Lupus Erythematosus Panniculitis Presenting as Palpebral Edema and Parotiditis

Pérez-Pastor, G.; Valcuende, F.; Tomás, G.; Moreno, M.

doi:10.1016/S1578-2190(07)70511-5

Article information

Abstract

Lupus erythematosus panniculitis or lupus erythematosus profundus is characterized by inflammation of the deep dermis and subcutaneous tissue. It can occur in isolation or associated with chronic systemic or discoid lupus erythematosus. It usually consists of nodules and hardened subcutaneous plaques on the forehead, cheeks, proximal extremities, and buttocks. Periorbital and parotid involvement are rare and can lead to misdiagnosis. We present the case of a patient with lupus erythematosus panniculitis who presented with palpebral edema and involvement of the periocular fat and parotid gland.

Key words:

lupus erythematosus profundus

lupus panniculitis

palpebral

edema

parotid gland

Resumen

La paniculitis lúpica o lupus profundo se caracteriza por la afectación inflamatoria de la dermis profunda y el tejido celular subcutáneo. Puede aparecer de forma aislada o en el contexto de un lupus eritematoso sistémico o discoide crónico. Habitualmente consiste en nódulos y placas subcutáneas induradas localizadas en frente, mejillas, zona proximal de extremidades y nalgas. Otras localizaciones como la periorbitaria y parotídea son muy infrecuentes y pueden llevar a errores diagnósticos. Presentamos el caso de un paciente con paniculitis lúpica con afectación palpebral y de la grasa periocular y periparotídea.

Palabras clave:

lupus profundo

paniculitis lúpica

edema palpebral

parótida

Full text is only aviable in PDF

References

[1]

A.K. Izumi, P. Takiguchi.

Lupus erythematosus panniculitis.

Arch Dermatol, 119 (1983), pp. 61-64

Medline

[2]

T. Watanabe, T. Tsuchida.

Lupus erythematosus profundus: a cutaneous marker for a distinct clinical subset?.

Br J Dermatol, 134 (1996), pp. 123-125

Medline

[3]

D.R. Jordan, H. McDonald, B. Olberg, D. McKim, R. McKendry.

Orbital panniculitis as the initial manifestation of systemic lupus erythematosus.

Ophtalmic Plast Reconstr Surg, 9 (1993), pp. 71-75

[4]

K.L. Magee, S.R. Hymes, R.P. Rapini, J.W. Yeakley, R.E. Jordon.

Lupus erythematosus profundus with periorbital swelling and proptosis.

J Am Acad Dermatol, 24 (1991), pp. 288-290

Medline

[5]

T. Nowinski, V. Bernardino, M. Naidoff, R. Parrish.

Ocular involvement in lupus erythematosus profundus (panniculitis).

Ophthalmology, 89 (1982), pp. 1149-1154

Medline

[6]

W. White, E. Sherertz, D. Berg, R. Clark.

Periparotid lupus erythematosus panniculitis.

Arch Pathol Lab Med, 117 (1993), pp. 535-539

Medline

[7]

N. Ogura, A. Fujisaku, S. Jodo, K. Ichikawa, A. Tsutsumi, M. Mukai, et al.

Lupus erythematosus profundus around the salivary glands: a case resembling submandibular salivary gland disease.

Lupus, 6 (1997), pp. 477-479

Medline

[8]

M. Kaposi.

Pathologie und Therapie der Hautkrankheiten.

2nd ed., Urban & Schwarzenberg, (1883),

[9]

S. Irgang.

Lupus erythematosus profundus: report of an example with clinical resemblance to Darier-Roussy sarcoid.

Arch Dermatol Syph, 42 (1940), pp. 97-108

[10]

Y. Hidalgo, S. Gómez, J.A. Manjón, M. López-Escobar, C. Maldonado, T. Soler, et al.

Paniculitis lúpica en un niño con lupus discoide crónico.

Actas Dermosifiliogr, 95 (2004), pp. 622-625

[11]

P.B. Martens, K.G. Moder, I. Ahmed.

Lupus panniculitis: clinical perspectives from a case series.

J Rheumatol, 26 (1999), pp. 68-72

Medline

[12]

N.P. Sánchez, M.S. Peters, R.K. Winkelmann.

The histopathology of lupus erythematosus panniculitis.

J Am Acad Dermatol, 5 (1981), pp. 673-680

Medline

[13]

N.W. Holland, K. McKnight, V.R. Challa, C.A. Agudelo.

Lupus panniculitis (profundus) involving the breast: report of 2 cases and review of the literature.

J Rheumatol, 22 (1995), pp. 344-346

Medline

[14]

M. Inuzuka, K. Tomita, Y. Tokura, M. Takigawa.

Lupus erythematosus profundus with unusual skin manifestation: subcutaneous nodules coexisting with eyelid plaques.

J Dermatol, 28 (2001), pp. 437-441

Medline

[15]

W. Franke, A. Kuhn, M. Megahed, J. Krutmann, T. Ruzicka, P. Lehmann.

Periorbital edema as the initial symptom of lupus erythematosus profundus. Case report and discusión of the literature.

Hautarzt, 50 (1999), pp. 889-892

Medline

[16]

C. Massone, K. Kodama, W. Salmhofer, R. Abe, H. Shimizu, A. Parodi, et al.

Lupus erythematosus panniculitis (lupus profundus): clinical, histopathological, and molecular analysis of nine cases.

J Cutan Pathol, 32 (2005), pp. 396-404

http://dx.doi.org/10.1111/j.0303-6987.2005.00351.x | Medline

[17]

P.P. Ng, S.H. Tan, T. Tan.

Lupus erythematosus panniculitis: a clinicopathologic study.

Int J Dermatol, 41 (2002), pp. 488-490

Medline

[18]

A. Taieb, J.P. Hehunstre, J. Goetz, J.E. Surlve Bazeille, D. Fizet, G. Hauptmann, et al.

Lupus erythematosus panniculitis with parcial genetic deficiency of C2 and C4 in a child.

Arch Dermatol, 122 (1986), pp. 576-582

Medline

[19]

H. Ujiie, T. Shimizu, M. Ito, K. Arita, H. Shimizu.

Lupus erythematosus profundus successfully treated with dapsone: review of the literature.

Arch Dermatol, 142 (2006), pp. 399-401

http://dx.doi.org/10.1001/archderm.142.3.399 | Medline

Indexed in:

Follow us:

Indexed in:

Follow us:

Subscribe to our newsletter