as papules or small translucent or flesh-colored nodules and are located mainly in the center of the face&#44; especially in the nasal region&#46; Spiradenomas&#44; on the other hand&#44; usually present as solitary bluish or flesh-colored nodules that are often painful&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The emotional impact of recurrence of these lesions on the face and scalp makes treatment essential&#46; Our literature search revealed various options&#44; such as electrocautery&#44; dermabrasion&#44; radiofrequency&#44; cryotherapy&#44; CO<span class="elsevierStyleInf">2</span> laser&#44;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> radiotherapy &#40;in special cases&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">7</span></a> and&#44; recently&#44; enucleation&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">8</span></a> The treatment recommended for solitary cylindromas is surgical removal&#44; whereas partial or total skin grafting has been proposed for multiple lesions&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">9</span></a> NF-&#954;B inhibitors&#44; such as acetylsalicylic acid and its derivatives&#44; may prove useful both for prevention and for treatment of cylindromas when applied locally&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> Therefore&#44; treatment should be tailored depending on the patient&#44; size of the lesion&#44; number of lesions&#44; therapeutic options available&#44; and the dermatologist&#39;s experience&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">We report the case of an 80-year-old woman with BSS who presented with multiple cylindromas on the scalp that had recurred since adolescence&#44; together with occasional spiradenomas&#46; Her family history was remarkable in that one of her daughters&#44; aged 49 years&#44; had had numerous facial trichoepitheliomas since puberty&#46; She has been followed regularly in our department for the last 10 years&#44; and several lesions have been removed using elliptical excision and direct closure&#46; Given the high number of lesions and the excisions performed&#44; we sought an alternative that would make for more efficient surgery and benefit the patient by reducing the number of trips to the hospital&#46; Five years ago&#44; we began to perform a technique that combined cytoreduction and subsequent curettage of the growths&#46; Our technique is minimally invasive and efficacious&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">After administration of local anesthetic &#40;mepivacaine 2&#37;&#41;&#44; an incision is made with a scalpel or scissor cut to enable resection of most of the tumor mass and create a portal of entry for the next step&#46; After debulking&#44; the remaining lesional tissue is removed by intense curettage&#44; and bleeding is stopped using electrocautery&#46; The resulting wound heals by secondary intention &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Complete scarring is achieved within approximately 14 days based on daily dressing with antiseptic and antibiotic ointment&#46; The wound progresses without complications after surgery&#44; and the cosmetic outcome is favorable at the 12-month visit &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; Regular follow-up has revealed a reduction in the number of cylindromas and a rate of recurrence of the lesions removed lower than 25&#37;&#46; When the lesion did relapse&#44; the growth was always smaller than the original lesion&#44; thus facilitating surgery&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Our technique enables us to reduce the volume of the lesions by eliminating several growths during the same procedure&#46; This is particularly advantageous in patients who must undergo repeated procedures&#46; It also enables us to concentrate on the emergence of new lesions&#44; since cylindromas rarely recur after removal using this technique&#46; This is because elimination of the lesions by combining several techniques in one procedure &#40;eg&#44; debulking with scissors&#44; followed by curettage of the wound bed&#44; and subsequent use of an electric scalpel&#41; enables almost total necrosis of any remaining cells and destruction of the hair follicles&#44; which are a potential source of new tumors&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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                      "titulo" => "Heterozygous cylindromatosis gene mutation c&#46;1628&#95;1629delct in a family with Brook-Spiegler syndrome"
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                          "etal" => false
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                            3 => "D&#46; Jim&#233;nez"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27688462"
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
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                            2 => "R&#46; Botella"
                            3 => "C&#46; Laredo"
                            4 => "A&#46; Lucas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr"
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                        "paginaFinal" => "672"
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                          0 => array:2 [
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Head Neck Pathol"
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                        0 => array:2 [
                          "etal" => false
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                      ]
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                            3 => "I&#46; Molina"
                            4 => "R&#46; Su&#225;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
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                        "paginaFinal" => "348"
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                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "5"
              "referencia" => array:1 [
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                          "autores" => array:6 [
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                            3 => "A&#46; Fehr"
                            4 => "K&#46; Hodgson"
                            5 => "C&#46; Lord"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/path.4717"
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                        "paginaFinal" => "205"
                        "link" => array:1 [
                          0 => array:2 [
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                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "CO<span class="elsevierStyleInf">2</span> laser treatment of skin cylindromas in Brooke-Spiegler syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Richard"
                            1 => "J&#46;M&#46; Chevalier"
                            2 => "L&#46; Verneuil"
                            3 => "B&#46; Sergent"
                            4 => "A&#46; Tesni&#232;re"
                            5 => "C&#46; Dolfus"
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                        ]
