Case and Research Letters
Giant Vascular Eccrine Spiradenoma
Espiradenoma ecrino vascular gigante
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Jorquera Barquero, C. Lara Bohórquez, I. de Alba Rioja" "autores" => array:3 [ 0 => array:4 [ "nombre" => "E." "apellidos" => "Jorquera Barquero" "email" => array:1 [ 0 => "jorroc@aedv.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "C." "apellidos" => "Lara Bohórquez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "I." "apellidos" => "de Alba Rioja" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio Dermatología M-Q y Venereología, Complejo hospitalario de Huelva, Huelva, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Complejo hospitalario de Huelva , Huelva, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Espiradenoma ecrino vascular gigante" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1300 "Ancho" => 975 "Tamanyo" => 435538 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Organoid pattern of cell nests, some of basaloid appearance with hyperchromatic nuclei and others with large clear cytoplasms, separated by fibrous tracts containing abundant dilated and congestive vascular structures (hematoxylin-eosin<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Giant vascular eccrine spiradenoma is a rare variant of eccrine spiradenoma characterized by its size (> 2<span class="elsevierStyleHsp" style=""></span>cm diameter) and high vascularity, a feature that often leads to it being confused with tumors of vascular origin. We present a case of this rare tumor.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 54-year-old woman presented with a tumor that had been present for years, measuring 2.3<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.6<span class="elsevierStyleHsp" style=""></span>cm, located on the medial aspect of the left arm (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). The tumor was a reddish, dome-shaped lesion, ulcerated on one side, and hard to palpation. The patient attended because the mass had increased in size and at some point there had been a small amount of bleeding. Magnetic resonance imaging (MRI) was performed to investigate the clinical suspicion of a tumor of vascular origin. The different projections (sagittal plane on T2; transverse plane on T1, T2, FFE T2, and STIR) showed a mass located in the subcutaneous cellular tissue, which was presumed to be of vascular origin given that it was described as being dependent on and draining into the basilic vein (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). The lesion was mottled and multilobulated. There was no intramuscular component and the surrounding tissues were unchanged. On the basis of these findings, we proceeded to surgical excision and histopathological study. The tumor, situated in the mid-dermis and deep dermis, was composed of several well-demarcated lobules separated by fine bands of fibrous tissue with abundant dilated and congested vascular structures (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). The lobules were arranged in aggregates of cells, some with a basaloid appearance and others with a larger, clearer cytoplasm, arranged in cords, trabeculae, and solid nests with duct-like structures. On immunohistochemical study, most of the cells expressed pan cytokeratins, and the luminal cells expressed carcinoembryonic antigen (CEA).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Spiradenomas are rare benign tumors derived from the inferior portion of eccrine sweat ducts, and they usually develop on the head, neck, trunk, and, less often, the limbs. Their main clinical characteristic is that they are generally painful. Typically, spiradenomas present in patients aged between 15 and 35 years of age and they are usually solitary, although different clinical presentations have been described.</p><p id="par0020" class="elsevierStylePara elsevierViewall">In 1986, Cotton et al<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> described two cases of eccrine spiradenoma that they classified as giant vascular type due to their large size and high vascularity. Since then, to the best of our knowledge, 12 further cases have been described (<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>). The first description referred to a classic spiradenoma, measuring over the established 2<span class="elsevierStyleHsp" style=""></span>cm diameter, with the most salient feature being its high vascularity. Many authors have described this high vascularity as the result of a stromal involution process due to ageing of the lesion.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7,9</span></a> This concept is defended by some authors,<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> but in our case the information supplied by MRI supported the existence of a tributary vessel. This vessel made it easy to mistake the mass for a vascular tumor, and it would also have promoted tumor growth. The most notable feature in this case was the finding of an afferent vessel to the tumor with drainage into the basilic vein, leading the radiologist to suspect a slow flow vascular malformation. Similarly, the marked vascularization of these tumors means that most eccrine spiradenomas are clinically diagnosed as benign or malignant neoplasms of vascular origin. The most important differential diagnoses are angiosarcoma, which expresses endothelial markers such as CD31 and CD34, and chronic expansive hematoma, which presents as an encapsulated tumor filled with blood and neovasculature.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">What was interesting about this case, apart from the rarity of the condition, was the ease with which a giant vascular eccrine spiradenoma could be mistaken for a lesion of vascular origin.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Jorquera Barquero E, Lara Bohórquez C, de Alba Rioja I. Espiradenoma ecrino vascular gigante. Actas Dermosifiliogr. 2015;106:850–852.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 732 "Ancho" => 976 "Tamanyo" => 86522 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A, Cutaneous component with a dome-like pedunculated vascular appearance and ulceration at the superior pole. B, MRI showing an exophytic multilobulated mass with a blood supply from and drainage to the basilic vein (arrow).