Statistics

 array:22 [
  "pii" => "S0001731024007166"
  "issn" => "00017310"
  "doi" => "10.1016/j.ad.2024.07.018"
  "estado" => "S200"
  "fechaPublicacion" => "2024-10-15"
  "aid" => "4071"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2024"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "itemSiguiente" => array:17 [
    "pii" => "S0001731024007609"
    "issn" => "00017310"
    "doi" => "10.1016/j.ad.2024.10.003"
    "estado" => "S100"
    "fechaPublicacion" => "2024-10-18"
    "aid" => "4079"
    "copyright" => "AEDV"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "crp"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:9 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Carta cient&#237;fico-cl&#237;nica</span>"
      "titulo" => " Oral Ruxolitinib could Increase the Aggressiveness of Cutaneous Squamous Cell Carcinomas&#58; A 6-Patient Series"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Ruxolitinib oral puede aumentar la agresividad de los carcinomas escamosos cut&#225;neos&#58; serie de 6 pacientes"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46;A&#46; Lasheras-P&#233;rez, L&#46; Puebla-Tornero, J&#46; Ca&#241;ueto, B&#46; de Unamuno-Bustos, R&#46; Botella-Estrada"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "M&#46;A&#46;"
              "apellidos" => "Lasheras-P&#233;rez"
            ]
            1 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Puebla-Tornero"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Ca&#241;ueto"
            ]
            3 => array:2 [
              "nombre" => "B&#46;"
              "apellidos" => "de Unamuno-Bustos"
            ]
            4 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Botella-Estrada"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731024007609?idApp=UINPBA000044"
    "url" => "/00017310/unassign/S0001731024007609/v1_202410180433/en/main.assets"
  ]
  "itemAnterior" => array:17 [
    "pii" => "S0001731023004908"
    "issn" => "00017310"
    "doi" => "10.1016/j.ad.2023.05.022"
    "estado" => "S200"
    "fechaPublicacion" => "2023-07-18"
    "aid" => "3547"
    "copyright" => "AEDV"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "crp"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letter</span>"
      "titulo" => "Recalcitrant Hailey&#8211;Hailey Disease With Satisfactory Response to Apremilast"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Enfermedad de Hailey-Hailey recalcitrante con respuesta satisfactoria a apremilast"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 2049
              "Ancho" => 1555
              "Tamanyo" => 362161
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Red-brown plaques with superficial erosions and a macerated appearance&#44; located in the axillary folds &#40;A&#41; and groin &#40;B&#41; before the start of treatment with apremilast&#46; Note the improvement of the lesions after 6 months of treatment with apremilast 30<span class="elsevierStyleHsp" style=""></span>mg twice a day &#40;C and D&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46; Mansilla-Polo, C&#46; Abril-P&#233;rez, M&#46;&#193;&#46; Navarro-Mira, R&#46; Botella-Estrada"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Mansilla-Polo"
            ]
            1 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Abril-P&#233;rez"
            ]
            2 => array:2 [
              "nombre" => "M&#46;&#193;&#46;"
              "apellidos" => "Navarro-Mira"
            ]
            3 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Botella-Estrada"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731023004908?idApp=UINPBA000044"
    "url" => "/00017310/unassign/S0001731023004908/v1_202307180913/en/main.assets"
  ]
  "es" => array:18 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">DERMATOLOG&#205;A PR&#193;CTICA</span>"
    "titulo" => "Luz de Wood en dermatosis inflamatorias&#44; autoinmunes&#44; infecciones y c&#225;ncer cut&#225;neo"
    "tieneTextoCompleto" => true
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "S&#46; Gomez-Martinez, J&#46; Ibaceta Ayala, D&#46; Morgado-Carrasco"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "S&#46;"
            "apellidos" => "Gomez-Martinez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Ibaceta Ayala"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:4 [
            "nombre" => "D&#46;"
            "apellidos" => "Morgado-Carrasco"
            "email" => array:1 [
              0 => "morgadodaniel8@gmail.com"
            ]
            "referencia" => array:3 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
              2 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nic de Barcelona&#44; Universitat de Barcelona&#44; Barcelona&#44; Espa&#241;a"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Integram&#233;dica&#44; Redsalud&#44; Santiago&#44; Chile"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital de Figueres&#44; Fundaci&#243; Salut Empord&#224;&#44; Figures&#44; Girona&#44; Espa&#241;a"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Autor para correspondencia&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Wood&#39;s Light in Inflammatory And Autoimmune Dermatoses&#44; Infections and Skin Cancer"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0035"
        "etiqueta" => "Figura 7"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr7.jpeg"
            "Alto" => 2108
            "Ancho" => 2470
            "Tamanyo" => 704265
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">A&#41; Carcinoma basocelular mal delimitado en la zona paranasal izquierda&#46; B&#41; Delimitaci&#243;n prequir&#250;rgica con luz de Wood&#46; C&#41; Cicatriz de melanoma en el antebrazo derecho&#44; previa ampliaci&#243;n de m&#225;rgenes&#46; Dif&#237;cil de detectar cl&#237;nicamente&#46; D&#41; La luz de Wood permite encontrar f&#225;cilmente la cicatriz &#40;flechas negras&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introducci&#243;n</span><p id="par0005" class="elsevierStylePara elsevierViewall">La luz de Wood &#40;LW&#41; es un m&#233;todo diagn&#243;stico r&#225;pido&#44; econ&#243;mico&#44; accesible y no invasivo&#44; basado en el uso de una fuente de radiaci&#243;n ultravioleta &#40;UV&#41; con una longitud de onda de aproximadamente 365<span class="elsevierStyleHsp" style=""></span>nm&#46; Desde su invenci&#243;n en 1903 por el f&#237;sico Robert Wood&#44; ha facilitado el diagn&#243;stico de m&#250;ltiples enfermedades cut&#225;neas<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">1</span></a>&#46; Cl&#225;sicamente ha sido empleada en infecciones f&#250;ngicas superficiales y en alteraciones pigmentarias&#46; En los &#250;ltimos a&#241;os&#44; pareciera que la utilizaci&#243;n de la LW ha disminuido entre los dermat&#243;logos<a class="elsevierStyleCrossRef" href="#bib0395"><span class="elsevierStyleSup">2</span></a>&#46; En este art&#237;culo revisaremos la utilidad de la luz de Wood en dermatosis inflamatorias como infecciosas y en el manejo del c&#225;ncer cut&#225;neo&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Aspectos t&#233;cnicos y dispositivos</span><p id="par0010" class="elsevierStylePara elsevierViewall">Originalmente&#44; la LW consist&#237;a en una l&#225;mpara de mercurio con un filtro de silicato de bario con &#243;xido de n&#237;quel&#44; que permit&#237;a el paso de radiaci&#243;n UV de longitud de onda de 320 a 400 nan&#243;metros &#40;nm&#41;&#44; con un pico en 365<span class="elsevierStyleHsp" style=""></span>nm<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">1</span></a>&#46; Las l&#225;mparas de Wood cl&#225;sicas asocian una lupa de aumento de 1&#44;5&#215;&#46; Sin embargo&#44; pueden ser aparatosas y de alto coste y esto puede dificultar su utilizaci&#243;n<a class="elsevierStyleCrossRef" href="#bib0400"><span class="elsevierStyleSup">3</span></a>&#46; Actualmente est&#225;n disponibles linternas LED de luz negra&#44; livianas y de peque&#241;o tama&#241;o&#44; con picos de emisi&#243;n de 365 a 395<span class="elsevierStyleHsp" style=""></span>nm y precios alrededor de 15 a 30 euros&#46; Se han demostrado igualmente efectivas para detectar la fluorescencia&#44; aunque carecen de lupa de magnificaci&#243;n<a class="elsevierStyleCrossRefs" href="#bib0405"><span class="elsevierStyleSup">4-6</span></a>&#46; Recientemente&#44; se ha incorporado luz ultravioleta de 365<span class="elsevierStyleHsp" style=""></span>nm de longitud de onda &#40;UV365&#41; a algunos dermatoscopios&#44; lo que ha permitido describir con m&#225;s detalle los patrones de fluorescencia de diversas enfermedades cut&#225;neas<a class="elsevierStyleCrossRef" href="#bib0420"><span class="elsevierStyleSup">7</span></a>&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">La capacidad diagn&#243;stica de la LW se basa en el fen&#243;meno de fluorescencia&#46; Los fotones de la UV365 excitan electrones de mol&#233;culas llamadas fluor&#243;foros que&#44; al volver al estado energ&#233;tico basal&#44; liberan fotones en el rango de la luz visible<a class="elsevierStyleCrossRef" href="#bib0425"><span class="elsevierStyleSup">8</span></a>&#46; En las longitudes de onda de la LW&#44; la fluorescencia end&#243;gena de la piel se origina principalmente en la dermis&#44; donde los enlaces cruzados de pepsina y colagenasa del col&#225;geno estructural emiten una fluorescencia azulada<a class="elsevierStyleCrossRefs" href="#bib0425"><span class="elsevierStyleSup">8&#44;9</span></a>&#46; Sin embargo&#44; la melanina absorbe eficientemente esta longitud de onda&#44; disminuyendo la intensidad de la fluorescencia&#46; Esto permite que la LW resalte las diferencias entre hipo o hiperpigmentaciones<a class="elsevierStyleCrossRefs" href="#bib0435"><span class="elsevierStyleSup">10&#44;11</span></a>&#46; La LW tambi&#233;n evidencia la acumulaci&#243;n fluor&#243;foros ex&#243;genos&#44; como sustancias producidas por infecciones f&#250;ngicas y bacterianas&#44; o end&#243;genos&#44; como en el caso de las porfirias &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Exploraci&#243;n f&#237;sica</span><p id="par0020" class="elsevierStylePara elsevierViewall">La LW debe utilizarse en una habitaci&#243;n a oscuras<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">1</span></a>&#46; Cl&#225;sicamente se recomendaba encender la l&#225;mpara 60 s antes de la exploraci&#243;n&#44; ya que las l&#225;mparas de mercurio no emiten el espectro de radiaci&#243;n completo hasta alcanzar una presi&#243;n suficientemente elevada<a class="elsevierStyleCrossRef" href="#bib0445"><span class="elsevierStyleSup">12</span></a>&#46; Con las l&#225;mparas LED este decalaje temporal no es necesario&#46; La fuente de luz debe sostenerse a 10-12<span class="elsevierStyleHsp" style=""></span>cm de distancia la piel<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">1</span></a>&#44; aunque con las l&#225;mparas LED de luz m&#225;s focalizada puede ser necesario alejarlas 30 o 40<span class="elsevierStyleHsp" style=""></span>cm&#46; En caso de sospecha de infecciones&#44; debe evitarse lavar la piel antes&#44; ya que se puede diluir los fluor&#243;foros y causar falsos negativos<a class="elsevierStyleCrossRef" href="#bib0390"><span class="elsevierStyleSup">1</span></a>&#46; Sin embargo&#44; en trastornos de la pigmentaci&#243;n o lesiones pigmentadas&#44; es preferible lavar la cara y eliminar cosm&#233;ticos y fotoprotectores&#44; ya que estos pueden distorsionar la imagen y dificultar la delimitaci&#243;n cl&#237;nica de lesiones<a class="elsevierStyleCrossRef" href="#bib0450"><span class="elsevierStyleSup">13</span></a>&#46; Entre las causas de falsos positivos destacan las escamas hiperquerat&#243;sicas y secreciones como saliva&#44; suero&#44; semen y leche<a class="elsevierStyleCrossRef" href="#bib0450"><span class="elsevierStyleSup">13</span></a>&#44; as&#237; tambi&#233;n elementos ex&#243;genos como rotuladores de colores&#44; detergentes de ropa&#44; pelusas&#44; zumo de lim&#243;n&#44; cosm&#233;ticos&#44; tintes y pomadas<a class="elsevierStyleCrossRef" href="#bib0450"><span class="elsevierStyleSup">13</span></a>&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Precauciones</span><p id="par0025" class="elsevierStylePara elsevierViewall">La exposici&#243;n cr&#243;nica a la radiaci&#243;n UVA&#44; presente en la LW&#44; est&#225; asociada al desarrollo de cataratas y envejecimiento ocular<a class="elsevierStyleCrossRefs" href="#bib0455"><span class="elsevierStyleSup">14&#44;15</span></a>&#46; Sin embargo&#44; los oftalm&#243;logos han indicado que la LW no tiene efectos oculares negativos<a class="elsevierStyleCrossRef" href="#bib0465"><span class="elsevierStyleSup">16</span></a>&#46; Se recomienda cubrir los ojos de los ni&#241;os&#44; ya que su cristalino carece del pigmento protector de los adultos que absorbe la radiaci&#243;n UVA&#44; de manera que esta puede alcanzar la retina<a class="elsevierStyleCrossRefs" href="#bib0455"><span class="elsevierStyleSup">14&#44;15&#44;17</span></a>&#46; Adem&#225;s&#44; los ni&#241;os tienden a mirar a la luz directamente&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Luz de Wood en dermatosis inflamatorias o autoinmunes</span><p id="par0030" class="elsevierStylePara elsevierViewall">En el examen de lesiones de poroqueratosis con LW&#44; se ha descrito el signo de &#171;collar de diamantes&#187;&#44; correspondiente a la fluorescencia blanca de la escama hiperquerat&#243;sica que rodea el centro azul-negruzco<a class="elsevierStyleCrossRefs" href="#bib0415"><span class="elsevierStyleSup">6&#44;18</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a> A-B&#41;&#46; Sin embargo&#44; esta fluorescencia es inconstante<a class="elsevierStyleCrossRef" href="#bib0415"><span class="elsevierStyleSup">6</span></a>&#46; En la poroqueratosis folicular&#44; se observa un patr&#243;n de fluorescencia blanca punteada en el interior&#44; correspondiente a la lamela de los fol&#237;culos dilatados<a class="elsevierStyleCrossRef" href="#bib0415"><span class="elsevierStyleSup">6</span></a>&#46; Bajo la LW las lesiones subcl&#237;nicas de morfea se observan