array:23 [
  "pii" => "S1578219008703299"
  "issn" => "15782190"
  "doi" => "10.1016/S1578-2190(08)70329-9"
  "estado" => "S300"
  "fechaPublicacion" => "2008-10-01"
  "aid" => "70329"
  "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
  "copyrightAnyo" => "2008"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Actas Dermosifiliogr. 2008;99:621-7"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 4041
    "formatos" => array:3 [
      "EPUB" => 56
      "HTML" => 1602
      "PDF" => 2383
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1578219008703305"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(08)70330-5"
    "estado" => "S300"
    "fechaPublicacion" => "2008-10-01"
    "aid" => "70330"
    "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L."
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2008;99:628-38"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2120
      "formatos" => array:3 [
        "EPUB" => 52
        "HTML" => 1152
        "PDF" => 916
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>"
      "titulo" => "Prevalence of Atopic Dermatitis in Schoolchildren in Granada&#44; Spain"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "628"
          "paginaFinal" => "638"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Prevalencia de Dermatitis At&#243;pica en Escolares de Granada"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "M&#46;V&#46; Guiote-Dom&#237;nguez, A&#46; Mu&#241;oz-Hoyos, M&#46;T&#46; Guti&#233;rrez-Salmer&#243;n"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "M&#46;V&#46;"
              "apellidos" => "Guiote-Dom&#237;nguez"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Mu&#241;oz-Hoyos"
            ]
            2 => array:2 [
              "nombre" => "M&#46;T&#46;"
              "apellidos" => "Guti&#233;rrez-Salmer&#243;n"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703305?idApp=UINPBA000044"
    "url" => "/15782190/0000009900000008/v1_201304241439/S1578219008703305/v1_201304241439/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1578219008703287"
    "issn" => "15782190"
    "doi" => "10.1016/S1578-2190(08)70328-7"
    "estado" => "S300"
    "fechaPublicacion" => "2008-10-01"
    "aid" => "70328"
    "copyright" => "Academia Espa&#241;ola de Dermatolog&#237;a y Venereolog&#237;a and Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2008;99:608-20"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2786
      "formatos" => array:3 [
        "EPUB" => 46
        "HTML" => 1526
        "PDF" => 1214
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Advances in dermatology</span>"
      "titulo" => "Genotypic Analysis in Primary Cutaneous Lymphomas Using the Standardized Biomed-2 Polymerase Chain Reaction Protocols"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "608"
          "paginaFinal" => "620"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Aplicaci&#243;n de los Protocolos de PCR Biomed-2 en el An&#225;lisis Genot&#237;pico de los Linfomas Cut&#225;neos Primarios"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "F&#46; Gallardo, B&#46; Bellosillo, S&#46; Serrano, R&#46;M&#46; Pujol"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "F&#46;"
              "apellidos" => "Gallardo"
            ]
            1 => array:2 [
              "nombre" => "B&#46;"
              "apellidos" => "Bellosillo"
            ]
            2 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Serrano"
            ]
            3 => array:2 [
              "nombre" => "R&#46;M&#46;"
              "apellidos" => "Pujol"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703287?idApp=UINPBA000044"
    "url" => "/15782190/0000009900000008/v1_201304241439/S1578219008703287/v1_201304241439/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original articles</span>"
    "titulo" => "Diagnostic Utility of Nail Biopsy&#58; A Study of 15 Cases"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "621"
        "paginaFinal" => "627"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "M&#46;V&#46; Barrera-Vigo, A&#46; Tejera-Vaquerizo, M&#46; Mendiola-Fern&#225;ndez, J&#46; Cid, B&#46; Cabra-de Luna, E&#46; Herrera-Ceballos"
        "autores" => array:6 [
          0 => array:4 [
            "nombre" => "M&#46;V&#46;"
            "apellidos" => "Barrera-Vigo"
            "email" => array:1 [
              0 => "mvbvigo&#64;yahoo&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Tejera-Vaquerizo"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Mendiola-Fern&#225;ndez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Cid"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "B&#46;"
            "apellidos" => "Cabra-de Luna"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "E&#46;"
