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        "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p class="elsevierStyleSimplePara elsevierViewall">Photochemotherapy with 8-methoxypsoralen and long-wavelength UV-A &#40;PUVA&#41; has been extensively used for the treatment of various skin diseases since its approval in 1982 by the US Food and Drug Administration&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p class="elsevierStyleSimplePara elsevierViewall">A retrospective study was performed of patients treated with PUVA&#44; including topical and systemic treatment&#44; over a period of 14 years&#46; All patients were treated using a standard PUVA therapy regimen&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 877 patients were analyzed for the period 1982 to 1996&#46; Forty-one skin diseases were treated&#44; including 341 cases of psoriasis and 71 cutaneous T-cell lymphomas&#46; The aim of the study was to describe the characteristics of the patients treated with PUVA therapy during that period and compare the results with those observed in other regions&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Although PUVA therapy is widely used in a large number of countries for the treatment of various skin diseases&#44; few studies have described the characteristics of the patients and the differences in the parameters of PUVA according to the disease&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">La fotoquimioterapia con 8-metoxipsoraleno y radiaci&#243;n ultravioleta de longitud de onda larga A &#40;PUVA&#41; es frecuentemente utilizada para el tratamiento de diferentes enfermedades cut&#225;neas desde que en 1982&#44; la <span class="elsevierStyleItalic">Food and Drug Administration</span> aprobase su uso&#46;</p> <span class="elsevierStyleSectionTitle">M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">En este estudio retrospectivo se han analizado los pacientes tratados con PUVA&#44; incluyendo tratamiento t&#243;pico y sist&#233;mico durante 14 a&#241;os&#46; Todos estos pacientes recibieron un r&#233;gimen de terapia PUVA est&#225;ndar&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Durante el per&#237;odo de 1982 a 1996 se analizaron 877 pacientes&#46; Un total de 41 dermatosis recibieron el tratamiento entre las que destacamos 341 casos de psoriasis y 71 casos de linfomas cut&#225;neos de c&#233;lulas T&#46; El trabajo tiene como finalidad describir las caracter&#237;sticas de los pacientes tratados con terapia PUVA durante estos a&#241;os y comparar los resultados con los procedentes de otros &#225;mbitos&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque la terapia PUVA est&#225; ampliamente distribuida en un gran n&#250;mero de pa&#237;ses para el tratamiento de diferentes enfermedades cut&#225;neas&#44; existen pocos estudios que indiquen las caracter&#237;sticas de estos pacientes y las variaciones en los par&#225;metros de PUVA dependiendo de las diferentes enfermedades&#46;</p>"
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noviembre 2007 Use of Psoralen Plus UV-A Therapy in the Autonomous Community of Valencia, Spain
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Vol. 98. Núm. 9.
Páginas 611-616 (noviembre 2007)
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Vol. 98. Núm. 9.
Páginas 611-616 (noviembre 2007)
Original articles
DOI: 10.1016/S1578-2190(07)70526-7
Acceso a texto completo
Use of Psoralen Plus UV-A Therapy in the Autonomous Community of Valencia, Spain
Estudio Epidemiológico de la Puvaterapia en la Comunidad Valenciana
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C. Grau-Salvata,
Autor para correspondencia
Fcmc@tinet.org

Correspondence: Rambla Nova, 118, 6°, 1°. 43001 Tarragona. Spain.
, J.J. Vilata-Corellb, A. Azón-Massolivera, A. Pérez-Ferriolsb
a Servicio de Dermatología, Hospital Sant Joan, Reus, Tarragona, Spain
b Servicio de Dermatología, Hospital General Universitario de Valencia, Spain
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Abstract
Background

Photochemotherapy with 8-methoxypsoralen and long-wavelength UV-A (PUVA) has been extensively used for the treatment of various skin diseases since its approval in 1982 by the US Food and Drug Administration.

Methods

A retrospective study was performed of patients treated with PUVA, including topical and systemic treatment, over a period of 14 years. All patients were treated using a standard PUVA therapy regimen.

Results

A total of 877 patients were analyzed for the period 1982 to 1996. Forty-one skin diseases were treated, including 341 cases of psoriasis and 71 cutaneous T-cell lymphomas. The aim of the study was to describe the characteristics of the patients treated with PUVA therapy during that period and compare the results with those observed in other regions.

Conclusions

Although PUVA therapy is widely used in a large number of countries for the treatment of various skin diseases, few studies have described the characteristics of the patients and the differences in the parameters of PUVA according to the disease.

Key words:
psoralen psoralen UV-A therapy
psoriasis
epidemiology
Resumen
Introducción

La fotoquimioterapia con 8-metoxipsoraleno y radiación ultravioleta de longitud de onda larga A (PUVA) es frecuentemente utilizada para el tratamiento de diferentes enfermedades cutáneas desde que en 1982, la Food and Drug Administration aprobase su uso.

Métodos

En este estudio retrospectivo se han analizado los pacientes tratados con PUVA, incluyendo tratamiento tópico y sistémico durante 14 años. Todos estos pacientes recibieron un régimen de terapia PUVA estándar.

Resultados

Durante el período de 1982 a 1996 se analizaron 877 pacientes. Un total de 41 dermatosis recibieron el tratamiento entre las que destacamos 341 casos de psoriasis y 71 casos de linfomas cutáneos de células T. El trabajo tiene como finalidad describir las características de los pacientes tratados con terapia PUVA durante estos años y comparar los resultados con los procedentes de otros ámbitos.

Conclusiones

Aunque la terapia PUVA está ampliamente distribuida en un gran número de países para el tratamiento de diferentes enfermedades cutáneas, existen pocos estudios que indiquen las características de estos pacientes y las variaciones en los parámetros de PUVA dependiendo de las diferentes enfermedades.

Palabras clave:
puvaterapia
psoriasis
epidemiología
El Texto completo está disponible en PDF
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Copyright © 2007. Academia Española de Dermatología y Venereología and Elsevier España, S.L.

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