como m&#225;culas oscuras bien delimitadas&#44; lo que puede facilitar el diagn&#243;stico precoz y el seguimiento de estos pacientes<a class="elsevierStyleCrossRef" href="#bib0480"><span class="elsevierStyleSup">19</span></a>&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Luz de Wood en trastornos pigmentarios</span><p id="par0035" class="elsevierStylePara elsevierViewall">El uso por excelencia de la LW es en los trastornos pigmentarios&#44; como en el caso del vit&#237;ligo<a class="elsevierStyleCrossRefs" href="#bib0465"><span class="elsevierStyleSup">16&#44;20&#44;21</span></a>&#46; La ausencia de melanina permite visualizar la fluorescencia azulada natural de la dermis con un borde muy bien delimitado<a class="elsevierStyleCrossRefs" href="#bib0435"><span class="elsevierStyleSup">10&#44;11</span></a>&#46; Bajo dermatoscopia con luz UV365 se ha descrito fluorescencia folicular homog&#233;nea en un 40&#37; de los casos de vit&#237;ligo<a class="elsevierStyleCrossRef" href="#bib0420"><span class="elsevierStyleSup">7</span></a>&#46; La LW puede detectar lesiones subcl&#237;nicas&#44; permitiendo un diagn&#243;stico precoz&#44; y evaluaci&#243;n de la respuesta al tratamiento<a class="elsevierStyleCrossRefs" href="#bib0490"><span class="elsevierStyleSup">21-23</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a> C-D&#41;&#46; En la esclerosis tuberosa&#44; la LW puede poner de manifiesto las m&#225;culas hipomel&#225;nicas&#44; especialmente la despigmentaci&#243;n en confeti&#44; menos aparente bajo luz visible que las cl&#225;sicas m&#225;culas lanceoladas<a class="elsevierStyleCrossRefs" href="#bib0505"><span class="elsevierStyleSup">24-26</span></a>&#46; En el melasma&#44; la LW puede ayudar a identificar la profundidad del dep&#243;sito de melanina y potencialmente predecir la respuesta a tratamientos<a class="elsevierStyleCrossRefs" href="#bib0520"><span class="elsevierStyleSup">27-29</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41;&#46; En el melasma epid&#233;rmico&#44; la hiperpigmentaci&#243;n se oscurece bajo la LW<a class="elsevierStyleCrossRefs" href="#bib0530"><span class="elsevierStyleSup">29-31</span></a>&#46; En cambio&#44; el melasma d&#233;rmico no muestra aumento del contraste<a class="elsevierStyleCrossRefs" href="#bib0530"><span class="elsevierStyleSup">29-31</span></a>&#46; Sin embargo&#44; la correlaci&#243;n histol&#243;gica de la clasificaci&#243;n del melasma por LW es controvertida&#58; hay estudios que sugieren una buena correlaci&#243;n&#44; mientras que otros indican que todos los melasmas tienen un componente d&#233;rmico<a class="elsevierStyleCrossRefs" href="#bib0520"><span class="elsevierStyleSup">27&#44;28&#44;32</span></a>&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0040" class="elsevierStylePara elsevierViewall">La hipomelanosis macular progresiva es un trastorno pigmentario causado por <span class="elsevierStyleItalic">Cutibacterium acnes</span>&#44; una bacteria grampositiva que habita en el fol&#237;culo piloso y produce coproporfirina III<a class="elsevierStyleCrossRefs" href="#bib0550"><span class="elsevierStyleSup">33-36</span></a>&#46; La LW acent&#250;a las zonas de hipopigmentaci&#243;n y muestra fluorescencia roja en los fol&#237;culos de las zonas hipopigmentadas<a class="elsevierStyleCrossRefs" href="#bib0550"><span class="elsevierStyleSup">33-35</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0015">fig&#46; 3</a> A-B&#41;&#46; La LW permite diferenciarla de la pitiriasis versicolor&#44; que presenta fluorescencia amarillenta &#40;<a class="elsevierStyleCrossRef" href="#fig0015">fig&#46; 3</a> C-D&#41;&#59; de la pitiriasis alba&#44; que debido a la paraqueratosis irregular no muestra fluorescencia&#44; o de la hipopigmentaci&#243;n postinflamatoria y la hipomelanosis gutatta idop&#225;tica&#44; que muestran la fluorescencia azulada de la dermis<a class="elsevierStyleCrossRefs" href="#bib0485"><span class="elsevierStyleSup">20&#44;35</span></a>&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Luz de Wood en infecciones cut&#225;neas</span><p id="par0045" class="elsevierStylePara elsevierViewall">El eritrasma&#44; producido por <span class="elsevierStyleItalic">Corynebacterium minutissimum</span>&#44; presenta fluorescencia rojo coral por la producci&#243;n de coproporfirina III<a class="elsevierStyleCrossRefs" href="#bib0570"><span class="elsevierStyleSup">37&#44;38</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0020">fig&#46; 4</a>&#41;&#46; Esto permite diferenciarlo de otras causas de intertrigo que no muestran fluorescencia como el intertrigo irritativo&#44; la candidiasis o la psoriasis inversa<a class="elsevierStyleCrossRefs" href="#bib0570"><span class="elsevierStyleSup">37&#44;38</span></a>&#46; En el caso de la <span class="elsevierStyleItalic">tinea cruris&#44;</span> hasta un 25&#37; pueden presentar fluorescencia azul-verdosa&#44; si est&#225;n causadas por <span class="elsevierStyleItalic">Microsporum</span>&#44; que produce el fluor&#243;foro pteridina<a class="elsevierStyleCrossRefs" href="#bib0420"><span class="elsevierStyleSup">7&#44;16</span></a>&#46; La tricobacteriosis&#44; causada por <span class="elsevierStyleItalic">Corynebacterium flavescens</span>&#44; presenta una fluorescencia blanca-amarillenta adherida al pelo axilar<a class="elsevierStyleCrossRefs" href="#bib0570"><span class="elsevierStyleSup">37&#44;39&#44;40</span></a> y se desconoce el fluor&#243;foro que la origina<a class="elsevierStyleCrossRefs" href="#bib0465"><span class="elsevierStyleSup">16&#44;41</span></a>&#46; La pitiriasis versicolor muestra una fluorescencia amarillo-verdosa&#44; originada por la porfirina pitirialactona producida por la <span class="elsevierStyleItalic">Malassezia globosa</span><a class="elsevierStyleCrossRefs" href="#bib0595"><span class="elsevierStyleSup">42-44</span></a>&#46; En las <span class="elsevierStyleItalic">tinea capitis</span> por <span class="elsevierStyleItalic">Microsporum canis</span> se observa una fluorescencia azul por el fluor&#243;foro pteridina<a class="elsevierStyleCrossRefs" href="#bib0610"><span class="elsevierStyleSup">45-48</span></a>&#46; Las infecciones por <span class="elsevierStyleItalic">Tricophyton</span> generalmente no presentan fluorescencia&#44; &#250;nicamente <span class="elsevierStyleItalic">Tricophyton</span><span class="elsevierStyleItalic">schoenleinii&#44;</span> causante de la ti&#241;a f&#225;vica&#44; muestra una fluorescencia azul p&#225;lida<a class="elsevierStyleCrossRefs" href="#bib0465"><span class="elsevierStyleSup">16&#44;20</span></a>&#46; Las infecciones por <span class="elsevierStyleItalic">Pseudomona aeruginosa</span> presentan fluorescencia verde&#44; debido la pioverdina&#44; pigmento quelante del hierro<a class="elsevierStyleCrossRefs" href="#bib0630"><span class="elsevierStyleSup">49-51</span></a>&#46; El uso de LW en heridas con sospecha de sobreinfecci&#243;n puede permitir el diagn&#243;stico precoz de sobreinfecci&#243;n por este pat&#243;geno&#44; as&#237; tambi&#233;n en las infecciones ungueales &#40;&#171;u&#241;a verde&#187;&#41;<a class="elsevierStyleCrossRefs" href="#bib0640"><span class="elsevierStyleSup">51&#44;52</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0025">fig&#46; 5</a>A&#41;&#46;</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><elsevierMultimedia ident="fig0025"></elsevierMultimedia></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Luz de Wood en parasitosis cut&#225;neas</span><p id="par0050" class="elsevierStylePara elsevierViewall">En la escabiosis&#44; la LW evidencia una fluorescencia blanca azulada en el surco acarino<a class="elsevierStyleCrossRefs" href="#bib0650"><span class="elsevierStyleSup">53&#44;54</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0025">fig&#46; 5</a> B-C&#41;&#46; Si se eval&#250;a el surco con un dermatoscopio con luz UV365&#44; se puede observar un punto de fluorescencia blanca o verde correspondiente al cuerpo del &#225;caro<a class="elsevierStyleCrossRefs" href="#bib0650"><span class="elsevierStyleSup">53&#44;54</span></a>&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Luz de Wood en c&#225;ncer cut&#225;neo y cirug&#237;a dermatol&#243;gica</span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Lentigo maligno</span><p id="par0055" class="elsevierStylePara elsevierViewall">La delimitaci&#243;n de los m&#225;rgenes tumorales en el lentigo maligno &#40;LM&#41; puede ser dif&#237;cil&#46; Pese a que las gu&#237;as recomiendan realizar m&#225;rgenes quir&#250;rgicos de entre 5 a 10<span class="elsevierStyleHsp" style=""></span>mm&#44; un estudio reciente &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>846&#41; mostr&#243; que se requer&#237;an m&#225;rgenes de 15<span class="elsevierStyleHsp" style=""></span>mm para alcanzar m&#225;rgenes libres en el 97&#37; de los casos &#40;solo un 62&#37; de los LM ten&#237;an m&#225;rgenes libres con resecciones con 5<span class="elsevierStyleHsp" style=""></span>mm de margen&#41;<a class="elsevierStyleCrossRef" href="#bib0660"><span class="elsevierStyleSup">55</span></a>&#46; En el LM&#44; el contraste generado por la LW entre la fluorescencia end&#243;gena de la piel sana y el oscurecimiento de las zonas con pigmento epid&#233;rmico puede ser &#250;til para delimitar el tumor<a class="elsevierStyleCrossRefs" href="#bib0665"><span class="elsevierStyleSup">56-59</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0030">fig&#46; 6</a> A-B&#41;&#44; y hay centros que utilizan LW sistem&#225;ticamente previo a realizar cirug&#237;a microgr&#225;fica de Mohs &#40;CMM&#41; en el LM<a class="elsevierStyleCrossRef" href="#bib0660"><span class="elsevierStyleSup">55</span></a>&#46; Se han descrito series de casos de LM en los que la LW permiti&#243; delimitar exitosamente el tumor&#44; resultando en m&#225;rgenes libres en el primer estadio de CMM&#44; adem&#225;s de permitir la detecci&#243;n precoz de recurrencias<a class="elsevierStyleCrossRefs" href="#bib0665"><span class="elsevierStyleSup">56&#44;58&#44;59</span></a>&#46; Hemos encontrado solo un estudio prospectivo comparando la delimitaci&#243;n de m&#225;rgenes quir&#250;rgicos de LM con LW versus el examen cl&#237;nico &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>60&#41; en CMM<a class="elsevierStyleCrossRef" href="#bib0670"><span class="elsevierStyleSup">57</span></a>&#46; El estudio sigui&#243; una estricta metodolog&#237;a&#58; dibujaron y midieron la delimitaci&#243;n prequir&#250;rgica con LW&#44; compar&#225;ndola con la delimitaci&#243;n cl&#237;nica&#46; Luego se realiz&#243; la extirpaci&#243;n a 5<span class="elsevierStyleHsp" style=""></span>mm por fuera de los m&#225;rgenes delimitados cl&#237;nicamente&#46; Finalmente&#44; se compar&#243; el dibujo de la delimitaci&#243;n prequir&#250;rgica con LW con el defecto quir&#250;rgico final &#40;tras obtener m&#225;rgenes libres con CMM&#41;&#46; Solo en 7 casos &#40;12&#37;&#41; la LW increment&#243; la delimitaci&#243;n de los m&#225;rgenes de resecci&#243;n comparada con el examen cl&#237;nico y solo en uno de ellos los m&#225;rgenes observados con la LW se correspond&#237;an histol&#243;gicamente con m&#225;rgenes afectados por el LM&#46; En este paciente&#44; la LW hubiera reducido el n&#250;mero de estadios necesarios de CMM&#46; En los 6 casos restantes&#44; la LW sobrestim&#243; los m&#225;rgenes tumorales&#46; Los autores concluyeron que la utilidad de la LW en CMM del LM era limitada&#44; ya que hubiera sobrestimado los m&#225;rgenes quir&#250;rgicos&#44; llevando a defectos finales de mayor tama&#241;o de manera innecesaria<a class="elsevierStyleCrossRef" href="#bib0670"><span class="elsevierStyleSup">57</span></a>&#46; Sin embargo&#44; la LW present&#243; un alto valor predictivo negativo &#40;87&#37;&#41;&#44; por lo que se puede deducir que&#44; si la LW no resalta zonas sospechosas fuera de la delimitaci&#243;n prequir&#250;rgica cl&#237;nica&#44; la probabilidad de que haya tumor es bastante baja y se podr&#237;an realizar m&#225;rgenes ajustados &#40;de 5<span class="elsevierStyleHsp" style=""></span>mm&#41;&#44; aunque esto debe ser evaluado en estudios prospectivos con un mayor n&#250;mero de pacientes&#46;</p><elsevierMultimedia ident="fig0030"></elsevierMultimedia></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Carcinoma basocelular</span><p id="par0060" class="elsevierStylePara elsevierViewall">En el carcinoma basocelular &#40;CBC&#41; y en el carcinoma escamoso cut&#225;neo &#40;CEC&#41;&#44; se puede utilizar LW por s&#237; sola &#40;<a class="elsevierStyleCrossRef" href="#fig0035">fig&#46; 7</a> A-B&#41; o tras aplicar &#225;cido 5-aminolevul&#237;nico &#40;5-ALA&#41;&#44; donde las c&#233;lulas tumorales emiten fluorescencia roja bajo LW debido a la acumulaci&#243;n del fluor&#243;foro protoporfirina IX<a class="elsevierStyleCrossRef" href="#bib0685"><span class="elsevierStyleSup">60</span></a>&#46; En un estudio prospectivo con 27 pacientes con CBC se utiliz&#243; fluorescencia por 5-ALA para delimitar el <span class="elsevierStyleItalic">debulking</span> en CMM<a class="elsevierStyleCrossRef" href="#bib0690"><span class="elsevierStyleSup">61</span></a>&#46; Se realizaron fotograf&#237;as de fluorescencia digital y se marc&#243; el margen de resecci&#243;n 1<span class="elsevierStyleHsp" style=""></span>mm alrededor de la fluorescencia&#46; En 15 pacientes el di&#225;metro de la lesi&#243;n por fluorescencia fue mayor que el di&#225;metro cl&#237;nico&#46; En el 44&#37; el margen delimitado por fluorescencia coincid&#237;a con el histopatol&#243;gico y la concordancia era m&#225;s frecuente en tumores &#8804; 1<span class="elsevierStyleHsp" style=""></span>cm que en<span class="elsevierStyleHsp" style=""></span>&#62; 1<span class="elsevierStyleHsp" style=""></span>cm&#46; Concluyeron que se podr&#237;a asegurar una ex&#233;resis completa con un margen de 2<span class="elsevierStyleHsp" style=""></span>mm del tumor delimitado por fluorescencia en lesiones<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>1<span class="elsevierStyleHsp" style=""></span>cm y en las que la fluorescencia