            "apellidos" => "Herrera-Ceballos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Cl&#237;nico Universitario Virgen de la Victoria&#44; M&#225;laga&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Anatom&#237;a Patol&#243;gica&#46; Hospital Cl&#237;nico Universitario Virgen de la Victoria&#44; M&#225;laga&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondence&#58; Servicio de Dermatolog&#237;a&#44; Hospital Universitario Virgen de la Victoria&#44; Campus Universitario Teatinos&#44; 29010 M&#225;laga&#44; Spain&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "La Biopsia Ungueal&#58; un M&#233;todo Diagn&#243;stico de Gran Utilidad&#46; Estudio de 15 casos"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaAceptado" => "2008-01-25"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec84267"
          "palabras" => array:4 [
            0 => "nail biopsy"
            1 => "nail diseases"
            2 => "onychomycosis"
            3 => "nail psoriasis"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec84268"
          "palabras" => array:4 [
            0 => "biopsia ungueal"
            1 => "enfermedades ungueales"
            2 => "onicomicosis"
            3 => "psoriasis ungueal"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">Nail biopsy is thought to be a useful technique for the diagnosis of diseases affecting the nail apparatus and may help avoid delays in the diagnosis of important mucocutaneous diseases&#46; Furthermore&#44; it has therapeutic value in its own right&#46; It is not a difficult technique to perform but it requires an in-depth knowledge of the anatomy and physiology of the nail unit&#44; as well as surgical experience and patient collaboration&#46; In order to assess the diagnostic utility of this technique&#44; we reviewed the nail biopsies performed in our department between June 2005 and May 2006&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We identified 15 patients in whom nail biopsy had been performed&#46; The clinical findings&#44; type of biopsy performed&#44; and histopathologic diagnosis were assessed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Nail biopsy allowed diagnosis of a variety of skin disease in 13 out of 15 patients &#40;psoriasis in 5&#44; onychomycosis in 4&#44; melanonychia in 2&#44; melanoma in 1&#44; and subungual hematoma in 1&#41;&#46; None of the patients presented sequelae as a result of the intervention after several months of follow-up&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">Nail biopsy is a useful tool in cases in which the patient history&#44; clinical presentation&#44; and additional tests have not led to a definitive diagnosis&#46; In our experience&#44; it can be performed safely and with minimal scarring&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">La biopsia ungueal se considera una t&#233;cnica &#250;til en el diagn&#243;stico de los procesos patol&#243;gicos que afectan al sistema ungueal y que permite evitar el retraso en el diagn&#243;stico de procesos cut&#225;neo-mucosos y anexiales importantes&#46; Adem&#225;s&#44; tiene por s&#237; misma un valor terap&#233;utico&#46; No es una t&#233;cnica dif&#237;cil de realizar&#44; pero requiere un completo conocimiento de la anatom&#237;a y la fisiolog&#237;a ungueal&#44; as&#237; como de experiencia quir&#250;rgica y colaboraci&#243;n del paciente&#46; Con el objetivo de evaluar la utilidad diagn&#243;stica de esta t&#233;cnica hemos revisado las biopsias ungueales realizadas en nuestro servicio desde junio de 2005 hasta mayo de 2006&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a 15 pacientes a los que se les realiz&#243; una biopsia ungueal&#46; Se valoraron los aspectos cl&#237;nicos de la patolog&#237;a&#44; el tipo de biopsia realizada y el diagn&#243;stico histopatol&#243;gico&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La biopsia ungueal permiti&#243; un diagn&#243;stico de diversas patolog&#237;as cut&#225;neas en 13 de los 15 pacientes &#40;5 psoriasis&#44; 4 onicomicosis&#44; 2 melanoniquias longitudinales&#44; 1 melanoma y 1 hematoma subungueal&#41;&#46; Ninguno de los pacientes present&#243; secuelas de la intervenci&#243;n tras varios meses de seguimiento&#46;</p> <span class="elsevierStyleSectionTitle">Conclusi&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">La biopsia ungueal es una herramienta &#250;til en aquellos procesos en los que por la historia&#44; la cl&#237;nica y los estudios complementarios no se haya podido establecer un diagn&#243;stico exacto&#46; Seg&#250;n nuestra experiencia puede ser realizada de forma segura y con un m&#237;nimo da&#241;o cicatricial&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:8 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patolog&#237;a ungueal"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46; Ribera"
