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Vol. 100. Núm. 9.
Páginas 808-812 (noviembre 2009)
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Vol. 100. Núm. 9.
Páginas 808-812 (noviembre 2009)
Case report
Acceso a texto completo
Presentation of 2 New Cases of Cutaneous Angiomyolipomas and Literature Review
Angiomiolipomas Cutáneos: Aportación de dos Casos y Revisión de la Literatura
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6620
J. Sánchez-Estellaa,
Autor para correspondencia
jsancheze@meditex.es

Correspondence: Plaza de Alemania 3, 3.° 1.a Pta, 49014 Zamora, Spain.
, M.T. Bordel-Gómeza, T. Zamora-Martínezb
a Servicio de Dermatología, Hospital Virgen de la Concha, Zamora, Spain
b Servicio de Anatomía Patológica, Hospital Virgen de la Concha, Zamora, Spain
Este artículo ha recibido
Información del artículo
Abstract

We present 2 new cases of cutaneous angiomyolipomas with very similar characteristics, located in the postauricular region of 2 women aged 58 and 52 years. The lesions measured 1.5 cm and 1 cm across and had been present for 5 and 2 years, respectively. Both presented a previously unreported clinical sign: change in size according to the ambient temperature. They had well defined borders and a predominance of smooth muscle and vessels, particularly arteries. In contrast to renal angiomyolipomas, which are often associated with tuberous sclerosis, these angiomyolipomas were negative for melanocytic immunohistochemical markers (human melanoma black-45 antigen and melanoma antigen recognized by T cells 1).The clinical characteristics of the 32 cases published until present are reviewed. The relationship of these tumors with angioleiomyomas and renal angiomyolipomas is discussed.

Key words:
cutaneous angiomyolipoma
angiolipoleiomyoma
mucocutaneous angiomyolipoma
Resumen

Presentamos dos nuevos casos de angiomiolipomas cutáneos de características muy similares. Se localizaban en región retroauricular de dos mujeres de 58 y 52 años. Tenían un tamaño de 1,5 y 1 cm de diámetro y una evolución de 5 y 2 años, respectivamente. Ambos presentaban un signo clínico no previamente descrito: cambio de tamaño según la temperatura ambiente. Estaban bien delimitados, el elemento predominante era el músculo liso y los vasos, sobre todo arteriales. A diferencia de lo que sucede con los angiomiolipomas renales frecuentemente asociados a esclerosis tuberosa, fueron negativos para los marcadores inmunohistoquímicos melanocitarios (HMB-45 y MART-1). Se revisan las características clínicas de los 32 casos publicados hasta la actualidad. Se discute la relación de estos tumores con los angioleiomiomas y los angiomiolipomas renales.

Palabras clave:
angiomiolipoma cutáneo
angiolipoleiomioma
angiomiolipoma mucocutáneo
El Texto completo está disponible en PDF
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Copyright © 2009. Academia Española de Dermatología y Venereología and Elsevier España, S.L.
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