coincide con la lesi&#243;n cl&#237;nica&#46; En tumores<span class="elsevierStyleHsp" style=""></span>&#62; 1<span class="elsevierStyleHsp" style=""></span>cm ser&#237;an necesarios m&#225;rgenes de 3<span class="elsevierStyleHsp" style=""></span>mm<a class="elsevierStyleCrossRef" href="#bib0690"><span class="elsevierStyleSup">61</span></a>&#46; Respecto a los CBC faciales&#44; en un estudio previo de dise&#241;o similar &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>26&#41; el diagn&#243;stico por fluorescencia mostr&#243; una sensibilidad del 38&#37; y una especificidad del 88&#37;&#46; Los autores concluyeron que no era &#250;til para delimitar lesiones en la zona H<a class="elsevierStyleCrossRef" href="#bib0695"><span class="elsevierStyleSup">62</span></a>&#46; Sin embargo&#44; en otro estudio prospectivo en CBC faciales &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>10&#41;&#44; el diagn&#243;stico con 5-ALA y LW con biopsias perif&#233;ricas preoperatorias de zonas de fluorescencia tenue&#44; consigui&#243; m&#225;rgenes libres en el 90&#37; de los pacientes<a class="elsevierStyleCrossRef" href="#bib0700"><span class="elsevierStyleSup">63</span></a>&#46; Dos estudios previos con CMM &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>22 y n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>12&#41; encontraron una buena correlaci&#243;n de la fluorescencia con la histolog&#237;a en alrededor del 50&#37; de los pacientes<a class="elsevierStyleCrossRefs" href="#bib0705"><span class="elsevierStyleSup">64&#44;65</span></a>&#46; Otros autores realizaron biopsias seriadas en zonas de fluorescencia y no fluorescencia &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>10&#41; y ex&#233;resis seg&#250;n fluorescencia &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>28&#41;&#44; encontrando una sensibilidad entre el 79 y el 94&#37;&#44; y una especificidad entre el 82 y el 100&#37;&#44; respectivamente<a class="elsevierStyleCrossRefs" href="#bib0715"><span class="elsevierStyleSup">66&#44;67</span></a>&#46;</p><elsevierMultimedia ident="fig0035"></elsevierMultimedia></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Carcinoma escamoso cut&#225;neo</span><p id="par0065" class="elsevierStylePara elsevierViewall">Un estudio prospectivo en pacientes con CEC tratados con CMM compar&#243; 38 individuos con m&#225;rgenes de <span class="elsevierStyleItalic">debulking</span> delimitados por fluorescencia vs&#46; 29 delimitados cl&#237;nicamente&#46; El grupo con diagn&#243;stico por fluorescencia requiri&#243; menos estadios de CMM<a class="elsevierStyleCrossRef" href="#bib0725"><span class="elsevierStyleSup">68</span></a>&#46;</p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Enfermedad de Paget extramamaria</span><p id="par0070" class="elsevierStylePara elsevierViewall">La enfermedad de Paget extramamaria &#40;EPE&#41; es una neoplasia intraepitelial infrecuente&#44; y se caracteriza por elevadas tasas de recurrencia a pesar de escisiones extensas o CMM<a class="elsevierStyleCrossRefs" href="#bib0730"><span class="elsevierStyleSup">69-71</span></a>&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">Un estudio prospectivo con 36 pacientes con EPE compar&#243; m&#225;rgenes quir&#250;rgicos delimitados por biopsias sucesivas en la zona de fluorescencia roja tras aplicar 5-ALA y LW vs&#46; ex&#233;resis amplias con 2<span class="elsevierStyleHsp" style=""></span>cm de margen<a class="elsevierStyleCrossRef" href="#bib0740"><span class="elsevierStyleSup">71</span></a>&#46; El grupo con 5-ALA y LW present&#243; &#225;reas de resecci&#243;n significativamente menores&#44; menor tiempo quir&#250;rgico y menores secuelas funcionales&#46; No hubo diferencias en las tasas de recurrencia a los 5 a&#241;os<a class="elsevierStyleCrossRef" href="#bib0740"><span class="elsevierStyleSup">71</span></a>&#46; Otro m&#233;todo consiste en la inyecci&#243;n de fluoresce&#237;na s&#243;dica por v&#237;a intravenosa&#44; que se acumula las dilataciones vasculares subd&#233;rmicas de las zonas afectadas por la EPE y emite fluorescencia verde bajo LW<a class="elsevierStyleCrossRef" href="#bib0745"><span class="elsevierStyleSup">72</span></a>&#46; Un estudio retrospectivo en 8 pacientes con EPE vulvar tratadas mediante vulvectom&#237;a utiliz&#243; este mapeo&#46; Primero se realizaron biopsias de zonas captantes sin afectaci&#243;n macrosc&#243;pica&#44; evidenciando lesiones sat&#233;lites en un 50&#37; de las pacientes&#46; Esto permiti&#243; una mejor delimitaci&#243;n de los m&#225;rgenes de vulvectom&#237;a en un segundo tiempo&#46; Tras una media de 32 meses de seguimiento&#44; ninguna de las pacientes present&#243; recurrencias<a class="elsevierStyleCrossRef" href="#bib0735"><span class="elsevierStyleSup">70</span></a>&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">En nuestra experiencia&#44; la LW puede ser una herramienta valiosa para ayudar a delimitar m&#225;rgenes quir&#250;rgicos de LM y de CBC o CEC&#44; y utilizamos l&#225;mparas LED con UVA365 muy frecuentemente&#46; Sin embargo&#44; puede sobrestimar<a class="elsevierStyleCrossRefs" href="#bib0670"><span class="elsevierStyleSup">57&#44;62&#44;66</span></a> e infraestimar<a class="elsevierStyleCrossRefs" href="#bib0690"><span class="elsevierStyleSup">61&#44;67</span></a> los m&#225;rgenes quir&#250;rgicos en algunos casos y la mayor&#237;a de la evidencia cl&#237;nica proviene de estudios de peque&#241;o tama&#241;o y con metodolog&#237;a heterog&#233;nea&#46; Por este motivo se requieren m&#225;s estudios prospectivos&#44; de mayor tama&#241;o muestral y de metodolog&#237;a homog&#233;nea&#44; para poder realizar recomendaciones al respecto&#46;</p></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Detecci&#243;n de zonas previamente biopsiadas</span><p id="par0085" class="elsevierStylePara elsevierViewall">Uno de los errores m&#233;dicos graves m&#225;s frecuentes en dermatolog&#237;a es extirpar una lesi&#243;n distinta a la previamente biopsiada&#44; por identificar el &#225;rea err&#243;neamente o por no encontrarla<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">73&#44;74</span></a>&#46; La LW puede ayudar a detectar las zonas de biopsias previas&#44; evitando errores quir&#250;rgicos<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">73&#44;74</span></a> &#40;<a class="elsevierStyleCrossRef" href="#fig0035">fig&#46; 7</a> C-D&#41;&#46;</p></span></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Uso de la luz de Wood en la pr&#225;ctica cl&#237;nica</span><p id="par0090" class="elsevierStylePara elsevierViewall">En 2012 la revista canadiense de medicina de familia la situ&#243; en el primer lugar del top 10 de procedimientos diagn&#243;sticos olvidados<a class="elsevierStyleCrossRef" href="#bib0760"><span class="elsevierStyleSup">75</span></a>&#46; Aunque hay estudios que afirman que su uso ha incrementado con el tiempo&#44; la mayor&#237;a alude a su infrautilizaci&#243;n en la pr&#225;ctica cl&#237;nica diaria<a class="elsevierStyleCrossRefs" href="#bib0765"><span class="elsevierStyleSup">76&#44;77</span></a>&#46; Una encuesta realizada en Andaluc&#237;a mostr&#243; que &#250;nicamente el 42&#44;5&#37; de los dermat&#243;logos dispon&#237;a de LW y la usaba&#59; el 26&#37; la ten&#237;a&#44; pero no la usaba&#44; y el 33&#37; no la ten&#237;a a su alcance<a class="elsevierStyleCrossRef" href="#bib0395"><span class="elsevierStyleSup">2</span></a>&#46;</p></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Conclusiones</span><p id="par0095" class="elsevierStylePara elsevierViewall">La LW representa una herramienta fundamental en el arsenal diagn&#243;stico en dermatolog&#237;a&#46; Es una t&#233;cnica r&#225;pida&#44; econ&#243;mica y de f&#225;cil aprendizaje&#46; Puede resaltar caracter&#237;sticas espec&#237;ficas de trastornos pigmentarios&#44; y de dermatosis inflamatorias&#44; infecciosas y parasitarias&#44; proporcionando informaci&#243;n valiosa para el diagn&#243;stico y la planificaci&#243;n terap&#233;utica&#46; Adem&#225;s&#44; podr&#237;a ayudar en la delimitaci&#243;n de los m&#225;rgenes quir&#250;rgicos del LM y del c&#225;ncer cut&#225;neo no melanoma&#44; aunque la evidencia es a&#250;n escasa&#44; y en algunos casos&#44; contradictoria&#46;</p></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Conflicto de intereses</span><p id="par0100" class="elsevierStylePara elsevierViewall">Los autores declaran no tener ning&#250;n conflicto de intereses&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:17 [
        0 => array:3 [
          "identificador" => "xres2271201"
          "titulo" => "Resumen"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1893161"
          "titulo" => "Palabras clave"
        ]
        2 => array:3 [
          "identificador" => "xres2271202"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0010"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec1893160"
          "titulo" => "Keywords"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introducci&#243;n"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Aspectos t&#233;cnicos y dispositivos"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Exploraci&#243;n f&#237;sica"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Precauciones"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Luz de Wood en dermatosis inflamatorias o autoinmunes"
        ]
        9 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Luz de Wood en trastornos pigmentarios"
        ]
        10 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Luz de Wood en infecciones cut&#225;neas"
        ]
        11 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Luz de Wood en parasitosis cut&#225;neas"
        ]
        12 => array:3 [
          "identificador" => "sec0045"
          "titulo" => "Luz de Wood en c&#225;ncer cut&#225;neo y cirug&#237;a dermatol&#243;gica"
          "secciones" => array:5 [
            0 => array:2 [
              "identificador" => "sec0050"
              "titulo" => "Lentigo maligno"
            ]
            1 => array:2 [
              "identificador" => "sec0055"
              "titulo" => "Carcinoma basocelular"
            ]
            2 => array:2 [
              "identificador" => "sec0060"
              "titulo" => "Carcinoma escamoso cut&#225;neo"
            ]
            3 => array:2 [
              "identificador" => "sec0065"
              "titulo" => "Enfermedad de Paget extramamaria"
            ]
            4 => array:2 [
              "identificador" => "sec0070"
              "titulo" => "Detecci&#243;n de zonas previamente biopsiadas"
            ]
          ]
        ]
        13 => array:2 [
          "identificador" => "sec0075"
          "titulo" => "Uso de la luz de Wood en la pr&#225;ctica cl&#237;nica"
        ]
        14 => array:2 [
          "identificador" => "sec0080"
          "titulo" => "Conclusiones"
        ]
        15 => array:2 [
          "identificador" => "sec0085"
          "titulo" => "Conflicto de intereses"
        ]
        16 => array:1 [
          "titulo" => "Bibliograf&#237;a"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2024-04-15"
    "fechaAceptado" => "2024-07-21"
    "PalabrasClave" => array:2 [
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec1893161"
          "palabras" => array:6 [
            0 => "Eritrasma"
            1 => "Cirug&#237;a de Mohs"
            2 => "Luz de Wood"
            3 => "Hipomelanosis macular progresiva"
            4 => "Vit&#237;ligo"
            5 => "Lentigo maligno"
          ]
        ]
      ]
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1893160"
          "palabras" => array:6 [
            0 => "Erythrasma"
            1 => "Mohs surgery"
            2 => "Wood light"
            3 => "Progressive macular hypomelanosis"
            4 => "Vitiligo"
            5 => "Lentigo maligna"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La luz de Wood &#40;LW&#41; es una herramienta diagn&#243;stica &#250;til&#44; econ&#243;mica y de f&#225;cil aprendizaje&#46; A pesar de sus ventajas&#44; el uso de la LW entre los dermat&#243;logos es limitado&#46; En la poroqueratosis&#44; se ha descrito el signo de &#171;collar de diamantes&#187;&#44; correspondiente a la fluorescencia blanca de la escama hiperquerat&#243;sica&#46; Las lesiones subcl&#237;nicas de morfea se observan como m&#225;culas oscuras bien delimitadas&#46; Dentro de los trastornos pigmentarios destaca la fluorescencia azulada del vit&#237;ligo&#44; el aumento del contraste del melasma epid&#233;rmico y la fluorescencia roja foliculocentrada de la hipomelanosis macular progresiva&#46; Respecto a las infecciones cut&#225;neas&#44; el eritrasma presenta una fluorescencia rojo coral&#59; la ti&#241;a versicolor&#44; fluorescencia amarillo-verdosa&#59; la <span class="elsevierStyleItalic">Pseudomonas aeuriginosa</span>&#44; fluorescencia verde&#44; y la escabiosis&#44; fluorescencia blanco-azulada en los surcos acarinos&#46; En el c&#225;ncer cut&#225;neo&#44; la LW se ha empleado para delimitar los m&#225;rgenes quir&#250;rgicos tanto de lentigo maligno como de c&#225;ncer cut&#225;neo no melanoma&#44; con resultados variables&#46;</p></span>"
      ]
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Wood&#39;s light &#40;WL&#41; is a useful&#44; economical and easy-to-learn diagnostic tool&#46; Despite its advantages&#44; the use of LW among dermatologists is limited&#46; In porokeratosis&#44; the &#8220;diamond necklace&#8221; sign has been described&#44; corresponding to the white fluorescence of the hyperkeratotic scale&#46; Subclinical morphea lesions are seen as well-defined dark macules&#46; Among the pigmentary disorders&#44; the bluish fluorescence of vitiligo&#44; the increased contrast of epidermal melasma&#44; and the follicular-centered red fluorescence of progressive macular hypomelanosis stand out&#46; Regarding skin infections&#44; erythrasma presents a coral red fluorescence&#59; tinea versicolor&#44; yellow-green fluorescence&#59; <span class="elsevierStyleItalic">Pseudomonas aeuriginosa</span>&#44; green fluorescence&#59; and scabies&#44; blue-white fluorescence in the acarine grooves&#46; In skin cancer&#44; LW has been used to delimit the surgical margins of both lentigo maligna and non-melanoma skin cancer&#44; with variable results&#46;</p></span>"
