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                          "autores" => array:4 [
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                            2 => "E&#46;A&#46; Bauer"
                            3 => "A&#46;Z&#46; Eisen"
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                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1980"
                        "volumen" => "3"
                        "paginaInicial" => "271"
                        "paginaFinal" => "279"
                        "link" => array:1 [
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                    0 => array:2 [
                      "titulo" => "Morph&#233;es&#58; classification et prise en charge"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "V&#46; Salmon-Ehr"
                            1 => "C&#46; Eschard"
                            2 => "B&#46; Kalis"
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                        ]
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                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "1998"
                        "volumen" => "125"
                        "paginaInicial" => "283"
                        "paginaFinal" => "290"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9747273"
                            "web" => "Medline"
                          ]
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                      "titulo" => "Disabling pansclerotic morphea of children"
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                          "autores" => array:3 [
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                          ]
                        ]
                      ]
                    ]
                  ]
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                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1980"
                        "volumen" => "116"
                        "paginaInicial" => "169"
                        "paginaFinal" => "173"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7356347"
                            "web" => "Medline"
                          ]
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                    ]
                  ]
                ]
              ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Coexistence of lichen sclerosus&#44; morphea&#44; and lichen planus&#58; report of four cases and review of the literature"
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                        0 => array:2 [
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1985"
                        "volumen" => "12"
                        "paginaInicial" => "844"
                        "paginaFinal" => "851"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4008688"
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                  "contribucion" => array:1 [
                    0 => array:2 [
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                          "autores" => array:3 [
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                            2 => "M&#46; Orizaga"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "1990"
                        "volumen" => "29"
                        "paginaInicial" => "486"
                        "paginaFinal" => "489"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2228375"
                            "web" => "Medline"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Microbiol Inmunol Infect"
                        "fecha" => "2000"
                        "volumen" => "33"
                        "paginaInicial" => "53"
                        "paginaFinal" => "56"
                      ]
                    ]
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                      "titulo" => "Dpenicillamine induced polymyositis and morphea in a woman with Hashimoto thyroiditis"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol"
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                        "paginaInicial" => "538"
                        "paginaFinal" => "539"
                        "link" => array:1 [
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                      "titulo" => "No evidence for Borrelia burgdorferi infection in lesions of morphea and lichen sclerosus et atrophicus in Spain&#46; A prospective study and literature review"
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                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Derm Venereol"
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                        "paginaFinal" => "304"
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                      "titulo" => "Detection of <span class="elsevierStyleItalic">Borrelia burgdorferi</span> DNA &#40;<span class="elsevierStyleItalic">B&#46; garinii</span> or <span class="elsevierStyleItalic">B&#46; afzelii</span>&#41; in morphea and lichen sclerosus et atrophicus tissues of German and Japanese but not of US patients"
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                            0 => "H&#46; Fujiwara"
                            1 => "K&#46; Fujiwara"
                            2 => "K&#46; Hashimoto"
                            3 => "A&#46;H&#46; Mehregan"
                            4 => "G&#46; Schaumburg-Lever"
                            5 => "R&#46; Lange"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1997"
                        "volumen" => "133"
                        "paginaInicial" => "41"
                        "paginaFinal" => "44"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9006371"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Localized scleroderma in adults and children&#46; Clinical and laboratory investigations on 239 cases"
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                          "etal" => true
                          "autores" => array:6 [
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                            2 => "A&#46; Parodi"
                            3 => "A&#46; Borghi"
                            4 => "A&#46; Fuligni"
                            5 => "P&#46; Fabbri"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Dermatol"
                        "fecha" => "2003"
                        "volumen" => "13"
                        "paginaInicial" => "171"
                        "paginaFinal" => "176"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12695134"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lichen sclerosus and eosinophilic fasciitis as manifestations of chronic graft-versus-host disease&#58; expanding the sclerodermoid spectrum"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;V&#46; Schaffer"
                            1 => "J&#46;M&#46; McNiff"
                            2 => "S&#46; Seropian"
                            3 => "D&#46;L&#46; Cooper"
                            4 => "J&#46;L&#46; Bolognia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2005.06.015"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "2005"
                        "volumen" => "53"
                        "paginaInicial" => "591"
                        "paginaFinal" => "601"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16198778"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Liquen escleroatr&#243;fico y morfea"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "G&#46;F&#46; Buezo"
                            1 => "P&#46;F&#46; Pe&#241;as"
                            2 => "J&#46;M&#46; Dorado Bris"
                            3 => "J&#46; Fern&#225;ndez Herrera"
                            4 => "A&#46; Garc&#237;a Diez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr"
                        "fecha" => "1993"
                        "volumen" => "85"
                        "paginaInicial" => "201"
                        "paginaFinal" => "205"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lichen sclerosus et atrophicus is not related to morphea&#46; A clinical and histologic study of 24 patients in whom both conditions were reputed to be present simultaneously"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;A&#46;K&#46; Patterson"
                            1 => "A&#46;B&#46; Ackerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Dermatopathol"
                        "fecha" => "1984"
                        "volumen" => "6"
                        "paginaInicial" => "323"
                        "paginaFinal" => "335"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6388391"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lichen sclerosus et atrophicus&#44; morphea&#44; and coexistence of both diseases&#58; histological studies using lectins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Shono"
                            1 => "M&#46; Amura"
                            2 => "M&#46; Ota"
                            3 => "A&#46; Osaku"
                            4 => "S&#46; Shinomiya"
                            5 => "K&#46; Toda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1991"
                        "volumen" => "127"
                        "paginaInicial" => "1352"
                        "paginaFinal" => "1356"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1716433"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
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Journal Information
Vol. 99. Issue 10.
Pages 808-811 (December 2008)
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Vol. 99. Issue 10.
Pages 808-811 (December 2008)
Case reports
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Patient With Generalized Guttate Morphea and Lichen Sclerosus et Atrophicus
Coexistencia de Morfea en Gotas Generalizada y Liquen Escleroatrófico: A Propósito de un Caso
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9686
B. Blaya
Corresponding author
39144bba@comb.es

