Imágenes en Dermatología
Pterigión dorsal y onicólisis asociados a un penfigoide ampolloso
Dorsal Pterygium and Onycholysis Associated With Bullous Pemphigoid
H. Iznardo
, C. García-Melendo, J.F. Mir-Bonafé
Corresponding author
Servicio de Dermatología, Hospital de la Sant Creu i Sant Pau, Barcelona, España
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Iznardo, C. García-Melendo, J.F. Mir-Bonafé" "autores" => array:3 [ 0 => array:4 [ "nombre" => "H." "apellidos" => "Iznardo" "email" => array:1 [ 0 => "heizruiz@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "C." "apellidos" => "García-Melendo" ] 2 => array:2 [ "nombre" => "J.F." "apellidos" => "Mir-Bonafé" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Hospital de la Sant Creu i Sant Pau, Barcelona, España" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Autor para correspondencia." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Dorsal Pterygium and Onycholysis Associated With Bullous Pemphigoid" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1097 "Ancho" => 1625 "Tamanyo" => 217789 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Una mujer de 68 años con historia de penfigoide ampolloso (PA) de más de 10 años de evolución, en tratamiento con prednisona 5<span class="elsevierStyleHsp" style=""></span>mg/día, mostró desde 2014, coincidiendo con un brote importante de su enfermedad, una afectación ungueal en las manos con onicólisis e hiperqueratosis subungueal, sin presentar afectación en pies. Tras repetidos cultivos micológicos negativos, se asoció dicha afectación con su enfermedad de base. En la actualidad, la clínica ungueal persiste pese al buen control del PA, presentando onicólisis de varias uñas, así como una notable estriación longitudinal y un pterigión dorsal. (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">La afectación ungueal en el PA es poco frecuente, aunque en los últimos años se ha descrito una mayor incidencia. Se postula que en su etiopatogenia intervendrían los antígenos anti-PA expresados en la matriz ungueal, el pliegue ungueal proximal, el lecho ungueal y el hiponiquio; además de la formación de ampollas periungueales. Las manifestaciones ungueales observadas hasta la fecha son onicomadesis, paroniquia, onicólisis y la pérdida definitiva de toda la uña; habiéndose descrito el pterigión dorsal en el penfigoide cicatricial.</p><p id="par0015" class="elsevierStylePara elsevierViewall">El pterigión aparece como consecuencia de la afectación de la matriz ungueal, con la formación de un tejido cicatricial. Son causas frecuentes los traumatismos, y también diversos procesos inflamatorios tales como el liquen plano y la enfermedad injerto contra huésped. Su asociación con el PA es excepcional.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2018-07-25" "fechaAceptado" => "2018-09-03" "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1097 "Ancho" => 1625 "Tamanyo" => 217789 ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00017310/0000011100000009/v1_202011260611/S0001731020302246/v1_202011260611/es/main.assets" "Apartado" => array:4 [ "identificador" => "41021" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes en Dermatología" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/0000011100000009/v1_202011260611/S0001731020302246/v1_202011260611/es/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020302246?idApp=UINPBA000044" ]
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