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Pápulas eritematosas en la espalda con estructuras costrosas hemorrágicas en el centro. b. Pápulas y placas liquenificadas de tonalidad de eritematosa a púrpura en el aspecto lateral del tronco. c. Pápulas y placas de tonalidad de eritematosa a púrpura en la pierna.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I.N. Durusu, G. Gurel, C. Tokyol" "autores" => array:3 [ 0 => array:2 [ "nombre" => "I.N." "apellidos" => "Durusu" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Gurel" ] 2 => array:2 [ "nombre" => "C." 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"tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "S16" "paginaFinal" => "S17" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Herpes Zoster Ophthalmicus and COVID-19: A Post-COVID-19 Complication or a Coincidence?" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1139 "Ancho" => 755 "Tamanyo" => 146193 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">lesiones cutáneas papulopustulares vesiculares en el lado izquierdo del rostro, sin cruzar la línea media.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Pourazizi, S. Dehghani, B. Abtahi-Naeini" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Pourazizi" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Dehghani" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Abtahi-Naeini" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S000173102100377X?idApp=UINPBA000044" "url" => "/00017310/00000113000000S1/v1_202212200523/S000173102100377X/v1_202212200523/es/main.assets" ] "asociados" => array:1 [ 0 => array:19 [ "pii" => "S000173102100377X" "issn" => "00017310" "doi" => "10.1016/j.ad.2021.10.001" "estado" => "S300" "fechaPublicacion" => "2022-12-01" "aid" => "2790" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2022;113 Supl 1:S16-S17" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Herpes zoster oftálmico y COVID-19: ¿Complicación post-COVID-19 o coincidencia?" 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Pourazizi, S. Dehghani, B. Abtahi-Naeini" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Pourazizi" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Dehghani" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Abtahi-Naeini" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S000173102100377X?idApp=UINPBA000044" "url" => "/00017310/00000113000000S1/v1_202212200523/S000173102100377X/v1_202212200523/es/main.assets" ] ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>" "titulo" => " Herpes Zoster Ophthalmicus and COVID-19: A Post-COVID-19 Complication or a Coincidence?" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor</span>," "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "TS16" "paginaFinal" => "TS17" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M. Pourazizi, S. Dehghani, B. Abtahi-Naeini" "autores" => array:3 [ 0 => array:3 [ "nombre" => "M." "apellidos" => "Pourazizi" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "S." "apellidos" => "Dehghani" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:4 [ "nombre" => "B." "apellidos" => "Abtahi-Naeini" "email" => array:1 [ 0 => "bahareh.abtahi@yahoo.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Pediatric Dermatology Division of Department of Pediatrics, Imam Hossein Children's Hospital, Isfahan University of Medical Sciences, Isfahan, Iran" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran" "etiqueta" => "d" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Herpes zoster oftálmico y COVID-19: ¿Complicación post-COVID-19 o coincidencia?" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1137 "Ancho" => 752 "Tamanyo" => 145063 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Vesicular papulopustular skin lesions on the left side of the face, without crossing the midline.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Following the initial waves of the COVID-19 pandemic, an increasing number of case reports and series from around the world reported a potential association between herpes zoster and COVID-19.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">1,2</span></a> We present a new case of herpes zoster ophthalmicus (HZO) associated with this disease. The case also highlights the increased risk of HZO among both immunocompromised and immunocompetent young patients, which is a cause for concern.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 25-year-old woman presented with a 2-day history of painful papulovesicular skin lesions against an erythematous background. The affected skin was particularly painful to the touch, with an “electric-like” pain accompanied by paresthesia. The patient had experienced some relief from over-the-counter analgesics.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Her medical history was unremarkable except for a recent case of moderate to severe COVID-19, confirmed by spiral computed tomography (CT) of the chest, which showed irregular areas of ground glass opacity in both lungs, compatible with COVID-19 pneumonia. The patient denied similar skin lesions in the past. Her general state of health was good before the onset of symptoms.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Vital signs were normal during the physical examination. Examination of facial skin showed vesicular papulopustular lesions on the left side of the face, not crossing the midline (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). A fluorescein eye stain test showed no signs of corneal involvement. No lesions were observed on the nose or ears, including the external acoustic meatus. The neurologic examination was normal. The patient was diagnosed with HZO and prescribed antiviral therapy and local care for 10 days, which led to a significant improvement in lesions.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Herpes zoster is an opportunistic reactivation of the varicella zoster virus that occurs in patients with a weakened immune system. Older age is one of the main risk factors, particularly in immunocompetent patients.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">3,4</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Our patient was a young woman with no clear or classic risk factors for HZO or associated conditions, except for a moderate to severe COVID-19 infection several weeks earlier.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Although herpes zoster in a patient with a history of COVID-19 may be a coincidence in certain cases, it has been hypothesized that SARS-CoV 2 infection might be linked to reactivation of herpes zoster in immunocompetent patients with a history of moderate to severe COVID-19. Potential mechanisms underlying the pathophysiology of herpes zoster reactivation after acute COVID-19 include T cell immune dysfunction,<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">2</span></a> immunological aberrations, and immune dysregulation due to COVID-19.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">This case report highlights the possibility of concurrent herpes reactivation and SARS-CoV-2 infection. More clinical and epidemiological studies are needed to shed light on this link.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0045" class="elsevierStylePara elsevierViewall">No funding was received for this study.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of Interest</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of Interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1137 "Ancho" => 752 "Tamanyo" => 145063 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Vesicular papulopustular skin lesions on the left side of the face, without crossing the midline.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0025" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Can COVID-19 increase the risk of herpes zoster? A narrative review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Diez-Domingo" 1 => "R. Parikh" 2 => "A.B. Bhavsar" 3 => "E. Cisneros" 4 => "N. McCormick" 5 => "N. Lecrenier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Dermatol Ther" "fecha" => "2021" "paginaInicial" => "1" "paginaFinal" => "8" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0030" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A rare case of varicella-zoster virus reactivation following recovery from COVID-19" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.D. Desai" 1 => "K. Sharma" 2 => "J.V. Patoliya" 3 => "E. Ahadov" 4 => "N.N. Patel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.7759/cureus.12423" "Revista" => array:5 [ "tituloSerie" => "Cureus" "fecha" => "2021" "volumen" => "13" "paginaInicial" => "e12423" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33542871" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0035" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical practice: herpes zoster" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.I. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMcp1302674" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2013" "volumen" => "369" "paginaInicial" => "255" "paginaFinal" => "263" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23863052" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0040" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Disseminated varicella-zoster virus in an immunocompetent adult" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Petrun" 1 => "V. Williams" 2 => "S. Brice" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Dermatol Online J" "fecha" => "2015" "volumen" => "21" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/00017310/00000113000000S1/v1_202212200523/S0001731022008808/v1_202212200523/en/main.assets" "Apartado" => array:4 [ "identificador" => "6160" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Cartas científico-clínicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/00000113000000S1/v1_202212200523/S0001731022008808/v1_202212200523/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731022008808?idApp=UINPBA000044" ]
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