se ha leído el artículo
array:24 [ "pii" => "S1578219016300373" "issn" => "15782190" "doi" => "10.1016/j.adengl.2016.03.019" "estado" => "S300" "fechaPublicacion" => "2016-06-01" "aid" => "1293" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2015" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2016;107:430" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1505 "formatos" => array:3 [ "EPUB" => 49 "HTML" => 1287 "PDF" => 169 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731015004895" "issn" => "00017310" "doi" => "10.1016/j.ad.2015.04.024" "estado" => "S300" "fechaPublicacion" => "2016-06-01" "aid" => "1293" "copyright" => "AEDV" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2016;107:430" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 308 "formatos" => array:3 [ "EPUB" => 3 "HTML" => 280 "PDF" => 25 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imágenes en Dermatología</span>" "titulo" => "Púrpura retiforme asociada a déficit de proteína S" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "430" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Retiform Purpura Associated With Protein S Deficiency" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1088 "Ancho" => 1300 "Tamanyo" => 261053 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Agudo-García, F. Terrasa-Sagristà, E. Parera-Amer" "autores" => array:3 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Agudo-García" ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Terrasa-Sagristà" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Parera-Amer" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219016300373" "doi" => "10.1016/j.adengl.2016.03.019" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300373?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015004895?idApp=UINPBA000044" "url" => "/00017310/0000010700000005/v1_201605260143/S0001731015004895/v1_201605260143/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219016300270" "issn" => "15782190" "doi" => "10.1016/j.adengl.2016.03.013" "estado" => "S300" "fechaPublicacion" => "2016-06-01" "aid" => "1313" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2016;107:431-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 848 "formatos" => array:3 [ "EPUB" => 54 "HTML" => 622 "PDF" => 172 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Dyshidrotic Eczema Secondary to Intravenous Immunoglobulin Infusion: A Report of 2 Cases" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "431" "paginaFinal" => "433" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Eccema dishidrótico secundario a la infusión de inmunoglobulinas intravenosas: presentación de 2 casos" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 657 "Ancho" => 986 "Tamanyo" => 91376 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Vesicular lesions on an erythematous base on the palm of the second patient.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A.A. Garrido-Ríos, C. Martínez-Morán, J. Borbujo" "autores" => array:3 [ 0 => array:2 [ "nombre" => "A.A." "apellidos" => "Garrido-Ríos" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Martínez-Morán" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Borbujo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731015005141" "doi" => "10.1016/j.ad.2015.09.018" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015005141?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300270?idApp=UINPBA000044" "url" => "/15782190/0000010700000005/v2_201703310310/S1578219016300270/v2_201703310310/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219016300269" "issn" => "15782190" "doi" => "10.1016/j.adengl.2016.03.012" "estado" => "S300" "fechaPublicacion" => "2016-06-01" "aid" => "1291" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2016;107:429" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 907 "formatos" => array:3 [ "EPUB" => 59 "HTML" => 705 "PDF" => 143 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>" "titulo" => "Cutaneous Horn on the Upper Lip" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "429" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Cuerno cutáneo en labio superior" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 453 "Ancho" => 950 "Tamanyo" => 137916 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G. Blasco-Morente, S. Arias-Santiago, I. Pérez-López, J. Aneiros-Fernández" "autores" => array:4 [ 0 => array:2 [ "nombre" => "G." "apellidos" => "Blasco-Morente" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Arias-Santiago" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Pérez-López" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Aneiros-Fernández" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731015004871" "doi" => "10.1016/j.ad.2015.05.018" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731015004871?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300269?idApp=UINPBA000044" "url" => "/15782190/0000010700000005/v2_201703310310/S1578219016300269/v2_201703310310/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>" "titulo" => "Retiform Purpura Associated With Protein S Deficiency" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "430" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. Agudo-García, F. Terrasa-Sagristà, E. Parera-Amer" "autores" => array:3 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Agudo-García" "email" => array:1 [ 0 => "azahara.agudo@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "F." "apellidos" => "Terrasa-Sagristà" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "E." "apellidos" => "Parera-Amer" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Son Llàtzer, Palma de Mallorca, Islas