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Images in Dermatology
Facial Vitiligo After SARS-CoV-2 Vaccination
Lesiones faciales de vitíligo tras la administración de la vacuna frente a SARS-CoV-2
M.Á. Flores-Terry
Autor para correspondencia
miguelterry85@hotmail.com

Corresponding author.
, M. García-Arpa, J.L. Santiago-Sánchez Mateo, G. Romero Aguilera
Servicio de Dermatología Médico-Quirúrgica y Venereología, Hospital Quirónsalud Ciudad Real, Ciudad Real, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 39-year-old woman with no relevant past personal or family history presented with facial lesions of 10 days&#8217; duration and mild local pruritus&#46; Physical examination showed depigmented&#44; nonscaling lesions on the cheeks and neck &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; No lesions were observed elsewhere&#46; Direct microscopy with potassium hydroxide was negative and laboratory tests &#40;complete blood count&#44; biochemistry&#44; and autoantibodies&#41; were normal or negative&#46; Histopathologic examination of 1 of the lesions showed an absence of melanocytes &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; The patient reported that the lesions had appeared 1 week after receiving the second dose of the mRNA BNT162&#47;Comirnaty vaccine &#40;Pfizer-BioNtech&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Several types of skin reactions associated with SARS-CoV-2 infection and COVID-19 vaccination have been reported&#44; the latter mostly since vaccination of the wider population began&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">There has been just 1 previous report of vitiligo lesions on the face and it was related to the administration of an mRNA COVID-19 vaccine&#46; We believe that this reaction might be linked to the innate and adaptive immune response&#44; with a key role played by the production of interferon-&#947;&#44; mainly by plasmacytoid dendritic cells&#46; We also believe that these lesions may be a marker of better immune response to SARS-CoV-2 infection&#46;</p></span>"
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ISSN: 00017310
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