Case report
Incontinentia Pigmenti: Three New Cases That Demonstrate it is not Only a Matter of Women
Incontinentia Pigmenti: Tres Nuevos Casos Que Demuestran Que no es Sólo Cosa de Mujeres
Read
7035
Timeswas read the article
3014
Total PDF
4021
Total HTML
Share statistics
array:24 [ "pii" => "S1578219007704079" "issn" => "15782190" "doi" => "10.1016/S1578-2190(07)70407-9" "estado" => "S300" "fechaPublicacion" => "2007-03-01" "aid" => "70407" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "copyrightAnyo" => "2007" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2007;98:112-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2860 "formatos" => array:3 [ "EPUB" => 40 "HTML" => 1842 "PDF" => 978 ] ] "Traduccion" => array:1 [ "es" => array:15 [ "pii" => "13100618" "issn" => "00017310" "estado" => "S300" "fechaPublicacion" => "2007-03-01" "documento" => "article" "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2007;98:112-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 15740 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 13211 "PDF" => 2527 ] ] "es" => array:12 [ "idiomaDefecto" => true "titulo" => "<span class="elsevierStyleItalic">Incontinentia pigmenti</span>: tres nuevos casos que demuestran que no es sólo cosa de mujeres" "tienePdf" => array:2 [ 0 => "es" 1 => "en" ] "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "112" "paginaFinal" => "115" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "<span class="elsevierStyleItalic">Incontinentia pigmenti</span>: three new cases that demonstrate it is not only a matter of women" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:2 [ "es" => true "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig1" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "copyright" => "Elsevier España" "figura" => array:1 [ 0 => array:4 [ "imagen" => "103v98n02-13100618fig01.jpg" "Alto" => 724 "Ancho" => 969 "Tamanyo" => 44467 ] ] "descripcion" => array:1 [ "es" => "Eritema y vesiculación sobre base inflamatoria con distribución lineal longitudinal en extremidades inferiores (estadio 1). Placa verrucosa hiperqueratósica en rodilla (estadio 2)." ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M Feito-Rodríguez, J García-Macarrón, E Ruiz Bravo-Burguillos, Á Vera-Casaño, R de Lucas-Laguna" "autores" => array:5 [ 0 => array:2 [ "Iniciales" => "M" "apellidos" => "Feito-Rodríguez" ] 1 => array:2 [ "Iniciales" => "J" "apellidos" => "García-Macarrón" ] 2 => array:2 [ "Iniciales" => "E" "apellidos" => "Ruiz Bravo-Burguillos" ] 3 => array:2 [ "nombre" => "Á" "apellidos" => "Vera-Casaño" ] 4 => array:2 [ "Iniciales" => "R" "apellidos" => "de Lucas-Laguna" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219007704079" "doi" => "10.1016/S1578-2190(07)70407-9" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007704079?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13100618?idApp=UINPBA000044" "url" => "/00017310/0000009800000002/v0_201507151217/13100618/v0_201507151219/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219007704080" "issn" => "15782190" "doi" => "10.1016/S1578-2190(07)70408-0" "estado" => "S300" "fechaPublicacion" => "2007-03-01" "aid" => "70408" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2007;98:116-20" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3175 "formatos" => array:3 [ "EPUB" => 45 "HTML" => 1735 "PDF" => 1395 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>" "titulo" => "Pachydermoperiostosis (Touraine-Solente-Golé syndrome). Case report" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "116" "paginaFinal" => "120" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Paquidermoperiostosis (Síndrome de Touraine-Solente-Golé). Descripción de un Caso" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.C. Santos-Durán, M. Yuste-Chaves, O. Martínez-González, M.T. Alonso-San Pablo, J. Sánchez-Estella" "autores" => array:5 [ 0 => array:2 [ "nombre" => "J.C." "apellidos" => "Santos-Durán" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Yuste-Chaves" ] 2 => array:2 [ "nombre" => "O." "apellidos" => "Martínez-González" ] 3 => array:2 [ "nombre" => "M.T." "apellidos" => "Alonso-San Pablo" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Sánchez-Estella" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:8 [ "pii" => "13100622" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13100622?