was read the article
array:24 [ "pii" => "S1578219013000139" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.02.008" "estado" => "S300" "fechaPublicacion" => "2013-03-01" "aid" => "673" "copyright" => "Elsevier España, S.L. and AEDV" "copyrightAnyo" => "2011" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:170-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 6999 "formatos" => array:3 [ "EPUB" => 48 "HTML" => 5418 "PDF" => 1533 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731012003006" "issn" => "00017310" "doi" => "10.1016/j.ad.2012.02.017" "estado" => "S300" "fechaPublicacion" => "2013-03-01" "aid" => "673" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:170-2" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 11096 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 8686 "PDF" => 2408 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Dermatosis acantolítica papular del área genitocrural: ¿forma localizada de Darier o Hailey-Hailey?" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "170" "paginaFinal" => "172" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Papular Acantholytic Dermatosis in the Genito-Crural Region: A Localized Form of Darier Disease or Hailey-Hailey Disease?" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 750 "Ancho" => 1000 "Tamanyo" => 136264 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Hematoxilina-eosina (x 63): disqueratosis con cuerpos redondos y granos.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.C. Montis-Palos, E. Acebo-Mariñas, B. Catón-Santarén, R. Soloeta-Arechavala" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M.C." "apellidos" => "Montis-Palos" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Acebo-Mariñas" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Catón-Santarén" ] 3 => array:2 [ "nombre" => "R." "apellidos" => "Soloeta-Arechavala" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219013000139" "doi" => "10.1016/j.adengl.2012.02.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013000139?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012003006?idApp=UINPBA000044" "url" => "/00017310/0000010400000002/v1_201304241237/S0001731012003006/v1_201304241237/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219013000140" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.10.004" "estado" => "S300" "fechaPublicacion" => "2013-03-01" "aid" => "753" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:173-4" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2232 "formatos" => array:3 [ "EPUB" => 42 "HTML" => 1514 "PDF" => 676 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Pigmented Fungiform Papillae of the Tongue in Laugier Disease (or Laugier-Hunziker Syndrome)" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "173" "paginaFinal" => "174" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pigmentación de las papilas fungiformes linguales en la enfermedad de Laugier (o síndrome de Laugier-Hunziker)" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F. Urbina, E. Sudy" "autores" => array:2 [ 0 => array:2 [ "nombre" => "F." "apellidos" => "Urbina" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Sudy" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012004838" "doi" => "10.1016/j.ad.2012.10.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012004838?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013000140?idApp=UINPBA000044" "url" => "/15782190/0000010400000002/v1_201304241618/S1578219013000140/v1_201304241618/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219013000127" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.02.007" "estado" => "S300" "fechaPublicacion" => "2013-03-01" "aid" => "672" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2013;104:168-70" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3119 "formatos" => array:3 [ "EPUB" => 43 "HTML" => 2424 "PDF" => 652 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>" "titulo" => "Allergic Contact Dermatitis Caused by Methyl Aminolevulinate" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "168" "paginaFinal" => "170" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatitis alérgica de contacto a metil aminolevulinato" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1247 "Ancho" => 1667 "Tamanyo" => 207836 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Erythematous, edematous rash with a linear distribution on the lateral aspect of the trunk, limited to the area treated with methyl aminolevulinate cream. There are macular lesions of residual postinflammatory hypopigmentation secondary to segmental Darier disease. The distribution follows the Blaschko lines.