Correspondence: Servicio de Dermatología, Hospital de Cruces, Plaza de Cruces s/n, 48903 Barakaldo, Vizcaya, Spain.
, J. Gardeazabal, Z. Martínez de Lagrán, J.L. Díaz-Pérez
Servicio de Dermatología, Hospital de Cruces, Barakaldo, Vizcaya, Spain
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Abstract

Generalized guttate morphea is a very uncommon clinical entity, and few reports are available in the literature. We report the case of a 7-year-old boy who first attended our clinic in 1990 with guttate morphea on the trunk and upper limbs. These lesions were associated with plaque morphea on his right foot. Twelve years later, lesions with a different appearance to the previous ones were observed in the right pectoral region. Clinically and histopathologically, they resembled lichen sclerosus et atrophicus. Given that morphea and lichen sclerosus et atrophicus share certain clinical and pathologic characteristics, some authors believe that these entities may be related or even different presentations of the same disease.

The most noteworthy aspect of our case is the type of morphea, as we were unable to find equivalent examples in the literature.

Key words:
guttate morphea
plaque morphea
scleroderma
lichen sclerosus et atrophicus
Resumen

La morfea en gotas generalizada es una entidad clínica muy poco frecuente, con escasas referencias en la literatura. Describimos el caso de un varón de 7 años que acudió por primera vez a nuestra consulta en 1990 presentando este tipo de morfea en el tronco y las extremidades superiores, asociado a la variante en placas en el pie derecho. Doce años después le aparecieron unas lesiones en la región pectoral derecha de aspecto diferente a las previas, y que resultaron ser características clínica e histopatológicamente de liquen escleroso y atrófico (LEA). La morfea y el LEA comparten algunas características clínico-patológicas, y por ello algunos autores creen que podría tratarse de entidades emparentadas, e incluso de dos presentaciones distintas de una misma enfermedad.

Creemos que lo más llamativo del caso que describimos es el tipo de morfea que presenta, de la que no hemos encontrado ejemplos equiparables en la literatura.

