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            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Schematic representation of Breslow thickness&#44; calculated tumor area&#44; and Breslow density din melanoma&#46;</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; Breslow thickness&#44; mm&#46; B&#44; Calculated tumor area &#40;CTA&#41;&#46; To calculate CTA&#44; construct a box in the Breslow thickness measurement area that includes the entire invasive melanoma and estimate the percentage of the area occupied by invasive cells&#46; Measure the height and width of the box &#40;mm&#41; using the microscope objective lens diameter&#46; The formula for calculating CTA is height&#160;&#215;&#160;width&#160;&#215;&#160;proportion&#46; For example&#44; if the objective measures 5&#160;mm&#44; the box &#40;as shown in the Fig&#46;&#41; measures 3 lenses high and 4 lenses wide&#44; and the area occupied by tumor cells is 20&#37;&#44; the CTA would be 15&#160;&#215;&#160;20&#160;&#215;&#160;20&#47;100&#160;&#61;&#160;60&#160;mm<span class="elsevierStyleSup">2</span>&#46; C&#44; Breslow density&#46; To calculate Breslow density&#44; at the &#215;10 magnification&#44; construct a window in the Breslow measurement area&#44; the bottom of which is limited by the deepest melanoma cell and the top of which is limited by the basement membrane&#46; The width is determined by the width of the magnification field&#46; Horizontally move the window to the area of the dermis with the highest density of melanoma&#44; whilst keeping the deepest melanoma cell within the window&#46; The proportion of the dermis occupied by melanoma cells is expressed with a precision of 5&#37; &#40;for scores &#60;&#160;5&#37; or &#62;&#160;95&#37;&#44; use a precision of 1&#37;&#41;&#46;</p>"
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