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        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The introduction of highly active antiretroviral therapy has produced a substantial change in the natural history of human immunodeficiency virus &#40;HIV&#41; infection&#46; The frequency of opportunistic infections and AIDS-related cancers has fallen&#44; though new health problems have developed&#46; Likewise&#44; there has been a change in the spectrum of skin diseases now observed in these patients&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To analyze the prevalence and characteristics of skin disease in a group of HIVinfected outpatients&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A cross-sectional&#44; observational study was performed&#46; All patients who attended the day care unit of the infectious diseases department over a 6-month period &#40;May-October&#44; 2003&#41; were offered the possibility of complete dermatologic examination&#46; Epidemiologic and clinical variables were recorded in all participants&#44; together with the findings on examination of the skin&#46; A comparative study was performed&#44; grouping the patients according to CD4-lymphocyte count and antiretroviral treatment&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The prevalence of dermatoses in the study patients was 98&#46;3&#37;&#46; The most common conditions were xerosis &#40;114 patients&#44; 37&#46;6&#37;&#41;&#44; seborrheic dermatitis &#40;94 patients&#44; 31&#37;&#41;&#44; distal subungual onychomycosis &#40;80 patients&#44; 26&#46;4&#37;&#41;&#44; and viral warts &#40;65 patients&#44; 21&#46;4&#37;&#41;&#46; Grouped by etiology&#44; infectious diseases were the most common &#40;68&#46;6&#37;&#41;&#44; followed by inflammatory diseases &#40;47&#46;5&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Mucocutaneous lesions continue to be very common in HIV-infected patients&#44; although there has been a qualitative change in the conditions that these patients present&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La introducci&#243;n del tratamiento antirretroviral de gran actividad &#40;TARGA&#41; ha supuesto un cambio profundo en la historia natural de la infecci&#243;n por VIH&#46; Las infecciones oportunistas y las neoplasias asociadas a sida han visto reducida su frecuencia&#44; a la vez que han dado paso a nuevos problemas de salud&#46; De igual manera&#44; el espectro de la patolog&#237;a cut&#225;nea que actualmente observamos en estos pacientes se ha visto modificado&#46;</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Analizar la prevalencia y caracter&#237;sticas de la patolog&#237;a cut&#225;nea en una serie de pacientes ambulatorios con infecci&#243;n por VIH&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudio transversal&#44; observacional&#46; A todos los pacientes que acudieron al Hospital de D&#237;a de la Unidad de Enfermedades Infecciosas durante un periodo de seis meses &#40;mayo-octubre 2003&#41; se les ofreci&#243; la posibilidad de la realizaci&#243;n de un examen dermatol&#243;gico completo&#46; Se registraron las variables epidemiol&#243;gicas y cl&#237;nicas de todos los participantes y los hallazgos de la exploraci&#243;n cut&#225;nea&#46; Los pacientes fueron estudiados comparativamente seg&#250;n su recuento de linfocitos CD4 y si realizaban o no tratamiento antirretroviral&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">La frecuencia de dermatosis en los pacientes del estudio fue del 98&#44;3&#37;&#46; Las entidades m&#225;s frecuentes fueron&#58; xerosis &#40;114 pacientes&#44; 37&#44;6&#37;&#41;&#59; dermatitis seborreica &#40;94 pacientes&#44; 31&#37;&#41;&#59; onicomicosis subungueal distal &#40;80 pacientes&#44; 26&#44;4&#37;&#41; y verrugas vulgares &#40;65 pacientes&#44; 21&#44;4&#37;&#41;&#46; Agrupadas por categor&#237;as&#44; la patolog&#237;a infecciosa fue la m&#225;s frecuente &#40;68&#44;6&#37;&#41;&#44; seguida de la patolog&#237;a inflamatoria &#40;47&#44;5&#37;&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Las lesiones cut&#225;neo-mucosas contin&#250;an siendo muy frecuentes en los pacientes con infecci&#243;n por VIH&#44; aunque se ha producido un cambio cualitativo en la patolog&#237;a que presentan&#46;</p>"
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                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Tschachler"
                            1 => "P&#46;R&#46; Bergstresser"
                            2 => "G&#46; Stingl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(96)01032-X"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1996"
                        "volumen" => "348"
                        "paginaInicial" => "659"
                        "paginaFinal" => "663"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8782758"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence and clinical spectrum of skin disease in patients infected with human immunodeficiency virus"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46;M&#46; Coldiron"
                            1 => "P&#46;R&#46; Bergstresser"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1989"
                        "volumen" => "125"
                        "paginaInicial" => "357"
                        "paginaFinal" => "361"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2522293"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of skin manifestations in AIDS patients in the Lome-Tokoin University Hospital &#40;Togo&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46; Pitche"
                            1 => "K&#46; Tchangai-Walla"
                            2 => "G&#46; Napo-Koura"
                            3 => "M&#46; Mijiyawa"
                            4 => "A&#46; Agbere"
                            5 => "A&#46; Tatagan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Sante"
                        "fecha" => "1995"
                        "volumen" => "5"
                        "paginaInicial" => "349"
                        "paginaFinal" => "352"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8784537"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous disease and drug reactions in HIV infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46;A&#46; Coopman"
                            1 => "R&#46;A&#46; Johnson"
                            2 => "R&#46; Platt"
                            3 => "R&#46;S&#46; Stern"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM199306103282304"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "1993"
                        "volumen" => "328"
                        "paginaInicial" => "1670"
                        "paginaFinal" => "1674"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8487826"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of skin disease in HIV infection and its relationship to the degree of immunosuppression"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Uthayakumar"
