Letter to the Editor
Transverse-section Histology for Parallel-Ridge Pattern
Sección histological horizontal para el patron de la cresta
Leído
6147
Vecesse ha leído el artículo
2201
Total PDF
3946
Total HTML
Compartir estadísticas
array:23 [ "pii" => "S0001731010002206" "issn" => "00017310" "doi" => "10.1016/j.ad.2010.02.006" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "121" "copyrightAnyo" => "2010" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2010;101:572" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2638 "formatos" => array:3 [ "EPUB" => 34 "HTML" => 1905 "PDF" => 699 ] ] "itemSiguiente" => array:18 [ "pii" => "S0001731010002218" "issn" => "00017310" "doi" => "10.1016/j.ad.2010.03.001" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "122" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2010;101:573" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2411 "formatos" => array:3 [ "EPUB" => 33 "HTML" => 1772 "PDF" => 606 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">LETTER TO THE EDITOR</span>" "titulo" => "Transverse-section histology for parallel-ridge pattern: reply" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "573" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sección histológica horizontal para el patrón de la cresta: réplica" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "N. Blázquez, I. Fernández-Canedo, R. Fúnez, M. de Troya" "autores" => array:4 [ 0 => array:2 [ "nombre" => "N." "apellidos" => "Blázquez" ] 1 => array:2 [ "nombre" => "I." "apellidos" => "Fernández-Canedo" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Fúnez" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "de Troya" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731010002218?idApp=UINPBA000044" "url" => "/00017310/0000010100000006/v1_201304241250/S0001731010002218/v1_201304241250/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0001731010002358" "issn" => "00017310" "doi" => "10.1016/j.ad.2010.01.012" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "133" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2010;101:569-71" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 8114 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 7016 "PDF" => 1094 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Síndrome de Sneddon asociado a urticaria vasculitis y mutación del factor V Leiden" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "569" "paginaFinal" => "571" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Sneddon Syndrome Associated with Urticarial Vasculitis and Factor V Leiden Mutation" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig3" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 651 "Ancho" => 980 "Tamanyo" => 180480 ] ] "descripcion" => array:1 [ "es" => "<p class="elsevierStyleSimplePara elsevierViewall">Imagen histológica de las lesiones urticarianas mostrando un infiltrado perivascular de linfocitos y neutrófilos con leucocitoclasia (hematoxilina-eosina, ×200).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L. Rodríguez-Pazos, S. Gómez-Bernal, D. Sánchez-Aguilar, M.T. Rodríguez-Granados, J. Toribio" "autores" => array:5 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Rodríguez-Pazos" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Gómez-Bernal" ] 2 => array:2 [ "nombre" => "D." "apellidos" => "Sánchez-Aguilar" ] 3 => array:2 [ "nombre" => "M.T." "apellidos" => "Rodríguez-Granados" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Toribio" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731010002358?idApp=UINPBA000044" "url" => "/00017310/0000010100000006/v1_201304241250/S0001731010002358/v1_201304241250/es/main.assets" ] "asociados" => array:1 [ 