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007704080?idApp=UINPBA000044" "url" => "/15782190/0000009800000002/v1_201304241405/S1578219007704080/v1_201304241405/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219007704067" "issn" => "15782190" "doi" => "10.1016/S1578-2190(07)70406-7" "estado" => "S300" "fechaPublicacion" => "2007-03-01" "aid" => "70406" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2007;98:109-11" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3387 "formatos" => array:3 [ "EPUB" => 42 "HTML" => 2246 "PDF" => 1099 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>" "titulo" => "Familial Presentation of Multiple Scalp Tumors" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "109" "paginaFinal" => "111" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tumoraciones Mùltiples en Cuero Cabelludo de Presentaciòn Familiar" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Novo-Torres, C. Laredo-Ortiz, E. Castellar-Nájera, E. Lorda-Barraguer, C. Alenda-González" "autores" => array:5 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Novo-Torres" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Laredo-Ortiz" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Castellar-Nájera" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Lorda-Barraguer" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Alenda-González" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:8 [ "pii" => "13100617" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13100617?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007704067?idApp=UINPBA000044" "url" => "/15782190/0000009800000002/v1_201304241405/S1578219007704067/v1_201304241405/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>" "titulo" => "Incontinentia Pigmenti: Three New Cases That Demonstrate it is not Only a Matter of Women" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "112" "paginaFinal" => "115" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "M. Feito-Rodríguez, J. García-Macarrón, E. Ruiz Bravo-Burguillos, Á. Vera-Casaño, R. de Lucas-Laguna" "autores" => array:5 [ 0 => array:4 [ "nombre" => "M." "apellidos" => "Feito-Rodríguez" "email" => array:1 [ 0 => "marta8marta@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "García-Macarrón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "E." "apellidos" => "Ruiz Bravo-Burguillos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "Á." "apellidos" => "Vera-Casaño" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 4 => array:3 [ "nombre" => "R." "apellidos" => "de Lucas-Laguna" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Carlos Haya, Málaga, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Dermatología. Hospital Universitario La Paz. Paseo de la Castellana, 261. 28046 Madrid. Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "<span class="elsevierStyleItalic">Incontinentia Pigmenti</span>: Tres Nuevos Casos Que Demuestran Que no es Sólo Cosa de Mujeres" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2006-09-15" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec83866" "palabras" => array:2 [ 0 => "<span class="elsevierStyleItalic">incontinentia pigmenti</span>" 1 => "hereditary bullous disease" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec83865" "palabras" => array:2 [ 0 => "<span class="elsevierStyleItalic">incontinentia pigmenti</span>" 1 => "enfermedad ampollosa hereditaria" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleItalic">Incontinentia pigmenti</span> is a rare, dominantly X-linked genodermatosis characterized by multisystemic involvement that is lethal prenatally in the majority of affected males and shows great clinical variability when it is expressed in women. Recently it has been shown that mutations of the gene NEMO/IKK-g located in Xq28 cause the expression of the disease, being only one mutation responsible for approximately 80% of the cases. The diagnosis of <span class="elsevierStyleItalic">incontinentia pigmenti</span> is performed based on clinical features and family history with the support of histological findings. Nevertheless, as the gene responsible for the phenotype of the disease has been identified, a genetic study may be employed for doubtful cases. We report three cases of this entity (two women and one man) in different clinical stages of development that show the broad clinical spectrum we may encounter in the clinic.