      ]
    ]
    "multimedia" => array:8 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Figura 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 2207
            "Ancho" => 2398
            "Tamanyo" => 667302
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A&#41; Poroqueratosis act&#237;nica diseminada B&#41; Luz de Wood&#46; &#171;Collar de diamantes&#187;&#58; fluorescencia blanca de la escama hiperquerat&#243;sica&#46; C&#41; Vit&#237;ligo facial incipiente&#46; D&#41; Se observa un notorio aumento de la visibilidad de las &#225;reas hipopigmentadas con luz de Wood&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Figura 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1773
            "Ancho" => 2398
            "Tamanyo" => 389548
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A&#41; Melasma facial &#40;mejilla&#41;&#46; B&#41; Realce de las zonas hiperpigmentadas con luz de Wood&#46; C&#41; Melasma facial &#40;mejillas y labio superior&#41;&#46; D&#41; Zonas hiperpigmentadas con luz de Wood&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Figura 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 2102
            "Ancho" => 2464
            "Tamanyo" => 498344
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">A&#41; Hipomelanosis macular progresiva&#46; B&#41; Fluorescencia roja en los fol&#237;culos de las zonas hipopigmentadas con luz de Wood &#40;en la realidad es m&#225;s f&#225;cil de apreciar que en la fotograf&#237;a&#41;&#46; C&#41; Pitiriasis versicolor cl&#237;nicamente muy sutil&#46; D&#41; Fluorescencia amarillenta con luz de Wood&#46;</p>"
        ]
      ]
      3 => array:7 [
        "identificador" => "fig0020"
        "etiqueta" => "Figura 4"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr4.jpeg"
            "Alto" => 627
            "Ancho" => 2498
            "Tamanyo" => 209270
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A&#41; Eritrasma inguinal&#46; B&#41; Fluorescencia rojo coral bajo la luz de Wood&#46; C&#41; Eritrasma interdigital en el pie izquierdo&#46; Fluorescencia rojo coral bajo la luz de Wood&#46;</p>"
        ]
      ]
      4 => array:7 [
        "identificador" => "fig0025"
        "etiqueta" => "Figura 5"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr5.jpeg"
            "Alto" => 818
            "Ancho" => 2491
            "Tamanyo" => 152817
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A&#41; S&#237;ndrome de la u&#241;a verde por <span class="elsevierStyleItalic">Pseudomona aeruginosa</span>&#46; B&#41; Surcos acarinos con luz de Wood &#40;flechas blancas&#41;&#46; C&#41; Imagen dermatosc&#243;pica de los surcos acarinos &#40;flechas blancas&#41;&#46;</p>"
        ]
      ]
      5 => array:7 [
        "identificador" => "fig0030"
        "etiqueta" => "Figura 6"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr6.jpeg"
            "Alto" => 1009
            "Ancho" => 2346
            "Tamanyo" => 307609
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">A&#41; Lentigo maligno en el l&#243;bulo de la oreja derecha&#44; muy dif&#237;cil de apreciar y de delimitar&#46; B&#41; Con luz de Wood se logr&#243; una delimitaci&#243;n m&#225;s precisa&#44; permitiendo m&#225;rgenes libres en el primer estadio con cirug&#237;a de Mohs&#46; La flecha negra muestra la zona de biopsia previa&#44; claramente visible bajo luz de Wood&#46;</p>"
        ]
      ]
      6 => array:7 [
        "identificador" => "fig0035"
        "etiqueta" => "Figura 7"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr7.jpeg"
            "Alto" => 2108
            "Ancho" => 2470
            "Tamanyo" => 704265
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">A&#41; Carcinoma basocelular mal delimitado en la zona paranasal izquierda&#46; B&#41; Delimitaci&#243;n prequir&#250;rgica con luz de Wood&#46; C&#41; Cicatriz de melanoma en el antebrazo derecho&#44; previa ampliaci&#243;n de m&#225;rgenes&#46; Dif&#237;cil de detectar cl&#237;nicamente&#46; D&#41; La luz de Wood permite encontrar f&#225;cilmente la cicatriz &#40;flechas negras&#41;&#46;</p>"
        ]
      ]
      7 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Tabla 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Tabla "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">CBC&#58; carcinoma basocelular&#59; CEC&#58; carcinoma escamoso cut&#225;neo&#59; 5-ALA&#58; &#225;cido 5 aminolevul&#237;nico&#46;</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Fuente&#58; Dyer et al&#46;<a class="elsevierStyleCrossRef" href="#bib0465"><span class="elsevierStyleSup">16</span></a>&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Patolog&#237;a&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Hallazgos con luz de Wood&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Dermatosis inflamatorias&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Poroqueratosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Borde blanco azulado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Morfea en placas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">M&#225;cula oscura&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Trastornos pigmentarios&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Hipomelanosis macular progresiva&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia roja centrada en los fol&#237;culos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vit&#237;ligo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Coloraci&#243;n azul&#47;no fluorescencia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Melasma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Epid&#233;rmico&#58; aumento del contraste&#46; D&#233;rmico&#58; no contrasta&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Infecciones&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ti&#241;a versicolor&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia amarillo-verdosa&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Eritrasma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia rojo coral&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Tricobacteriosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Color azulado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Pseudomonas aeruginosa</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia verde&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Microsporum</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia verde-azulado&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleItalic">Trichophyton schoenleinii</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Color azul p&#225;lido&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Parasitosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Escabiosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Surco blanco azulado y &#225;caro verdoso&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">C&#225;ncer cut&#225;neo&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Lentigo maligno&#47;lentigo maligno melanoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Aumento del contraste de pigmentaci&#243;n&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CBC&#47;CEC &#43; 5-ALA&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Coloraci&#243;n rojiza&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Trastornos metab&#243;licos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Porfiria eritropoy&#233;tica cong&#233;nita&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia rojo-rosada en orina&#44; sangre y esmalte dental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Porfiria cut&#225;nea tarda&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia rojo-rosada en orina y heces&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Porfiria hepatoeritropoy&#233;tica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia rojo-rosada en orina&#44; sangre y esmalte dental&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Protoporfiria eritropoy&#233;tica&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Fluorescencia rojo-rosada en sangre&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab3688540.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "es" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Aplicaciones de la luz de Wood en dermatolog&#237;a</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:77 [
            0 => array:3 [
              "identificador" => "bib0390"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Robert Williams Wood&#58; pioneer of invisible light"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Sharma"
                            1 => "A&#46; Sharma"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/phpp.12235"
                      "Revista" => array:5 [
                        "tituloSerie" => "Photodermatol Photoimmunol Photomed&#46;"
                        "fecha" => "2016"
                        "volumen" => "32"
                        "paginaInicial" => "60"
                        "paginaFinal" => "65"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0395"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Encuesta sobre el empleo de la l&#225;mpara de Wood por los dermat&#243;logos andaluces"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46; Tercedor S&#225;nchez"
                            1 => "E&#46; Fern&#225;ndez Vilari&#241;o"
                            2 => "E&#46; Morales Larios"
                            3 => "B&#46; L&#243;pez Hern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2000"
                        "volumen" => "91"
                        "paginaInicial" => "442"
                        "paginaFinal" => "444"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0400"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "UV light set-ups for vitiligo photography&#44; a comparative study on image quality and ease of use"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46;e&#46; Uitentuis"
                            1 => "M&#46;W&#46; Bekkenk"
                            2 => "N&#46; van Geel"
                            3 => "M&#46;A&#46; de Rie"
                            4 => "A&#46; Wolkerstorfer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jdv.15666"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol&#46;"
                        "fecha" => "2019"
                        "volumen" => "33"
                        "paginaInicial" => "1971"
                        "paginaFinal" => "1975"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0405"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "365-nm narrowband Wood&#39;s lamp for vitiligo and hypopigmentation disorders"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Bae"
                            1 => "R&#46;W&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2019.08.064"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2020"
                        "volumen" => "83"
                        "paginaInicial" => "e283"
                        "paginaFinal" => "e284"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0410"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Using a hand-held black-light source instead of a Wood&#39;s lamp"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Kaliyadan"
                            1 => "J&#46; Kuruvilla"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2015.02.1096"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2015"
                        "volumen" => "72"
                        "paginaInicial" => "e153"
                        "paginaFinal" => "e154"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25981019"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0415"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wood&#39;s lamp image of porokeratosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Sun"
                            1 => "H&#46; Chen"
                            2 => "W&#46; Zhu"
                            3 => "S&#46; Lian"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/phpp.12285"
                      "Revista" => array:6 [
                        "tituloSerie" => "Photodermatol Photoimmunol Photomed&#46;"
                        "fecha" => "2017"
                        "volumen" => "33"
                        "paginaInicial" => "114"
                        "paginaFinal" => "116"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27981645"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0420"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Errichetti E&#44; Pietkiewicz P&#44; Bhat YJ&#44; Salwowska N&#44; Szl&#261;zak P&#44; Stinco G&#46; Diagnostic accuracy of ultraviolet-induced fluorescence dermoscopy in non-neoplastic dermatoses &#40;general dermatology&#41;&#58; A multicentric retrospective comparative study&#46; J Eur Acad Dermatol Venereol&#46; 2024&#59;00&#58;1-12&#44; DOI 10&#46;1111&#47;jdv&#46;19795"
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0425"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Review of applications of fluorescence excitation spectroscopy to dermatology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "W&#46; Franco"
                            1 => "E&#46; Gutierrez-Herrera"
                            2 => "N&#46; Kollias"
                            3 => "A&#46; Doukas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/bjd.14221"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol&#46;"
                        "fecha" => "2016"
                        "volumen" => "174"
                        "paginaInicial" => "499"
                        "paginaFinal" => "504"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26471781"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0430"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fluorescence excitation spectroscopy provides information about human skin in vivo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46; Gillies"