0 => array:18 [ "pii" => "S0001731010002218" "issn" => "00017310" "doi" => "10.1016/j.ad.2010.03.001" "estado" => "S300" "fechaPublicacion" => "2010-07-01" "aid" => "122" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2010;101:573" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2411 "formatos" => array:3 [ "EPUB" => 33 "HTML" => 1772 "PDF" => 606 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">LETTER TO THE EDITOR</span>" "titulo" => "Transverse-section histology for parallel-ridge pattern: reply" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "573" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sección histológica horizontal para el patrón de la cresta: réplica" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "N. Blázquez, I. Fernández-Canedo, R. Fúnez, M. de Troya" "autores" => array:4 [ 0 => array:2 [ "nombre" => "N." "apellidos" => "Blázquez" ] 1 => array:2 [ "nombre" => "I." "apellidos" => "Fernández-Canedo" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Fúnez" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "de Troya" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731010002218?idApp=UINPBA000044" "url" => "/00017310/0000010100000006/v1_201304241250/S0001731010002218/v1_201304241250/en/main.assets" ] ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Transverse-section Histology for Parallel-Ridge Pattern" "tieneTextoCompleto" => true "saludo" => "To the Editor:" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "572" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "D. Torchia" "autores" => array:1 [ 0 => array:4 [ "nombre" => "D." "apellidos" => "Torchia" "email" => array:1 [ 0 => "dtorchia@med.miami.edu" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Department of Experimental Pathology & Oncology, University of Florence, Florence, Italy" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sección histological horizontal para el patron de la cresta" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p class="elsevierStylePara elsevierViewall">In a recent issue of <span class="elsevierStyleItalic">Actas Dermo-Sifiliográficas</span> Blázquez et al raise the issue on the opportunity to analyse skin biopsies of acral pigmented lesions featuring a parallel-ridge pattern (PRP) after cutting them perpendicularly to the skin markings so that cristae profundae intermediae are included for sure in the tissue section.<a class="elsevierStyleCrossRef" href="#bib1"><span class="elsevierStyleSup">1</span></a> The Authors conclude that “diagnosis of some suspect pigmented lesions is rendered impossible by the low cellularity of the sample. In such cases, the use of molecular biology techniques would be advisable to detect chromosomal abnormalities associated with acrolentiginous melanoma (…)”.<a class="elsevierStyleCrossRef" href="#bib1"><span class="elsevierStyleSup">1</span></a></p><p class="elsevierStylePara elsevierViewall">I wish to point out that transverse-section histology is a cheap and reliable tool to perform dermatoscopic-histologic correlations of acral pigmented lesions as plans of tissue sectioning are parallel to the skin surface and therefore to dermatoscopic visualization of lesions.<a class="elsevierStyleCrossRefs" href="#bib2"><span class="elsevierStyleSup">2,3</span></a> First, transverse-section histology allows a quick, low-magnification scan of the whole excised specimen. Then, higher magnification and analysis of deeper sections of key or “suspicious” dermatoscopic areas achieve and accurate and unambiguous localization of microanatomical structures. Namely, eccrine ducts are cut perpendicularly to their major axis and therefore appear as round or ovalar sections. Epidermal areas containing rows of epidermal ducts are the cristae profundae intermediae, which can be searched thoroughly for atypical/malignant cells and other features (for example melanin columns as a key of benignity) from the overlying corneum till the underlying dermoepidermal junction and dermis. The apparent issue of calculating tumor thickness can be overcome by summing the thickness of all sections overlying the deepest one at which malignant cells are still detected.