Case and research letter
The Rainbow Pattern and Rosettes in Cutaneous Scars
Patrón dermoscópico en arcoíris y rosetas en cicatrices cutáneas
L. Pérez-Pérez
, J. García-Gavín, F. Allegue, A. Zulaica
Autor para correspondencia
Servicio de Dermatología, Complejo Hospitalario Universitario de Vigo, Vigo, Spain
Leído
8354
Vecesse ha leído el artículo
2571
Total PDF
5783
Total HTML
Compartir estadísticas
array:24 [ "pii" => "S1578219013002783" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.12.014" "estado" => "S300" "fechaPublicacion" => "2014-01-01" "aid" => "812" "copyright" => "Elsevier España, S.L. and AEDV" "copyrightAnyo" => "2012" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2014;105:96-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2844 "formatos" => array:3 [ "EPUB" => 46 "HTML" => 2328 "PDF" => 470 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731013000835" "issn" => "00017310" "doi" => "10.1016/j.ad.2012.12.017" "estado" => "S300" "fechaPublicacion" => "2014-01-01" "aid" => "812" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2014;105:96-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4062 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 3033 "PDF" => 1025 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Patrón dermoscópico en arcoíris y rosetas en cicatrices cutáneas" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "96" "paginaFinal" => "97" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "The Rainbow Pattern and Rosettes in Cutaneous Scars" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 620 "Ancho" => 900 "Tamanyo" => 89461 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Exploración de las lesiones mediante un dermatoscopio de luz polarizada acoplado a una cámara fotográfica modelo Canon Powershot A160- DermLite Foto, 3 Gen LLC, California [Estados Unidos]). Se observan rosetas (señaladas con un círculo blanco en la lesión izquierda; se aprecian en mayor número en la zona central de la lesión derecha), vasos irregulares y un patrón en arcoíris prominente.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L. Pérez-Pérez, J. García-Gavín, F. Allegue, A. Zulaica" "autores" => array:4 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Pérez-Pérez" ] 1 => array:2 [ "nombre" => "J." "apellidos" => "García-Gavín" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Allegue" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Zulaica" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219013002783" "doi" => "10.1016/j.adengl.2012.12.014" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002783?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731013000835?idApp=UINPBA000044" "url" => "/00017310/0000010500000001/v1_201401250106/S0001731013000835/v1_201401250106/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219013002795" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.11.027" "estado" => "S300" "fechaPublicacion" => "2014-01-01" "aid" => "773" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2014;105:97-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3116 "formatos" => array:3 [ "EPUB" => 43 "HTML" => 2430 "PDF" => 643 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and research letter</span>" "titulo" => "Dermoscopic Rainbow Pattern in Atypical Fibroxanthoma" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "97" "paginaFinal" => "99" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Patrón dermatoscópico en arcoíris en fibroxantoma atípico" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 922 "Ancho" => 900 "Tamanyo" => 109009 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Tumor on the scalp and nearby actinic keratoses.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "G. Pitarch" "autores" => array:1 [ 0 => array:2 [ "nombre" => "G." "apellidos" => "Pitarch" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012005480" "doi" => "10.1016/j.ad.2012.11.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012005480?