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La <span class="elsevierStyleItalic">incontinentia pigmenti</span> es una genodermatosis infrecuente con carácter multisistémico que sigue un patrón de herencia dominante ligado a X, por lo que resulta letal en la mayoría de varones afectados intraútero y muestra gran variabilidad clínica cuando se expresa en mujeres. Recientemente se ha encontrado que las mutaciones del gen NEMO/IKK-γ localizado en Xq28 causan la expresión de la enfermedad, siendo una única mutación la responsable de aproximadamente un 80% de los casos. La <span class="elsevierStyleItalic">incontinentia pigmenti</span> interesa a varias especialidades médicas, aunque son la clínica cutánea y la historia familiar las que marcan el diagnóstico, ayudadas de los hallazgos histológicos. No obstante, la identificación reciente del gen responsable del fenotipo de la enfermedad permite la resolución de muchos casos dudosos mediante estudio genético.</p><p class="elsevierStyleSimplePara elsevierViewall">Presentamos a continuación tres nuevos casos de esta patología (dos mujeres y un varón) en diferentes estadios evolutivos, que muestran el amplio espectro clínico con el que esta patología puede llegar a nuestra consulta.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti: A review and update on the molecular basis of pathophysiology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.L. Berlin" 1 => "A.S. Paller" 2 => "L.S. Chan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2002" "volumen" => "47" "paginaInicial" => "169" "paginaFinal" => "187" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12140463" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical study of 40 cases of incontinentia pigmenti" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Hadj-Rabia" 1 => "D. Froidevaux" 2 => "N. Bodak" 3 => "D. Hamel-Teillac" 4 => "A. Smahi" 5 => "Y. Touil" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archderm.139.9.1163" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2003" "volumen" => "139" "paginaInicial" => "1163" "paginaFinal" => "1170" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12975158" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti case series: clinical spectrum of incontinentia pigmenti in 53 female patients and their relatives" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.A. Phan" 1 => "O. Wargon" 2 => "A.M. Turner" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2230.2005.01848.x" "Revista" => array:6 [ "tituloSerie" => "Clin Exp Dermatol" "fecha" => "2005" "volumen" => "30" "paginaInicial" => "474" "paginaFinal" => "480" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16045670" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Survival of male patients with Incontinentia Pigmenti carrying a lethal mutation can be explained by somatic mosaicism or Klinefelter Syndrome" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "The International Incontinentia Pigmenti (IP) Consortium" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Hum Genet" "fecha" => "2001" "volumen" => "69" "paginaInicial" => "1210" "paginaFinal" => "1217" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11673821" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genomic rearrangement in NEMO impairs NF-kB activation and is a cause of incontinentia pigmenti" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "The International Incontinentia Pigmenti (IP) Consortium" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/35013114" "Revista" => array:6 [ "tituloSerie" => "Nature" "fecha" => "2000" "volumen" => "405" "paginaInicial" => "466" "paginaFinal" => "472" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10839543" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti in a surviving male is accompanied by hypohidrotic ectodermal dysplasia and recurrent infection" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Mansour" 1 => "H. Woffendin" 2 => "S. Mitton" 3 => "I. Jeffery" 4 => "T. Jakins" 5 => "S. Kenwrick" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med Genet" "fecha" => "2001" "volumen" => "99" "paginaInicial" => "172" "paginaFinal" => "177" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11241484" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Male cases of incontinentia pigmenti: case report and review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.E. Scheuerle" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med Genet" "fecha" => "1998" "volumen" => "77" "paginaInicial" => "201" "paginaFinal" => "218" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9605587" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti: a world statistical analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.G. Carney" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1976" "volumen" => "112" "paginaInicial" => "535" "paginaFinal" => "542" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1267462" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti (Bloch-Sulzberger syndrome)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.J. Landy" 1 => "D. Donnai" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Med Genet" "fecha" => "1993" "volumen" => "30" "paginaInicial" => "53" "paginaFinal" => "59" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8423608" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A retrospective study of incontinentia pigmenti seen at the National Skin Centre, Singapore over a 10-year period" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Y.C. Chan" 1 => "Y.C. Gima" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Acad Med Singapore" "fecha" => "2001" "volumen" => "30" "paginaInicial" => "409" "paginaFinal" => "413" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11503550" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti. A fourgeneration study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.A. Wiklund" 1 => "W.L. Weston" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1980" "volumen" => "116" "paginaInicial" => "701" "paginaFinal" => "703" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7377807" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti (Bloch-Sulzberger syndrome): seven case reports from one family" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. Spallone" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Ophthalmol" "fecha" => "1987" "volumen" => "71" "paginaInicial" => "629" "paginaFinal" => "634" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3115288" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incontinentia pigmenti. A longitudinal study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.E. O’Brien" 1 => "M. Feingold" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Dis Child" "fecha" => "1985" "volumen" => "139" "paginaInicial" => "711" "paginaFinal" => "712" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2409793" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ocular manifestations of incontinentia pigmenti" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G. Holmström" 1 => "K. Thorén" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Acta Ophtalmol Scand" "fecha" => "2000" "volumen" => "78" "paginaInicial" => "348" "paginaFinal" => "353" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Disorders of pigmentation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D. Weedon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Skin Pathology" "fecha" => "2002" "editorial" => "Churchill Livingstone" "editorialLocalizacion" => "Edinburgh" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000009800000002/v1_201304241405/S1578219007704079/v1_201304241405/en/main.assets" "Apartado" => array:4 [ "identificador" => "6183" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case Reports" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009800000002/v1_201304241405/S1578219007704079/v1_201304241405/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219007704079?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 October | 36 | 29 | 65 |