                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.annder.2014.03.006"
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                        "fecha" => "2014"
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                        "paginaFinal" => "353"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24835647"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Familial cylindromatosis and Brooke-Spiegler syndrome&#58; A review of current therapeutic approaches and the surgical challenges posed by two affected families"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
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                            1 => "A&#46;H&#46; Trainer"
                            2 => "J&#46; Burn"
                            3 => "J&#46;A&#46; Langtry"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1524-4725.2009.01142.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2009"
                        "volumen" => "35"
                        "paginaInicial" => "845"
                        "paginaFinal" => "852"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19397670"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Enucleation of cylindromas in Brooke-Spiegler syndrome&#58; A novel surgical technique"
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                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
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                        "volumen" => "40"
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                        "paginaFinal" => "1439"
                        "link" => array:1 [
                          0 => array:2 [
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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                        ]
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                    ]
                  ]
                  "host" => array:1 [
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                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr"
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                        "paginaInicial" => "109"
                        "paginaFinal" => "111"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17397598"
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                      "titulo" => "An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis"
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                        "link" => array:1 [
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Case and Research Letter
A Simple and Effective Method for Treating Cylindromas in Brooke-Spiegler Syndrome
Método simple y efectivo para el tratamiento de los cilindromas en el síndrome de Brooke-Spiegler
S. Lucas-Truyols
Autor para correspondencia
sofialucas89@gmail.com

Corresponding author.
, C. Lloret-Ruiz, F. Millán-Parrilla, E. Gimeno-Carpio
Servicio de Dermatología, Hospital Arnau de Vilanova, Valencia, Spain
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    "titulo" => "A Simple and Effective Method for Treating Cylindromas in Brooke-Spiegler Syndrome"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The genetic skin disease known as Brooke-Spiegler syndrome &#40;BSS&#41; is a rare autosomal dominant condition with more than 50 cases reported to date&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">1</span></a> BSS predisposes to benign adnexal tumors that generally first appear in adulthood and involve the folliculo-sebaceous-apocrine unit&#46; It is characterized by multiple cylindromas&#44; trichoepitheliomas&#44; and&#44; occasionally&#44; spiradenomas&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a> The tumors appear simultaneously&#44; as in BSS&#44; or in isolation&#44; as in familial cylindromatosis and multiple familial trichoepithelioma&#46; Consequently&#44; they seem to have a common origin in a pluripotent cell in the folliculo-sebaceous-apocrine unit&#44; with several phenotypic variants&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Various mutations have been identified in the tumor suppressor gene <span class="elsevierStyleItalic">CYLD</span> on chromosome 16q12-913&#44; thus indicating an association with BSS&#46; <span class="elsevierStyleItalic">CYLD</span> inhibits the tumor necrosis factor &#945; pathway&#44; diminishing expression of nuclear factor &#954;B &#40;NF-&#954;B&#41;&#44; a transcription factor that in turn regulates various antiapoptotic genes involved in the proliferation of adnexa&#46; A loss of the suppressive function of <span class="elsevierStyleItalic">CYLD</span> leads to greater resistance to apoptosis and&#44; consequently&#44; the appearance of these tumors&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#8211;5</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Clinically&#44; cylindromas present as pink nodules on the scalp and behind the ears &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Trichoepitheliomas appear as papules or small translucent or flesh-colored nodules and are located mainly in the center of the face&#44; especially in the nasal region&#46; Spiradenomas&#44; on the other hand&#44; usually present as solitary bluish or flesh-colored nodules that are often painful&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">2</span></a></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The emotional impact of recurrence of these lesions on the face and scalp makes treatment essential&#46; Our literature search revealed various options&#44; such as electrocautery&#44; dermabrasion&#44; radiofrequency&#44; cryotherapy&#44; CO<span class="elsevierStyleInf">2</span> laser&#44;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">6</span></a> radiotherapy &#40;in special cases&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">7</span></a> and&#44; recently&#44; enucleation&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">8</span></a> The treatment recommended for solitary cylindromas is surgical removal&#44; whereas partial or total skin grafting has been proposed for multiple lesions&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">9</span></a> NF-&#954;B inhibitors&#44; such as acetylsalicylic acid and its derivatives&#44; may prove useful both for prevention and for treatment of cylindromas when applied locally&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> Therefore&#44; treatment should be tailored depending on the patient&#44; size of the lesion&#44; number of lesions&#44; therapeutic options available&#44; and the dermatologist&#39;s experience&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">We report the case of an 80-year-old woman with BSS who presented with multiple cylindromas on the scalp that had recurred since adolescence&#44; together with occasional spiradenomas&#46; Her family history was remarkable in that one of her daughters&#44; aged 49 years&#44; had had numerous facial trichoepitheliomas since puberty&#46; She has been followed regularly in our department for the last 10 years&#44; and several lesions have been removed using elliptical excision and direct closure&#46; Given the high number of lesions and the excisions performed&#44; we sought