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y m&#225;s externamente&#44; otro halo perif&#233;rico rojizo homog&#233;neo que respetaba las unidades foliculares &#40;<a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Diagn&#243;stico</span><p id="par0020" class="elsevierStylePara elsevierViewall">Hemangioma hemosider&#243;tico targetoide &#40;HHT&#41;&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Comentario</span><p id="par0025" class="elsevierStylePara elsevierViewall">El HHT fue descrito por Santa Cruz y Aronberg en 1988&#46; Es una lesi&#243;n vascular benigna que aparece en el tronco y las piernas de pacientes de edad media &#40;30-40 a&#241;os&#41;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a>&#46; 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el HHT suele presentarse como una p&#225;pula rojo-viol&#225;cea&#44; rodeada de un halo perif&#233;rico de aspecto purp&#250;rico&#44; equim&#243;tico&#46; Puede o no acompa&#241;arse de s&#237;ntomas como picor o dolor&#46; Aunque lo m&#225;s frecuente es la presencia de una lesi&#243;n solitaria&#44; se ha descrito la presencia de m&#250;ltiples lesiones simult&#225;neas en un mismo paciente&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">El HHT muestra un patr&#243;n dermatosc&#243;pico muy caracter&#237;stico&#44; como se ha descrito en la <a class="elsevierStyleCrossRef" href="#fig0010">figura 2</a>&#46; Seg&#250;n el estudio de la serie m&#225;s larga hasta la fecha descrita con un total de 35 casos<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">5</span></a>&#44; la dermatoscopia muestra en el 71&#44;4&#37; lagunas rojas y oscuras centrales y un &#225;rea homog&#233;nea circular perif&#233;rica rojiza-viol&#225;cea&#46; En nuestro paciente&#44; 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Dermatoscopia práctica
Pápula violácea en tronco
Violaceous Papule on the Trunk
F.J. Navarro Triviño
Servicio de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario San Cecilio, Granada, España
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          "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">P&#225;pula viol&#225;cea en tronco posterior rodeada de halo purp&#250;rico homog&#233;neo&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Caso cl&#237;nico</span><p id="par0005" class="elsevierStylePara elsevierViewall">Una mujer de 43 a&#241;os&#44; sin antecedentes personales ni familiares de inter&#233;s&#44; fue derivada por su m&#233;dico de atenci&#243;n primaria por una lesi&#243;n viol&#225;cea pruriginosa en tronco posterior de 2 semanas de evoluci&#243;n&#44; con la sospecha de melanoma&#46; La paciente refiri&#243; haber observado un sangrado espont&#225;neo de la lesi&#243;n&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">En la exploraci&#243;n se observ&#243; una p&#225;pula viol&#225;cea rodeada de un halo de aspecto purp&#250;rico &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46; La dermatoscopia mostr&#243; una estructura central rojo-viol&#225;cea y blanquecina de aspecto&#44; rodeada de un halo amarillo-anaranjado&#44; y m&#225;s externamente&#44; otro halo perif&#233;rico rojizo homog&#233;neo que respetaba las unidades foliculares &#40;<a class="elsevierStyleCrossRef" href="#fig0010">fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Diagn&#243;stico</span><p id="par0020" class="elsevierStylePara elsevierViewall">Hemangioma hemosider&#243;tico targetoide &#40;HHT&#41;&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Comentario</span><p id="par0025" class="elsevierStylePara elsevierViewall">El HHT fue descrito por Santa Cruz y Aronberg en 1988&#46; Es una lesi&#243;n vascular benigna que aparece en el tronco y las piernas de pacientes de edad media &#40;30-40 a&#241;os&#41;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">1</span></a>&#46; Aunque el origen de esta lesi&#243;n todav&#237;a es desconocido&#44; se han publicado art&#237;culos que sugieren que es debido a un traumatismo de un hemangioma preexistente<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">2</span></a>&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">La presencia de receptores hormonales de estr&#243;genos&#44; observada mediante inmunohistoqu&#237;mica&#44; sugiere que los estr&#243;genos podr&#237;an acelerar la proliferaci&#243;n y dilataci&#243;n endotelial y&#44; por tanto&#44; justificar el comportamiento cl&#237;nico que presenta esta lesi&#243;n<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">3</span></a>&#46; Por otra parte&#44; la positividad para D2-40 y la negatividad de la inmunotinci&#243;n de CD34 de las c&#233;lulas endoteliales&#44; as&#237; como la ausencia del marcador de actina en los pericitos&#44; orienta hacia el posible origen linf&#225;tico de la lesi&#243;n<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">4</span></a>&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Cl&#237;nicamente&#44; el HHT suele presentarse como una p&#225;pula rojo-viol&#225;cea&#44; rodeada de un halo perif&#233;rico de aspecto purp&#250;rico&#44; equim&#243;tico&#46; Puede o no acompa&#241;arse de s&#237;ntomas como picor o dolor&#46; Aunque lo m&#225;s frecuente es la presencia de una lesi&#243;n solitaria&#44; se ha descrito la presencia de m&#250;ltiples lesiones simult&#225;neas en un mismo paciente&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">El HHT muestra un patr&#243;n dermatosc&#243;pico muy caracter&#237;stico&#44; como se ha descrito en la <a class="elsevierStyleCrossRef" href="#fig0010">figura 2</a>&#46; Seg&#250;n el estudio de la serie m&#225;s larga hasta la fecha descrita con un total de 35 casos<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">5</span></a>&#44; la dermatoscopia muestra en el 71&#44;4&#37; lagunas rojas y oscuras centrales y un &#225;rea homog&#233;nea circular perif&#233;rica rojiza-viol&#225;cea&#46; En nuestro paciente&#44; se muestra claramente el halo perif&#233;rico bif&#225;sico que define el aspecto en diana que caracteriza a esta lesi&#243;n&#46; El diagn&#243;stico diferencial incluye lesiones pigmentadas malignas como el melanoma<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">6</span></a>&#44; dermatofibroma&#44; sarcoma de Kaposi&#44; picaduras de insecto o el carcinoma basocelular<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">7</span></a>&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">El HHT es una lesi&#243;n vascular benigna cuyo patr&#243;n dermatosc&#243;pico caracter&#237;stico permite diferenciarlo de otras lesiones&#46; Cuando se presenta sin halo equim&#243;tico&#44; si existen dudas diagn&#243;sticas&#44; la extirpaci&#243;n quir&#250;rgica y su estudio histopatol&#243;gico son la actitud m&#225;s correcta&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conflicto de intereses</span><p id="par0050" class="elsevierStylePara elsevierViewall">Los autores declaran no tener ning&#250;n conflicto de intereses&#46;</p></span></span>"
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