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López Jiménez, Á. Vargas Nevado, E. Herrera Ceballos" "autores" => array:3 [ 0 => array:2 [ "nombre" => "P. López" "apellidos" => "Jiménez" ] 1 => array:4 [ "nombre" => "Á. Vargas" "apellidos" => "Nevado" "email" => array:1 [ 0 => "avargasn88@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "E. Herrera" "apellidos" => "Ceballos" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Virgen de la Victoria, Málaga, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Penfigoide ampolloso localizado en la aréola mamaria" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 992 "Ancho" => 2666 "Tamanyo" => 226698 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A woman aged 84 years with a past history of hypertension consulted for the appearance of vesiculobullous lesions on her left areola (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). The lesions, which had appeared about 20 days earlier, were pruritic but were not associated with systemic symptoms. Initial treatment with topical antibiotics did not produce a response. Physical examination revealed tense vesicles and blisters with a serous or blood-stained content, and residues of blisters that had ruptured and erosions covered by serosanguinous scabs.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Skin biopsy showed a subepidermal blister with edema of the papillary dermis and an inflammatory infiltrate with abundant eosinophils. Direct immunofluorescence revealed linear deposits of immunoglobulin G and complement along the basement membrane (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Based on these findings, we made a diagnosis of localized bullous pemphigoid. Treatment was started with topical high-strength corticosteroids; improvement was observed after 2 weeks of treatment and no new lesions appeared over 2 years of follow-up. Mammography and screening for tumor markers were performed to exclude underlying neoplastic disease.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Localized bullous pemphigoid is a rare variant. With regard to its presentation only on the breast, triggers that have been suggested include trauma, UV exposure, and radiotherapy related to breast cancer.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Jiménez PL, Nevado ÁV, Ceballos EH. Penfigoide ampolloso localizado en la aréola mamaria. Actas Dermosifiliogr. 2017;108:260.</p>" ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 992 "Ancho" => 2666 "Tamanyo" => 226698 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010800000003/v1_201703250116/S1578219017300276/v1_201703250116/en/main.assets" "Apartado" => array:4 [ "identificador" => "41141" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Dermatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010800000003/v1_201703250116/S1578219017300276/v1_201703250116/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219017300276?idApp=UINPBA000044" ]
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