                            1 => "R&#46; Nandwani"
                            2 => "T&#46; Drinkwater"
                            3 => "A&#46;T&#46; Nayagam"
                            4 => "C&#46;R&#46; Darley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "1997"
                        "volumen" => "137"
                        "paginaInicial" => "595"
                        "paginaFinal" => "598"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9390338"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dermatologic findings associated with human immunodeficiency virus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "W&#46;L&#46; Matis"
                            1 => "A&#46; Triana"
                            2 => "R&#46; Shapiro"
                            3 => "L&#46; Eldred"
                            4 => "B&#46;F&#46; Polk"
                            5 => "A&#46;F&#46; Hood"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1987"
                        "volumen" => "17"
                        "paginaInicial" => "746"
                        "paginaFinal" => "751"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3680653"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalencia de las manifestaciones cut&#225;neas en 159 pacientes infectados por el virus de la inmunodeficiencia humana &#40;VIH&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;P&#46; Garcia-Muret"
                            1 => "R&#46;M&#46; Pujol"
                            2 => "J&#46;L&#46; Barrio"
                            3 => "J&#46; Cadafalch"
                            4 => "J&#46;M&#46; De Moragas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermatosifiliogr"
                        "fecha" => "1988"
                        "volumen" => "79"
                        "paginaInicial" => "651"
                        "paginaFinal" => "655"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Febrer I&#46; &#8220;Lesiones cut&#225;neo-mucosas en la infecci&#243;n por el virus de la inmunodeficiencia humana adquirida&#46; Estudio cl&#237;nico-patol&#243;gico&#8221;&#46; Director&#58; Adolfo Aliaga Boniche&#46; Universidad de Valencia&#44; Departamento de Medicina&#44; 1989&#46;"
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manifestaciones cut&#225;neomucosas en pacientes VIH positivos&#58; Incidencia&#44; correlaci&#243;n cl&#237;nica&#44; inmunol&#243;gica y dermatopatol&#243;gica&#46; Estudio prospectivo de 1161 pacientes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;A&#46; Mu&#241;oz P&#233;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermatosifiliogr"
                        "fecha" => "1999"
                        "volumen" => "90"
                        "paginaInicial" => "11"
                        "paginaFinal" => "20"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Changing morbidity of cutaneous diseases in patients with HIV after the introduction of highly active antiretroviral therapy including a protease inhibitor"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46; Calista"
                            1 => "M&#46; Morri"
                            2 => "A&#46; Stagno"
                            3 => "A&#46; Boschini"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Dermatol"
                        "fecha" => "2002"
                        "volumen" => "3"
                        "paginaInicial" => "59"
                        "paginaFinal" => "62"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11817969"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manifestaciones cut&#225;neas actuales de la infecci&#243;n por VIH"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Almagro"
                            1 => "J&#46; Garc&#237;a"
                            2 => "E&#46; Fonseca"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Piel"
                        "fecha" => "2002"
                        "volumen" => "17"
                        "paginaInicial" => "57"
                        "paginaFinal" => "67"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous manifestations of HIV in the era of highly active antiretroviral therapy&#58; an institutional urban clinic experience"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;C&#46; Zancanaro"
                            1 => "L&#46;Y&#46; McGirt"
                            2 => "A&#46;J&#46; Mamelak"
                            3 => "R&#46;H&#46; Nguyen"
                            4 => "C&#46;R&#46; Martins"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2005.12.030"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2006"
                        "volumen" => "54"
                        "paginaInicial" => "581"
                        "paginaFinal" => "588"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16546578"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lip and oral mucosal lesions in 100 renal transplant recipients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;T&#46; G&#252;le&#231;"
                            1 => "M&#46; Haberal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2009.06.022"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2010"
                        "volumen" => "62"
                        "paginaInicial" => "96"
                        "paginaFinal" => "101"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19926164"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dental health in liver transplant patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46;L&#46; D&#237;az-Ortiz"
                            1 => "J&#46;M&#46; Mic&#243;-Llorens"
                            2 => "J&#46; Gargallo-Albiol"
                            3 => "C&#46; Baliellas-Comellas"
                            4 => "L&#46; Berini-Ayt&#233;s"
                            5 => "C&#46; Gay-Escoda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Oral Patol Oral Cir Bucal"
                        "fecha" => "2005"
                        "volumen" => "10"
                        "paginaInicial" => "66"
                        "paginaFinal" => "72"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
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Vol. 101. Núm. 8.
Páginas 702-709 (octubre 2010)
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Vol. 101. Núm. 8.
Páginas 702-709 (octubre 2010)
Original article
Acceso a texto completo
Current Prevalence and Characteristics of Dermatoses Associated with Human Immunodeficiency Virus Infection
Prevalencia y características de las dermatosis relacionadas con la infección por VIH en la actualidad
Visitas
5684
M. Blanesa,
Autor para correspondencia
blanes_marmar@gva.es