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M.A. Pastor-Nieto, E. Jiménez-Blázquez, C. Sánchez-Herreros, P. Belmar-Flores" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M.A." "apellidos" => "Pastor-Nieto" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Jiménez-Blázquez" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Sánchez-Herreros" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "Belmar-Flores" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012002992" "doi" => "10.1016/j.ad.2012.02.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012002992?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013000127?idApp=UINPBA000044" "url" => "/15782190/0000010400000002/v1_201304241618/S1578219013000127/v1_201304241618/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and research letter</span>" "titulo" => "Papular Acantholytic Dermatosis in the Genito-Crural Region: A Localized Form of Darier Disease or Hailey-Hailey Disease?" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "170" "paginaFinal" => "172" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M.C. Montis-Palos, E. Acebo-Mariñas, B. Catón-Santarén, R. Soloeta-Arechavala" "autores" => array:4 [ 0 => array:4 [ "nombre" => "M.C." "apellidos" => "Montis-Palos" "email" => array:1 [ 0 => "mmontis@aedv.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "E." "apellidos" => "Acebo-Mariñas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "B." "apellidos" => "Catón-Santarén" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "R." "apellidos" => "Soloeta-Arechavala" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Santiago, Vitoria, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Santiago, Vitoria, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatosis acantolítica papular del área genitocrural: ¿forma localizada de Darier o Hailey-Hailey?" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1250 "Ancho" => 1667 "Tamanyo" => 329066 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Mild epidermal hyperplasia with hyperkeratosis, parakeratosis, acanthosis, and focal acantholysis with suprabasal clefts. Hematoxylin-eosin, original magnification ×40.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">To the Editor</span>:</p><p id="par0905" class="elsevierStylePara elsevierViewall">Papular acantholytic dyskeratosis (PAD) is a skin condition that typically presents as multiple, small whitish papular lesions that may coalesce into plaques; more rarely it is seen as solitary papules. Involvement of the vulva was first described by Chorzelski et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> in 1984; this form is most frequently observed on the labia majora of middle-aged women with no familial history of the disease. Cases of PAD of the penis, anal canal, and inguinal skin folds have also been reported.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2–4</span></a> The condition is usually asymptomatic, although intense pruritus may develop. Histopathological changes include acantholysis with variable degrees of dyskeratosis, and direct and indirect immunofluorescence have been negative in almost all cases studied.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">We present a 58-year-old woman with no past medical history or family history of interest. She was referred to the dermatology department for pruritic lesions that had developed 2 months earlier in the genital region. She did not report any contact allergies or at-risk sexual activities. Physical examination revealed multiple, shiny whitish papules of 2 to 3<span class="elsevierStyleHsp" style=""></span>mm in diameter in a cobblestone pattern on the medial aspect of the thigh, on the labia majora, on the perineum, and in the perianal region (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). There were no similar lesions on other areas of the skin or mucosas and no nail changes. Laboratory tests (routine blood tests; serology for hepatitis B and C viruses, human immunodeficiency virus, and antinuclear, antibasement membrane, and antidesmoglein 1 and 3 antibodies; and cultures for bacteria and fungi) were normal or negative. Biopsy findings included mild epidermal hyperplasia with hyperkeratosis, parakeratosis, acanthosis, focal acantholysis with suprabasal clefts (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>), and dyskeratosis with corps ronds and grains (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>); a mild perivascular mononuclear inflammatory infiltrate was present in the papillary dermis. Direct immunofluorescence with immunoglobulin (Ig) M, IgG, IgA, complement components C3 and C1q, and fibrinogen antisera was negative. With a diagnosis of PAD of the genitocrural region, treatment was started with topical clobetasol, which produced an improvement in the pruritus, though the lesions persisted.