                            1 => "J&#46;M&#46; Casanova"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "FMC"
                        "fecha" => "2000"
                        "volumen" => "07"
                        "paginaInicial" => "362"
                        "paginaFinal" => "377"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagn&#243;stico en patolog&#237;a ungueal&#46; Capilaroscopia&#46; Otras t&#233;cnicas de exploraci&#243;n en onicolog&#237;a&#46; Selecci&#243;n del paciente para biopsia y cirug&#237;a ungueal"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; S&#225;nchez"
                            1 => "F&#46; Camacho"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Monogr Dermatol"
                        "fecha" => "1991"
                        "volumen" => "5"
                        "paginaInicial" => "281"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nail biopsy&#46; Indications and methods"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Rich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Dermatol Surg Oncol"
                        "fecha" => "1992"
                        "volumen" => "18"
                        "paginaInicial" => "673"
                        "paginaFinal" => "682"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1307222"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nail biopsy&#58; indications and methods"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Rich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2001"
                        "volumen" => "27"
                        "paginaInicial" => "229"
                        "paginaFinal" => "234"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11277887"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Longitudinal nail biopsy&#58; utility in 20-nail dystrophy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Grover"
                            1 => "S&#46; Khandpur"
                            2 => "B&#46; Reddy"
                            3 => "K&#46; Chaturvedi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2003"
                        "volumen" => "29"
                        "paginaInicial" => "1125"
                        "paginaFinal" => "1129"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14641339"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cirug&#237;a dermatol&#243;gica de la regi&#243;n ungueal"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "E&#46; Haneke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Monogr Dermatol"
                        "fecha" => "1991"
                        "volumen" => "6"
                        "paginaInicial" => "408"
                        "paginaFinal" => "411"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nail biopsy&#58; assessment of indications and outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Grover"
                            1 => "S&#46; Nanda"
                            2 => "B&#46; Reddy"
                            3 => "K&#46; Chaturvedi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg"
                        "fecha" => "2005"
                        "volumen" => "31"
                        "paginaInicial" => "190"
                        "paginaFinal" => "194"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15762213"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46; Grover"
                            1 => "B&#46; Reddy"
                            2 => "K&#46; Chaturvedi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1365-2133.2005.06862.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Dermatol"
                        "fecha" => "2005"
                        "volumen" => "153"
                        "paginaInicial" => "1153"
                        "paginaFinal" => "1158"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16307651"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000009900000008/v1_201304241439/S1578219008703299/v1_201304241439/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6155"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original Articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009900000008/v1_201304241439/S1578219008703299/v1_201304241439/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703299?idApp=UINPBA000044"
]
Share
Journal Information
Vol. 99. Issue 8.
Pages 621-627 (October 2008)
Share
Share
Download PDF
More article options
Vol. 99. Issue 8.
Pages 621-627 (October 2008)
Original articles
Full text access
Diagnostic Utility of Nail Biopsy: A Study of 15 Cases
La Biopsia Ungueal: un Método Diagnóstico de Gran Utilidad. Estudio de 15 casos
Visits
8374
M.V. Barrera-Vigoa,
Corresponding author
mvbvigo@yahoo.es

