Psoriasis pustulosa, psoriasis palmoplantar, psoriasis eritrodérmica y etanercept

López-Estebaranz, J.L.; Ruiz-Genao, D.

doi:10.1016/S0001-7310(10)70006-5

Información del artículo

Resumen

Etanercept está aprobado para el tratamiento de la psoriasis en placas moderada-grave; esta es la forma más frecuente de psoriasis (80%). En otras formas de psoriasis el uso de etanercept, al igual que el de otras terapias biológicas, se ha publicado de forma aislada con resultados satisfactorios. Presentamos el caso de una paciente con psoriasis palmoplantar pustulosa refractaria a múltiples tratamientos (corticoides tópicos, fototerapia, metotrexato) que respondió favorablemente al uso de etanercept a dosis de 50 mg dos veces por semana. La paciente ha mantenido una remisión total de las lesiones tras 6 meses de finalizar el tratamiento.

Revisamos los casos publicados de psoriasis palmoplantar tratados con etanercept y también el uso de este fármaco en otras formas de psoriasis pustulosa y de psoriasis eritrodérmica.

Palabras clave:

Psoriasis pustulosa generalizada de Von Zumbusch

Psoriasis palmoplantar

Acropustulosis continua de Hallopeau

Psoriasis eritrodérmica

Etanercept

Abstract

Etanercept has been approved for the treatment of moderate-severe plaque psoriasis. This is the most frequent form of psoriasis (80%). In other forms of psoriasis, the use of etanercept, as that of other biological therapies, has been published in an isolated way with satisfactory results. We present a patient with palmoplantar pustulous psoriasis palmoplantar refractory to multiple treatments (topical corticosteroids, phototherapy, methotrexate) who responded favorably to the use of 50 mg biweekly doses of etanercept. The patient has maintained total remission of the lesions 6 months after having terminated treatment.

We review the cases published on palmoplantar psoriasis treated with etanercept and also the use of this drug in other forms of pustular psoriasis and of erythrodermal psoriasis.

Keywords:

Generalized pustular psoriasis-Von Zumbusch

Palmoplantar psoriasis

Hallopeau acropustulosis perstan

Erythrodermal psoriasis

Etanercept

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