Case for Diagnosis
Nodular Plaque in the Nasolabial Fold
Placa abollonada en surco nasogeniano
Leído
6784
Vecesse ha leído el artículo
2548
Total PDF
4236
Total HTML
Compartir estadísticas
array:24 [ "pii" => "S1578219014003011" "issn" => "15782190" "doi" => "10.1016/j.adengl.2014.11.003" "estado" => "S300" "fechaPublicacion" => "2015-01-01" "aid" => "995" "copyright" => "Elsevier España, S.L.U. and AEDV" "copyrightAnyo" => "2014" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:63-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1492 "formatos" => array:3 [ "EPUB" => 38 "HTML" => 890 "PDF" => 564 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731014001860" "issn" => "00017310" "doi" => "10.1016/j.ad.2014.02.012" "estado" => "S300" "fechaPublicacion" => "2015-01-01" "aid" => "995" "copyright" => "Elsevier España, S.L.U. y AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:63-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1827 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 927 "PDF" => 898 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Casos para el diagnóstico</span>" "titulo" => "Placa abollonada en surco nasogeniano" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "63" "paginaFinal" => "64" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Nodular Plaque in the Nasolabial Fold" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 599 "Ancho" => 900 "Tamanyo" => 129375 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "E. Piqué-Duran, O. García-Vázquez, K.K. Tang" "autores" => array:3 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "Piqué-Duran" ] 1 => array:2 [ "nombre" => "O." "apellidos" => "García-Vázquez" ] 2 => array:2 [ "nombre" => "K.K." "apellidos" => "Tang" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219014003011" "doi" => "10.1016/j.adengl.2014.11.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014003011?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014001860?idApp=UINPBA000044" "url" => "/00017310/0000010600000001/v2_201706012025/S0001731014001860/v2_201706012025/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219014003023" "issn" => "15782190" "doi" => "10.1016/j.adengl.2014.11.004" "estado" => "S300" "fechaPublicacion" => "2015-01-01" "aid" => "1039" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2015;106:65-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1979 "formatos" => array:3 [ "EPUB" => 44 "HTML" => 1352 "PDF" => 583 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Videos of Surgical Procedures in Dermatology</span>" "titulo" => "Subcutaneous Vector-Running Sutures" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "65" "paginaFinal" => "67" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sutura oblicua subcutánea" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 713 "Ancho" => 950 "Tamanyo" => 115093 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Scar from the excision of a melanoma on the anterior aspect of the right thigh 2 years after performing the vector-running subcutaneous suture. The same case is presented in the video.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Serrano-Ortega, C. Serrano-Falcón, M.A. Fernández-Pugnaire" "autores" => array:3 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Serrano-Ortega" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Serrano-Falcón" ] 2 => array:2 [ "nombre" => "M.A." "apellidos" => "Fernández-Pugnaire" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731014003846" "doi" => "10.1016/j.ad.2014.06.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014003846?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014003023?idApp=UINPBA000044" "url" => "/15782190/0000010600000001/v2_201502060417/S1578219014003023/v2_201502060417/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219014003096" "issn" => "15782190" "doi" => "10.1016/j.adengl.2014.11.011" "estado" => "S300" "fechaPublicacion" => "2015-01-01" "aid" => "993" "copyright" => "Elsevier España, S.L.U. and AEDV" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2015;106:61-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1201 "formatos" => array:3 [ "EPUB" => 49 "HTML" => 890 "PDF" => 262 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Lesions in the Axilla After Hair Removal Using Intense Pulsed Light" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "61" "paginaFinal" => "62" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lesiones axilares después de tratamiento de depilación con luz pulsada intensa" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1000 "Ancho" => 1337 "Tamanyo" => 609962 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification ×<span class="elsevierStyleHsp" style=""></span>20.