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002795?idApp=UINPBA000044" "url" => "/15782190/0000010500000001/v1_201401220123/S1578219013002795/v1_201401220123/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219013002771" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.10.020" "estado" => "S300" "fechaPublicacion" => "2014-01-01" "aid" => "758" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2014;105:94-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1539 "formatos" => array:3 [ "EPUB" => 47 "HTML" => 1170 "PDF" => 322 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>" "titulo" => "Neuroendocrine TumorWith an Atypical Clinical Course: A Description of 2 Cases" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "94" "paginaFinal" => "96" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tumor neuroendocrino: descripción de 2 casos de evolución atípica" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 598 "Ancho" => 900 "Tamanyo" => 96404 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Two erythematous plaques in the right paranasal-infrapalpebral region (image taken after excision of 1 of the lesions).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I. Arrue, M.A. Arregui, B. Catón, R. Soloeta" "autores" => array:4 [ 0 => array:2 [ "nombre" => "I." "apellidos" => "Arrue" ] 1 => array:2 [ "nombre" => "M.A." "apellidos" => "Arregui" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Catón" ] 3 => array:2 [ "nombre" => "R." "apellidos" => "Soloeta" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012004887" "doi" => "10.1016/j.ad.2012.10.014" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012004887?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002771?idApp=UINPBA000044" "url" => "/15782190/0000010500000001/v1_201401220123/S1578219013002771/v1_201401220123/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and research letter</span>" "titulo" => "The Rainbow Pattern and Rosettes in Cutaneous Scars" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "96" "paginaFinal" => "97" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "L. Pérez-Pérez, J. García-Gavín, F. Allegue, A. Zulaica" "autores" => array:4 [ 0 => array:4 [ "nombre" => "L." "apellidos" => "Pérez-Pérez" "email" => array:1 [ 0 => "lidiacomba@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "J." "apellidos" => "García-Gavín" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Allegue" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Zulaica" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Complejo Hospitalario Universitario de Vigo, Vigo, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondig author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Patrón dermoscópico en arcoíris y rosetas en cicatrices cutáneas" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 620 "Ancho" => 900 "Tamanyo" => 88128 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Image of the lesions obtained with a polarized light dermatoscope attached to a Canon Powershot A160 camera using the DermLite Foto attachment (3Gen LLC). Rosettes (indicated by a white circle in the lesion on the left; a larger number of rosettes are seen in the central area of the lesion on the right) are in evidence, along with irregularly shaped vessels and a clear rainbow pattern.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Recent studies carried out using polarized light dermoscopy have characterized the rainbow pattern and the rosette sign as being dermoscopic features of Kaposi sarcoma and actinic keratosis, respectively.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> These structures have also been observed in other skin lesions of varying origin, although more infrequently.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3–7</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">We observed both structures in a 13-year-old patient who visited our department because of several pruritic lesions on both knees. The lesions had appeared 2 weeks after the patient had applied an over-the-counter treatment for verruca vulgaris (Cryopharma; Chefaro Española) to the site.</p><p id="par0015" class="elsevierStylePara elsevierViewall">A dermatological examination revealed multiple round, erythematous-violaceous lesions measuring 0.7<span class="elsevierStyleHsp" style=""></span>cm to 1 cm in diameter. The lesions were well-defined, had a smooth surface, and were located on both knees (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Using a polarized light dermoscope (Dermlite II PRO HR; 3Gen), we observed a rainbow pattern comprising several colors of the rainbow spectrum (yellow-orange, blue-violet) radiating homogeneously in a flame pattern out from the center to the periphery of each lesion. We also observed numerous irregular vessels, telangiectasias, and groups of varying numbers of whitish points (rosettes). The results of a histopathological study showed a slightly atrophic epidermis on top of bands of fibroblasts, abundant collagen bundles, and numerous vessels arranged parallel or perpendicular to the epidermis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>); all these findings were consistent with scarring.