                            1 => "G&#46; Zonios"
                            2 => "R&#46; Rox Anderson"
                            3 => "N&#46; Kollias"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1523-1747.2000.00091.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Invest Dermatol&#46;"
                        "fecha" => "2000"
                        "volumen" => "115"
                        "paginaInicial" => "704"
                        "paginaFinal" => "707"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10998147"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0435"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment methods for the evaluation of vitiligo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46;M&#46; Alghamdi"
                            1 => "A&#46; Kumar"
                            2 => "A&#46; Ta&#239;eb"
                            3 => "K&#46; Ezzedine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1468-3083.2012.04505.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol JEADV&#46;"
                        "fecha" => "2012"
                        "volumen" => "26"
                        "paginaInicial" => "1463"
                        "paginaFinal" => "1471"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22416879"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0440"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Subclinical melasma&#58; Determining disease extent"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46;A&#46; Wirya"
                            1 => "M&#46;B&#46; de Castro Maymone"
                            2 => "R&#46; Widjajahakim"
                            3 => "N&#46;A&#46; Vashi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2017.03.009"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2017"
                        "volumen" => "77"
                        "paginaInicial" => "e41"
                        "paginaFinal" => "e42"
                        "itemHostRev" => array:3 [
                          "pii" => "S104727971500215X"
                          "estado" => "S300"
                          "issn" => "10472797"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0445"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wood&#39;s lamp"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Gupta"
                            1 => "M&#46; Singhi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Indian J Dermatol Venereol Leprol&#46;"
                        "fecha" => "2004"
                        "volumen" => "70"
                        "paginaInicial" => "131"
                        "paginaFinal" => "135"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17642589"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0450"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "False &#8220;highlighting&#8221; with Wood&#39;s lamp"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;I&#46; Silverberg"
                            1 => "N&#46;B&#46; Silverberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1525-1470.2012.01787.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "31"
                        "paginaInicial" => "109"
                        "paginaFinal" => "110"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22747772"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0455"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ultraviolet radiation oxidative stress affects eye health"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "I&#46;V&#46; Ivanov"
                            1 => "T&#46; Mappes"
                            2 => "P&#46; Schaupp"
                            3 => "C&#46; Lappe"
                            4 => "S&#46; Wahl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/jbio.201700377"
                      "Revista" => array:3 [
                        "tituloSerie" => "J Biophotonics&#46;"
                        "fecha" => "2018"
                        "volumen" => "11"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0460"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ultraviolet radiation as a risk factor for cataract and macular degeneration"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;E&#46; Roberts"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/ICL.0b013e31821cbcc9"
                      "Revista" => array:5 [
                        "tituloSerie" => "Eye Contact Lens&#46;"
                        "fecha" => "2011"
                        "volumen" => "37"
                        "paginaInicial" => "246"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21617534"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0465"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Revealing the unseen&#58; A review of Wood&#39;s lamp in dermatology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; Dyer"
                            1 => "V&#46;M&#46; Foy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Clin Aesthet Dermatol"
                        "fecha" => "2022"
                        "volumen" => "15"
                        "paginaInicial" => "25"
                        "paginaFinal" => "30"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0470"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ultraviolet protective eyewear for Wood&#39;s light use"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46;M&#46; Herro"
                            1 => "T&#46; Cosan"
                            2 => "S&#46;E&#46; Jacob"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1525-1470.2011.01438.x"
                      "Revista" => array:5 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2011"
                        "volumen" => "28"
                        "paginaInicial" => "351"
                        "paginaFinal" => "352"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0475"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diamond necklace appearance in superficial porokeratosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;S&#46; Thatte"
                            1 => "V&#46;D&#46; Kharkar"
                            2 => "U&#46;S&#46; Khopkar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2013.12.026"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "70"
                        "paginaInicial" => "e125"
                        "paginaFinal" => "e126"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0480"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wood&#39;s lamp as a tool in the evaluation of morphea"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "P&#46; Curtiss"
                            1 => "G&#46; Singh"
                            2 => "K&#46; lo Sicco"
                            3 => "A&#46;G&#46; Franks"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2017.10.003"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2018"
                        "volumen" => "78"
                        "paginaInicial" => "e33"
                        "paginaFinal" => "e34"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0485"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "100 years of Wood&#39;s lamp revised"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;l&#46; Klatte"
                            1 => "N&#46; van der Beek"
                            2 => "P&#46;M&#46;J&#46;H&#46; Kemperman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jdv.12860"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol&#46;"
                        "fecha" => "2015"
                        "volumen" => "29"
                        "paginaInicial" => "842"
                        "paginaFinal" => "847"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0490"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Non-invasive skin measurement methods and diagnostics for vitiligo&#58; A systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "P&#46; Abdi"
                            1 => "M&#46;R&#46; Anthony"
                            2 => "C&#46; Farkouh"
                            3 => "A&#46;R&#46; Chan"
                            4 => "A&#46; Kooner"
                            5 => "S&#46; Qureshi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3389/fmed.2023.1200963"
                      "Revista" => array:3 [
                        "tituloSerie" => "Front Med&#46;"
                        "fecha" => "2023"
                        "volumen" => "10"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0495"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Subjective versus objective recognition of facial vitiligo lesions&#58; Detection of subclinical lesions by Wood&#39;s light"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46;S&#46; Anbar"
                            1 => "M&#46;A&#46; Atwa"
                            2 => "R&#46;T&#46; Abdel-Aziz"
                            3 => "R&#46;A&#46; Hegazy"
                            4 => "S&#46;I&#46; Ibrahim"
                            5 => "R&#46;M&#46; El Genedy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/jewd.jewd_42_21"
                      "Revista" => array:4 [
                        "tituloSerie" => "J Egypt Women&#39;s Dermatol Soc&#46;"
                        "fecha" => "2022"
                        "volumen" => "19"
                        "paginaInicial" => "7"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0500"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wood&#39;s lamp for vitiligo disease stability and early recognition of initiative pigmentation after epidermal grafting"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "Y&#46; Wang"
                            1 => "C&#46; Chang"
                            2 => "K&#46; Cheng"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/iwj.12800"
                      "Revista" => array:5 [
                        "tituloSerie" => "Int Wound J&#46;"
                        "fecha" => "2017"
                        "volumen" => "14"
                        "paginaInicial" => "1391"
                        "paginaFinal" => "1394"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0505"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tuberous sclerosis complex&#58; An update for dermatologists"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;K&#46; Jacks"
                            1 => "P&#46;M&#46; Witman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/pde.12567"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2015"
                        "volumen" => "32"
                        "paginaInicial" => "563"
                        "paginaFinal" => "570"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25776100"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0510"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Skin lesions in children with tuberous sclerosis complex&#58; Their prevalence&#44; natural course&#44; and diagnostic significance"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; J&#243;z&#176;wiak"
                            1 => "R&#46;A&#46; Schwartz"
                            2 => "C&#46;K&#46; Janniger"
                            3 => "R&#46; Micha&#322;owicz"
                            4 => "J&#46; Chmielik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1365-4362.1998.00495.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol&#46;"
                        "fecha" => "1998"
                        "volumen" => "37"
                        "paginaInicial" => "911"
                        "paginaFinal" => "917"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9888331"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0515"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The cutaneous features of tuberous sclerosis&#58; A population study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "D&#46;W&#46; Webb"
                            1 => "A&#46; Carke"
                            2 => "A&#46; Fyer"
                            3 => "J&#46;P&#46; Osborne"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1365-2133.1996.d01-923.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol&#46;"
                        "fecha" => "1996"
                        "volumen" => "135"
                        "paginaInicial" => "1"
                        "paginaFinal" => "5"
                        "itemHostRev" => array:3 [
                          "pii" => "S0735109715075452"
                          "estado" => "S300"
                          "issn" => "07351097"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0520"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melasma&#58; A clinicopathological study of 43 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "V&#46; Sarvjot"
                            1 => "S&#46; Sharma"
                            2 => "S&#46; Mishra"
                            3 => "A&#46; Singh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/0377-4929.54993"
                      "Revista" => array:4 [
                        "tituloSerie" => "Indian J Pathol Microbiol&#46;"
                        "fecha" => "2009"
                        "volumen" => "52"
                        "paginaInicial" => "357"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0525"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melasma treatment&#58; A systematic review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "N&#46; Neagu"
                            1 => "C&#46; Conforti"
                            2 => "M&#46; Agozzino"
                            3 => "G&#46;F&#46; Marangi"
                            4 => "S&#46;H&#46; Morariu"
                            5 => "G&#46; Pellacani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/09546634.2021.1914313"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol Treat&#46;"
                        "fecha" => "2022"
                        "volumen" => "33"
                        "paginaInicial" => "1816"