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The main differential diagnosis of PAD is with Hailey-Hailey disease and Darier disease, which are hereditary genodermatoses in which loss of function mutations of the <span class="elsevierStyleItalic">ATP2C1</span> and <span class="elsevierStyleItalic">ATP2A2</span> calcium pump genes, respectively, have been reported in peripheral blood DNA samples. Darier disease, with very similar histopathological findings to those observed in our patient, usually develops in adolescence and is characterized by verrucous papules and plaques in seborrheic regions, with punctate palmoplantar keratoderma, verrucous papules on the dorsum of the hands and the feet, and characteristic nail changes. Hailey-Hailey disease can also show histological similarities with reported cases of PAD but, in contrast to Darier disease, there is a predominance of acantholysis and the dyskeratosis is very mild or absent; the disease typically presents in young adults, with painful erosions in the skin folds. Transient acantholytic dermatosis (Grover disease) should also be included in the differential diagnosis because of its histopathological similarities with PAD, although it typically presents in adults as transient confluent pruritic papules on the trunk.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The individual responses of patients with PAD to treatment with corticosteroids, topical retinoids, cryotherapy, electrocoagulation, or surgery have been reported as variable.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> In a recent study, laser therapy achieved lasting symptomatic improvement.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The issues we have discussed regarding the classification of PAD as a separate entity from Darier or Hailey-Hailey disease arise because there have been reports of cases of Darier and Hailey-Hailey disease localized to the genitocrural region that have been histologically similar to PAD.<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">8,9</span></a> The fact that Hailey-Hailey disease can show a variable degree of penetration and can present at different ages leads to even greater confusion. Two recent publications have reported a mutation in <span class="elsevierStyleItalic">ATP2C1</span> in 3 cases of PAD of the genitocrural area, suggesting that at least some cases of PAD could be localized variants of Hailey-Hailey disease.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4,10</span></a> It was not possible to perform a genetic study in our patient.</p><p id="par0030" class="elsevierStylePara elsevierViewall">In conclusion, we believe that PAD has not yet been fully defined, and that its final characterization will require genetic study to exclude localized Darier or Hailey-Hailey disease, as there may be clinical and histopathological overlap.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: Montis-Palos MC, et al. Dermatosis acantolítica papular del área genitocrural: ¿forma localizada de Darier o Hailey-Hailey? Actas Dermosifiliogr. 2013;104:170–2.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1112 "Ancho" => 1667 "Tamanyo" => 145550 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Multiple, shiny whitish papules of 2 to 3<span class="elsevierStyleHsp" style=""></span>mm in diameter in a cobblestone pattern on the medial aspect of the thigh, on the labia majora, on the perineum, and in the perianal region.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1250 "Ancho" => 1667 "Tamanyo" => 329066 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Mild epidermal hyperplasia with hyperkeratosis, parakeratosis, acanthosis, and focal acantholysis with suprabasal clefts. Hematoxylin-eosin, original magnification ×40.