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">First described by Hu et al.,<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> the rainbow pattern is a multicolored dermoscopic feature in which all or part of a lesion contains areas showing various colors of the rainbow. Together with a bluish-reddish coloration, a scaly surface, and small brown globules, the rainbow pattern is one of the most common dermoscopic structures of Kaposi sarcoma and it is found in up to 36% of such lesions.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,8</span></a> Some authors consider the rainbow pattern to be highly specific for Kaposi sarcoma (sensitivity, 36.2%; specificity, 100%).<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> However, the same pattern has been described in melanoma,<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> basal cell carcinoma,<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> stasis dermatitis, and lichen planus.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The rainbow pattern is probably caused by a complex physical phenomenon in which polarized light interacts with various elements as it passes through tissue. Cheng et al.<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8,9</span></a> hypothesize that the light beam is diffracted as it penetrates the dermis, while Vázquez-López et al.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> cite dichroism, a phenomenon by which light in different states of polarization undergoes variable degrees of absorbance and retardance when it interacts with the components of the tissue and therefore gives off different colors.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">This pattern is not associated with any particular histological structure.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> Cheng et al.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> observed that Kaposi sarcoma lesions exhibiting the rainbow pattern were made up of numerous vascular lumens lined by inconspicuous endothelial cells and scant stromal tissue, while the lesions with no rainbow pattern exhibited more abundant stromal tissue. The rainbow pattern may be linked to the vascular structure of the lesion,<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8,9</span></a> a hypothesis that might explain why the pattern is found in other types of skin lesions with active vascularization, such as our patient's scars.</p><p id="par0035" class="elsevierStylePara elsevierViewall">When first described in actinic keratosis, rosettes were characterized as “4 white points arranged as a 4-leaf clover.”<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The sign has since been reported in other skin lesions such as squamous cell carcinoma, basal cell carcinoma, melanoma, and lichenoid keratosis.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3–7</span></a> Rosettes are believed to be the result of an optical effect caused by interaction between polarized light and follicular openings.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">The rainbow pattern and rosettes are not considered to be specific dermoscopic features of the lesion. Since it appears that they are secondary effects of the interaction between different skin structures and polarized light, they will likely be observed in various types of skin lesions.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Pérez-Pérez L, García-Gavín J, Allegue F, Zulaica A. Patrón dermoscópico en arcoíris y rosetas en cicatrices cutáneas. Actas Dermosifiliogr. 2014;105:96–97.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 656 "Ancho" => 953 "Tamanyo" => 77499 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Rounded, violaceous papular lesions on the knees of the patient. A, Right knee. B, Left knee.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 620 "Ancho" => 900 "Tamanyo" => 88128 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Image of the lesions obtained with a polarized light dermatoscope attached to a Canon Powershot A160 camera using the DermLite Foto attachment (3Gen LLC). Rosettes (indicated by a white circle in the lesion on the left; a larger number of rosettes are seen in the central area of the lesion on the right) are in evidence, along with irregularly shaped vessels and a clear rainbow pattern.