Corresponding author.
, I. Belinchónb, E. Merinoc, J. Portillac, J. Sánchez-Payád, I. Betllochb
a Unidad de Dermatología, Hospital Marina Baixa, Villajoyosa, Alicante, Spain
b Sección de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain
c Unidad de Enfermedades Infecciosas, Hospital General Universitario de Alicante, Alicante, Spain
d Servicio de Medicina Preventiva, Hospital General Universitario de Alicante, Alicante, Spain
Este artículo ha recibido
Información del artículo
Abstract
Introduction

The introduction of highly active antiretroviral therapy has produced a substantial change in the natural history of human immunodeficiency virus (HIV) infection. The frequency of opportunistic infections and AIDS-related cancers has fallen, though new health problems have developed. Likewise, there has been a change in the spectrum of skin diseases now observed in these patients.

Objective

To analyze the prevalence and characteristics of skin disease in a group of HIVinfected outpatients.

Methods

A cross-sectional, observational study was performed. All patients who attended the day care unit of the infectious diseases department over a 6-month period (May-October, 2003) were offered the possibility of complete dermatologic examination. Epidemiologic and clinical variables were recorded in all participants, together with the findings on examination of the skin. A comparative study was performed, grouping the patients according to CD4-lymphocyte count and antiretroviral treatment.

Results

The prevalence of dermatoses in the study patients was 98.3%. The most common conditions were xerosis (114 patients, 37.6%), seborrheic dermatitis (94 patients, 31%), distal subungual onychomycosis (80 patients, 26.4%), and viral warts (65 patients, 21.4%). Grouped by etiology, infectious diseases were the most common (68.6%), followed by inflammatory diseases (47.5%).

Conclusion

Mucocutaneous lesions continue to be very common in HIV-infected patients, although there has been a qualitative change in the conditions that these patients present.

Keywords:
Human immunodeficiency virus
Highly active antiretroviral therapy
Skin disease
Resumen
Introducción

La introducción del tratamiento antirretroviral de gran actividad (TARGA) ha supuesto un cambio profundo en la historia natural de la infección por VIH. Las infecciones oportunistas y las neoplasias asociadas a sida han visto reducida su frecuencia, a la vez que han dado paso a nuevos problemas de salud. De igual manera, el espectro de la patología cutánea que actualmente observamos en estos pacientes se ha visto modificado.

Objetivo

Analizar la prevalencia y características de la patología cutánea en una serie de pacientes ambulatorios con infección por VIH.

Métodos

Estudio transversal, observacional. A todos los pacientes que acudieron al Hospital de Día de la Unidad de Enfermedades Infecciosas durante un periodo de seis meses (mayo-octubre 2003) se les ofreció la posibilidad de la realización de un examen dermatológico completo. Se registraron las variables epidemiológicas y clínicas de todos los participantes y los hallazgos de la exploración cutánea. Los pacientes fueron estudiados comparativamente según su recuento de linfocitos CD4 y si realizaban o no tratamiento antirretroviral.

Resultados

La frecuencia de dermatosis en los pacientes del estudio fue del 98,3%. Las entidades más frecuentes fueron: xerosis (114 pacientes, 37,6%); dermatitis seborreica (94 pacientes, 31%); onicomicosis subungueal distal (80 pacientes, 26,4%) y verrugas vulgares (65 pacientes, 21,4%). Agrupadas por categorías, la patología infecciosa fue la más frecuente (68,6%), seguida de la patología inflamatoria (47,5%).

Conclusiones

Las lesiones cutáneo-mucosas continúan siendo muy frecuentes en los pacientes con infección por VIH, aunque se ha producido un cambio cualitativo en la patología que presentan.

