array:25 [
  "pii" => "S1578219019303518"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2019.12.002"
  "estado" => "S300"
  "fechaPublicacion" => "2020-01-01"
  "aid" => "2215"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2020;111:76-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1
    "HTML" => 1
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0001731019301802"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2018.05.019"
      "estado" => "S300"
      "fechaPublicacion" => "2020-01-01"
      "aid" => "2215"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2020;111:76-7"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 54
        "formatos" => array:2 [
          "HTML" => 37
          "PDF" => 17
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">CARTA CIENT&#205;FICO-CL&#205;NICA</span>"
        "titulo" => "Papulosis bowenoide lineal"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "76"
            "paginaFinal" => "77"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Linear Bowenoid Papulosis"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1205
                "Ancho" => 905
                "Tamanyo" => 174934
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lesi&#243;n lineal eritematoviol&#225;cea que circunvala el pene&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "F&#46; Allegue, C&#46; Fachal, D&#46; Gonz&#225;lez-Vilas, A&#46; Zulaica"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "F&#46;"
                "apellidos" => "Allegue"
              ]
              1 => array:2 [
                "nombre" => "C&#46;"
                "apellidos" => "Fachal"
              ]
              2 => array:2 [
                "nombre" => "D&#46;"
                "apellidos" => "Gonz&#225;lez-Vilas"
              ]
              3 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Zulaica"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219019303518"
          "doi" => "10.1016/j.adengl.2019.12.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019303518?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301802?idApp=UINPBA000044"
      "url" => "/00017310/0000011100000001/v3_202009190630/S0001731019301802/v3_202009190630/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S1578219019303555"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.12.005"
    "estado" => "S300"
    "fechaPublicacion" => "2020-01-01"
    "aid" => "2224"
    "copyright" => "AEDV"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2020;111:78-80"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Annular Hair Loss and Persistent Crusting in a Baby"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "78"
          "paginaFinal" => "80"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Beb&#233; con alopecia anular y costras persistentes"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1130
              "Ancho" => 1505
              "Tamanyo" => 657197
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histological characteristics &#40;hematoxylin-eosin staining&#41;&#46; A&#44; Sclerotic dermis with dense collagen and a scar-like appearance &#40;original magnification &#215;10&#41;&#46; B&#44; Detail of a broken hair follicle &#40;original magnification &#215;40&#41;&#46; C&#44; Peripheral multinucleated giant cells &#40;original magnification &#215;40&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Mac&#237;as del Toro, M&#46;A&#46; Gonz&#225;lez Domingo, F&#46; Alfageme Rold&#225;n"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Mac&#237;as del Toro"
            ]
            1 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Gonz&#225;lez Domingo"
            ]
            2 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Alfageme Rold&#225;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019301899"
        "doi" => "10.1016/j.ad.2018.06.022"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301899?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019303555?idApp=UINPBA000044"
    "url" => "/15782190/0000011100000001/v2_202004200619/S1578219019303555/v2_202004200619/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S157821901930352X"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.12.003"
    "estado" => "S300"
    "fechaPublicacion" => "2020-01-01"
    "aid" => "2225"
    "copyright" => "AEDV"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2020;111:73-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1
      "HTML" => 1
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Familial Eruptive Pseudoangiomatosis&#58; 2 Recurring Cases"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "73"
          "paginaFinal" => "75"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Pseudoangiomatosis eruptiva familiar&#58; 2 casos de presentaci&#243;n recurrente"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1130
              "Ancho" => 1505
              "Tamanyo" => 205162
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#8211;D&#44; Erythematous-violaceous papular lesions with a peripheral whitish halo in a 7-year-old girl&#46; E&#44; Image of patient 2&#44; showing erythematous lesions on the forearms&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Garc&#237;a-Harana, J&#46; del Boz-Gonz&#225;lez, L&#46; Padilla-Espa&#241;a, S&#46; Rodriguez-Lobalzo, M&#46; de Troya-Mart&#237;n"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Garc&#237;a-Harana"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "del Boz-Gonz&#225;lez"
            ]
            2 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Padilla-Espa&#241;a"
            ]
            3 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Rodriguez-Lobalzo"
            ]
            4 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "de Troya-Mart&#237;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019301905"
        "doi" => "10.1016/j.ad.2018.06.023"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301905?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901930352X?idApp=UINPBA000044"