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopy of Kaposi's sarcoma: Areas exhibiting the multicoloured ‘rainbow pattern’" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.C. Hu" 1 => "C.L. Ke" 2 => "C.H. Lee" 3 => "C.S. Wu" 4 => "G.S. Chen" 5 => "S.T. Cheng" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-3083.2009.03239.x" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2009" "volumen" => "23" "paginaInicial" => "1128" "paginaFinal" => "1132" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19438977" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New dermoscopic pattern in actinic keratosis and related conditions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "F. Cuellar" 1 => "A. Vilalta" 2 => "S. Puig" 3 => "J. Palou" 4 => "G. Salerni" 5 => "J. Malvehy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2009.86" "Revista" => array:5 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2009" "volumen" => "145" "paginaInicial" => "732" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19528439" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic rainbow pattern in basal cell carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "B. Garcia-Garcia" 1 => "N. Perez-Oliva" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-3083.2009.03548.x" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2010" "volumen" => "24" "paginaInicial" => "499" "paginaFinal" => "500" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20028446" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic rainbow pattern in non-Kaposi sarcoma lesions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "F. Vázquez-López" 1 => "B. García-García" 2 => "M. Rajadhyaksha" 3 => "A.A. Marghoob" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2009.09225.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2009" "volumen" => "161" "paginaInicial" => "474" "paginaFinal" => "475" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19438855" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic features of basal cell carcinomas: Differences in appearance under non-polarized and polarized light" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T.N. Liebman" 1 => "N. Jaimes-Lopez" 2 => "Y. Balagula" 3 => "H.S. Rabinovitz" 4 => "S.Q. Wang" 5 => "S.W. Dusza" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1524-4725.2011.02205.x" "Revista" => array:6 [ "tituloSerie" => "Dermatol Surg" "fecha" => "2012" "volumen" => "38" "paginaInicial" => "392" "paginaFinal" => "399" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22093161" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rosettes may be observed in a range of conditions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "T.N. Liebman" 1 => "A. Scope" 2 => "H. Rabinovitz" 3 => "R.P. Braun" 4 => "A.A. Marghoob" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2011.312" "Revista" => array:5 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2011" "volumen" => "147" "paginaInicial" => "1468" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22184782" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "White shiny structures: Dermoscopic features revealed under polarized light" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T.N. Liebman" 1 => "H.S. Rabinovitz" 2 => "S.W. Dusza" 3 => "A.A. Marghoob" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-3083.2011.04317.x" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2011" "volumen" => "26" "paginaInicial" => "1493" "paginaFinal" => "1497" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22035217" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic rainbow pattern in non-Kaposi sarcoma lesions-reply" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.T. Cheng" 1 => "C.L. Ke" 2 => "C.H. Lee" 3 => "C.S. Wu" 4 => "G.S. Chen" 5 => "S.C. Hu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2009.09554.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2010" "volumen" => "162" "paginaInicial" => "458" "paginaFinal" => "459" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19919627" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rainbow pattern in Kaposi's sarcoma under polarized dermoscopy: A dermoscopic pathological study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.T. Cheng" 1 => "C.L. Ke" 2 => "C.H. Lee" 3 => "C.S. Wu" 4 => "G.S. Chen" 5 => "S.C. Hu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2008.08940.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2009" "volumen" => "160" "paginaInicial" => "801" "paginaFinal" => "809" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19067686" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010500000001/v1_201401220123/S1578219013002783/v1_201401220123/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010500000001/v1_201401220123/S1578219013002783/v1_201401220123/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013002783?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 8 | 7 | 15 |