Palabras clave:
Virus de la immunodeficiencia humana
Tratamiento antirretroviral de gran actividad
Dermatosis
El Texto completo está disponible en PDF
References
[1.]
Panel de expertos de Gesida y Plan Nacional sobre el Sida. Recomendaciones de Gesida/Plan Nacional sobre el Sida respecto al tratamiento antirretroviral en adultos infectados por el virus de la inmunodeficiencia humana (Actualización febrero 2009). GESIDA. Producción científica. Recomendaciones y documentos de consenso [online]. 2009. [Accessed 26/9/2009] Available at: http://www.gesida.seimc.org/pcientifica/fuentes/DcyRc/gesidadcyrc2009_RecomendacionesdeGesida-PNSsobreTARVcontextoresaltado.pdf.
[2.]
A. Kreuter, I. Schugt, M. Hartmann, H. Rasokat, P. Altmeyer, N.H. Brockmeyer.
Dermatological diseases and signs of HIV infection.
Eur J Med Res, 7 (2002), pp. 57-62
[3.]
S.C. Remick.
Non-AIDS-defining cancers.
Hematol Oncol Clin North Am, 10 (1996), pp. 1203-1213
[4.]
P. Fernández Peñas, M. Jones Caballero.
Codificacion de las enfermedades dermatologicas. Compatible con la Clasificación Internacional de Enfermedades.
9. a Revisión, Drug Farma, (1996),
[5.]
E. Tschachler, P.R. Bergstresser, G. Stingl.
HIV-related skin diseases.
[6.]
B.M. Coldiron, P.R. Bergstresser.
Prevalence and clinical spectrum of skin disease in patients infected with human immunodeficiency virus.
Arch Dermatol, 125 (1989), pp. 357-361
[7.]
P. Pitche, K. Tchangai-Walla, G. Napo-Koura, M. Mijiyawa, A. Agbere, A. Tatagan.
Prevalence of skin manifestations in AIDS patients in the Lome-Tokoin University Hospital (Togo).
Sante, 5 (1995), pp. 349-352
[8.]
S.A. Coopman, R.A. Johnson, R. Platt, R.S. Stern.
Cutaneous disease and drug reactions in HIV infection.
N Engl J Med, 328 (1993), pp. 1670-1674
[9.]
S. Uthayakumar, R. Nandwani, T. Drinkwater, A.T. Nayagam, C.R. Darley.
The prevalence of skin disease in HIV infection and its relationship to the degree of immunosuppression.
Br J Dermatol, 137 (1997), pp. 595-598
[10.]
W.L. Matis, A. Triana, R. Shapiro, L. Eldred, B.F. Polk, A.F. Hood.
Dermatologic findings associated with human immunodeficiency virus infection.
J Am Acad Dermatol, 17 (1987), pp. 746-751
[11.]
M.P. Garcia-Muret, R.M. Pujol, J.L. Barrio, J. Cadafalch, J.M. De Moragas.
Prevalencia de las manifestaciones cutáneas en 159 pacientes infectados por el virus de la inmunodeficiencia humana (VIH).
Actas Dermatosifiliogr, 79 (1988), pp. 651-655
[12.]
Febrer I. “Lesiones cutáneo-mucosas en la infección por el virus de la inmunodeficiencia humana adquirida. Estudio clínico-patológico”. Director: Adolfo Aliaga Boniche. Universidad de Valencia, Departamento de Medicina, 1989.
[13.]
M.A. Muñoz Pérez.
Manifestaciones cutáneomucosas en pacientes VIH positivos: Incidencia, correlación clínica, inmunológica y dermatopatológica. Estudio prospectivo de 1161 pacientes.
Actas Dermatosifiliogr, 90 (1999), pp. 11-20
[14.]
D. Calista, M. Morri, A. Stagno, A. Boschini.
Changing morbidity of cutaneous diseases in patients with HIV after the introduction of highly active antiretroviral therapy including a protease inhibitor.
Am J Clin Dermatol, 3 (2002), pp. 59-62
[15.]
M. Almagro, J. García, E. Fonseca.
Manifestaciones cutáneas actuales de la infección por VIH.
Piel, 17 (2002), pp. 57-67
[16.]
P.C. Zancanaro, L.Y. McGirt, A.J. Mamelak, R.H. Nguyen, C.R. Martins.
Cutaneous manifestations of HIV in the era of highly active antiretroviral therapy: an institutional urban clinic experience.
J Am Acad Dermatol, 54 (2006), pp. 581-588
[17.]
A.T. Güleç, M. Haberal.
Lip and oral mucosal lesions in 100 renal transplant recipients.
J Am Acad Dermatol, 62 (2010), pp. 96-101
[18.]
M.L. Díaz-Ortiz, J.M. Micó-Llorens, J. Gargallo-Albiol, C. Baliellas-Comellas, L. Berini-Aytés, C. Gay-Escoda.
Dental health in liver transplant patients.
Med Oral Patol Oral Cir Bucal, 10 (2005), pp. 66-72
Copyright © 2010. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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