Información del artículo
Abstract
Numerous therapeutic options are now available for the treatment of basal cell carcinoma. However, few randomized controlled trials with 5-year follow-up have compared the effectiveness of the different treatments. Such a comparison is difficult, probably because efficacy depends on several factors: those related to the tumor, the patient, the technique, and the dermatologist's experience. We first describe the available therapeutic options, including certain innovative treatments. We have divided them into 2 main groups—surgical and nonsurgical—and focus on the indications, advantages, and disadvantages of each one, as well as on the cure and recurrence rates. Then, based on the evidence reviewed, we attempt to provide an outline of the therapeutic strategies recommended in basal cell carcinoma, and the approach to be used in specific situations. We also describe our own experience.
Keywords:
Carcinoma
Basal cell
Skin cancer
Treatment
Surgery
Resumen
El arsenal terapéutico para el tratamiento de los carcinomas basocelulares hoy en día es muy amplio. No obstante, existen pocos estudios controlados, aleatorizados con seguimiento a 5 años que comparen la eficacia de los diferentes tratamientos. Esto es difícil, debido probablemente a que la eficacia de los mismos depende de varios factores: los derivados del propio tumor, del paciente, de la técnica y del manejo de ella hecho por el dermatólogo. Describiremos en primer lugar las opciones terapéuticas con las que contamos, incluyendo además algunos tratamientos innovadores, dividiéndolas en dos grupos principales: quirúrgicos y no quirúrgicos, enfatizando en las indicaciones, ventajas y desventajas de cada tipo, así como las tasas de curación y recurrencia de los mismos. Posteriormente con las evidencias presentadas intentaremos, de manera esquemática, exponer las estrategias terapéuticas recomendadas en cada caso, las actitudes a adoptar en determinadas situaciones así como nuestra propia experiencia.
Palabras clave:
Carcinoma
Basocelular
Cáncer de piel
Tratamiento
Cirugía
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