    "url" => "/15782190/0000011100000001/v2_202004200619/S157821901930352X/v2_202004200619/en/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
    "titulo" => "Linear Bowenoid Papulosis"
    "tieneTextoCompleto" => true
    "saludo" => "<span class="elsevierStyleItalic">To the Editor</span>&#58;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "76"
        "paginaFinal" => "77"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "F Allegue, C Fachal, D Gonz&#225;lez-Vilas, A Zulaica"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "F"
            "apellidos" => "Allegue"
            "email" => array:1 [
              0 => "fallegue@mundo-r.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "C"
            "apellidos" => "Fachal"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "D"
            "apellidos" => "Gonz&#225;lez-Vilas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "A"
            "apellidos" => "Zulaica"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital do Meixoeiro&#44; EOXI&#44; Vigo&#44; Pontevedra&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Anatom&#237;a Patol&#243;gica&#44; Hospital &#193;lvaro Cunqueiro&#44; EOXI&#44; Vigo&#44; Pontevedra&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Papulosis bowenoide lineal"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 682
            "Ancho" => 905
            "Tamanyo" => 262251
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0175"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">p16 immunohistochemistry yields intensely positive results in the cytoplasm and nuclei of keratinocytes throughout the thickness of the epidermis &#40;p16 immunohistochemistry&#44; &#215;200&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Bowenoid papulosis is associated with some types of human papillomavirus &#40;HPV&#41;&#44; mainly type 16&#46; Similar to Bowen disease&#44; histopathology reveals squamous cell carcinoma in situ&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> While the term bowenoid papulosis is not included in the 2016 World Health Organization classification of tumors of the penis&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> the clinical and epidemiological characteristics of the disease and its favorable prognosis lead dermatologists to continue to use the classic nomenclature and consider this condition a differential entity&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Bowenoid papulosis usually manifests as a polygonal planar papular rash on the genital-anal region&#59; however&#44; it may often take on multiple morphologies that should be borne in mind by the physician&#46; We report a case of bowenoid papulosis with an unusual clinical presentation&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The patient was an otherwise healthy 46-year-old uncircumcised man who consulted for a linear lesion on the penis that had first appeared a few weeks previously&#46; He complained of mild pruritus and denied sexual relations outside his habitual partner or injuries in the area&#46; He also denied dysuria or urethral secretion&#46; Physical examination revealed a raised linear lesion that ran parallel to the coronal sulcus along almost all its circumference&#46; It was 1&#8722;2<span class="elsevierStyleHsp" style=""></span>mm wide and erythematous-violaceous in color&#46; The lesion was continuous and seemed to be formed by coalescent papules &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; There were no additional lesions in the genital-anal or oral areas or palpable enlarged lymph nodes&#46; Biopsy revealed an irregularly acanthotic epidermis with hyperkeratosis&#44; parakeratosis&#44; and increased cellularity from the basal layer to the surface&#44; with loss of maturation in all its thickness&#46; The cells were large&#44; occasionally multinucleated&#44; with hyperchromatic nuclei and mitosis in the upper layers of the epidermis &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; p16 immunohistochemistry revealed intense and diffuse nuclear positivity throughout the thickness of the epidermis &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Serology testing for syphilis&#44; hepatitis B and C virus&#44; and human immunodeficiency virus was negative&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The patient was offered various options for therapy and chose a more conservative approach&#46; After receiving the patient&#8217;s consent&#44; we decided to apply topical treatment with sinecatechins 10 &#37; ointment tid&#46; The lesion disappeared completely in 6 weeks&#44; and tolerance of treatment was excellent&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Bowenoid papulosis usually affects young&#44; generally sexually active people between the third and fourth decades of life&#46; The clinical manifestations are polymorphous and comprise macules&#44; papules&#44; and plaques with a flat surface&#46; These are dome-shaped&#44; papillomatous&#44; or verrucous and generally multifocal&#46; While they are frequently pigmented&#44; they may also be erythematous&#44; violaceous&#44; flesh-colored&#44; or leukoplastic&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;3&#8211;5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Clinical presentation in the form of linear lesions is very unusual&#46; Our review yielded only 7 cases&#44;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;5&#8211;8</span></a> thus making the present case the eighth to date&#46; Seven patients were men and only 1 was a woman&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> In men&#44; the lesion tended to affect the coronal sulcus or adjacent area and was circumferential&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;6&#44;7</span></a> Since the lesions usually take the form of coalescent individual lesions&#44; the linear configuration may be continuous