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1250 "Ancho" => 1667 "Tamanyo" => 207804 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Dyskeratosis with corps ronds and grains. Hematoxylin-eosin, original magnification ×63.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is papular acantholytic dyskeratosis of the vulva a new entity?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.P. Chorzelski" 1 => "J. Kudejko" 2 => "S. Jablonska" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "1984" "volumen" => "6" "paginaInicial" => "557" "paginaFinal" => "560" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6524638" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Papular acantholytic dyskeratosis of the penis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.C.J. Van der Putte" 1 => "H.B. Oey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "1986" "volumen" => "8" "paginaInicial" => "365" "paginaFinal" => "366" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3766928" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Focal acantholytic dyskeratosis of the anal canal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.L. Wakel" 1 => "R.M. Jager" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Dermatopathol" "fecha" => "1986" "volumen" => "4" "paginaInicial" => "362" "paginaFinal" => "363" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acantholytic dermatosis of the crural folds with ATP2C1 mutation is a possible variant of Hailey-Hailey disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.B. Lipoff" 1 => "A.V. Mudgil" 2 => "S. Young" 3 => "P. Chu" 4 => "S.R. Cohen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Cutan Med Surg" "fecha" => "2009" "volumen" => "13" "paginaInicial" => "151" "paginaFinal" => "154" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19426624" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acantholytic dermatosis localized to the vulvocrural area" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.H. Cooper" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Cut Pathol" "fecha" => "1989" "volumen" => "16" "paginaInicial" => "81" "paginaFinal" => "84" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Papular acantholytic dyskeratosis of the vulva" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.K. Bell" 1 => "C.W. Farrar" 2 => "R.K. Curley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol" "fecha" => "2001" "volumen" => "26" "paginaInicial" => "386" "paginaFinal" => "388" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11488821" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Successful laser therapy of a papular acantholytic dyskeratosis of the vulva: case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "C.J. Dittmer" 1 => "A. Hornemann" 2 => "C. Rose" 3 => "K. Diedrich" 4 => "M. Thill" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00404-009-1313-8" "Revista" => array:6 [ "tituloSerie" => "Arch Gynecol Obstet" "fecha" => "2010" "volumen" => "281" "paginaInicial" => "723" "paginaFinal" => "725" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20012979" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Placas erosivas y verrugosas en pliegues inguinales" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Chavarria" 1 => "J.M. Hernaz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2005" "volumen" => "96" "paginaInicial" => "703" "paginaFinal" => "705" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16476325" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genital benign chronic pemphigus (Hailey-Hailey disease) presenting as condylomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Langenberg" 1 => "T.G. Berger" 2 => "M. Cardelli" 3 => "O.G. Rodman" 4 => "S. Estes" 5 => "D.R. Barron" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1992" "volumen" => "26" "paginaInicial" => "951" "paginaFinal" => "955" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1607414" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genitoperineal popular acantholytic dyskeratosis is allelic to Hailey-Hailey disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Pernet" 1 => "D. Bessis" 2 => "M. Savignac" 3 => "E. Tron" 4 => "B. Guillot" 5 => "A. Hovnanian" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2012.10810.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2012" "volumen" => "167" "paginaInicial" => "210" "paginaFinal" => "212" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22229453" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010400000002/v1_201304241618/S1578219013000139/v1_201304241618/en/main.assets" "Apartado" => array:4 [ "identificador" => "6157" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010400000002/v1_201304241618/S1578219013000139/v1_201304241618/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219013000139?idApp=UINPBA000044" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 26 | 16 | 42 |