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Alés-Fernández, L. Ortega-Martínez de Victoria, M.J. García-Fernández de Villalta" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Alés-Fernández" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Ortega-Martínez de Victoria" ] 2 => array:2 [ "nombre" => "M.J." "apellidos" => "García-Fernández de Villalta" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731014001847" "doi" => "10.1016/j.ad.2014.03.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731014001847?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014003096?idApp=UINPBA000044" "url" => "/15782190/0000010600000001/v2_201502060417/S1578219014003096/v2_201502060417/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Nodular Plaque in the Nasolabial Fold" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "63" "paginaFinal" => "64" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "E. Piqué-Duran, O. García-Vázquez, K.K. Tang" "autores" => array:3 [ 0 => array:4 [ "nombre" => "E." "apellidos" => "Piqué-Duran" "email" => array:1 [ 0 => "epiqued@medynet.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "O." "apellidos" => "García-Vázquez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "K.K." "apellidos" => "Tang" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Sección de Dermatología, Hospital Doctor José Molina Orosa de Lanzarote, Arrecife, Las Palmas, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Patología, Hospital Doctor José Molina Orosa de Lanzarote, Arrecife, Las Palmas, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Placa abollonada en surco nasogeniano" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 675 "Ancho" => 900 "Tamanyo" => 283847 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification ×<span class="elsevierStyleHsp" style=""></span>100.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">The patient was an 82-year-old man with a history of ischemic heart disease, aortic valve replacement for severe stenosis, gastrointestinal hemorrhage, benign prostatic hypertrophy, and insertion of a pacemaker.</p><p id="par0010" class="elsevierStylePara elsevierViewall">He had undergone excision of several basal cell carcinomas from the nose and dorsum of the left hand, in addition to one situated in the right nasolabial fold that had been excised some years earlier. He also had a history of actinic cheilitis and Bowen disease on the right forearm.</p><p id="par0015" class="elsevierStylePara elsevierViewall">On this occasion he was seen in outpatients for a pruritic plaque that had arisen in right nasolabial fold 4 months earlier and showed rapid growth.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Physical Examination</span><p id="par0020" class="elsevierStylePara elsevierViewall">On examination there was a well-defined erythematous plaque measuring 2.9<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>1.5<span class="elsevierStyleHsp" style=""></span>cm. The plaque was formed of confluent yellowish papules and nodules that gave it a lumpy appearance. The border of the plaque was in contact with the scar of a previous operation (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Histopathology</span><p id="par0025" class="elsevierStylePara elsevierViewall">On histopathology, the epidermis showed mild acanthosis with orthokeratotic hyperkeratosis and marked solar elastosis. Large, fine-walled cystic structures that contained multilayered basophilic keratin were observed in the papillary and superficial reticular dermis. The few sebaceous glands remaining were hypoplastic. The scar of the previous operation was visible beneath the cysts. Some areas of irregular epithelial cords were present between the cyst and the scar, but there was no atypia and the cords were considered to be reactive (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">What is Your Diagnosis?</span></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Diagnosis</span><p id="par0035" class="elsevierStylePara elsevierViewall">Actinic comedonal plaque.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Clinical Course</span><p id="par0040" class="elsevierStylePara elsevierViewall">The patient died of unrelated causes soon after consultation.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Comment</span><p id="par0045" class="elsevierStylePara elsevierViewall">In 1980, Eastern and Martin<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> described 5 patients under the heading <span class="elsevierStyleItalic">actinic comedonal plaques</span>. A further 3 isolated cases have been reported since that time.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2–4</span></a> In 2003, Morgan et al.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a>used the term <span class="elsevierStyleItalic">multiple follicular cysts, infundibular type with vellus hair and solar elastosis of the ears</span> to describe 3 cases of unilateral plaques on the auricle of the ear that, in our opinion, satisfied the criteria for actinic comedonal plaques.