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Vol. 99. Issue 6.
Pages 477-480 (August 2008)
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Vol. 99. Issue 6.
Pages 477-480 (August 2008)
Case reports
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Pyoderma Gangrenosum Following Cesarean Delivery
Pioderma Gangrenoso Después del Parto por Cesárea
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C. Sanz-Muñoz
Corresponding author
carolsanzm@hotmail.com

Correspondence: C/ Corpus Christi n.° 9, 2.° B, 47005 Valladolid, Spain.
, C. Martínez-Morán, A. Miranda-Romero
Servicio de Dermatología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain
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Abstract

We describe the case of a 30-year-old woman who, 5 days after giving birth to her first child by cesarean section, presented with dehiscence of one end of the surgical wound and a lesion on her leg that developed into a well-defined ulcer; both lesions were very painful. The patient was initially diagnosed with a skin infection and later with superficial pyoderma gangrenosum. The lesions were treated with topical corticosteroids and a good response was observed. No evidence was found of underlying disease. Isolated cases of pyoderma gangrenosum associated with pregnancy or cesarean delivery have been reported in the literature. The etiology of pyoderma gangrenosum is currently unknown, but some theories suggest an immunologic mechanism. Gestation is known to generate a state of immune tolerance that could play a role in the development of the disease and future studies may help to clarify the significance of this association.

Key words:
pyoderma gangrenosum
cesarean section
pregnancy
Resumen

Presentamos el caso de una mujer de 30 años, primípara, que 5 días después del parto por cesárea presenta dehiscencia de uno de los extremos de la herida quirúrgica y una lesión en la pierna, que evolucionó a una úlcera bien constituida, ambas lesiones muy dolorosas. Fue diagnosticada inicialmente de infección cutánea y posteriormente de pioderma gangrenoso superficial; se trataron las lesiones con corticoides tópicos con buena respuesta al tratamiento. Tras el estudio de la paciente no se encontró patología subyacente. La asociación del pioderma gangrenoso con el embarazo o parto por cesárea se encuentra en la literatura como casos individuales. En la actualidad no se conoce la etiología del pioderma gangrenoso, aunque algunas teorías apuntan a un trastorno de la función inmunológica. Se sabe que la gestación determina un estado de inmunotolerancia que podría tener algún papel en el desarrollo del pioderma gangrenoso; futuras investigaciones podrán aclarar la relevancia de esta asociación.

Palabras clave:
pioderma gangrenoso
parto por cesárea
embarazo
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Copyright © 2008. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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