Palabras clave:
morfea en gotas
morfea en placas
esclerodermia
liquen escleroatrófico
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References
[1.]
J. Uitto, D.J. Santa Cruz, E.A. Bauer, A.Z. Eisen.
Morphea and lichen sclerosus et atrophicus.
J Am Acad Dermatol, 3 (1980), pp. 271-279
[2.]
V. Salmon-Ehr, C. Eschard, B. Kalis.
Morphées: classification et prise en charge.
Ann Dermatol Venereol, 125 (1998), pp. 283-290
[3.]
M. Röcken, K. Ghoreschi.
Morfea y liquen escleroso. Dermatología.
1st ed., Elsevier, (2004),
[4.]
J.L. Díaz-Pérez, S.M. Connoly, R.K. Winkelmann.
Disabling pansclerotic morphea of children.
Arch Dermatol, 116 (1980), pp. 169-173
[5.]
M.G. Connelly, R.K. Winkelmann.
Coexistence of lichen sclerosus, morphea, and lichen planus: report of four cases and review of the literature.
J Am Acad Dermatol, 12 (1985), pp. 844-851
[6.]
R. Tremaine, J.E. Adam, M. Orizaga.
Morphea coexisting with lichen sclerosus et atrophicus.
Int J Dermatol, 29 (1990), pp. 486-489
[7.]
K.H. Wu, Y.S. Dai, M.J. Tsai, S.C. Lin, L.H. Wang, M.T. Huang, et al.
Lichen sclerosus et atrophicus, bullous morphea, and systemic lupus erythematosus: a case report.
J Microbiol Inmunol Infect, 33 (2000), pp. 53-56
[8.]
L.A. Dourmishev, S.R. Stomonjakova, A.L. Dourmishev.
Dpenicillamine induced polymyositis and morphea in a woman with Hashimoto thyroiditis.
J Eur Acad Dermatol Venereol, 16 (2002), pp. 538-539
[9.]
J. Alonso-Llamazares, D.H. Persing, P. Anda, L.E. Gibson, B.J. Rutledge, L. Iglesias.
No evidence for Borrelia burgdorferi infection in lesions of morphea and lichen sclerosus et atrophicus in Spain. A prospective study and literature review.
Acta Derm Venereol, 77 (1997), pp. 299-304
[10.]
H. Fujiwara, K. Fujiwara, K. Hashimoto, A.H. Mehregan, G. Schaumburg-Lever, R. Lange, et al.
Detection of Borrelia burgdorferi DNA (B. garinii or B. afzelii) in morphea and lichen sclerosus et atrophicus tissues of German and Japanese but not of US patients.
Arch Dermatol, 133 (1997), pp. 41-44
[11.]
A.V. Marzano, S. Menni, A. Parodi, A. Borghi, A. Fuligni, P. Fabbri, et al.
Localized scleroderma in adults and children. Clinical and laboratory investigations on 239 cases.
Eur J Dermatol, 13 (2003), pp. 171-176
[12.]
J.V. Schaffer, J.M. McNiff, S. Seropian, D.L. Cooper, J.L. Bolognia.
Lichen sclerosus and eosinophilic fasciitis as manifestations of chronic graft-versus-host disease: expanding the sclerodermoid spectrum.
J Am Acad Dermatol, 53 (2005), pp. 591-601
[13.]
G.F. Buezo, P.F. Peñas, J.M. Dorado Bris, J. Fernández Herrera, A. García Diez.
Liquen escleroatrófico y morfea.
Actas Dermosifiliogr, 85 (1993), pp. 201-205
[14.]
J.A.K. Patterson, A.B. Ackerman.
Lichen sclerosus et atrophicus is not related to morphea. A clinical and histologic study of 24 patients in whom both conditions were reputed to be present simultaneously.
Am J Dermatopathol, 6 (1984), pp. 323-335
[15.]
S. Shono, M. Amura, M. Ota, A. Osaku, S. Shinomiya, K. Toda.
Lichen sclerosus et atrophicus, morphea, and coexistence of both diseases: histological studies using lectins.
Arch Dermatol, 127 (1991), pp. 1352-1356
Copyright © 2008. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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