</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1300 "Ancho" => 975 "Tamanyo" => 435538 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Organoid pattern of cell nests, some of basaloid appearance with hyperchromatic nuclei and others with large clear cytoplasms, separated by fibrous tracts containing abundant dilated and congestive vascular structures (hematoxylin-eosin<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>10).</p>" ] ] 2 => array:7 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Reference \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Age/Sex \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Size, cm \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Anatomic Location \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Clinical Diagnosis \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cotton et al<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">74/male \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Abdomen \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Angiosarcoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">84/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Occipital scalp \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Sebaceous cyst \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Hey et al<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">63/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">3.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>1.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Thigh \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Venous thrombosis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Senol et al<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">60/male \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">3-4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Chest \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Angioma or thrombosis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ko et al<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">56/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Back \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Angiolipoma or neuroma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Yamakoshi et al<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">76/male \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>3.4<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Shoulder \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Not stated \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Kim et al<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">49/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Arm \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Vascular malformation \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Tremezaygues et al<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">81/male \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">1.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.6<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.9 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Forearm \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Not stated \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Hatano et al<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">52/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">3.5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Arm \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Pilomatricoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Krishnan et al<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">31/male \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Chest \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Not stated \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Nokamura et al<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">79/male \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">7<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>7<span class="elsevierStyleHsp" style=""></span>x<span class="elsevierStyleHsp" style=""></span>6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Chest \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Chronic expansive hematoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Moragon Gordon et al \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">60/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Breast \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Not stated \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Our case \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">54/female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">2.3<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>2<span class="elsevierStyleHsp" style=""></span>x<span class="elsevierStyleHsp" style=""></span>2.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Arm \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Hemangioma \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab957401.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Clinical Characteristics of Giant Vascular Eccrine Spiradenomas.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant vascular eccrine spiradenomas: A report of two cases with histology, immunohistology and electron microscopy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D.W.K. Cotton" 1 => "D.N. Slater" 2 => "N. Rooney" 3 => "J.R. Goepel" 4 => "P.M. Mills" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Histopathology" "fecha" => "1986" "volumen" => "10" "paginaInicial" => "1093" "paginaFinal" => "1099" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3023231" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Vascular eccrine giant spiradenoma-A case report with histology and immunohistology of a rare variant of benign sweat gland tumors" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Hey" 1 => "V. Grouls" 2 => "G. Röckelein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Z Hautkr" "fecha" => "1988" "volumen" => "3" "paginaInicial" => "444" "paginaFinal" => "447" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant vascular eccrine spiradenoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M. Senol" 1 => "A. Ozcan" 2 => "S. Sasmaz" 3 => "S. Ozen" 4 => "H. Ciralik" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "1998" "volumen" => "37" "paginaInicial" => "221" "paginaFinal" => "223" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9556114" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant eccrine spiradenoma: Report of