an alternative that would make for more efficient surgery and benefit the patient by reducing the number of trips to the hospital&#46; Five years ago&#44; we began to perform a technique that combined cytoreduction and subsequent curettage of the growths&#46; Our technique is minimally invasive and efficacious&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">After administration of local anesthetic &#40;mepivacaine 2&#37;&#41;&#44; an incision is made with a scalpel or scissor cut to enable resection of most of the tumor mass and create a portal of entry for the next step&#46; After debulking&#44; the remaining lesional tissue is removed by intense curettage&#44; and bleeding is stopped using electrocautery&#46; The resulting wound heals by secondary intention &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; Complete scarring is achieved within approximately 14 days based on daily dressing with antiseptic and antibiotic ointment&#46; The wound progresses without complications after surgery&#44; and the cosmetic outcome is favorable at the 12-month visit &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; Regular follow-up has revealed a reduction in the number of cylindromas and a rate of recurrence of the lesions removed lower than 25&#37;&#46; When the lesion did relapse&#44; the growth was always smaller than the original lesion&#44; thus facilitating surgery&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Our technique enables us to reduce the volume of the lesions by eliminating several growths during the same procedure&#46; This is particularly advantageous in patients who must undergo repeated procedures&#46; It also enables us to concentrate on the emergence of new lesions&#44; since cylindromas rarely recur after removal using this technique&#46; This is because elimination of the lesions by combining several techniques in one procedure &#40;eg&#44; debulking with scissors&#44; followed by curettage of the wound bed&#44; and subsequent use of an electric scalpel&#41; enables almost total necrosis of any remaining cells and destruction of the hair follicles&#44; which are a potential source of new tumors&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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                        "volumen" => "61"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27688462"
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                    0 => array:1 [
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                        "paginaFinal" => "672"
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                            4 => "R&#46; Su&#225;rez"
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                        "paginaFinal" => "348"
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                            1 => "J&#46;M&#46; Chevalier"
                            2 => "L&#46; Verneuil"
                            3 => "B&#46; Sergent"
                            4 => "A&#46; Tesni&#232;re"
                            5 => "C&#46; Dolfus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.annder.2014.03.006"
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                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "2014"
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                        "paginaInicial" => "346"
                        "paginaFinal" => "353"
                        "link" => array:1 [
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                      "titulo" => "Familial cylindromatosis and Brooke-Spiegler syndrome&#58; A review of current therapeutic approaches and the surgical challenges posed by two affected families"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "N&#46; Rajan"
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                            2 => "J&#46; Burn"
                            3 => "J&#46;A&#46; Langtry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1524-4725.2009.01142.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2009"
                        "volumen" => "35"
                        "paginaInicial" => "845"
                        "paginaFinal" => "852"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19397670"
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                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Enucleation of cylindromas in Brooke-Spiegler syndrome&#58; A novel surgical technique"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
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                            2 => "J&#46; Langtry"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000000142"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2014"
                        "volumen" => "40"
                        "paginaInicial" => "1438"
                        "paginaFinal" => "1439"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25361203"
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                  ]
                ]
              ]
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            8 => array:3 [
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              "etiqueta" => "9"
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                0 => array:2 [
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                      "titulo" => "Tumoraciones m&#250;ltiples en cuero cabelludo de presentaci&#243;n familiar"
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                          "etal" => false
                          "autores" => array:5 [
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                            2 => "E&#46; Castellar"
                            3 => "E&#46; Lorda"
                            4 => "C&#46; Alenda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr"
                        "fecha" => "2007"
                        "volumen" => "98"
                        "paginaInicial" => "109"
                        "paginaFinal" => "111"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17397598"
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                      ]
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                  ]
                ]
              ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis"
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                          "etal" => true
                          "autores" => array:6 [
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                            2 => "S&#46;M&#46; Nijman"
                            3 => "A&#46;M&#46; Dirac"
                            4 => "W&#46;J&#46; Mooi"
                            5 => "R&#46; Bernards"
                          ]
                        ]
                      ]
                    ]
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                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2006.07224.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2006"
                        "volumen" => "155"
                        "paginaInicial" => "182"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
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