or intermittent&#44; with the result that isolated papules are also frequently found close to the linear lesion&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> The case we report is almost identical to that reported by Sweidan et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> in the sense that it involves a single linear&#44; almost filiform lesion in the area of the coronal sulcus with no satellite lesions&#44; thus potentially facilitating the clinical diagnosis&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The mechanism underlying this presentation of bowenoid papulosis is unknown&#44; although it is thought to be associated with a Koebner phenomenon&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Thus&#44; it has been speculated that&#44; since most of these lesions appear close to the coronal sulcus&#44; HPV in the area may be more difficult to eliminate&#44; possibly for anatomical reasons&#46; Therefore&#44; its prolonged persistence in the area could favor this presentation&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Treatment of linear bowenoid papulosis is the same as that of classic disease&#44; which can persist&#44; remit&#44; or recur&#46; Treatment is generally destructive and may comprise conventional surgery&#44; electrocautery&#44; cryotherapy&#44; imiquimod&#44; topical 5-fluorouracil&#44; podophyllin&#44; podophyllotoxin&#44; CO<span class="elsevierStyleInf">2</span> laser therapy&#44; and photodynamic therapy&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Sinecatechins ointment is a standard extract of green tea leaves&#44; which contain a mix of polyphenols with antioxidant&#44; immunostimulatory&#44; antitumor&#44; and antiproliferative properties&#46; It is indicated for genital warts in patients aged &#62;<span class="elsevierStyleHsp" style=""></span>18 years&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> Nonetheless&#44; it is curious that&#44; despite the clear involvement of HPV in the etiology and pathogenesis of bowenoid papulosis&#44; we were able to find only 1 patient treated with this approach&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> The ointment was successful and very well tolerated in the case we report&#44; as in the abovementioned case&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">While we cannot rule out the possibility of spontaneous resolution&#44; which is well documented in bowenoid papulosis&#44; we believe that the treatment we recommended should become standard in this indication&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-02-20"
    "fechaAceptado" => "2018-05-15"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Allegue F&#44; Fachal C&#44; Gonz&#225;lez-Vilas D&#44; Zulaica A&#46; Papulosis bowenoide lineal&#46; Actas Dermosifiliogr&#46; 2020&#59;111&#58;76&#8211;77&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1203
            "Ancho" => 905
            "Tamanyo" => 166252
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0165"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Erythematous-violaceous linear lesion around the penis&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 682
            "Ancho" => 905
            "Tamanyo" => 190988
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0170"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Epidermis with irregular acanthosis&#44; hyperkeratosis&#44; hypergranulosis&#44; and squamous cells&#46; Dyskeratosis&#44; hyperchromatic nuclei&#44; and multiple nuclei can be observed&#46; Cellular atypia is observed throughout the thickness of the epidermis &#40;hematoxylin-eosin&#44; original magnification&#44; &#215;200&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 682
            "Ancho" => 905
            "Tamanyo" => 262251
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0175"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">p16 immunohistochemistry yields intensely positive results in the cytoplasm and nuclei of keratinocytes throughout the thickness of the epidermis &#40;p16 immunohistochemistry&#44; &#215;200&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "&#91;1&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bowenoid papulosis in a linear distribution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "W&#46;S&#46; Peng"
                            1 => "C&#46; Tan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Adv Dermatol Allergol"
                        "fecha" => "2016"
                        "volumen" => "33"
                        "paginaInicial" => "146"
                        "paginaFinal" => "148"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "&#91;2&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A&#58; Renal&#44; Penile&#44; and Testicular Tumours"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "H&#46; Moch"
                            1 => "A&#46;L&#46; Cubilla"
                            2 => "P&#46;A&#46; Humphrey"
                            3 => "V&#46;E&#46; Reuter"
                            4 => "T&#46;M&#46; Ulbright"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.eururo.2016.02.029"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Urol"
                        "fecha" => "2016"
                        "volumen" => "70"
                        "paginaInicial" => "93"
                        "paginaFinal" => "105"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26935559"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "&#91;3&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Les n&#233;oplasies intra-&#233;pith&#233;liales bow&#233;no&#239;des HPV-induites du p&#233;nis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;N&#46; Dauendorffer"
                            1 => "B&#46; Cavelier Balloy"
                            2 => "M&#46; Bagot"
                            3 => "C&#46; Renaud-Vilmer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.annder.2016.12.002"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "2017"
