Pigmented or Hemosiderotic Atypical Fibroxanthoma

Pastor-Nieto, M.A.; Kilmurray, L.G.; Requena, L.

doi:10.1016/S1578-2190(09)70070-8

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It affects elderly individuals and presents as irregularly pigmented, dome-shaped nodules or plaques on areas of skin exposed to the sun. We present a case of pigmented atypical fibroxanthoma on the cheek of an 81-year-old man. Six years after excision of the lesion, the patient remains in complete remission, with no signs of residual tumor or metastasis. The 9 cases of pigmented atypical fibroxanthoma reported in the literature are reviewed, and the histopathological features and differential diagnosis are discussed." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "El fibroxantoma atípico pigmentado es una variante rara de fibroxantoma atípico caracterizada por áreas extensas de hemorragia, eritrofagocitosis y depósitos de hemosiderina en el citoplasma de las células neoplásicas. Afecta a pacientes de edad avanzada, y se manifiesta como nódulos cupuliformes o placas pigmentadas, de coloración heterogénea, en áreas de piel fotoexpuesta.Se presenta un caso de fibroxantoma atípico pigmentado de localización malar en un varón de 81 años de edad. Seis años después de la extirpación quirúrgica de la lesión, el paciente permanece en remisión completa, sin que se aprecien signos clínicos de persistencia tumoral o metástasis.Se revisan los 9 casos de fibroxantoma atípico pigmentado publicados en la literatura y se discuten las características histopatológicas y el diagnóstico diferencial de esta rara entidad." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fibroxantoma atípico. 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Abstract

Pigmented atypical fibroxanthoma is a rare variant of atypical fibroxanthoma and is characterized by extensive areas of hemorrhage, erythrophagocytosis, and hemosiderin accumulation in the cytoplasm of the neoplastic cells. It affects elderly individuals and presents as irregularly pigmented, dome-shaped nodules or plaques on areas of skin exposed to the sun. We present a case of pigmented atypical fibroxanthoma on the cheek of an 81-year-old man. Six years after excision of the lesion, the patient remains in complete remission, with no signs of residual tumor or metastasis. The 9 cases of pigmented atypical fibroxanthoma reported in the literature are reviewed, and the histopathological features and differential diagnosis are discussed.

Key words:

atypical fibroxanthoma

pigmented

hemosiderotic

Resumen

El fibroxantoma atípico pigmentado es una variante rara de fibroxantoma atípico caracterizada por áreas extensas de hemorragia, eritrofagocitosis y depósitos de hemosiderina en el citoplasma de las células neoplásicas. Afecta a pacientes de edad avanzada, y se manifiesta como nódulos cupuliformes o placas pigmentadas, de coloración heterogénea, en áreas de piel fotoexpuesta.Se presenta un caso de fibroxantoma atípico pigmentado de localización malar en un varón de 81 años de edad. Seis años después de la extirpación quirúrgica de la lesión, el paciente permanece en remisión completa, sin que se aprecien signos clínicos de persistencia tumoral o metástasis.Se revisan los 9 casos de fibroxantoma atípico pigmentado publicados en la literatura y se discuten las características histopatológicas y el diagnóstico diferencial de esta rara entidad.

Palabras clave:

fibroxantoma atípico

pigmentado

hemosiderótico

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