| 2024 September | 47 | 41 | 88 |
| 2024 August | 96 | 87 | 183 |
| 2024 July | 61 | 84 | 145 |
| 2024 June | 64 | 67 | 131 |
| 2024 May | 62 | 76 | 138 |
| 2024 April | 51 | 37 | 88 |
| 2024 March | 52 | 47 | 99 |
| 2024 February | 44 | 41 | 85 |
| 2024 January | 45 | 43 | 88 |
| 2023 December | 51 | 72 | 123 |
| 2023 November | 45 | 40 | 85 |
| 2023 October | 52 | 32 | 84 |
| 2023 September | 45 | 38 | 83 |
| 2023 August | 22 | 33 | 55 |
| 2023 July | 36 | 49 | 85 |
| 2023 June | 44 | 36 | 80 |
| 2023 May | 32 | 27 | 59 |
| 2023 April | 29 | 20 | 49 |
| 2023 March | 23 | 24 | 47 |
| 2023 February | 23 | 32 | 55 |
| 2023 January | 27 | 31 | 58 |
| 2022 December | 26 | 34 | 60 |
| 2022 November | 15 | 25 | 40 |
| 2022 October | 17 | 36 | 53 |
| 2022 September | 21 | 60 | 81 |
| 2022 August | 65 | 41 | 106 |
| 2022 July | 48 | 38 | 86 |
| 2022 June | 23 | 29 | 52 |
| 2022 May | 52 | 45 | 97 |
| 2022 April | 35 | 44 | 79 |
| 2022 March | 36 | 65 | 101 |
| 2022 February | 32 | 32 | 64 |
| 2022 January | 28 | 28 | 56 |
| 2021 December | 33 | 44 | 77 |
| 2021 November | 36 | 44 | 80 |
| 2021 October | 28 | 46 | 74 |
| 2021 September | 29 | 47 | 76 |
| 2021 August | 25 | 21 | 46 |
| 2021 July | 23 | 28 | 51 |
| 2021 June | 31 | 37 | 68 |
| 2021 May | 30 | 32 | 62 |
| 2021 April | 65 | 64 | 129 |
| 2021 March | 62 | 15 | 77 |
| 2021 February | 49 | 19 | 68 |
| 2021 January | 52 | 19 | 71 |
| 2020 December | 43 | 15 | 58 |
| 2020 November | 34 | 19 | 53 |
| 2020 October | 26 | 6 | 32 |
| 2020 September | 23 | 13 | 36 |
| 2020 August | 34 | 21 | 55 |
| 2020 July | 13 | 9 | 22 |
| 2020 June | 44 | 17 | 61 |
| 2020 May | 41 | 18 | 59 |
| 2020 April | 37 | 21 | 58 |
| 2020 March | 30 | 16 | 46 |
| 2020 February | 6 | 3 | 9 |
| 2020 January | 0 | 6 | 6 |
| 2019 November | 0 | 5 | 5 |
| 2019 October | 0 | 1 | 1 |
| 2019 September | 0 | 6 | 6 |
| 2019 August | 0 | 1 | 1 |
| 2019 July | 0 | 14 | 14 |
| 2019 June | 0 | 8 | 8 |
| 2019 May | 1 | 48 | 49 |
| 2019 April | 0 | 11 | 11 |
| 2019 March | 0 | 3 | 3 |
| 2019 February | 0 | 4 | 4 |
| 2019 January | 0 | 0 | 0 |
| 2018 February | 11 | 4 | 15 |
| 2018 January | 26 | 11 | 37 |
| 2017 December | 29 | 11 | 40 |
| 2017 November | 18 | 6 | 24 |
| 2017 October | 22 | 4 | 26 |
| 2017 September | 32 | 5 | 37 |
| 2017 August | 44 | 8 | 52 |
| 2017 July | 29 | 9 | 38 |
| 2017 June | 43 | 39 | 82 |
| 2017 May | 25 | 28 | 53 |
| 2017 April | 23 | 15 | 38 |
| 2017 March | 14 | 31 | 45 |
| 2017 February | 15 | 20 | 35 |
| 2017 January | 17 | 13 | 30 |
| 2016 December | 49 | 11 | 60 |
| 2016 November | 50 | 9 | 59 |
| 2016 October | 56 | 13 | 69 |
| 2016 September | 62 | 15 | 77 |
| 2016 August | 71 | 20 | 91 |
| 2016 July | 50 | 12 | 62 |
| 2016 June | 8 | 3 | 11 |
| 2016 May | 10 | 10 | 20 |
| 2016 April | 6 | 9 | 15 |
| 2016 March | 6 | 5 | 11 |
| 2016 February | 9 | 2 | 11 |
| 2016 January | 4 | 0 | 4 |
| 2015 December | 13 | 3 | 16 |
| 2015 November | 13 | 1 | 14 |
| 2015 October | 5 | 1 | 6 |
| 2015 September | 6 | 1 | 7 |
| 2015 August | 11 | 3 | 14 |
| 2015 July | 14 | 8 | 22 |
| 2015 June | 23 | 3 | 26 |
| 2015 May | 68 | 15 | 83 |
| 2015 April | 22 | 8 | 30 |
| 2015 March | 29 | 7 | 36 |
| 2015 February | 18 | 8 | 26 |
| 2015 January | 18 | 6 | 24 |
| 2014 December | 18 | 18 | 36 |
| 2014 November | 17 | 14 | 31 |
| 2014 October | 28 | 12 | 40 |
| 2014 September | 29 | 9 | 38 |
| 2014 August | 26 | 15 | 41 |
| 2014 July | 42 | 15 | 57 |
| 2014 June | 49 | 13 | 62 |
| 2014 May | 52 | 10 | 62 |
| 2014 April | 46 | 13 | 59 |
| 2014 March | 60 | 19 | 79 |
| 2014 February | 36 | 16 | 52 |
| 2014 January | 46 | 17 | 63 |
| 2013 December | 50 | 24 | 74 |
| 2013 November | 34 | 14 | 48 |
| 2013 October | 41 | 24 | 65 |
| 2013 September | 41 | 19 | 60 |
| 2013 August | 27 | 51 | 78 |
| 2013 July | 39 | 43 | 82 |
| 2013 June | 29 | 39 | 68 |
| 2013 May | 24 | 40 | 64 |
| 2013 April | 30 | 26 | 56 |
| 2013 March | 57 | 21 | 78 |
| 2013 February | 37 | 12 | 49 |
| 2013 January | 14 | 9 | 23 |
Show all