Correspondence: Servicio de Dermatología, Hospital Universitario Virgen de la Victoria, Campus Universitario Teatinos, 29010 Málaga, Spain.
, A. Tejera-Vaquerizoa, M. Mendiola-Fernándeza, J. Cidb, B. Cabra-de Lunab, E. Herrera-Ceballosa
a Servicio de Dermatología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain
b Servicio de Anatomía Patológica. Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics
Abstract
Introduction

Nail biopsy is thought to be a useful technique for the diagnosis of diseases affecting the nail apparatus and may help avoid delays in the diagnosis of important mucocutaneous diseases. Furthermore, it has therapeutic value in its own right. It is not a difficult technique to perform but it requires an in-depth knowledge of the anatomy and physiology of the nail unit, as well as surgical experience and patient collaboration. In order to assess the diagnostic utility of this technique, we reviewed the nail biopsies performed in our department between June 2005 and May 2006.

Patients and methods

We identified 15 patients in whom nail biopsy had been performed. The clinical findings, type of biopsy performed, and histopathologic diagnosis were assessed.

Results

Nail biopsy allowed diagnosis of a variety of skin disease in 13 out of 15 patients (psoriasis in 5, onychomycosis in 4, melanonychia in 2, melanoma in 1, and subungual hematoma in 1). None of the patients presented sequelae as a result of the intervention after several months of follow-up.

Conclusion

Nail biopsy is a useful tool in cases in which the patient history, clinical presentation, and additional tests have not led to a definitive diagnosis. In our experience, it can be performed safely and with minimal scarring.

Key words:
nail biopsy
nail diseases
onychomycosis
nail psoriasis
Resumen
Introducción

La biopsia ungueal se considera una técnica útil en el diagnóstico de los procesos patológicos que afectan al sistema ungueal y que permite evitar el retraso en el diagnóstico de procesos cutáneo-mucosos y anexiales importantes. Además, tiene por sí misma un valor terapéutico. No es una técnica difícil de realizar, pero requiere un completo conocimiento de la anatomía y la fisiología ungueal, así como de experiencia quirúrgica y colaboración del paciente. Con el objetivo de evaluar la utilidad diagnóstica de esta técnica hemos revisado las biopsias ungueales realizadas en nuestro servicio desde junio de 2005 hasta mayo de 2006.

Pacientes y métodos

Se incluyó a 15 pacientes a los que se les realizó una biopsia ungueal. Se valoraron los aspectos clínicos de la patología, el tipo de biopsia realizada y el diagnóstico histopatológico.

Resultados

La biopsia ungueal permitió un diagnóstico de diversas patologías cutáneas en 13 de los 15 pacientes (5 psoriasis, 4 onicomicosis, 2 melanoniquias longitudinales, 1 melanoma y 1 hematoma subungueal). Ninguno de los pacientes presentó secuelas de la intervención tras varios meses de seguimiento.

Conclusión

La biopsia ungueal es una herramienta útil en aquellos procesos en los que por la historia, la clínica y los estudios complementarios no se haya podido establecer un diagnóstico exacto. Según nuestra experiencia puede ser realizada de forma segura y con un mínimo daño cicatricial.

Palabras clave:
biopsia ungueal
enfermedades ungueales
onicomicosis
psoriasis ungueal
Full text is only aviable in PDF
References
[1.]
M. Ribera, J.M. Casanova.
Patología ungueal.
FMC, 07 (2000), pp. 362-377
[2.]
P. Sánchez, F. Camacho.
Diagnóstico en patología ungueal. Capilaroscopia. Otras técnicas de exploración en onicología. Selección del paciente para biopsia y cirugía ungueal.
Monogr Dermatol, 5 (1991), pp. 281
[3.]
P. Rich.
Nail biopsy. Indications and methods.
J Dermatol Surg Oncol, 18 (1992), pp. 673-682
[4.]
P. Rich.
Nail biopsy: indications and methods.
Dermatol Surg, 27 (2001), pp. 229-234
[5.]
C. Grover, S. Khandpur, B. Reddy, K. Chaturvedi.
Longitudinal nail biopsy: utility in 20-nail dystrophy.
Dermatol Surg, 29 (2003), pp. 1125-1129
[6.]
E. Haneke.
Cirugía dermatológica de la región ungueal.
Monogr Dermatol, 6 (1991), pp. 408-411
[7.]
C. Grover, S. Nanda, B. Reddy, K. Chaturvedi.
Nail biopsy: assessment of indications and outcome.
Dermatol Surg, 31 (2005), pp. 190-194
[8.]
C. Grover, B. Reddy, K. Chaturvedi.
Br J Dermatol, 153 (2005), pp. 1153-1158
Copyright © 2008. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
Download PDF
Idiomas
Actas Dermo-Sifiliográficas
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?