2024 October | 143 | 47 | 190 |
2024 September | 154 | 36 | 190 |
2024 August | 155 | 93 | 248 |
2024 July | 138 | 37 | 175 |
2024 June | 141 | 35 | 176 |
2024 May | 114 | 51 | 165 |
2024 April | 100 | 27 | 127 |
2024 March | 113 | 30 | 143 |
2024 February | 99 | 37 | 136 |
2024 January | 105 | 41 | 146 |
2023 December | 98 | 27 | 125 |
2023 November | 103 | 37 | 140 |
2023 October | 79 | 37 | 116 |
2023 September | 106 | 29 | 135 |
2023 August | 86 | 22 | 108 |
2023 July | 83 | 45 | 128 |
2023 June | 69 | 29 | 98 |
2023 May | 83 | 26 | 109 |
2023 April | 77 | 49 | 126 |
2023 March | 91 | 45 | 136 |
2023 February | 72 | 26 | 98 |
2023 January | 64 | 35 | 99 |
2022 December | 78 | 61 | 139 |
2022 November | 51 | 24 | 75 |
2022 October | 46 | 36 | 82 |
2022 September | 32 | 42 | 74 |
2022 August | 41 | 57 | 98 |
2022 July | 37 | 40 | 77 |
2022 June | 47 | 37 | 84 |
2022 May | 87 | 52 | 139 |
2022 April | 96 | 44 | 140 |
2022 March | 91 | 68 | 159 |
2022 February | 55 | 55 | 110 |
2022 January | 87 | 60 | 147 |
2021 December | 55 | 73 | 128 |
2021 November | 88 | 71 | 159 |
2021 October | 91 | 70 | 161 |
2021 September | 81 | 64 | 145 |
2021 August | 83 | 54 | 137 |
2021 July | 43 | 38 | 81 |
2021 June | 52 | 59 | 111 |
2021 May | 62 | 45 | 107 |
2021 April | 77 | 99 | 176 |
2021 March | 76 | 43 | 119 |
2021 February | 93 | 43 | 136 |
2021 January | 90 | 43 | 133 |
2020 December | 69 | 35 | 104 |
2020 November | 58 | 28 | 86 |
2020 October | 57 | 28 | 85 |
2020 September | 46 | 16 | 62 |
2020 August | 46 | 28 | 74 |
2020 July | 59 | 14 | 73 |
2020 June | 39 | 30 | 69 |
2020 May | 35 | 27 | 62 |
2020 April | 42 | 34 | 76 |
2020 March | 25 | 30 | 55 |
2020 February | 16 | 9 | 25 |
2020 January | 4 | 11 | 15 |
2019 December | 8 | 10 | 18 |
2019 November | 2 | 9 | 11 |
2019 October | 0 | 13 | 13 |
2019 September | 11 | 14 | 25 |
2019 August | 5 | 5 | 10 |
2019 July | 5 | 28 | 33 |
2019 June | 4 | 48 | 52 |
2019 May | 8 | 143 | 151 |
2019 April | 11 | 53 | 64 |
2019 March | 1 | 24 | 25 |
2019 February | 7 | 18 | 25 |
2019 January | 4 | 14 | 18 |
2018 December | 5 | 7 | 12 |
2018 November | 6 | 8 | 14 |
2018 October | 2 | 6 | 8 |
2018 September | 10 | 5 | 15 |
2018 August | 0 | 14 | 14 |
2018 July | 0 | 11 | 11 |
2018 June | 0 | 11 | 11 |
2018 May | 0 | 4 | 4 |
2018 April | 0 | 7 | 7 |
2018 March | 18 | 16 | 34 |
2018 February | 82 | 20 | 102 |
2018 January | 97 | 23 | 120 |
2017 December | 108 | 17 | 125 |
2017 November | 79 | 21 | 100 |
2017 October | 107 | 19 | 126 |
2017 September | 78 | 40 | 118 |
2017 August | 78 | 26 | 104 |
2017 July | 103 | 22 | 125 |
2017 June | 93 | 28 | 121 |
2017 May | 74 | 31 | 105 |
2017 April | 80 | 23 | 103 |
2017 March | 71 | 25 | 96 |
2017 February | 66 | 16 | 82 |
2017 January | 81 | 15 | 96 |
2016 December | 175 | 37 | 212 |
2016 November | 175 | 22 | 197 |
2016 October | 188 | 17 | 205 |
2016 September | 259 | 30 | 289 |
2016 August | 207 | 21 | 228 |
2016 July | 70 | 17 | 87 |
2016 June | 7 | 24 | 31 |
2016 May | 5 | 18 | 23 |
2016 April | 4 | 3 | 7 |
2016 March | 7 | 6 | 13 |
2016 February | 8 | 14 | 22 |
2016 January | 8 | 20 | 28 |
2015 December | 11 | 1 | 12 |
2015 November | 10 | 1 | 11 |
2015 October | 11 | 1 | 12 |
2015 September | 2 | 14 | 16 |
2015 August | 9 | 4 | 13 |
2015 July | 273 | 24 | 297 |
2015 June | 252 | 14 | 266 |
2015 May | 236 | 31 | 267 |
2015 April | 216 | 18 | 234 |
2015 March | 241 | 21 | 262 |
2015 February | 163 | 8 | 171 |
2015 January | 140 | 14 | 154 |
2014 December | 141 | 7 | 148 |
2014 November | 132 | 6 | 138 |
2014 October | 125 | 8 | 133 |
2014 September | 84 | 4 | 88 |
2014 August | 101 | 5 | 106 |
2014 July | 98 | 8 | 106 |
2014 June | 109 | 9 | 118 |
2014 May | 100 | 8 | 108 |
2014 April | 113 | 7 | 120 |
2014 March | 111 | 21 | 132 |
2014 February | 95 | 16 | 111 |
2014 January | 69 | 11 | 80 |
2013 December | 64 | 12 | 76 |
2013 November | 21 | 13 | 34 |
2013 October | 8 | 9 | 17 |
2013 September | 6 | 19 | 25 |
2013 August | 7 | 39 | 46 |
2013 July | 11 | 19 | 30 |
2013 June | 3 | 33 | 36 |
2013 May | 11 | 29 | 40 |
2013 April | 7 | 43 | 50 |
2013 March | 8 | 19 | 27 |