                        "volumen" => "144"
                        "paginaInicial" => "220"
                        "paginaFinal" => "224"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28117082"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0890856709631762"
                          "estado" => "S300"
                          "issn" => "08908567"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "&#91;4&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Linear bowenoid papulosis of the genitalia&#46; A possible Koebner phenomenon"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46;A&#46; Sweidan"
                            1 => "S&#46;M&#46; Salman"
                            2 => "S&#46;T&#46; Zaynoun"
                            3 => "B&#46;A&#46; Sanaknaki"
                            4 => "A&#46;G&#46; Kibbi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4362.1990.tb03830.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "1990"
                        "volumen" => "29"
                        "paginaInicial" => "430"
                        "paginaFinal" => "431"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2397968"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "&#91;5&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple linear bowenoid papulosis without surrounding papules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Kumei"
                            1 => "H&#46; Imanishi"
                            2 => "D&#46; Tsuruta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1346-8138.2011.01468.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Dermatol"
                        "fecha" => "2012"
                        "volumen" => "39"
                        "paginaInicial" => "862"
                        "paginaFinal" => "863"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22221073"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "&#91;6&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multicentric bowen&#8217;s disease of the genitalia&#58; spontaneous regression of lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46;W&#46; Berger"
                            1 => "Y&#46; Hori"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1978"
                        "volumen" => "114"
                        "paginaInicial" => "1698"
                        "paginaFinal" => "1699"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/757959"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "&#91;7&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bowenoid papulosis&#46; A clinicopathologic study with ultrastructural observations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;W&#46; Patterson"
                            1 => "G&#46;F&#46; Kao"
                            2 => "J&#46;H&#46; Graham"
                            3 => "E&#46;B&#46; Helwig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/1097-0142(19860601)57:11<2235::aid-cncr2820571127>3.0.co;2-o"
                      "Revista" => array:4 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1986"
                        "volumen" => "57"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3697922"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "&#91;8&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bowenoid papulosis of the penis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;R&#46; Wade"
                            1 => "A&#46;W&#46; Kopf"
                            2 => "A&#46;B&#46; Ackerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/1097-0142(197810)42:4<1890::aid-cncr2820420430>3.0.co;2-c"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1978"
                        "volumen" => "42"
                        "paginaInicial" => "1890"
                        "paginaFinal" => "1903"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/361215"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "&#91;9&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sinecatechins &#40;polyphenon E&#41; ointment for treatment of external genital warts and posible future indications"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46; Stockfleth"
                            1 => "T&#46; Meyer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Expert Opin Biol Ther"
                        "fecha" => "2014"
                        "volumen" => "14"
                        "paginaInicial" => "1035"
                        "paginaFinal" => "1043"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "&#91;10&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A case report of vulvar carcinoma in situ treated with sinecatechins with complete response"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46; Gupta"
                            1 => "E&#46; Rodr&#237;guez"
                            2 => "V&#46; Andikyan"
                            3 => "S&#46;P&#46; Salob"
                            4 => "D&#46; Chi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.gynor.2013.06.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Gynecologic Oncology Reports"
                        "fecha" => "2013"
                        "volumen" => "6"
                        "paginaInicial" => "10"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24371707"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011100000001/v2_202004200619/S1578219019303518/v2_202004200619/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6157"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case and Research Letters"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011100000001/v2_202004200619/S1578219019303518/v2_202004200619/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019303518?idApp=UINPBA000044"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Case and Research Letters
Linear Bowenoid Papulosis
Papulosis bowenoide lineal
F Alleguea,
Corresponding author
fallegue@mundo-r.com

Corresponding author.