                        "paginaFinal" => "1837"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0530"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The dermoscopic characteristics of melasma in relation to different skin phototypes&#44; distribution patterns and wood lamp findings&#58; A cross-sectional study of 236 melasma lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46; Bostan"
                            1 => "A&#46; Cakir"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00403-023-02584-8"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol Res&#46;"
                        "fecha" => "2023"
                        "volumen" => "315"
                        "paginaInicial" => "1927"
                        "paginaFinal" => "1938"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/36853510"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0535"
              "etiqueta" => "30"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melasma in men&#58; A clinical&#44; aetiological and histological study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "R&#46; Sarkar"
                            1 => "P&#46; Puri"
                            2 => "R&#46; Jain"
                            3 => "A&#46; Singh"
                            4 => "A&#46; Desai"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1468-3083.2009.03524.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol&#46;"
                        "fecha" => "2010"
                        "volumen" => "24"
                        "paginaInicial" => "768"
                        "paginaFinal" => "772"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20015053"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0540"
              "etiqueta" => "31"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Melasma&#58; Treatment strategy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "V&#46;N&#46; Sehgal"
                            1 => "P&#46; Verma"
                            2 => "G&#46; Srivastava"
                            3 => "A&#46;K&#46; Aggarwal"
                            4 => "S&#46; Verma"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/14764172.2011.630088"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Cosmet Laser Ther&#46;"
                        "fecha" => "2011"
                        "volumen" => "13"
                        "paginaInicial" => "265"
                        "paginaFinal" => "279"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0545"
              "etiqueta" => "32"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Heterogeneous pathology of melasma and its clinical implications"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46;H&#46; Kwon"
                            1 => "Y&#46;J&#46; Hwang"
                            2 => "S&#46;K&#46; Lee"
                            3 => "K&#46;C&#46; Park"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3390/ijms17060824"
                      "Revista" => array:4 [
                        "tituloSerie" => "Int J Mol Sci&#46;"
                        "fecha" => "2016"
                        "volumen" => "17"
                        "paginaInicial" => "824"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0550"
              "etiqueta" => "33"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Propionibacterium acnes and the pathogenesis of progressive macular hypomelanosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "W&#46; Westerhof"
                            1 => "G&#46;N&#46; Relyveld"
                            2 => "M&#46;M&#46; Kingswijk"
                            3 => "P&#46; de Man"
                            4 => "H&#46;E&#46; Menke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1001/archderm.140.2.210"
                      "Revista" => array:7 [
                        "tituloSerie" => "Arch Dermatol&#46;"
                        "fecha" => "2004"
                        "volumen" => "140"
                        "paginaInicial" => "210"
                        "paginaFinal" => "214"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14967796"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S1751991818302456"
                          "estado" => "S300"
                          "issn" => "17519918"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0555"
              "etiqueta" => "34"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical&#44; pathologic&#44; and ultrastructural studies of progressive macular hypomelanosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "W&#46;X&#46; Gang"
                            1 => "A&#46; Xu"
                            2 => "X&#46;Z&#46; Song"
                            3 => "J&#46;H&#46; Zheng"
                            4 => "P&#46; Wang"
                            5 => "H&#46; Shen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2010.04492.x"
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Dermatol&#46;"
                        "fecha" => "2010"
                        "volumen" => "49"
                        "paginaInicial" => "1127"
                        "paginaFinal" => "1132"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0560"
              "etiqueta" => "35"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Progressive macular hypomelanosis&#58; An overview"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46;N&#46; Relyveld"
                            1 => "H&#46;E&#46; Menke"
                            2 => "W&#46; Westerhof"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2165/00128071-200708010-00002"
                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Clin Dermatol&#46;"
                        "fecha" => "2007"
                        "volumen" => "8"
                        "paginaInicial" => "13"
                        "paginaFinal" => "19"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0565"
              "etiqueta" => "36"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is Cutibacterium &#40;previously Propionibacterium&#41; acnes a potential pathogenic factor in the aetiology of the skin disease progressive macular hypomelanosis&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; McDowell"
                            1 => "J&#46; McLaughlin"
                            2 => "A&#46;M&#46; Layton"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/jdv.16789"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol&#46;"
                        "fecha" => "2021"
                        "volumen" => "35"
                        "paginaInicial" => "338"
                        "paginaFinal" => "344"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0570"
              "etiqueta" => "37"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical and epidemiological features of coryneform skin infections at a tertiary hospital"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Pinto"
                            1 => "G&#46;K&#46; Hundi"
                            2 => "R&#46;M&#46; Bhat"
                            3 => "N&#46;K&#46; Bala"
                            4 => "S&#46; Dankeri"
                            5 => "J&#46; Martis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/2229-5178.182351"
                      "Revista" => array:5 [
                        "tituloSerie" => "Indian Dermatol Online J&#46;"
                        "fecha" => "2016"
                        "volumen" => "7"
                        "paginaInicial" => "168"
                        "paginaFinal" => "173"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0575"
              "etiqueta" => "38"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Eritrasma interdigital&#58; datos cl&#237;nicos&#44; epidemiol&#243;gicos y microbiol&#243;gicos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;L&#46; Morales-Trujillo"
                            1 => "R&#46; Arenas"
                            2 => "S&#46; Arroyo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0001-7310(08)74718-5"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2008"
                        "volumen" => "99"
                        "paginaInicial" => "469"
                        "paginaFinal" => "473"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18558055"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            38 => array:3 [
              "identificador" => "bib0580"
              "etiqueta" => "39"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Montes de Oca-Loyola ML&#44; Lumb&#225;n Ram&#237;rez P&#44; G&#243;mez-Daza F&#44; Bonifaz A&#46; An overview of Trichobacteriosis &#40;Trichomycosis&#41;&#58; An underdiagnosed disease&#46; Cureus&#46; 2023&#59;15&#40;9&#41;&#58;e45964&#46; doi&#58; 10&#46;7759&#47;cureus&#46;45964&#46;"
                ]
              ]
            ]
            39 => array:3 [
              "identificador" => "bib0585"
              "etiqueta" => "40"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Trichomycosis axillaris&#58; Clinical&#44; Wood lamp&#44; and dermoscopic diagnostic images"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "E&#46; Rojas Mora"
                            1 => "A&#46; Freites Mart&#237;nez"
                            2 => "A&#46; Hern&#225;ndez-N&#250;&#241;ez"
                            3 => "J&#46; Borbujo Mart&#237;nez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.adengl.2017.02.017"
                      "Revista" => array:5 [
                        "tituloSerie" => "Actas Dermo-Sifiliogr&#225;ficas Engl Ed&#46;"
                        "fecha" => "2017"
                        "volumen" => "108"
                        "paginaInicial" => "264"
                        "paginaFinal" => "265"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            40 => array:3 [
              "identificador" => "bib0590"
              "etiqueta" => "41"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Ultraviolet-induced fluorescence dermatoscopy of trichobacteriosis axillaris reveals peripilar yellow-green luminescent concretions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; Al-Nasiri"
                            1 => "C&#46; Navarrete-Dechent"
                            2 => "K&#46; Korecka"
                            3 => "N&#46; Salwowska"
                            4 => "M&#46; Goldust"
                            5 => "P&#46; Pietkiewicz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5826/dpc.1302a169"
                      "Revista" => array:4 [
                        "tituloSerie" => "Dermatol Pract Concept&#46;"
                        "fecha" => "2023"
                        "volumen" => "13"
                        "paginaInicial" => "e2023169"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            41 => array:3 [
              "identificador" => "bib0595"
              "etiqueta" => "42"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pityrialactone &#8212;a new fluorochrome from the tryptophan metabolism of Malassezia furfur"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "P&#46; Mayser"
                            1 => "H&#46; Stapelkamp"
                            2 => "H&#46;J&#46; Kr&#228;mer"
                            3 => "M&#46; Podobinska"
                            4 => "W&#46; Wallbott"
                            5 => "B&#46; Irlinger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1023/a:1026042903354"
                      "Revista" => array:5 [
                        "tituloSerie" => "Antonie Van Leeuwenhoek&#46;"
                        "fecha" => "2003"
                        "volumen" => "84"
                        "paginaInicial" => "185"
                        "paginaFinal" => "191"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            42 => array:3 [
              "identificador" => "bib0600"
              "etiqueta" => "43"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Identification and Speciation of Malassezia in patients clinically suspected of having pityriasis versicolor"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; Shah"
                            1 => "A&#46; Koticha"
                            2 => "M&#46; Ubale"
                            3 => "S&#46; Wanjare"
                            4 => "P&#46; Mehta"
                            5 => "U&#46; Khopkar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/0019-5154.110841"
                      "Revista" => array:4 [
                        "tituloSerie" => "Indian J Dermatol&#46;"
                        "fecha" => "2013"
                        "volumen" => "58"
                        "paginaInicial" => "239"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            43 => array:3 [
              "identificador" => "bib0605"
              "etiqueta" => "44"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Differentially expressed genes associated with tryptophan-dependent pigment synthesis in Malassezia furfur &#8212;a comparison with the recently published genome of Malassezia globosa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;K&#46; Lang"
                            1 => "W&#46; Hort"
                            2 => "P&#46; Mayser"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1439-0507.2009.01848.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycoses&#46;"
                        "fecha" => "2011"
                        "volumen" => "54"
                        "paginaInicial" => "e69"
                        "paginaFinal" => "e83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20202114"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            44 => array:3 [
              "identificador" => "bib0610"
              "etiqueta" => "45"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Usefulness of topical efinaconazole for infantile tinea capitis due to Microsporum canis diagnosed with Wood&#39;s light"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46; Komatsu-Fujii"
                            1 => "S&#46; Nonoyama"
                            2 => "M&#46; Ogawa"
                            3 => "T&#46; Fukumoto"
                            4 => "T&#46; Ookura"
                            5 => "K&#46; Anzawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/1346-8138.15555"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Dermatol&#46;"
