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Mohs Micrographic Surgery for the Treatment of Basal Cell Carcinoma
Cirugía micrográfica de Mohs en el tratamiento de carcinoma basocelular
G. Galimberti
, A. Pontón Montaño, D. Ferrario, A. Kowalczuk, R. Galimberti
Corresponding author
Servicio de Dermatología, Escuela de Medicina, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
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Encuesta de opinión" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "D. Moreno-Ramírez, E. Fonseca, P. Herranz, M. Ara" "autores" => array:4 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "Moreno-Ramírez" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Fonseca" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Herranz" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Ara" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707332?idApp=UINPBA000044" "url" => "/15782190/0000010100000010/v1_201304241533/S1578219010707332/v1_201304241533/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219010707319" "issn" => "15782190" "doi" => "10.1016/S1578-2190(10)70731-9" "estado" => "S300" "fechaPublicacion" => "2010-12-01" "aid" => "70731" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2010;101:847-52" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2327 "formatos" => array:3 [ "EPUB" => 38 "HTML" => 1455 "PDF" => 834 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "Condom Use and Number of Sexual Partners among Male Syphilis Patients who Report Having Sex with Men" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "847" "paginaFinal" => "852" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Uso de preservativo y número de parejas sexuales en hombres que tienen sexo con hombres con sífilis" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "B. Repiso, M. Frieyro, F. Rivas-Ruiz, M. De Troya" "autores" => array:4 [ 0 => array:2 [ "nombre" => "B." "apellidos" => "Repiso" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Frieyro" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Rivas-Ruiz" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "De Troya" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707319?idApp=UINPBA000044" "url" => "/15782190/0000010100000010/v1_201304241533/S1578219010707319/v1_201304241533/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "Mohs Micrographic Surgery for the Treatment of Basal Cell Carcinoma" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "853" "paginaFinal" => "857" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "G. Galimberti, A. Pontón Montaño, D. Ferrario, A. Kowalczuk, R. Galimberti" "autores" => array:5 [ 0 => array:4 [ "nombre" => "G." "apellidos" => "Galimberti" "email" => array:1 [ 0 => "gaston.galimberti@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Pontón Montaño" ] 2 => array:2 [ "nombre" => "D." "apellidos" => "Ferrario" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Kowalczuk" ] 4 => array:2 [ "nombre" => "R." "apellidos" => "Galimberti" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Escuela de Medicina, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Cirugía micrográfica de Mohs en el tratamiento de carcinoma basocelular" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2010-01-19" "fechaAceptado" => "2010-06-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84829" "palabras" => array:4 [ 0 => "Mohs micrographic surgery" 1 => "Basal cell carcinoma" 2 => "Treatment" 3 => "Skin cancer" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84828" "palabras" => array:4 [ 0 => "Cirugía micrográfica de Mohs" 1 => "Carcinoma basocelular" 2 => "Tratamiento" 3 => "Cáncer de piel" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Basal cell carcinoma accounts for 75% of all nonmelanoma skin cancer. Although various treatment modalities are available, the most frequently used option is surgical excision. Here, we evaluate the efficacy of Mohs micrographic surgery for the treatment of basal cell carcinoma.