| 2024 Octubre | 96 | 62 | 158 |
| 2024 Septiembre | 92 | 31 | 123 |
| 2024 Agosto | 125 | 60 | 185 |
| 2024 Julio | 111 | 40 | 151 |
| 2024 Junio | 131 | 41 | 172 |
| 2024 Mayo | 109 | 43 | 152 |
| 2024 Abril | 80 | 29 | 109 |
| 2024 Marzo | 82 | 28 | 110 |
| 2024 Febrero | 70 | 38 | 108 |
| 2024 Enero | 70 | 41 | 111 |
| 2023 Diciembre | 82 | 33 | 115 |
| 2023 Noviembre | 63 | 36 | 99 |
| 2023 Octubre | 77 | 42 | 119 |
| 2023 Septiembre | 80 | 38 | 118 |
| 2023 Agosto | 58 | 32 | 90 |
| 2023 Julio | 92 | 39 | 131 |
| 2023 Junio | 68 | 22 | 90 |
| 2023 Mayo | 83 | 32 | 115 |
| 2023 Abril | 69 | 28 | 97 |
| 2023 Marzo | 74 | 29 | 103 |
| 2023 Febrero | 67 | 18 | 85 |
| 2023 Enero | 50 | 59 | 109 |
| 2022 Diciembre | 47 | 49 | 96 |
| 2022 Noviembre | 32 | 28 | 60 |
| 2022 Octubre | 29 | 45 | 74 |
| 2022 Septiembre | 38 | 56 | 94 |
| 2022 Agosto | 23 | 36 | 59 |
| 2022 Julio | 26 | 45 | 71 |
| 2022 Junio | 36 | 41 | 77 |
| 2022 Mayo | 104 | 50 | 154 |
| 2022 Abril | 101 | 64 | 165 |
| 2022 Marzo | 93 | 57 | 150 |
| 2022 Febrero | 60 | 41 | 101 |
| 2022 Enero | 81 | 58 | 139 |
| 2021 Diciembre | 39 | 45 | 84 |
| 2021 Noviembre | 71 | 47 | 118 |
| 2021 Octubre | 48 | 39 | 87 |
| 2021 Septiembre | 39 | 40 | 79 |
| 2021 Agosto | 70 | 76 | 146 |
| 2021 Julio | 39 | 59 | 98 |
| 2021 Junio | 46 | 29 | 75 |
| 2021 Mayo | 33 | 40 | 73 |
| 2021 Abril | 107 | 56 | 163 |
| 2021 Marzo | 50 | 43 | 93 |
| 2021 Febrero | 50 | 36 | 86 |
| 2021 Enero | 53 | 15 | 68 |
| 2020 Diciembre | 24 | 16 | 40 |
| 2020 Noviembre | 21 | 17 | 38 |
| 2020 Octubre | 29 | 9 | 38 |
| 2020 Septiembre | 21 | 12 | 33 |
| 2020 Agosto | 24 | 19 | 43 |
| 2020 Julio | 38 | 13 | 51 |
| 2020 Junio | 40 | 29 | 69 |
| 2020 Mayo | 29 | 20 | 49 |
| 2020 Abril | 38 | 20 | 58 |
| 2020 Marzo | 34 | 23 | 57 |
| 2020 Febrero | 6 | 0 | 6 |
| 2020 Enero | 5 | 0 | 5 |
| 2019 Diciembre | 8 | 5 | 13 |
| 2019 Noviembre | 4 | 4 | 8 |
| 2019 Octubre | 0 | 1 | 1 |
| 2019 Septiembre | 8 | 7 | 15 |
| 2019 Agosto | 4 | 5 | 9 |
| 2019 Julio | 4 | 9 | 13 |
| 2019 Junio | 6 | 20 | 26 |
| 2019 Mayo | 4 | 48 | 52 |
| 2019 Abril | 2 | 14 | 16 |
| 2019 Marzo | 2 | 8 | 10 |
| 2019 Febrero | 2 | 5 | 7 |
| 2019 Enero | 2 | 0 | 2 |
| 2018 Diciembre | 1 | 3 | 4 |
| 2018 Noviembre | 2 | 0 | 2 |
| 2018 Octubre | 2 | 0 | 2 |
| 2018 Septiembre | 3 | 0 | 3 |
| 2018 Marzo | 2 | 2 | 4 |
| 2018 Febrero | 93 | 13 | 106 |
| 2018 Enero | 71 | 4 | 75 |
| 2017 Diciembre | 98 | 10 | 108 |
| 2017 Noviembre | 57 | 2 | 59 |
| 2017 Octubre | 73 | 6 | 79 |
| 2017 Septiembre | 53 | 10 | 63 |
| 2017 Agosto | 50 | 8 | 58 |
| 2017 Julio | 45 | 9 | 54 |
| 2017 Junio | 57 | 19 | 76 |
| 2017 Mayo | 56 | 8 | 64 |
| 2017 Abril | 49 | 11 | 60 |
| 2017 Marzo | 57 | 23 | 80 |
| 2017 Febrero | 121 | 13 | 134 |
| 2017 Enero | 40 | 7 | 47 |
| 2016 Diciembre | 53 | 17 | 70 |
| 2016 Noviembre | 63 | 15 | 78 |
| 2016 Octubre | 131 | 11 | 142 |
| 2016 Septiembre | 197 | 15 | 212 |
| 2016 Agosto | 185 | 9 | 194 |
| 2016 Julio | 71 | 7 | 78 |
| 2016 Junio | 10 | 11 | 21 |
| 2016 Mayo | 13 | 9 | 22 |
| 2016 Abril | 8 | 1 | 9 |
| 2016 Marzo | 4 | 2 | 6 |
| 2016 Febrero | 12 | 4 | 16 |
| 2016 Enero | 4 | 2 | 6 |
| 2015 Diciembre | 6 | 2 | 8 |
| 2015 Noviembre | 7 | 3 | 10 |
| 2015 Octubre | 3 | 4 | 7 |
| 2015 Septiembre | 1 | 2 | 3 |
| 2015 Agosto | 5 | 1 | 6 |
| 2015 Julio | 74 | 1 | 75 |
| 2015 Junio | 52 | 4 | 56 |
| 2015 Mayo | 65 | 6 | 71 |
| 2015 Abril | 46 | 7 | 53 |
| 2015 Marzo | 41 | 4 | 45 |
| 2015 Febrero | 21 | 5 | 26 |
| 2015 Enero | 25 | 1 | 26 |
| 2014 Diciembre | 27 | 6 | 33 |
| 2014 Noviembre | 27 | 3 | 30 |
| 2014 Octubre | 33 | 2 | 35 |
| 2014 Septiembre | 27 | 3 | 30 |
| 2014 Agosto | 16 | 4 | 20 |
| 2014 Julio | 20 | 9 | 29 |
| 2014 Junio | 30 | 6 | 36 |
| 2014 Mayo | 27 | 7 | 34 |
| 2014 Abril | 23 | 5 | 28 |
| 2014 Marzo | 17 | 5 | 22 |
| 2014 Febrero | 2 | 3 | 5 |
Mostrar todo