</p><p class="elsevierStylePara elsevierViewall">In view of these considerations, I propose the following diagnostic iter for acral pigmented lesions featuring a PRP: a) physical examination (possibly with the “furrow-ink test”.<a class="elsevierStyleCrossRef" href="#bib4"><span class="elsevierStyleSup">4</span></a>); b) dermatoscopy; c) wide excisional biopsy; d) split of the specimen into two halves obtained with a cut which is parallel to the skin markings; e) histological examination of half-lesion with sections cut perpendicularly to the skin markings. If no findings of melanoma are present, then f) the remaining half of the specimen should be analyzed after transverse sectioning.</p><p class="elsevierStylePara elsevierViewall">It is worth reaffirming here, though, that the specificity of PRP as a marker of acral lentiginous melanoma is very high<a class="elsevierStyleCrossRef" href="#bib5"><span class="elsevierStyleSup">5</span></a> and that only a handful of PRP-featuring, benign lesions (either pigmented or nonpigmented) have been reported.<a class="elsevierStyleCrossRefs" href="#bib5"><span class="elsevierStyleSup">5–8</span></a> Therefore every lesion showing a PRP should be managed as a melanoma unless top-qualified professionals decide otherwise.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patrón paralelo de la cresta en melanoma acral: importancia del procesamiento de la pieza para el diagnóstico histológico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Blázquez" 1 => "I. Fernández-Canedo" 2 => "R. Fúnez" 3 => "M. de Troya" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2009" "volumen" => "100" "paginaInicial" => "626" "paginaFinal" => "629" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19715655" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fibrillar pattern of a plantar acquired melanocytic naevus: correspondence between epiluminescence microscopy and transverse section histology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G.M. Palleschi" 1 => "E.M. Cipollini" 2 => "D. Torchia" 3 => "E. Torre" 4 => "C. Urso" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2230.2006.02060.x" "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol" "fecha" => "2006" "volumen" => "31" "paginaInicial" => "449" "paginaFinal" => "451" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16681598" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histopathological correlates of the parallel-furrow pattern seen in acral melanocytic nevi at dermatoscopy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G.M. Palleschi" 1 => "C. Urso" 2 => "E. Torre" 3 => "D. Torchia" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000156085" "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "2008" "volumen" => "217" "paginaInicial" => "356" "paginaFinal" => "358" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18802351" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The furrow ink test: a clue for the dermoscopic diagnosis of acral melanoma vs nevus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.P. Braun" 1 => "L. Thomas" 2 => "I. Kolm" 3 => "L.E. French" 4 => "A.A. Marghoob" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archderm.144.12.1618" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2008" "volumen" => "144" "paginaInicial" => "1618" "paginaFinal" => "1620" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19075144" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Significance of dermoscopic patterns in detecting malignant melanoma on acral volar skin: results of a multicenter study in Japan" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Saida" 1 => "A. Miyazaki" 2 => "S. Oguchi" 3 => "Y. Ishihara" 4 => "Y. Yamazaki" 5 => "S. Murase" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archderm.140.10.1233" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2004" "volumen" => "140" "paginaInicial" => "1233" "paginaFinal" => "1238" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15492186" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical melanosis of the foot showing a dermoscopic feature of the parallel ridge pattern" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I. Kilinc Karaarslan" 1 => "T. Akalin" 2 => "I. Unal" 3 => "F. Ozdemir" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1346-8138.2007.00217.x" "Revista" => array:6 [ "tituloSerie" => "J Dermatol" "fecha" => "2007" "volumen" => "34" "paginaInicial" => "56" "paginaFinal" => "59" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17204103" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopy of a plantar combined blue nevus: a simulator of melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V. Panasiti" 1 => "V. Devirgiliis" 2 => "R.G. Borroni" 3 => "M. Mancini" 4 => "M. Rossi" 5 => "M. Curzio" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000098579" "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "2007" "volumen" => "214" "paginaInicial" => "174" "paginaFinal" => "176" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17341869" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acral viral wart showing a parallel ridge pattern on dermatoscopy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N. Arpaia" 1 => "R. Filotico" 2 => "V. Mastrandrea" 3 => "N. Cassano" 4 => "G.A. Vena" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1684/ejd.2009.0670" "Revista" => array:6 [ "tituloSerie" => "Eur J Dermatol" "fecha" => "2009" "volumen" => "19" "paginaInicial" => "381" "paginaFinal" => "382" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19451047" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/00017310/0000010100000006/v1_201304241250/S0001731010002206/v1_201304241250/en/main.assets" "Apartado" => array:4 [ "identificador" => "6165" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Cartas al Director" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/0000010100000006/v1_201304241250/S0001731010002206/v1_201304241250/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731010002206?idApp=UINPBA000044" ]
| año/Mes | Html | Total | |
|---|---|---|---|
| 2024 Noviembre | 1 | 8 | 9 |
| 2024 Octubre | 48 | 35 | 83 |
| 2024 Septiembre | 47 | 26 | 73 |
| 2024 Agosto | 61 | 54 | 115 |
| 2024 Julio | 49 | 28 | 77 |
| 2024 Junio | 46 | 24 | 70 |
| 2024 Mayo | 32 | 31 | 63 |
| 2024 Abril | 32 | 19 | 51 |
| 2024 Marzo | 40 | 35 | 75 |
| 2024 Febrero | 36 | 22 | 58 |
| 2024 Enero | 35 | 30 | 65 |
| 2023 Diciembre | 44 | 24 | 68 |
| 2023 Noviembre | 34 | 24 | 58 |
| 2023 Octubre | 47 | 31 | 78 |
| 2023 Septiembre | 64 | 28 | 92 |
| 2023 Agosto | 35 | 33 | 68 |
| 2023 Julio | 49 | 38 | 87 |
| 2023 Junio | 28 | 17 | 45 |
| 2023 Mayo | 20 | 13 | 33 |
| 2023 Abril | 23 | 16 | 39 |
| 2023 Marzo | 26 | 15 | 41 |
| 2023 Febrero | 42 | 16 | 58 |
| 2023 Enero | 38 | 27 | 65 |
| 2022 Diciembre | 30 | 37 | 67 |
| 2022 Noviembre | 39 | 28 | 67 |
| 2022 Octubre | 36 | 27 | 63 |