                        "fecha" => "2020"
                        "volumen" => "47"
                        "paginaInicial" => "e401"
                        "paginaFinal" => "e403"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32794269"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            45 => array:3 [
              "identificador" => "bib0615"
              "etiqueta" => "46"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tinea capitis in children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:5 [
                            0 => "N&#46; Vargas-Navia"
                            1 => "G&#46;A&#46; Ayala Monroy"
                            2 => "C&#46; Franco R&#250;a"
                            3 => "J&#46;P&#46; Malag&#243;n Caicedo"
                            4 => "J&#46;P&#46; Rojas Hern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.32641/rchped.vi91i5.1345"
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Chil Pediatr&#237;a&#46;"
                        "fecha" => "2020"
                        "volumen" => "91"
                        "paginaInicial" => "773"
                        "paginaFinal" => "783"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            46 => array:3 [
              "identificador" => "bib0620"
              "etiqueta" => "47"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tinea capitis by Microsporum canis in an elderly female with extensive dermatophyte infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Z&#46; Yang"
                            1 => "W&#46; Chen"
                            2 => "Z&#46; Wan"
                            3 => "Y&#46; Song"
                            4 => "R&#46; Li"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11046-020-00519-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycopathologia&#46;"
                        "fecha" => "2021"
                        "volumen" => "186"
                        "paginaInicial" => "299"
                        "paginaFinal" => "305"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/33496917"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            47 => array:3 [
              "identificador" => "bib0625"
              "etiqueta" => "48"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pediatric tinea capitis in Jilin Province&#58; Analyzing previous results from a new perspective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Zeng"
                            1 => "S&#46; Wang"
                            2 => "L&#46; Guo"
                            3 => "S&#46; Lv"
                            4 => "B&#46; Shan"
                            5 => "Z&#46; Liu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11046-023-00718-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mycopathologia&#46;"
                        "fecha" => "2023"
                        "volumen" => "188"
                        "paginaInicial" => "515"
                        "paginaFinal" => "522"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/37022619"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            48 => array:3 [
              "identificador" => "bib0630"
              "etiqueta" => "49"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Early detection of Pseudomonas infection using a Wood&#39;s lamp"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "B&#46; Amichai"
                            1 => "E&#46; Finkelsten"
                            2 => "S&#46; Halevy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2230.1994.tb02713.x"
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Exp Dermatol&#46;"
                        "fecha" => "1994"
                        "volumen" => "19"
                        "paginaInicial" => "449"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7955517"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            49 => array:3 [
              "identificador" => "bib0635"
              "etiqueta" => "50"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A review of Pseudomonas aeruginosa Metallophores&#58; Pyoverdine&#44; pyochelin and pseudopaline"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46; Ghssein"
                            1 => "Z&#46; Ezzeddine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3390/biology11121711"
                      "Revista" => array:4 [
                        "tituloSerie" => "Biology&#46;"
                        "fecha" => "2022"
                        "volumen" => "11"
                        "paginaInicial" => "1711"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            50 => array:3 [
              "identificador" => "bib0640"
              "etiqueta" => "51"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Visual Dermatology&#58; Using Wood&#39;s lamp to detect early infection by Pseudomonas aeruginosa"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Reis"
                            1 => "G&#46; Cunha Velho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1177/1203475420915442"
                      "Revista" => array:4 [
                        "tituloSerie" => "J Cutan Med Surg&#46;"
                        "fecha" => "2020"
                        "volumen" => "24"
                        "paginaInicial" => "308"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            51 => array:3 [
              "identificador" => "bib0645"
              "etiqueta" => "52"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Utility of Wood&#39;s Lamp in Intertrigo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46; Agrawal"
                            1 => "M&#46; Panda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/idoj.IDOJ_957_20"
                      "Revista" => array:6 [
                        "tituloSerie" => "Indian Dermatol Online J&#46;"
                        "fecha" => "2021"
                        "volumen" => "12"
                        "paginaInicial" => "948"
                        "paginaFinal" => "949"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34934747"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            52 => array:3 [
              "identificador" => "bib0650"
              "etiqueta" => "53"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Using ultraviolet dermoscopy in diagnosing scabies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; Y&#252;rekli"
                            1 => "&#304;&#46; Muslu"
                            2 => "S&#46;D&#46; Pekta&#351;"
                            3 => "E&#46;T&#46; Alata&#351;"
                            4 => "C&#46;T&#46; Aydo&#287;du"
                            5 => "D&#46; Da&#351;gin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/exd.14930"
                      "Revista" => array:5 [
                        "tituloSerie" => "Exp Dermatol&#46;"
                        "fecha" => "2023"
                        "volumen" => "32"
                        "paginaInicial" => "1996"
                        "paginaFinal" => "1999"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            53 => array:3 [
              "identificador" => "bib0655"
              "etiqueta" => "54"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Facilitations in the clinical diagnosis of human scabies through the use of ultraviolet light &#40;UV-Scab Scanning&#41;&#58; A case-series study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "G&#46; Scanni"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3390/tropicalmed7120422"
                      "Revista" => array:5 [
                        "tituloSerie" => "Trop Med Infect Dis&#46;"
                        "fecha" => "2022"
                        "volumen" => "7"
                        "paginaInicial" => "422"
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673611607496"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            54 => array:3 [
              "identificador" => "bib0660"
              "etiqueta" => "55"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Excision margins for melanoma in situ on the head and neck &#8212;A single-center 10-year retrospective review of treatment with Mohs micrographic surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;A&#46; Tate"
                            1 => "A&#46; Matsumoto"
                            2 => "C&#46; Greif"
                            3 => "J&#46; Lim"
                            4 => "R&#46;I&#46; Nijhawan"
                            5 => "D&#46; Srivastava"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2023.12.063"
                      "Revista" => array:5 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2024"
                        "volumen" => "90"
                        "paginaInicial" => "1226"
                        "paginaFinal" => "1231"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            55 => array:3 [
              "identificador" => "bib0665"
              "etiqueta" => "56"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Defining surgical margins with Wood lamp"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;A&#46; Atwan"
                            1 => "S&#46; Ziaj"
                            2 => "C&#46;M&#46; Mills"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5826/dpc.1001a18"
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Pract Concept&#46;"
                        "fecha" => "2019"
                        "volumen" => "10"
                        "paginaInicial" => "e2020018"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31921505"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            56 => array:3 [
              "identificador" => "bib0670"
              "etiqueta" => "57"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Utility of Wood&#39;s light in margin determination of melanoma in situ after excisional biopsy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46;B&#46; Walsh"
                            1 => "R&#46; Varma"
                            2 => "D&#46; Raimer"
                            3 => "J&#46;C&#46; Keane"
                            4 => "A&#46; Cantor"
                            5 => "A&#46; Theos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000000345"
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2015"
                        "volumen" => "41"
                        "paginaInicial" => "572"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25915625"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            57 => array:3 [
              "identificador" => "bib0675"
              "etiqueta" => "58"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Utility of the Wood&#39;s light&#58; Five cases from a pigmented lesion clinic"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46;R&#46; Paraskevas"
                            1 => "A&#46;C&#46; Halpern"
                            2 => "A&#46;A&#46; Marghoob"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2005.06346.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol&#46;"
                        "fecha" => "2005"
                        "volumen" => "152"
                        "paginaInicial" => "1039"
                        "paginaFinal" => "1044"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15888167"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            58 => array:3 [
              "identificador" => "bib0680"
              "etiqueta" => "59"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Uso de la luz de Wood para la delimitaci&#243;n de m&#225;rgenes quir&#250;rgicos en el lentigo maligno y el lentigo maligno melanoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "I&#46; Navarro-Navarro"
                            1 => "A&#46; Ortiz-Prieto"
                            2 => "I&#46; Villegas-Romero"
                            3 => "S&#46; Valenzuela-Ubi&#241;a"
                            4 => "M&#46; Linares-Barrios"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2021.06.011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2022"
                        "volumen" => "113"
                        "paginaInicial" => "642"
                        "paginaFinal" => "645"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35305779"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            59 => array:3 [
              "identificador" => "bib0685"
              "etiqueta" => "60"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodynamic therapy with endogenous protoporphyrin&#58; IX&#58; Basic principles and present clinical experience"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;C&#46; Kennedy"
                            1 => "R&#46;H&#46; Pottier"
                            2 => "D&#46;C&#46; Pross"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/1011-1344(90)85083-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Photochem Photobiol B&#46;"
                        "fecha" => "1990"
                        "volumen" => "6"
                        "paginaInicial" => "143"
                        "paginaFinal" => "148"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2121931"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            60 => array:3 [
              "identificador" => "bib0690"
              "etiqueta" => "61"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Can basal cell carcinoma lateral border be determined by fluorescence diagnosis&#63;&#58; Verification by Mohs micrographic surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "K&#46; El Hoshy"
                            1 => "M&#46; Bosseila"
                            2 => "D&#46; el Sharkawy"
                            3 => "R&#46; Sobhi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.pdpdt.2016.01.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Photodiagnosis Photodyn Ther&#46;"
                        "fecha" => "2016"
                        "volumen" => "14"
                        "paginaInicial" => "4"