, C Fachalb, D González-Vilasa, A Zulaicaa
a Servicio de Dermatología, Hospital do Meixoeiro, EOXI, Vigo, Pontevedra, Spain
b Servicio de Anatomía Patológica, Hospital Álvaro Cunqueiro, EOXI, Vigo, Pontevedra, Spain
Read
8193
Times
was read the article
2278
Total PDF
5915
Total HTML
Share statistics
 array:25 [
  "pii" => "S1578219019303518"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2019.12.002"
  "estado" => "S300"
  "fechaPublicacion" => "2020-01-01"
  "aid" => "2215"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2019"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2020;111:76-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1
    "HTML" => 1
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0001731019301802"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2018.05.019"
      "estado" => "S300"
      "fechaPublicacion" => "2020-01-01"
      "aid" => "2215"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2020;111:76-7"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 54
        "formatos" => array:2 [
          "HTML" => 37
          "PDF" => 17
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">CARTA CIENT&#205;FICO-CL&#205;NICA</span>"
        "titulo" => "Papulosis bowenoide lineal"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "76"
            "paginaFinal" => "77"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Linear Bowenoid Papulosis"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1205
                "Ancho" => 905
                "Tamanyo" => 174934
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lesi&#243;n lineal eritematoviol&#225;cea que circunvala el pene&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "F&#46; Allegue, C&#46; Fachal, D&#46; Gonz&#225;lez-Vilas, A&#46; Zulaica"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "F&#46;"
                "apellidos" => "Allegue"
              ]
              1 => array:2 [
                "nombre" => "C&#46;"
                "apellidos" => "Fachal"
              ]
              2 => array:2 [
                "nombre" => "D&#46;"
                "apellidos" => "Gonz&#225;lez-Vilas"
              ]
              3 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Zulaica"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219019303518"
          "doi" => "10.1016/j.adengl.2019.12.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019303518?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301802?idApp=UINPBA000044"
      "url" => "/00017310/0000011100000001/v3_202009190630/S0001731019301802/v3_202009190630/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S1578219019303555"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.12.005"
    "estado" => "S300"
    "fechaPublicacion" => "2020-01-01"
    "aid" => "2224"
    "copyright" => "AEDV"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2020;111:78-80"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Annular Hair Loss and Persistent Crusting in a Baby"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "78"
          "paginaFinal" => "80"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Beb&#233; con alopecia anular y costras persistentes"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1130
              "Ancho" => 1505
              "Tamanyo" => 657197
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histological characteristics &#40;hematoxylin-eosin staining&#41;&#46; A&#44; Sclerotic dermis with dense collagen and a scar-like appearance &#40;original magnification &#215;10&#41;&#46; B&#44; Detail of a broken hair follicle &#40;original magnification &#215;40&#41;&#46; C&#44; Peripheral multinucleated giant cells &#40;original magnification &#215;40&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "E&#46; Mac&#237;as del Toro, M&#46;A&#46; Gonz&#225;lez Domingo, F&#46; Alfageme Rold&#225;n"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "E&#46;"
              "apellidos" => "Mac&#237;as del Toro"
            ]
            1 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Gonz&#225;lez Domingo"
            ]
            2 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Alfageme Rold&#225;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019301899"
        "doi" => "10.1016/j.ad.2018.06.022"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301899?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019303555?idApp=UINPBA000044"
    "url" => "/15782190/0000011100000001/v2_202004200619/S1578219019303555/v2_202004200619/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S157821901930352X"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2019.12.003"
    "estado" => "S300"
    "fechaPublicacion" => "2020-01-01"
    "aid" => "2225"
    "copyright" => "AEDV"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2020;111:73-5"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1
      "HTML" => 1
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Familial Eruptive Pseudoangiomatosis&#58; 2 Recurring Cases"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "73"
          "paginaFinal" => "75"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Pseudoangiomatosis eruptiva familiar&#58; 2 casos de presentaci&#243;n recurrente"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1130
              "Ancho" => 1505
              "Tamanyo" => 205162
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#8211;D&#44; Erythematous-violaceous papular lesions with a peripheral whitish halo in a 7-year-old girl&#46; E&#44; Image of patient 2&#44; showing erythematous lesions on the forearms&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Garc&#237;a-Harana, J&#46; del Boz-Gonz&#225;lez, L&#46; Padilla-Espa&#241;a, S&#46; Rodriguez-Lobalzo, M&#46; de Troya-Mart&#237;n"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Garc&#237;a-Harana"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "del Boz-Gonz&#225;lez"
            ]
            2 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Padilla-Espa&#241;a"
            ]
            3 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Rodriguez-Lobalzo"
            ]
            4 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "de Troya-Mart&#237;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731019301905"
        "doi" => "10.1016/j.ad.2018.06.023"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301905?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901930352X?idApp=UINPBA000044"
