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Vol. 101. Issue 10.
Pages 853-857 (December 2010)
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Vol. 101. Issue 10.
Pages 853-857 (December 2010)
Original Article
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Mohs Micrographic Surgery for the Treatment of Basal Cell Carcinoma
Cirugía micrográfica de Mohs en el tratamiento de carcinoma basocelular
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G. Galimberti
Corresponding author
gaston.galimberti@gmail.com

Corresponding author.
, A. Pontón Montaño, D. Ferrario, A. Kowalczuk, R. Galimberti
Servicio de Dermatología, Escuela de Medicina, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
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Abstract
Introduction

Basal cell carcinoma accounts for 75% of all nonmelanoma skin cancer. Although various treatment modalities are available, the most frequently used option is surgical excision. Here, we evaluate the efficacy of Mohs micrographic surgery for the treatment of basal cell carcinoma.

Material and methods

A retrospective review of cases of basal cell carcinoma treated with Mohs micrographic surgery between October 2003 and June 2009 was performed using patient records from Hospital Italiano in Buenos Aires, Argentina.

Results

A total of 2412 basal cell carcinomas treated with Mohs micrographic surgery were identified; 50.5% were in women and 49.5% in men. The mean age of the patients was 70.7 years (range, 8–100 years). The histologic type of the tumor was solid in 65.3% of cases and in 89% of cases the tumor was located on the head or neck. Ten percent of the tumors were recurrent following previous treatment. A mean of 1.74 Mohs stages were used, with a mean of 3.81 sections. The mean size of the initial defect was 0.86 cm2 and the mean final defect was 1.88 cm2. The ratio of initial tumor size to final defect was estimated at 1.02. Over a mean follow-up of 32 months, there were 9 cases of tumor recurrence (0.37%).

Conclusions

In our experience, Mohs micrographic surgery is effective for the treatment of high-risk basal cell carcinoma.

Keywords:
Mohs micrographic surgery
Basal cell carcinoma
Treatment
Skin cancer
Resumen
Introducción

El carcinoma basocelular constituye el 75% de todos los carcinomas cutáneos no melanoma. Para su tratamiento existen múltiples modalidades siendo la escisión quirúrgica la más frecuentemente usada. Se plantea evaluar la eficacia de la cirugía micrográfica de Mohs en el tratamiento del carcinoma basocelular.

Materiales y métodos

Revisión retrospectiva en la base de datos del Hospital Italiano de Buenos Aires de los casos de carcinoma basocelular tratados con cirugía micrográfica de Mohs entre octubre del 2003 y junio del 2009.

Resultados

Se encontraron 2.412 casos (85,3%); el 50,5% se presentaron en mujeres y el 49,5% en hombres. La media de edad fue de 70,7 años (rango entre 8 y 100 años). El 65,3% de los tumores eran del tipo histológico sólido y la ubicación más frecuente fue la cabeza y el cuello (89%). El 10% de los carcinomas basocelulares eran recidivas de tratamientos previos. El número medio de estadios fue de 1,74 con una media de 3,81 cortes. La media del defecto inicial fue de 0,86 cm2 y del defecto final de 1,88 cm2. La relación defecto final/defecto inicial se estimó en 1,02 cm2. Nueve tumores presentaron recidiva (0,37%) con una media de seguimiento de 32 meses.

Conclusión

Consideramos que la cirugía micrográfica de Mohs es eficaz en el tratamiento del carcinoma basocelular de alto riesgo.

Palabras clave:
Cirugía micrográfica de Mohs
Carcinoma basocelular
Tratamiento
Cáncer de piel
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Copyright © 2010. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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