a case with immunohistochemical study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.Y. Ko" 1 => "C.W. Lee" 2 => "S.H. Moon" 3 => "K.W. Song" 4 => "C.K. Park" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3346/jkms.2006.21.1.172" "Revista" => array:6 [ "tituloSerie" => "J Korean Med Sci" "fecha" => "2006" "volumen" => "21" "paginaInicial" => "172" "paginaFinal" => "176" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16479087" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A case of giant vascular eccrine spiradenoma with unusual clinical features" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "T. Yamakoshi" 1 => "T. Makino" 2 => "H. Watanabe" 3 => "M. Furuichi" 4 => "K. Matsui" 5 => "T. Shimizu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2230.2008.03122.x" "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol" "fecha" => "2009" "volumen" => "34" "paginaInicial" => "e250" "paginaFinal" => "e251" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19323658" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant vascular eccrine spiradenoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.H. Kim" 1 => "E. Cho" 2 => "J.D. Lee" 3 => "S.H. Cho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann Dermatol" "fecha" => "2011" "volumen" => "19" "paginaInicial" => "197" "paginaFinal" => "200" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential considerations of skin tumors with florid vascularisation: Report of a solitary giant vascular eccrine spiradenoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.L. Tremezaygues" 1 => "C. Pfohler" 2 => "T. Vogt" 3 => "C.S. Muller" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/bcr.05.2011.4187" "Revista" => array:2 [ "tituloSerie" => "BMJ" "fecha" => "2011" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant vascular eccrine spiradenoma mimicking calcifying epithelioma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Hatano" 1 => "T. Kobayashi" 2 => "S. Fukuzumi" 3 => "Y. Shirakashi" 4 => "C. Nishimura" 5 => "H. Gomi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/1346-8138.12254" "Revista" => array:6 [ "tituloSerie" => "J Dermatol" "fecha" => "2013" "volumen" => "40" "paginaInicial" => "853" "paginaFinal" => "854" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23961898" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant vascular eccrine spiradenoma mimicking chronic expanding hematoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "Y. Nakamura" 1 => "Y. Teramot" 2 => "K. Yamada" 3 => "A. Yamamoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dtsch Dermatol Ges" "fecha" => "2014" "volumen" => "10" "paginaInicial" => "908" "paginaFinal" => "910" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Giant vascular eccrine spiradenoma with unusual clinical presentation: A case report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K. Krishnan" 1 => "A. Thomas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Open J Pathol" "fecha" => "2014" "volumen" => "4" "paginaInicial" => "21" "paginaFinal" => "24" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010600000010/v1_201512060022/S157821901500267X/v1_201512060022/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010600000010/v1_201512060022/S157821901500267X/v1_201512060022/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901500267X?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 12 | 8 | 20 |
| 2024 October | 76 | 39 | 115 |
| 2024 September | 111 | 35 | 146 |
| 2024 August | 124 | 53 | 177 |
| 2024 July | 94 | 34 | 128 |
| 2024 June | 96 | 49 | 145 |
| 2024 May | 84 | 39 | 123 |
| 2024 April | 101 | 22 | 123 |
| 2024 March | 65 | 28 | 93 |
| 2024 February | 63 | 38 | 101 |
| 2024 January | 50 | 37 | 87 |
| 2023 December | 64 | 17 | 81 |
| 2023 November | 82 | 31 | 113 |
| 2023 October | 70 | 24 | 94 |
| 2023 September | 73 | 24 | 97 |
| 2023 August | 53 | 21 | 74 |
| 2023 July | 56 | 33 | 89 |
| 2023 June | 55 | 33 | 88 |
| 2023 May | 58 | 24 | 82 |
| 2023 April | 64 | 27 | 91 |
| 2023 March | 48 | 37 | 85 |
| 2023 February | 73 | 21 | 94 |
| 2023 January | 32 | 26 | 58 |
| 2022 December | 52 | 42 | 94 |
| 2022 November | 46 | 24 | 70 |
| 2022 October | 33 | 25 | 58 |
| 2022 September | 21 | 43 | 64 |
| 2022 August | 28 | 30 | 58 |
| 2022 July | 25 | 24 | 49 |
| 2022 June | 23 | 32 | 55 |
| 2022 May | 30 | 39 | 69 |
| 2022 April | 43 | 42 | 85 |
| 2022 March | 38 | 47 | 85 |
| 2022 February | 37 | 41 | 78 |
| 2022 January | 44 | 44 | 88 |
| 2021 December | 39 | 48 | 87 |
| 2021 November | 43 | 42 | 85 |
| 2021 October | 68 | 51 | 119 |
| 2021 September | 40 | 46 | 86 |
| 2021 August | 29 | 33 | 62 |
| 2021 July | 50 | 33 | 83 |
| 2021 June | 28 | 26 | 54 |
| 2021 May | 36 | 35 | 71 |
| 2021 April | 77 | 47 | 124 |
| 2021 March | 70 | 20 | 90 |
| 2021 February | 50 | 24 | 74 |
| 2021 January | 42 | 29 | 71 |
| 2020 December | 43 | 17 | 60 |
| 2020 November | 36 | 32 | 68 |
| 2020 October | 49 | 15 | 64 |
| 2020 September | 30 | 14 | 44 |
| 2020 August | 33 | 24 | 57 |
| 2020 July | 27 | 15 | 42 |
| 2020 June | 31 | 29 | 60 |
| 2020 May | 32 | 17 | 49 |
| 2020 April | 32 | 24 | 56 |
| 2020 March | 32 | 21 | 53 |
| 2020 February | 4 | 9 | 13 |
| 2020 January | 0 | 7 | 7 |
| 2019 September | 0 | 4 | 4 |
| 2019 August | 0 | 9 | 9 |
| 2019 July | 0 | 10 | 10 |
| 2019 June | 0 | 16 | 16 |
| 2019 May | 0 | 34 | 34 |
| 2019 April | 3 | 28 | 31 |
| 2019 March | 4 | 6 | 10 |
| 2019 February | 2 | 3 | 5 |
| 2019 January | 0 | 1 | 1 |
| 2018 December | 2 | 8 | 10 |
| 2018 November | 3 | 0 | 3 |
| 2018 October | 12 | 0 | 12 |
| 2018 September | 8 | 0 | 8 |
| 2018 May | 0 | 2 | 2 |
| 2018 March | 0 | 1 | 1 |
| 2018 February | 75 | 5 | 80 |
| 2018 January | 24 | 5 | 29 |
| 2017 December | 86 | 11 | 97 |
| 2017 November | 22 | 13 | 35 |
| 2017 October | 27 | 9 | 36 |
| 2017 September | 11 | 14 | 25 |
| 2017 August | 23 | 8 | 31 |
| 2017 July | 23 | 15 | 38 |
| 2017 June | 23 | 21 | 44 |
| 2017 May | 21 | 14 | 35 |
| 2017 April | 25 | 20 | 45 |
| 2017 March | 15 | 44 | 59 |
| 2017 February | 21 | 8 | 29 |
| 2017 January | 18 | 9 | 27 |
| 2016 December | 26 | 25 | 51 |
| 2016 November | 30 | 17 | 47 |
| 2016 October | 26 | 13 | 39 |
| 2016 September | 0 | 2 | 2 |
| 2016 August | 0 | 2 | 2 |
| 2016 June | 1 | 2 | 3 |
| 2016 April | 0 | 2 | 2 |
| 2016 March | 0 | 2 | 2 |
| 2016 February | 0 | 10 | 10 |
| 2016 January | 0 | 2 | 2 |
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