| 2022 Septiembre | 31 | 31 | 62 |
| 2022 Agosto | 20 | 31 | 51 |
| 2022 Julio | 27 | 32 | 59 |
| 2022 Junio | 35 | 20 | 55 |
| 2022 Mayo | 49 | 23 | 72 |
| 2022 Abril | 40 | 26 | 66 |
| 2022 Marzo | 49 | 54 | 103 |
| 2022 Febrero | 27 | 22 | 49 |
| 2022 Enero | 42 | 48 | 90 |
| 2021 Diciembre | 57 | 31 | 88 |
| 2021 Noviembre | 50 | 41 | 91 |
| 2021 Octubre | 44 | 37 | 81 |
| 2021 Septiembre | 36 | 37 | 73 |
| 2021 Agosto | 31 | 20 | 51 |
| 2021 Julio | 30 | 30 | 60 |
| 2021 Junio | 32 | 27 | 59 |
| 2021 Mayo | 31 | 33 | 64 |
| 2021 Abril | 82 | 43 | 125 |
| 2021 Marzo | 45 | 27 | 72 |
| 2021 Febrero | 29 | 25 | 54 |
| 2021 Enero | 27 | 16 | 43 |
| 2020 Diciembre | 26 | 15 | 41 |
| 2020 Noviembre | 16 | 12 | 28 |
| 2020 Octubre | 18 | 7 | 25 |
| 2020 Septiembre | 17 | 7 | 24 |
| 2020 Agosto | 24 | 16 | 40 |
| 2020 Julio | 48 | 12 | 60 |
| 2020 Junio | 27 | 24 | 51 |
| 2020 Mayo | 21 | 24 | 45 |
| 2020 Abril | 16 | 20 | 36 |
| 2020 Marzo | 29 | 19 | 48 |
| 2020 Febrero | 3 | 8 | 11 |
| 2020 Enero | 0 | 2 | 2 |
| 2019 Diciembre | 4 | 1 | 5 |
| 2019 Septiembre | 6 | 0 | 6 |
| 2019 Julio | 0 | 5 | 5 |
| 2019 Junio | 0 | 12 | 12 |
| 2019 Mayo | 2 | 35 | 37 |
| 2019 Abril | 2 | 9 | 11 |
| 2019 Marzo | 0 | 5 | 5 |
| 2019 Febrero | 2 | 7 | 9 |
| 2019 Enero | 2 | 0 | 2 |
| 2018 Noviembre | 3 | 0 | 3 |
| 2018 Octubre | 6 | 0 | 6 |
| 2018 Septiembre | 2 | 0 | 2 |
| 2018 Marzo | 1 | 0 | 1 |
| 2018 Febrero | 12 | 4 | 16 |
| 2018 Enero | 16 | 2 | 18 |
| 2017 Diciembre | 36 | 11 | 47 |
| 2017 Noviembre | 12 | 3 | 15 |
| 2017 Octubre | 14 | 1 | 15 |
| 2017 Septiembre | 22 | 7 | 29 |
| 2017 Agosto | 17 | 6 | 23 |
| 2017 Julio | 10 | 2 | 12 |
| 2017 Junio | 31 | 9 | 40 |
| 2017 Mayo | 16 | 4 | 20 |
| 2017 Abril | 23 | 7 | 30 |
| 2017 Marzo | 16 | 7 | 23 |
| 2017 Febrero | 11 | 5 | 16 |
| 2017 Enero | 13 | 6 | 19 |
| 2016 Diciembre | 55 | 4 | 59 |
| 2016 Noviembre | 30 | 9 | 39 |
| 2016 Octubre | 25 | 11 | 36 |
| 2016 Septiembre | 24 | 19 | 43 |
| 2016 Agosto | 37 | 14 | 51 |
| 2016 Julio | 26 | 10 | 36 |
| 2016 Junio | 9 | 20 | 29 |
| 2016 Mayo | 4 | 19 | 23 |
| 2016 Abril | 7 | 2 | 9 |
| 2016 Marzo | 8 | 2 | 10 |
| 2016 Febrero | 6 | 9 | 15 |
| 2016 Enero | 10 | 30 | 40 |
| 2015 Diciembre | 8 | 4 | 12 |
| 2015 Noviembre | 19 | 17 | 36 |
| 2015 Octubre | 18 | 10 | 28 |
| 2015 Septiembre | 6 | 9 | 15 |
| 2015 Agosto | 7 | 4 | 11 |
| 2015 Julio | 32 | 1 | 33 |
| 2015 Junio | 25 | 5 | 30 |
| 2015 Mayo | 39 | 8 | 47 |
| 2015 Abril | 43 | 5 | 48 |
| 2015 Marzo | 31 | 2 | 33 |
| 2015 Febrero | 36 | 0 | 36 |
| 2015 Enero | 34 | 0 | 34 |
| 2014 Diciembre | 29 | 1 | 30 |
| 2014 Noviembre | 25 | 0 | 25 |
| 2014 Octubre | 37 | 1 | 38 |
| 2014 Septiembre | 34 | 1 | 35 |
| 2014 Agosto | 39 | 0 | 39 |
| 2014 Julio | 43 | 3 | 46 |
| 2014 Junio | 41 | 1 | 42 |
| 2014 Mayo | 50 | 1 | 51 |
| 2014 Abril | 36 | 0 | 36 |
| 2014 Marzo | 61 | 20 | 81 |
| 2014 Febrero | 55 | 19 | 74 |
| 2014 Enero | 37 | 21 | 58 |
| 2013 Diciembre | 41 | 20 | 61 |
| 2013 Noviembre | 42 | 18 | 60 |
| 2013 Octubre | 50 | 18 | 68 |
| 2013 Septiembre | 57 | 17 | 74 |
| 2013 Agosto | 40 | 18 | 58 |
| 2013 Julio | 53 | 39 | 92 |
| 2013 Junio | 36 | 22 | 58 |
| 2013 Mayo | 38 | 19 | 57 |
| 2013 Abril | 30 | 24 | 54 |
| 2013 Marzo | 43 | 15 | 58 |
| 2013 Febrero | 25 | 16 | 41 |
| 2013 Enero | 33 | 9 | 42 |
| 2012 Diciembre | 21 | 12 | 33 |
| 2012 Noviembre | 11 | 12 | 23 |
| 2012 Octubre | 7 | 5 | 12 |
| 2012 Agosto | 2 | 1 | 3 |
| 2011 Mayo | 1 | 0 | 1 |
| 2011 Abril | 3 | 0 | 3 |
| 2011 Marzo | 9 | 0 | 9 |
| 2011 Febrero | 8 | 0 | 8 |
| 2011 Enero | 6 | 0 | 6 |
| 2010 Diciembre | 4 | 0 | 4 |
| 2010 Noviembre | 6 | 0 | 6 |
| 2010 Octubre | 5 | 0 | 5 |
| 2010 Septiembre | 15 | 0 | 15 |
| 2010 Agosto | 14 | 0 | 14 |
Mostrar todo