    "url" => "/15782190/0000011100000001/v2_202004200619/S157821901930352X/v2_202004200619/en/main.assets"
  ]
  "en" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
    "titulo" => "Linear Bowenoid Papulosis"
    "tieneTextoCompleto" => true
    "saludo" => "<span class="elsevierStyleItalic">To the Editor</span>&#58;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "76"
        "paginaFinal" => "77"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "F Allegue, C Fachal, D Gonz&#225;lez-Vilas, A Zulaica"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "F"
            "apellidos" => "Allegue"
            "email" => array:1 [
              0 => "fallegue@mundo-r.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "C"
            "apellidos" => "Fachal"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "D"
            "apellidos" => "Gonz&#225;lez-Vilas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "A"
            "apellidos" => "Zulaica"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital do Meixoeiro&#44; EOXI&#44; Vigo&#44; Pontevedra&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Anatom&#237;a Patol&#243;gica&#44; Hospital &#193;lvaro Cunqueiro&#44; EOXI&#44; Vigo&#44; Pontevedra&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Papulosis bowenoide lineal"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 682
            "Ancho" => 905
            "Tamanyo" => 262251
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0175"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">p16 immunohistochemistry yields intensely positive results in the cytoplasm and nuclei of keratinocytes throughout the thickness of the epidermis &#40;p16 immunohistochemistry&#44; &#215;200&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Bowenoid papulosis is associated with some types of human papillomavirus &#40;HPV&#41;&#44; mainly type 16&#46; Similar to Bowen disease&#44; histopathology reveals squamous cell carcinoma in situ&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> While the term bowenoid papulosis is not included in the 2016 World Health Organization classification of tumors of the penis&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> the clinical and epidemiological characteristics of the disease and its favorable prognosis lead dermatologists to continue to use the classic nomenclature and consider this condition a differential entity&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Bowenoid papulosis usually manifests as a polygonal planar papular rash on the genital-anal region&#59; however&#44; it may often take on multiple morphologies that should be borne in mind by the physician&#46; We report a case of bowenoid papulosis with an unusual clinical presentation&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The patient was an otherwise healthy 46-year-old uncircumcised man who consulted for a linear lesion on the penis that had first appeared a few weeks previously&#46; He complained of mild pruritus and denied sexual relations outside his habitual partner or injuries in the area&#46; He also denied dysuria or urethral secretion&#46; Physical examination revealed a raised linear lesion that ran parallel to the coronal sulcus along almost all its circumference&#46; It was 1&#8722;2<span class="elsevierStyleHsp" style=""></span>mm wide and erythematous-violaceous in color&#46; The lesion was continuous and seemed to be formed by coalescent papules &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; There were no additional lesions in the genital-anal or oral areas or palpable enlarged lymph nodes&#46; Biopsy revealed an irregularly acanthotic epidermis with hyperkeratosis&#44; parakeratosis&#44; and increased cellularity from the basal layer to the surface&#44; with loss of maturation in all its thickness&#46; The cells were large&#44; occasionally multinucleated&#44; with hyperchromatic nuclei and mitosis in the upper layers of the epidermis &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; p16 immunohistochemistry revealed intense and diffuse nuclear positivity throughout the thickness of the epidermis &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Serology testing for syphilis&#44; hepatitis B and C virus&#44; and human immunodeficiency virus was negative&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The patient was offered various options for therapy and chose a more conservative approach&#46; After receiving the patient&#8217;s consent&#44; we decided to apply topical treatment with sinecatechins 10 &#37; ointment tid&#46; The lesion disappeared completely in 6 weeks&#44; and tolerance of treatment was excellent&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Bowenoid papulosis usually affects young&#44; generally sexually active people between the third and fourth decades of life&#46; The clinical manifestations are polymorphous and comprise macules&#44; papules&#44; and plaques with a flat surface&#46; These are dome-shaped&#44; papillomatous&#44; or verrucous and generally multifocal&#46; While they are frequently pigmented&#44; they may also be erythematous&#44; violaceous&#44; flesh-colored&#44; or leukoplastic&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;3&#8211;5</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Clinical presentation in the form of linear lesions is very unusual&#46; Our review yielded only 7 cases&#44;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;5&#8211;8</span></a> thus making the present case the eighth to date&#46; Seven patients were men and only 1 was a woman&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> In men&#44; the lesion tended to affect the coronal sulcus or adjacent area and was circumferential&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;6&#44;7</span></a> Since the lesions usually take the form of coalescent individual lesions&#44; the linear configuration may be continuous or intermittent&#44; with the result that isolated papules are also frequently found close to the linear lesion&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> The case we report is almost identical to that reported by Sweidan et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> in the sense that it involves a single linear&#44; almost filiform lesion in the area of the coronal sulcus with no satellite lesions&#44; thus potentially facilitating