                        "paginaFinal" => "8"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26790611"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            61 => array:3 [
              "identificador" => "bib0695"
              "etiqueta" => "62"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "No clinical benefit of preoperative fluorescence diagnosis of basal cell carcinoma localized in the H-zone of the face"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "T&#46; Wetzig"
                            1 => "M&#46; Kendler"
                            2 => "J&#46; Maschke"
                            3 => "U&#46; Paasch"
                            4 => "J&#46;C&#46; Simon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2010.09666.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol&#46;"
                        "fecha" => "2010"
                        "volumen" => "162"
                        "paginaInicial" => "1370"
                        "paginaFinal" => "1376"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20302577"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            62 => array:3 [
              "identificador" => "bib0700"
              "etiqueta" => "63"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Usefulness of in vivo photodiagnosis for the identification of tumor margins in recurrent basal cell carcinoma of the face"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "R&#46;G&#46; Borroni"
                            1 => "S&#46; Barruscotti"
                            2 => "A&#46; Carugno"
                            3 => "V&#46; Barbaccia"
                            4 => "E&#46; Arbustini"
                            5 => "V&#46; Brazzelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/phpp.12166"
                      "Revista" => array:5 [
                        "tituloSerie" => "Photodermatol Photoimmunol Photomed&#46;"
                        "fecha" => "2015"
                        "volumen" => "31"
                        "paginaInicial" => "195"
                        "paginaFinal" => "201"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            63 => array:3 [
              "identificador" => "bib0705"
              "etiqueta" => "64"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bispectral fluorescence imaging of aggressive basal cell carcinoma combined with histopathological mapping&#58; A preliminary study indicating a possible adjunct to Mohs micrographic surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46; Stenquist"
                            1 => "M&#46;B&#46; Ericson"
                            2 => "C&#46; Strandeberg"
                            3 => "L&#46; M&#246;lne"
                            4 => "A&#46; Ros&#233;n"
                            5 => "O&#46; Lark&#246;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2005.07035.x"
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Dermatol&#46;"
                        "fecha" => "2006"
                        "volumen" => "154"
                        "paginaInicial" => "305"
                        "paginaFinal" => "309"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            64 => array:3 [
              "identificador" => "bib0710"
              "etiqueta" => "65"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "In vivo detection of basal cell carcinoma using imaging spectroscopy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46;M&#46; Wennberg"
                            1 => "F&#46; Gudmundson"
                            2 => "B&#46; Stenquist"
                            3 => "A&#46; Ternesten"
                            4 => "L&#46; M&#246;lne"
                            5 => "A&#46; Ros&#233;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1080/000155599750011723"
                      "Revista" => array:6 [
                        "tituloSerie" => "Acta Derm Venereol&#46;"
                        "fecha" => "1999"
                        "volumen" => "79"
                        "paginaInicial" => "54"
                        "paginaFinal" => "61"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10086861"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            65 => array:3 [
              "identificador" => "bib0715"
              "etiqueta" => "66"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Photodetection of basal cell carcinoma using methyl 5-aminolaevulinate-induced protoporphyrin IX based on fluorescence image analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "Y&#46; Won"
                            1 => "S&#46;H&#46; Hong"
                            2 => "H&#46;Y&#46; Yu"
                            3 => "Y&#46;H&#46; Kwon"
                            4 => "S&#46;J&#46; Yun"
                            5 => "S&#46;C&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2230.2007.02435.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Exp Dermatol&#46;"
                        "fecha" => "2007"
                        "volumen" => "32"
                        "paginaInicial" => "423"
                        "paginaFinal" => "429"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17459066"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            66 => array:3 [
              "identificador" => "bib0720"
              "etiqueta" => "67"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preoperative assessment of basal cell carcinoma using conventional fluorescence diagnosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Neus"
                            1 => "T&#46; Gambichler"
                            2 => "F&#46;G&#46; Bechara"
                            3 => "S&#46; W&#246;hl"
                            4 => "P&#46; Lehmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00403-008-0911-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol Res&#46;"
                        "fecha" => "2009"
                        "volumen" => "301"
                        "paginaInicial" => "289"
                        "paginaFinal" => "294"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18979108"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            67 => array:3 [
              "identificador" => "bib0725"
              "etiqueta" => "68"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of photodynamic diagnosis-guided mohs micrographic surgery in primary squamous cell carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;Y&#46; Jeon"
                            1 => "K&#46;H&#46; Kim"
                            2 => "K&#46;H&#46; Song"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/dsu.12359"
                      "Revista" => array:5 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2013"
                        "volumen" => "39"
                        "paginaInicial" => "1774"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24299572"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            68 => array:3 [
              "identificador" => "bib0730"
              "etiqueta" => "69"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mammary and extramammary Paget&#39;s disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Kanitakis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1468-3083.2007.02154.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Eur Acad Dermatol Venereol&#46;"
                        "fecha" => "2007"
                        "volumen" => "21"
                        "paginaInicial" => "581"
                        "paginaFinal" => "590"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17447970"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            69 => array:3 [
              "identificador" => "bib0735"
              "etiqueta" => "70"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fluorescein mapping in vulvar Paget disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "M&#46;K&#46; Wagar"
                            1 => "R&#46;C&#46; Zhang"
                            2 => "P&#46; Weisman"
                            3 => "R&#46;J&#46; Spencer"
                            4 => "D&#46;M&#46; Kushner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/AOG.0000000000005084"
                      "Revista" => array:5 [
                        "tituloSerie" => "Obstet Gynecol&#46;"
                        "fecha" => "2023"
                        "volumen" => "141"
                        "paginaInicial" => "608"
                        "paginaFinal" => "612"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            70 => array:3 [
              "identificador" => "bib0740"
              "etiqueta" => "71"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The application of Wood&#39;s lamp combined with 5-aminolevulinic acid for defining tumor margins in patients with extramammary Paget&#39;s disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46; Zhou"
                            1 => "J&#46; Li"
                            2 => "C&#46; Song"
                            3 => "Y&#46; Lou"
                            4 => "B&#46; Fu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.pdpdt.2021.102490"
                      "Revista" => array:5 [
                        "tituloSerie" => "Photodiagnosis Photodyn Ther&#46;"
                        "fecha" => "2021"
                        "volumen" => "35"
                        "paginaInicial" => "102490"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34419676"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            71 => array:3 [
              "identificador" => "bib0745"
              "etiqueta" => "72"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vulvar Paget disease&#58; Fluorescein-aided visualization of margins"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;E&#46; Misas"
                            1 => "C&#46;J&#46; Cold"
                            2 => "F&#46;W&#46; Hall"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Obstet Gynecol&#46;"
                        "fecha" => "1991"
                        "volumen" => "77"
                        "paginaInicial" => "156"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1845778"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            72 => array:3 [
              "identificador" => "bib0750"
              "etiqueta" => "73"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The use of a portable black light &#40;UV-A&#41; flashlight to aid in biopsy site identification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;H&#46; Yu"
                            1 => "D&#46;J&#46; Leffell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2021.06.881"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2022"
                        "volumen" => "87"
                        "paginaInicial" => "e143"
                        "paginaFinal" => "e144"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34256036"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            73 => array:3 [
              "identificador" => "bib0755"
              "etiqueta" => "74"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "How we do it&#58; Handheld Wood&#39;s flashlight for surgical site identification before Mohs surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;H&#46; Abdulhak"
                            1 => "S&#46;K&#46; Que"
                            2 => "A&#46;K&#46; Somani"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/DSS.0000000000003877"
                      "Revista" => array:4 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2023"
                        "volumen" => "49"
                        "paginaInicial" => "964"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            74 => array:3 [
              "identificador" => "bib0760"
              "etiqueta" => "75"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Top 10 forgotten diagnostic procedures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46; Ponka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Can Fam Physician&#46;"
                        "fecha" => "2012"
                        "volumen" => "58"
                        "paginaInicial" => "975"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22972729"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            75 => array:3 [
              "identificador" => "bib0765"
              "etiqueta" => "76"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wood&#39;s lamp in dermatology&#58; Applications in the daily practice"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;V&#46; Veasey"
                            1 => "B&#46;A&#46; Fraletti Miguel"
                            2 => "R&#46;B&#46; Bedrikow"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.5935/scd1984-8773.201794964"
                      "Revista" => array:5 [
                        "tituloSerie" => "Surg Cosmet Dermatol&#46;"
                        "fecha" => "2017"
                        "volumen" => "9"
                        "paginaInicial" => "328"
                        "paginaFinal" => "330"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            76 => array:3 [
              "identificador" => "bib0770"
              "etiqueta" => "77"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Wood&#39;s light in dermatology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Asawanonda"
                            1 => "C&#46;R&#46; Taylor"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1365-4362.1999.00794.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Dermatol&#46;"
                        "fecha" => "1999"
                        "volumen" => "38"
                        "paginaInicial" => "801"
                        "paginaFinal" => "807"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10583611"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/00017310/unassign/S0001731024007166/v1_202410150415/es/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/00017310/unassign/S0001731024007166/v1_202410150415/es/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731024007166?idApp=UINPBA000044"
]