</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A retrospective review of cases of basal cell carcinoma treated with Mohs micrographic surgery between October 2003 and June 2009 was performed using patient records from Hospital Italiano in Buenos Aires, Argentina.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A total of 2412 basal cell carcinomas treated with Mohs micrographic surgery were identified; 50.5% were in women and 49.5% in men. The mean age of the patients was 70.7 years (range, 8–100 years). The histologic type of the tumor was solid in 65.3% of cases and in 89% of cases the tumor was located on the head or neck. Ten percent of the tumors were recurrent following previous treatment. A mean of 1.74 Mohs stages were used, with a mean of 3.81 sections. The mean size of the initial defect was 0.86 cm<span class="elsevierStyleSup">2</span> and the mean final defect was 1.88 cm<span class="elsevierStyleSup">2</span>. The ratio of initial tumor size to final defect was estimated at 1.02. Over a mean follow-up of 32 months, there were 9 cases of tumor recurrence (0.37%).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">In our experience, Mohs micrographic surgery is effective for the treatment of high-risk basal cell carcinoma.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">El carcinoma basocelular constituye el 75% de todos los carcinomas cutáneos no melanoma. Para su tratamiento existen múltiples modalidades siendo la escisión quirúrgica la más frecuentemente usada. Se plantea evaluar la eficacia de la cirugía micrográfica de Mohs en el tratamiento del carcinoma basocelular.</p> <span class="elsevierStyleSectionTitle">Materiales y métodos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Revisión retrospectiva en la base de datos del Hospital Italiano de Buenos Aires de los casos de carcinoma basocelular tratados con cirugía micrográfica de Mohs entre octubre del 2003 y junio del 2009.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Se encontraron 2.412 casos (85,3%); el 50,5% se presentaron en mujeres y el 49,5% en hombres. La media de edad fue de 70,7 años (rango entre 8 y 100 años). El 65,3% de los tumores eran del tipo histológico sólido y la ubicación más frecuente fue la cabeza y el cuello (89%). El 10% de los carcinomas basocelulares eran recidivas de tratamientos previos. El número medio de estadios fue de 1,74 con una media de 3,81 cortes. La media del defecto inicial fue de 0,86 cm<span class="elsevierStyleSup">2</span> y del defecto final de 1,88 cm<span class="elsevierStyleSup">2</span>. La relación defecto final/defecto inicial se estimó en 1,02 cm<span class="elsevierStyleSup">2</span>. Nueve tumores presentaron recidiva (0,37%) con una media de seguimiento de 32 meses.</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Consideramos que la cirugía micrográfica de Mohs es eficaz en el tratamiento del carcinoma basocelular de alto riesgo.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 5 | 7 | 12 |
| 2024 October | 63 | 36 | 99 |
| 2024 September | 60 | 25 | 85 |
| 2024 August | 81 | 60 | 141 |
| 2024 July | 57 | 34 | 91 |
| 2024 June | 60 | 24 | 84 |
| 2024 May | 51 | 37 | 88 |
| 2024 April | 58 | 32 | 90 |
| 2024 March | 58 | 41 | 99 |
| 2024 February | 39 | 34 | 73 |
| 2024 January | 41 | 40 | 81 |
| 2023 December | 57 | 56 | 113 |