</p><p id="par0050" class="elsevierStylePara elsevierViewall">The majority of cases occur in men of advanced age, with marked solar damage and a history of nonmelanoma skin cancer or actinic keratosis. All cases presented single plaques with nodules or cysts and dilated follicular orifices, with a bluish, yellowish, or erythematous color, probably depending on the predominant type of lesion. The upper limbs are the most common site, though lesions have also been reported on the face and on the ear. Histopathology shows marked solar elastosis, with a thin or acanthotic epidermis, and occasionally there is moderate dyskeratosis. Comedones and follicular dilatation are observed in all cases, with a reduced number of sebaceous glands, while the eccrine glands are unaffected. In 1 case, the lesions appeared to be epithelial invaginations, as also observed in our case.</p><p id="par0055" class="elsevierStylePara elsevierViewall">The actinic comedonal plaque is considered to be a localized variant of Favre-Racouchot syndrome because of its clinical and histopathological similarity. However, the lesions in Favre-Racouchot syndrome are bilateral and localized in the periorbital areas and the temples.</p><p id="par0060" class="elsevierStylePara elsevierViewall">The lesion must be distinguished clinically and histopathologically from comedonal nevus. However, comedonal nevus is usually present at birth or appears during childhood, and often presents a linear distribution. From a histopathological point of view, the lesions must also be differentiated from the residual phase of coral reef granuloma and from chronic <span class="elsevierStyleItalic">Staphylococcus aureus</span> infection,<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> though there is typically a history of infection in the area. Although dyskeratosis is occasionally observed in actinic comedonal plaque, differentiation from actinic keratosis is rarely a problem. An important factor in our case was the clinical similarity of the lesion with basal cell carcinoma, which was the provisional clinical diagnosis.</p><p id="par0065" class="elsevierStylePara elsevierViewall">Treatment by surgery or with topical corticosteroids<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> or vitamin A derivatives<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> has been unsuccessful. Tetracyclines only improved the inflammatory appearance of the lesions.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Resolution has been reported in some cases after cryotherapy.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:7 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Medical History" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Physical Examination" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Histopathology" ] 3 => array:2 [ "identificador" => "sec0020" "titulo" => "Diagnosis" ] 4 => array:2 [ "identificador" => "sec0025" "titulo" => "Clinical Course" ] 5 => array:2 [ "identificador" => "sec0030" "titulo" => "Comment" ] 6 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Piqué-Duran E, García-Vázquez O, Tang K. Placa abollonada en surco nasogeniano. Actas Dermosifiliogr. 2015;106:63–64.</p>" ] ] "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 599 "Ancho" => 900 "Tamanyo" => 143276 ] ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 675 "Ancho" => 900 "Tamanyo" => 283847 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification ×<span class="elsevierStyleHsp" style=""></span>100.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic comedonal plaque" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.S. Eastern" 1 => "S. Martin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1980" "volumen" => "3" "paginaInicial" => "633" "paginaFinal" => "636" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7204681" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic comedonal plaque of the eyelid" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Wojno" 1 => "R.R. Tenzel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Ophthalmology" "fecha" => "1983" "volumen" => "96" "paginaInicial" => "687" "paginaFinal" => "688" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic comedonal plaque--a rare ectopic form of the Favre-Racouchot syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.M. John" 1 => "H. Hamm" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol" "fecha" => "1993" "volumen" => "18" "paginaInicial" => "256" "paginaFinal" => "258" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8348720" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The actinic comedonal plaque" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G. Hauptman" 1 => "A. Kopf" 2 => "H.S. Rabinovitz" 3 => "M. Olivero" 4 => "D. Rivlin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cutis" "fecha" => "1997" "volumen" => "60" "paginaInicial" => "145" "paginaFinal" => "146" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9314619" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multiple follicular cysts, infundibular type with vellus hairs and solar elastosis of the ears: A new dermatoheliosis?