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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p class="elsevierStyleSimplePara elsevierViewall">Corticosteroid contact dermatitis and its patch testing are subject to certain peculiarities that we should be aware of&#46;</p> <span class="elsevierStyleSectionTitle">Materials and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We performed a retrospective study of all patients who underwent patch tests with a corticosteroid battery in the Skin Allergy Unit of the Dermatology Department of Hospital General Universitario&#44; Alicante&#44; Spain&#44; between October 2004 and June 2007&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">During the study period&#44; patch tests were performed on 1065 patients in our allergy unit&#46; A corticosteroid battery was used in 34 patients &#40;3&#46;1&#37;&#41;&#46; Fourteen patients were positive for budesonide or tixocortol in the standard battery&#59; 20 were negative for these allergens but there was a clinical suspicion of steroid allergy&#46; At least one positive reaction in the corticosteroid battery was observed in 15 patients &#40;44&#46;1&#37;&#41;&#46;The substance most commonly implicated was budesonide &#40;13 patients sensitized&#41;&#46; The corticosteroid battery revealed sensitization to other groups of corticosteroids in 4 of the 15 patients with corticosteroid sensitization&#46; Seventeen patients brought drugs that were also tested&#44; obtaining positive results for 10 substances&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Allergens for contact dermatitis due to corticosteroids included in the standard battery &#40;budesonide and tixocortol&#41; detected 93&#37; of patients who are sensitized to steroids&#59; there would appear to be little benefit in performing a corticosteroid battery if those markers are negative&#46; The battery of corticosteroids and the drugs provided by patients were useful to define more exactly the corticosteroid classes that the patient should avoid&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">La dermatitis de contacto por corticoides y la realizaci&#243;n de las pruebas epicut&#225;neas con estas sustancias presentan peculiaridades que hay que conocer&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Realizamos un estudio retrospectivo de todos los pacientes en los que se aplic&#243; la bater&#237;a de corticoides en la Unidad de Alergia Cut&#225;nea de la Secci&#243;n de Dermatolog&#237;a del Hospital General Universitario de Alicante&#44; durante el per&#237;odo comprendido entre octubre de 2004 y junio de 2007&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Durante el per&#237;odo de estudio se atendieron 1&#46;065 pacientes&#44; a 34 de ellos &#40;3&#44;1&#37;&#41; se les aplic&#243; la bater&#237;a de corticoides&#44; 14 pacientes con budesonida o tixocortol positivos en la bater&#237;a est&#225;ndar y 20 con estos marcadores negativos pero con sospecha cl&#237;nica de alergia a corticoides&#46; Quince pacientes &#40;44&#44;1&#37;&#41; obtuvieron alg&#250;n positivo en la bater&#237;a de corticoides&#46; La sustancia que m&#225;s positivos obtuvo fue budesonida &#40;13 pacientes sensibilizados&#41;&#46; En 4 de 15 pacientes el uso de la bater&#237;a de corticoides inform&#243; de sensibilizaci&#243;n a otros grupos de corticoides&#46; A 17 pacientes se les aplicaron los medicamentos aportados por ellos&#44; obteni&#233;ndose 10 sustancias positivas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los marcadores para la dermatitis de contacto por corticoides presentes en la bater&#237;a est&#225;ndar &#40;budesonida y tixocortol&#41; detectaron el 93&#37; de pacientes sensibilizados a corticoides&#44; por lo que no parece rentable aplicar la bater&#237;a de corticoides si dichos marcadores son negativos&#46; La bater&#237;a de corticoides y los propios f&#225;rmacos aportados por los pacientes fueron &#250;tiles para definir mejor los grupos de corticoides que estos no pueden utilizar&#46;</p>"
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                      "titulo" => "Recommendation to include budesonide and tixocortol pivalate in the European standard series&#46; ESCD and EECDRG&#46; European Society of Contact Dermatitis"
                      "autores" => array:1 [
                        0 => array:2 [
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                          "autores" => array:4 [
                            0 => "M&#46; Isaksson"
                            1 => "F&#46;M&#46; Brand&#227;o"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10902588"
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                          "etal" => false
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                      "titulo" => "Results of patch testing to a corticosteroid series&#58; a retrospective review of 1188 patients during 6 years at Mayo Clinic"
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Original articles
Allergic Contact Dermatitis Due to Corticosteroids: A 3-Year Retrospective Study in a Hospital Skin Allergy Unit
Dermatitis de Contacto por Corticoides. Estudio Retrospectivo de 3 años en una Unidad de Alergia Cutánea Hospitalaria
M. Pérez-Crespo
Autor para correspondencia
mariaperezcrespo@hotmail.com

Correspondence: Servicio de Dermatología, Hospital General Universitario de Alicante, C/ Pintor Baeza, s/n. 03010 Alicante, Spain.