| 2023 November | 40 | 34 | 74 |
| 2023 October | 65 | 31 | 96 |
| 2023 September | 32 | 27 | 59 |
| 2023 August | 32 | 15 | 47 |
| 2023 July | 49 | 36 | 85 |
| 2023 June | 40 | 30 | 70 |
| 2023 May | 53 | 32 | 85 |
| 2023 April | 42 | 21 | 63 |
| 2023 March | 22 | 24 | 46 |
| 2023 February | 28 | 28 | 56 |
| 2023 January | 43 | 24 | 67 |
| 2022 December | 31 | 54 | 85 |
| 2022 November | 16 | 33 | 49 |
| 2022 October | 15 | 14 | 29 |
| 2022 September | 16 | 36 | 52 |
| 2022 August | 10 | 32 | 42 |
| 2022 July | 17 | 21 | 38 |
| 2022 June | 19 | 26 | 45 |
| 2022 May | 30 | 35 | 65 |
| 2022 April | 31 | 35 | 66 |
| 2022 March | 33 | 56 | 89 |
| 2022 February | 21 | 37 | 58 |
| 2022 January | 21 | 49 | 70 |
| 2021 December | 23 | 43 | 66 |
| 2021 November | 28 | 47 | 75 |
| 2021 October | 44 | 54 | 98 |
| 2021 September | 30 | 58 | 88 |
| 2021 August | 27 | 40 | 67 |
| 2021 July | 22 | 40 | 62 |
| 2021 June | 20 | 31 | 51 |
| 2021 May | 32 | 27 | 59 |
| 2021 April | 68 | 72 | 140 |
| 2021 March | 82 | 17 | 99 |
| 2021 February | 61 | 17 | 78 |
| 2021 January | 41 | 19 | 60 |
| 2020 December | 23 | 16 | 39 |
| 2020 November | 22 | 14 | 36 |
| 2020 October | 29 | 14 | 43 |
| 2020 September | 28 | 14 | 42 |
| 2020 August | 26 | 18 | 44 |
| 2020 July | 16 | 10 | 26 |
| 2020 June | 17 | 20 | 37 |
| 2020 May | 23 | 19 | 42 |
| 2020 April | 8 | 12 | 20 |
| 2020 March | 16 | 21 | 37 |
| 2020 February | 2 | 0 | 2 |
| 2020 January | 0 | 5 | 5 |
| 2019 December | 0 | 5 | 5 |
| 2019 November | 0 | 1 | 1 |
| 2019 September | 0 | 2 | 2 |
| 2019 August | 0 | 3 | 3 |
| 2019 July | 0 | 3 | 3 |
| 2019 June | 0 | 10 | 10 |
| 2019 May | 1 | 44 | 45 |
| 2019 April | 0 | 2 | 2 |
| 2019 March | 0 | 4 | 4 |
| 2018 April | 0 | 2 | 2 |
| 2018 March | 1 | 0 | 1 |
| 2018 February | 10 | 3 | 13 |
| 2018 January | 17 | 7 | 24 |
| 2017 December | 14 | 7 | 21 |
| 2017 November | 20 | 8 | 28 |
| 2017 October | 18 | 4 | 22 |
| 2017 September | 6 | 8 | 14 |
| 2017 August | 14 | 8 | 22 |
| 2017 July | 14 | 5 | 19 |
| 2017 June | 15 | 27 | 42 |
| 2017 May | 14 | 16 | 30 |
| 2017 April | 14 | 11 | 25 |
| 2017 March | 12 | 7 | 19 |
| 2017 February | 16 | 8 | 24 |
| 2017 January | 12 | 9 | 21 |
| 2016 December | 23 | 11 | 34 |
| 2016 November | 19 | 7 | 26 |
| 2016 October | 17 | 7 | 24 |
| 2016 September | 23 | 11 | 34 |
| 2016 August | 36 | 9 | 45 |
| 2016 July | 23 | 8 | 31 |
| 2016 June | 11 | 7 | 18 |
| 2016 May | 5 | 8 | 13 |
| 2016 April | 5 | 22 | 27 |
| 2016 March | 3 | 2 | 5 |
| 2016 February | 10 | 2 | 12 |
| 2016 January | 14 | 0 | 14 |
| 2015 December | 9 | 4 | 13 |
| 2015 November | 11 | 2 | 13 |
| 2015 October | 5 | 0 | 5 |
| 2015 September | 3 | 5 | 8 |
| 2015 August | 11 | 7 | 18 |
| 2015 July | 36 | 9 | 45 |
| 2015 June | 27 | 6 | 33 |
| 2015 May | 61 | 18 | 79 |
| 2015 April | 32 | 7 | 39 |
| 2015 March | 26 | 6 | 32 |
| 2015 February | 18 | 7 | 25 |
| 2015 January | 12 | 15 | 27 |
| 2014 December | 37 | 3 | 40 |
| 2014 November | 16 | 6 | 22 |
| 2014 October | 29 | 9 | 38 |
| 2014 September | 26 | 14 | 40 |
| 2014 August | 22 | 13 | 35 |
| 2014 July | 30 | 17 | 47 |
| 2014 June | 36 | 10 | 46 |
| 2014 May | 29 | 21 | 50 |
| 2014 April | 41 | 8 | 49 |
| 2014 March | 35 | 19 | 54 |
| 2014 February | 26 | 15 | 41 |
| 2014 January | 28 | 11 | 39 |
| 2013 December | 30 | 17 | 47 |
| 2013 November | 22 | 18 | 40 |
| 2013 October | 25 | 16 | 41 |
| 2013 September | 27 | 21 | 48 |
| 2013 August | 15 | 17 | 32 |
| 2013 July | 26 | 33 | 59 |
| 2013 June | 23 | 30 | 53 |
| 2013 May | 17 | 17 | 34 |
| 2013 April | 18 | 29 | 47 |
| 2013 March | 22 | 24 | 46 |
| 2013 February | 11 | 12 | 23 |
| 2013 January | 3 | 2 | 5 |
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