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.B. Morgan" 1 => "G.L. Stevens" 2 => "S. Somach" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Cutan Pathol" "fecha" => "2003" "volumen" => "30" "paginaInicial" => "29" "paginaFinal" => "31" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12534801" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic comedonal plaque" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Weedon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1981" "volumen" => "5" "paginaInicial" => "611" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7298928" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010600000001/v2_201502060417/S1578219014003011/v2_201502060417/en/main.assets" "Apartado" => array:4 [ "identificador" => "6154" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case for Diagnosis" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010600000001/v2_201502060417/S1578219014003011/v2_201502060417/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219014003011?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 10 | 6 | 16 |
| 2024 Octubre | 77 | 44 | 121 |
| 2024 Septiembre | 97 | 40 | 137 |
| 2024 Agosto | 136 | 63 | 199 |
| 2024 Julio | 108 | 39 | 147 |
| 2024 Junio | 106 | 35 | 141 |
| 2024 Mayo | 70 | 42 | 112 |
| 2024 Abril | 78 | 29 | 107 |
| 2024 Marzo | 74 | 43 | 117 |
| 2024 Febrero | 71 | 39 | 110 |
| 2024 Enero | 76 | 45 | 121 |
| 2023 Diciembre | 83 | 33 | 116 |
| 2023 Noviembre | 64 | 30 | 94 |
| 2023 Octubre | 73 | 44 | 117 |
| 2023 Septiembre | 73 | 37 | 110 |
| 2023 Agosto | 58 | 29 | 87 |
| 2023 Julio | 63 | 53 | 116 |
| 2023 Junio | 58 | 38 | 96 |
| 2023 Mayo | 52 | 47 | 99 |
| 2023 Abril | 72 | 39 | 111 |
| 2023 Marzo | 47 | 42 | 89 |
| 2023 Febrero | 48 | 27 | 75 |
| 2023 Enero | 58 | 40 | 98 |
| 2022 Diciembre | 53 | 50 | 103 |
| 2022 Noviembre | 25 | 22 | 47 |
| 2022 Octubre | 32 | 23 | 55 |
| 2022 Septiembre | 53 | 45 | 98 |
| 2022 Agosto | 38 | 39 | 77 |
| 2022 Julio | 39 | 37 | 76 |
| 2022 Junio | 49 | 29 | 78 |
| 2022 Mayo | 75 | 39 | 114 |
| 2022 Abril | 65 | 51 | 116 |
| 2022 Marzo | 69 | 58 | 127 |
| 2022 Febrero | 60 | 22 | 82 |
| 2022 Enero | 70 | 46 | 116 |
| 2021 Diciembre | 53 | 41 | 94 |
| 2021 Noviembre | 48 | 44 | 92 |
| 2021 Octubre | 102 | 48 | 150 |
| 2021 Septiembre | 64 | 38 | 102 |
| 2021 Agosto | 68 | 27 | 95 |
| 2021 Julio | 53 | 31 | 84 |
| 2021 Junio | 39 | 29 | 68 |
| 2021 Mayo | 48 | 23 | 71 |
| 2021 Abril | 85 | 57 | 142 |
| 2021 Marzo | 52 | 38 | 90 |
| 2021 Febrero | 46 | 26 | 72 |
| 2021 Enero | 43 | 24 | 67 |
| 2020 Diciembre | 52 | 15 | 67 |
| 2020 Noviembre | 32 | 18 | 50 |
| 2020 Octubre | 46 | 27 | 73 |
| 2020 Septiembre | 36 | 8 | 44 |
| 2020 Agosto | 25 | 27 | 52 |
| 2020 Julio | 28 | 9 | 37 |
| 2020 Junio | 33 | 25 | 58 |
| 2020 Mayo | 40 | 36 | 76 |
| 2020 Abril | 37 | 28 | 65 |
| 2020 Marzo | 33 | 16 | 49 |
| 2020 Febrero | 4 | 8 | 12 |
| 2020 Enero | 4 | 3 | 7 |
| 2019 Diciembre | 4 | 7 | 11 |
| 2019 Noviembre | 4 | 5 | 9 |
| 2019 Octubre | 0 | 6 | 6 |
| 2019 Septiembre | 4 | 8 | 12 |
| 2019 Agosto | 4 | 5 | 9 |
| 2019 Julio | 4 | 12 | 16 |
| 2019 Junio | 4 | 27 | 31 |
| 2019 Mayo | 3 | 54 | 57 |
| 2019 Abril | 4 | 44 | 48 |
| 2019 Marzo | 0 | 10 | 10 |
| 2019 Febrero | 2 | 4 | 6 |
| 2019 Enero | 0 | 7 | 7 |
| 2018 Diciembre | 1 | 11 | 12 |
| 2018 Noviembre | 4 | 6 | 10 |
| 2018 Octubre | 1 | 0 | 1 |
| 2018 Septiembre | 4 | 8 | 12 |
| 2018 Agosto | 0 | 1 | 1 |
| 2018 Julio | 0 | 5 | 5 |
| 2018 Junio | 0 | 1 | 1 |
| 2018 Mayo | 0 | 2 | 2 |
| 2018 Abril | 0 | 5 | 5 |
| 2018 Marzo | 1 | 0 | 1 |
| 2018 Febrero | 21 | 9 | 30 |
| 2018 Enero | 35 | 6 | 41 |
| 2017 Diciembre | 36 | 7 | 43 |
| 2017 Noviembre | 34 | 8 | 42 |
| 2017 Octubre | 23 | 8 | 31 |
| 2017 Septiembre | 35 | 4 | 39 |
| 2017 Agosto | 66 | 15 | 81 |
| 2017 Julio | 30 | 8 | 38 |
| 2017 Junio | 47 | 34 | 81 |
| 2017 Mayo | 38 | 13 | 51 |
| 2017 Abril | 24 | 9 | 33 |
| 2017 Marzo | 20 | 17 | 37 |
| 2017 Febrero | 19 | 11 | 30 |
| 2017 Enero | 17 | 6 | 23 |
| 2016 Diciembre | 25 | 16 | 41 |
| 2016 Noviembre | 40 | 12 | 52 |
| 2016 Octubre | 26 | 12 | 38 |
| 2016 Septiembre | 0 | 12 | 12 |
| 2016 Agosto | 0 | 2 | 2 |
| 2016 Julio | 10 | 1 | 11 |
| 2016 Junio | 22 | 1 | 23 |
| 2016 Mayo | 17 | 26 | 43 |
| 2016 Abril | 22 | 17 | 39 |
| 2016 Marzo | 12 | 11 | 23 |
| 2016 Febrero | 14 | 13 | 27 |
| 2016 Enero | 9 | 9 | 18 |
| 2015 Diciembre | 11 | 6 | 17 |
| 2015 Noviembre | 15 | 2 | 17 |
| 2015 Octubre | 9 | 0 | 9 |
| 2015 Septiembre | 12 | 1 | 13 |
| 2015 Agosto | 3 | 3 | 6 |
| 2015 Julio | 22 | 4 | 26 |
| 2015 Junio | 25 | 4 | 29 |
| 2015 Mayo | 30 | 6 | 36 |
| 2015 Abril | 31 | 4 | 35 |
| 2015 Marzo | 36 | 11 | 47 |
| 2015 Febrero | 5 | 1 | 6 |
Mostrar todo