, J.F. Silvestre, A. Lucas, J. Mataix, I. Ballester
Sección de Dermatología, Hospital General Universitario de Alicante, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p class="elsevierStyleSimplePara elsevierViewall">Corticosteroid contact dermatitis and its patch testing are subject to certain peculiarities that we should be aware of&#46;</p> <span class="elsevierStyleSectionTitle">Materials and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We performed a retrospective study of all patients who underwent patch tests with a corticosteroid battery in the Skin Allergy Unit of the Dermatology Department of Hospital General Universitario&#44; Alicante&#44; Spain&#44; between October 2004 and June 2007&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">During the study period&#44; patch tests were performed on 1065 patients in our allergy unit&#46; A corticosteroid battery was used in 34 patients &#40;3&#46;1&#37;&#41;&#46; Fourteen patients were positive for budesonide or tixocortol in the standard battery&#59; 20 were negative for these allergens but there was a clinical suspicion of steroid allergy&#46; At least one positive reaction in the corticosteroid battery was observed in 15 patients &#40;44&#46;1&#37;&#41;&#46;The substance most commonly implicated was budesonide &#40;13 patients sensitized&#41;&#46; The corticosteroid battery revealed sensitization to other groups of corticosteroids in 4 of the 15 patients with corticosteroid sensitization&#46; Seventeen patients brought drugs that were also tested&#44; obtaining positive results for 10 substances&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Allergens for contact dermatitis due to corticosteroids included in the standard battery &#40;budesonide and tixocortol&#41; detected 93&#37; of patients who are sensitized to steroids&#59; there would appear to be little benefit in performing a corticosteroid battery if those markers are negative&#46; The battery of corticosteroids and the drugs provided by patients were useful to define more exactly the corticosteroid classes that the patient should avoid&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">La dermatitis de contacto por corticoides y la realizaci&#243;n de las pruebas epicut&#225;neas con estas sustancias presentan peculiaridades que hay que conocer&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Realizamos un estudio retrospectivo de todos los pacientes en los que se aplic&#243; la bater&#237;a de corticoides en la Unidad de Alergia Cut&#225;nea de la Secci&#243;n de Dermatolog&#237;a del Hospital General Universitario de Alicante&#44; durante el per&#237;odo comprendido entre octubre de 2004 y junio de 2007&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Durante el per&#237;odo de estudio se atendieron 1&#46;065 pacientes&#44; a 34 de ellos &#40;3&#44;1&#37;&#41; se les aplic&#243; la bater&#237;a de corticoides&#44; 14 pacientes con budesonida o tixocortol positivos en la bater&#237;a est&#225;ndar y 20 con estos marcadores negativos pero con sospecha cl&#237;nica de alergia a corticoides&#46; Quince pacientes &#40;44&#44;1&#37;&#41; obtuvieron alg&#250;n positivo en la bater&#237;a de corticoides&#46; La sustancia que m&#225;s positivos obtuvo fue budesonida &#40;13 pacientes sensibilizados&#41;&#46; En 4 de 15 pacientes el uso de la bater&#237;a de corticoides inform&#243; de sensibilizaci&#243;n a otros grupos de corticoides&#46; A 17 pacientes se les aplicaron los medicamentos aportados por ellos&#44; obteni&#233;ndose 10 sustancias positivas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los marcadores para la dermatitis de contacto por corticoides presentes en la bater&#237;a est&#225;ndar &#40;budesonida y tixocortol&#41; detectaron el 93&#37; de pacientes sensibilizados a corticoides&#44; por lo que no parece rentable aplicar la bater&#237;a de corticoides si dichos marcadores son negativos&#46; La bater&#237;a de corticoides y los propios f&#225;rmacos aportados por los pacientes fueron &#250;tiles para definir mejor los grupos de corticoides que estos no pueden utilizar&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:17 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
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                          "etal" => false
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                        ]
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                        ]
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                    ]
                  ]
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                          ]
                        ]
                      ]
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                        0 => array:2 [
                          "etal" => false
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                            0 => "N&#46; Raison-Peyron"
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                  ]
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                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
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                            0 => "C&#46; Pirker"
                            1 => "A&#46; Misic&#8217;"
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                          ]
                        ]
                      ]
                    ]
                  ]
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                        "tituloSerie" => "Contact Dermatitis"
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                        0 => array:2 [
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                            0 => "L&#46; Stingeni"
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                          ]
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                  ]
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                        ]
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                    ]
                  ]
                ]
              ]
            ]
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                  "contribucion" => array:1 [
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; Rodr&#237;guez-Serna"
                            1 => "J&#46;F&#46; Silvestre"
                            2 => "E&#46; Quecedo"
                            3 => "A&#46; Mart&#237;nez"
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                          ]
                        ]
                      ]
                    ]
                  ]
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Información del artículo
ISSN: 15782190
Idioma original: Inglés
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