the clinical diagnosis&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The mechanism underlying this presentation of bowenoid papulosis is unknown&#44; although it is thought to be associated with a Koebner phenomenon&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Thus&#44; it has been speculated that&#44; since most of these lesions appear close to the coronal sulcus&#44; HPV in the area may be more difficult to eliminate&#44; possibly for anatomical reasons&#46; Therefore&#44; its prolonged persistence in the area could favor this presentation&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">Treatment of linear bowenoid papulosis is the same as that of classic disease&#44; which can persist&#44; remit&#44; or recur&#46; Treatment is generally destructive and may comprise conventional surgery&#44; electrocautery&#44; cryotherapy&#44; imiquimod&#44; topical 5-fluorouracil&#44; podophyllin&#44; podophyllotoxin&#44; CO<span class="elsevierStyleInf">2</span> laser therapy&#44; and photodynamic therapy&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Sinecatechins ointment is a standard extract of green tea leaves&#44; which contain a mix of polyphenols with antioxidant&#44; immunostimulatory&#44; antitumor&#44; and antiproliferative properties&#46; It is indicated for genital warts in patients aged &#62;<span class="elsevierStyleHsp" style=""></span>18 years&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> Nonetheless&#44; it is curious that&#44; despite the clear involvement of HPV in the etiology and pathogenesis of bowenoid papulosis&#44; we were able to find only 1 patient treated with this approach&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> The ointment was successful and very well tolerated in the case we report&#44; as in the abovementioned case&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">While we cannot rule out the possibility of spontaneous resolution&#44; which is well documented in bowenoid papulosis&#44; we believe that the treatment we recommended should become standard in this indication&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2018-02-20"
    "fechaAceptado" => "2018-05-15"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Allegue F&#44; Fachal C&#44; Gonz&#225;lez-Vilas D&#44; Zulaica A&#46; Papulosis bowenoide lineal&#46; Actas Dermosifiliogr&#46; 2020&#59;111&#58;76&#8211;77&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1203
            "Ancho" => 905
            "Tamanyo" => 166252
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0165"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Erythematous-violaceous linear lesion around the penis&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 682
            "Ancho" => 905
            "Tamanyo" => 190988
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0170"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Epidermis with irregular acanthosis&#44; hyperkeratosis&#44; hypergranulosis&#44; and squamous cells&#46; Dyskeratosis&#44; hyperchromatic nuclei&#44; and multiple nuclei can be observed&#46; Cellular atypia is observed throughout the thickness of the epidermis &#40;hematoxylin-eosin&#44; original magnification&#44; &#215;200&#41;&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 682
            "Ancho" => 905
            "Tamanyo" => 262251
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0175"
            "detalle" => "Fig&#46; "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">p16 immunohistochemistry yields intensely positive results in the cytoplasm and nuclei of keratinocytes throughout the thickness of the epidermis &#40;p16 immunohistochemistry&#44; &#215;200&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "&#91;1&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bowenoid papulosis in a linear distribution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "W&#46;S&#46; Peng"
                            1 => "C&#46; Tan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Adv Dermatol Allergol"
                        "fecha" => "2016"
                        "volumen" => "33"
                        "paginaInicial" => "146"
                        "paginaFinal" => "148"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "&#91;2&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A&#58; Renal&#44; Penile&#44; and Testicular Tumours"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "H&#46; Moch"
                            1 => "A&#46;L&#46; Cubilla"
                            2 => "P&#46;A&#46; Humphrey"
                            3 => "V&#46;E&#46; Reuter"
                            4 => "T&#46;M&#46; Ulbright"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.eururo.2016.02.029"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Urol"
                        "fecha" => "2016"
                        "volumen" => "70"
                        "paginaInicial" => "93"
                        "paginaFinal" => "105"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26935559"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "&#91;3&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Les n&#233;oplasies intra-&#233;pith&#233;liales bow&#233;no&#239;des HPV-induites du p&#233;nis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;N&#46; Dauendorffer"
                            1 => "B&#46; Cavelier Balloy"
                            2 => "M&#46; Bagot"
                            3 => "C&#46; Renaud-Vilmer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.annder.2016.12.002"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "2017"
                        "volumen" => "144"
                        "paginaInicial" => "220"
                        "paginaFinal" => "224"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28117082"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0890856709631762"
                          "estado" => "S300"
                          "issn" => "08908567"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "&#91;4&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Linear bowenoid papulosis of the genitalia&#46; A possible Koebner phenomenon"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46;A&#46; Sweidan"
                            1 => "S&#46;M&#46; Salman"
                            2 => "S&#46;T&#46; Zaynoun"
                            3 => "B&#46;A&#46; Sanaknaki"