Baleares, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Son Llàtzer, Palma de Mallorca, Islas Baleares, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Púrpura retiforme asociada a déficit de proteína S" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 816 "Ancho" => 975 "Tamanyo" => 188402 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 67-year-old woman with a past history of hypertension and ischemic stroke presented reticulated purpuric lesions with a base covered by necrotic slough (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). The lesions had appeared on both legs over a period of 3 weeks. There was no history of catheterization. The lesions were clinically compatible with retiform purpura, and a number of tests were performed based on the fact that this condition can be secondary to vascular occlusion or a lesion of the blood vessel walls: blood tests including autoimmunity, thrombophilia studies, and phosphorus and calcium metabolism; skin biopsy; transthoracic echocardiography; and blood cultures. Biopsy revealed vascular thrombosis and occlusion with secondary dermoepidermal ischemia, with no signs of vasculitis. The only abnormal finding in the other tests was a low free and functional protein S, suggesting a type <span class="elsevierStyleSmallCaps">I</span> or type <span class="elsevierStyleSmallCaps">III</span> hereditary deficit. During her admission, the lesions ulcerated and erythema developed, associated with increased local temperature and an exudate (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). Antibiotic therapy and heparin anticoagulation were therefore started, with a good response and a progressive improvement. Protein S acts as an antithrombotic factor, inhibiting factors Va and VIIIa; its deficit therefore produces a state of hypercoagulability. Given the high probability of hereditary thrombophilia, we discharged our patient on anticoagulant treatment with acenocoumarol to prevent further thrombotic episodes and undertook study of her family, which excluded further cases among her relatives. We draw attention to the importance of identifying retiform purpura in order to diagnose the underlying cause and start treatment to prevent potentially serious consequences.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Agudo-García A, Terrasa-Sagristà F, Parera-Amer E. Púrpura retiforme asociada a déficit de proteína S. Actas Dermosifiliogr. 2016;107:430.</p>" ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 816 "Ancho" => 975 "Tamanyo" => 188402 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010700000005/v2_201703310310/S1578219016300373/v2_201703310310/en/main.assets" "Apartado" => array:4 [ "identificador" => "41141" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Dermatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010700000005/v2_201703310310/S1578219016300373/v2_201703310310/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219016300373?idApp=UINPBA000044" ]
año/Mes | Html | Total | |
---|---|---|---|
2024 Noviembre | 3 | 4 | 7 |
2024 Octubre | 72 | 44 | 116 |
2024 Septiembre | 84 | 26 | 110 |
2024 Agosto | 100 | 54 | 154 |
2024 Julio | 84 | 34 | 118 |
2024 Junio | 99 | 55 | 154 |
2024 Mayo | 86 | 38 | 124 |
2024 Abril | 85 | 26 | 111 |
2024 Marzo | 72 | 33 | 105 |
2024 Febrero | 63 | 33 | 96 |
2024 Enero | 48 | 30 | 78 |
2023 Diciembre | 72 | 13 | 85 |
2023 Noviembre | 102 | 34 | 136 |
2023 Octubre | 71 | 18 | 89 |
2023 Septiembre | 95 | 28 | 123 |
2023 Agosto | 43 | 16 | 59 |
2023 Julio | 56 | 36 | 92 |
2023 Junio | 54 | 18 | 72 |
2023 Mayo | 72 | 26 | 98 |
2023 Abril | 67 | 28 | 95 |
2023 Marzo | 66 | 24 | 90 |
2023 Febrero | 67 | 24 | 91 |
2023 Enero | 52 | 35 | 87 |
2022 Diciembre | 65 | 43 | 108 |
2022 Noviembre | 31 | 25 | 56 |
2022 Octubre | 42 | 18 | 60 |
2022 Septiembre | 29 | 38 | 67 |
2022 Agosto | 29 | 26 | 55 |
2022 Julio | 26 | 32 | 58 |
2022 Junio | 31 | 20 | 51 |
2022 Mayo | 57 | 44 | 101 |
2022 Abril | 62 | 34 | 96 |
2022 Marzo | 60 | 43 | 103 |
2022 Febrero | 45 | 32 | 77 |
2022 Enero | 66 | 36 | 102 |
2021 Diciembre | 49 | 36 | 85 |
2021 Noviembre | 53 | 40 | 93 |
2021 Octubre | 65 | 48 | 113 |
2021 Septiembre | 47 | 38 | 85 |
2021 Agosto | 58 | 33 | 91 |
2021 Julio | 43 | 31 | 74 |
2021 Junio | 55 | 27 | 82 |
2021 Mayo | 42 | 41 | 83 |
2021 Abril | 84 | 51 | 135 |
2021 Marzo | 131 | 24 | 155 |
2021 Febrero | 94 | 34 | 128 |
2021 Enero | 70 | 12 | 82 |
2020 Diciembre | 71 | 20 | 91 |
2020 Noviembre | 55 | 29 | 84 |
2020 Octubre | 59 | 13 | 72 |
2020 Septiembre | 123 | 15 | 138 |
2020 Agosto | 31 | 18 | 49 |
2020 Julio | 59 | 22 | 81 |
2020 Junio | 54 | 29 | 83 |
2020 Mayo | 41 | 15 | 56 |
2020 Abril | 55 | 22 | 77 |
2020 Marzo | 47 | 18 | 65 |
2020 Febrero | 9 | 0 | 9 |
2020 Enero | 8 | 0 | 8 |
2019 Diciembre | 12 | 0 | 12 |
2019 Noviembre | 6 | 0 | 6 |
2019 Septiembre | 7 | 0 | 7 |
2019 Agosto | 8 | 0 | 8 |
2019 Julio | 12 | 0 | 12 |
2019 Junio | 8 | 0 | 8 |
2019 Mayo | 9 | 0 | 9 |
2019 Abril | 4 | 1 | 5 |
2019 Marzo | 2 | 3 | 5 |
2019 Febrero | 4 | 0 | 4 |
2018 Diciembre | 6 | 0 | 6 |
2018 Noviembre | 8 | 0 | 8 |
2018 Octubre | 15 | 0 | 15 |
2018 Septiembre | 11 | 0 | 11 |
2018 Febrero | 64 | 3 | 67 |
2018 Enero | 73 | 4 | 77 |
2017 Diciembre | 93 | 7 | 100 |
2017 Noviembre | 50 | 4 | 54 |
2017 Octubre | 44 | 5 | 49 |
2017 Septiembre | 83 | 6 | 89 |
2017 Agosto | 216 | 5 | 221 |
2017 Julio | 48 | 1 | 49 |
2017 Junio | 57 | 19 | 76 |
2017 Mayo | 64 | 9 | 73 |
2017 Abril | 54 | 7 | 61 |
2017 Marzo | 36 | 10 | 46 |
2017 Febrero | 28 | 9 | 37 |
2017 Enero | 48 | 9 | 57 |
2016 Diciembre | 65 | 16 | 81 |
2016 Noviembre | 69 | 19 | 88 |
2016 Octubre | 71 | 27 | 98 |
2016 Junio | 0 | 3 | 3 |
2016 Mayo | 0 | 1 | 1 |
2016 Abril | 0 | 1 | 1 |