                            4 => "A&#46;G&#46; Kibbi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4362.1990.tb03830.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "1990"
                        "volumen" => "29"
                        "paginaInicial" => "430"
                        "paginaFinal" => "431"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2397968"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "&#91;5&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple linear bowenoid papulosis without surrounding papules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A&#46; Kumei"
                            1 => "H&#46; Imanishi"
                            2 => "D&#46; Tsuruta"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1346-8138.2011.01468.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Dermatol"
                        "fecha" => "2012"
                        "volumen" => "39"
                        "paginaInicial" => "862"
                        "paginaFinal" => "863"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22221073"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "&#91;6&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multicentric bowen&#8217;s disease of the genitalia&#58; spontaneous regression of lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46;W&#46; Berger"
                            1 => "Y&#46; Hori"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1978"
                        "volumen" => "114"
                        "paginaInicial" => "1698"
                        "paginaFinal" => "1699"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/757959"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "&#91;7&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bowenoid papulosis&#46; A clinicopathologic study with ultrastructural observations"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;W&#46; Patterson"
                            1 => "G&#46;F&#46; Kao"
                            2 => "J&#46;H&#46; Graham"
                            3 => "E&#46;B&#46; Helwig"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/1097-0142(19860601)57:11<2235::aid-cncr2820571127>3.0.co;2-o"
                      "Revista" => array:4 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1986"
                        "volumen" => "57"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3697922"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "&#91;8&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bowenoid papulosis of the penis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;R&#46; Wade"
                            1 => "A&#46;W&#46; Kopf"
                            2 => "A&#46;B&#46; Ackerman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/1097-0142(197810)42:4<1890::aid-cncr2820420430>3.0.co;2-c"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1978"
                        "volumen" => "42"
                        "paginaInicial" => "1890"
                        "paginaFinal" => "1903"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/361215"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "&#91;9&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sinecatechins &#40;polyphenon E&#41; ointment for treatment of external genital warts and posible future indications"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46; Stockfleth"
                            1 => "T&#46; Meyer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Expert Opin Biol Ther"
                        "fecha" => "2014"
                        "volumen" => "14"
                        "paginaInicial" => "1035"
                        "paginaFinal" => "1043"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "&#91;10&#93;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A case report of vulvar carcinoma in situ treated with sinecatechins with complete response"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46; Gupta"
                            1 => "E&#46; Rodr&#237;guez"
                            2 => "V&#46; Andikyan"
                            3 => "S&#46;P&#46; Salob"
                            4 => "D&#46; Chi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.gynor.2013.06.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "Gynecologic Oncology Reports"
                        "fecha" => "2013"
                        "volumen" => "6"
                        "paginaInicial" => "10"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24371707"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011100000001/v2_202004200619/S1578219019303518/v2_202004200619/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6157"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case and Research Letters"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011100000001/v2_202004200619/S1578219019303518/v2_202004200619/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019303518?idApp=UINPBA000044"
]
Article information
ISSN: 15782190
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 14 6 20
2024 October 158 54 212
2024 September 197 29 226
2024 August 146 51 197
2024 July 131 32 163
2024 June 127 41 168
2024 May 123 33 156
2024 April 122 19 141
2024 March 152 26 178
2024 February 154 30 184
2024 January 140 45 185
2023 December 418 23 441
2023 November 333 33 366
2023 October 244 51 295
2023 September 107 67 174
2023 August 73 38 111
2023 July 117 64 181
2023 June 85 77 162
2023 May 124 97 221
2023 April 90 43 133
2023 March 112 64 176
2023 February 82 37 119
2023 January 86 37 123
2022 December 94 49 143
2022 November 111 67 178
2022 October 67 62 129
2022 September 61 63 124
2022 August 54 54 108
2022 July 63 56 119
2022 June 44 48 92
2022 May 79 46 125
2022 April 73 50 123
2022 March 102 55 157
2022 February 99 23 122
2022 January 93 62 155
2021 December 73 42 115
2021 November 72 52 124
2021 October 85 58 143
2021 September 75 45 120
2021 August 97 35 132
2021 July 83 32 115
2021 June 65 41 106
2021 May 64 46 110
2021 April 194 44 238
2021 March 179 38 217
2021 February 94 30 124
2021 January 81 20 101
2020 December 64 19 83
2020 November 70 12 82
2020 October 59 10 69
2020 September 67 24 91
2020 August 49 24 73
2020 July 53 20 73
2020 June 35 16 51
2020 May 22 12 34
2020 April 35 17 52
2020 March 22 9 31
2020 February 1 0 1
2020 January 1 0 1
Show all

Follow this link to access the full text of the article

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?