array:24 [
  "pii" => "S1578219021002353"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2021.07.023"
  "estado" => "S300"
  "fechaPublicacion" => "2021-10-01"
  "aid" => "2653"
  "copyrightAnyo" => "2021"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "sco"
  "cita" => "Actas Dermosifiliogr. 2021;112:847-8"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S000173102100171X"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2019.09.015"
      "estado" => "S300"
      "fechaPublicacion" => "2021-10-01"
      "aid" => "2653"
      "copyright" => "AEDV"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "sco"
      "cita" => "Actas Dermosifiliogr. 2021;112:847-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Foro de Residentes</span>"
        "titulo" => "Hemangiomas cong&#233;nitos no involutivos &#40;NICH&#41; con crecimiento postnatal"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "847"
            "paginaFinal" => "848"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Noninvoluting Congenital Hemangiomas That Exhibit Postnatal Growth"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "J&#46; Boix-Vilanova, I&#46; Gracia-Darder, A&#46; Mart&#237;n-Santiago"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Boix-Vilanova"
              ]
              1 => array:2 [
                "nombre" => "I&#46;"
                "apellidos" => "Gracia-Darder"
              ]
              2 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Mart&#237;n-Santiago"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219021002353"
          "doi" => "10.1016/j.adengl.2021.07.023"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002353?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S000173102100171X?idApp=UINPBA000044"
      "url" => "/00017310/0000011200000009/v1_202110020514/S000173102100171X/v1_202110020514/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219021002390"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.07.027"
    "estado" => "S300"
    "fechaPublicacion" => "2021-10-01"
    "aid" => "2660"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2021;112:849-50"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Resident&#39;s Forum</span>"
      "titulo" => "RF - Mohs Micrographic Surgery&#58; Same-Day or Delayed Reconstruction&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "849"
          "paginaFinal" => "850"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "FR - Cirug&#237;a microgr&#225;fica de Mohs&#46; &#191;Cierre inmediato o cierre diferido&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "T&#46; Montero-Vilchez, A&#46; Rodriguez-Tejero, J&#46; Tercedor-Sanchez"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Montero-Vilchez"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Rodriguez-Tejero"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Tercedor-Sanchez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731021001782"
        "doi" => "10.1016/j.ad.2019.09.016"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021001782?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002390?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002390/v1_202110091021/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S157821902100233X"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.07.021"
    "estado" => "S300"
    "fechaPublicacion" => "2021-10-01"
    "aid" => "2608"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2021;112:845-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>"
      "titulo" => "Noonan Syndrome With Multiple Lentigines&#58; Subtle Key Skin Clues to the Diagnosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "845"
          "paginaFinal" => "846"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "S&#237;ndrome de Noonan con lentiginosis&#58; manifestaciones dermatol&#243;gicas sutiles y claves"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1633
              "Ancho" => 2175
              "Tamanyo" => 491944
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image showing multiple lentigines&#44; keratosis pilaris&#44; sparse eyebrows&#44; a broad nasal philtrum&#44; bulbous nose&#44; and curly hair&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "B&#46; Lozano-Masdemont, J&#46; Rojas-Calva, M&#46;T&#46; Darnaude-Ortiz"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "B&#46;"
              "apellidos" => "Lozano-Masdemont"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Rojas-Calva"
            ]
            2 => array:2 [
              "nombre" => "M&#46;T&#46;"
              "apellidos" => "Darnaude-Ortiz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731021001034"
        "doi" => "10.1016/j.ad.2019.07.024"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021001034?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821902100233X?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000009/v1_202110091021/S157821902100233X/v1_202110091021/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Resident&#8217;s Forum</span>"
    "titulo" => "Noninvoluting Congenital Hemangiomas That Exhibit Postnatal Growth"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "847"
        "paginaFinal" => "848"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "J&#46; Boix-Vilanova, I&#46; Gracia-Darder, A&#46; Mart&#237;n-Santiago"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "J&#46;"
            "apellidos" => "Boix-Vilanova"
            "email" => array:1 [
              0 => "julian.boix@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "I&#46;"
            "apellidos" => "Gracia-Darder"
          ]
          2 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Mart&#237;n-Santiago"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a del Hospital Universitario Son Espases&#44; Palma de Mallorca &#40;Islas Baleares&#41;&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Hemangiomas cong&#233;nitos no involutivos &#40;NICH&#41; con crecimiento postnatal"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Congenital hemangioma &#40;CH&#41; is a type of vascular tumor that develops in the uterus and is therefore fully formed at birth&#46; CH differs from infantile hemangioma &#40;IH&#41; both clinically and histologically&#46; Immunohistochemistry for the marker Glut-1 &#40;glucose transporter-1&#41; is characteristically positive in IH and negative in CH&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">CH can be divided into three subgroups based on tumor course&#58; rapidly involuting CH &#40;RICH&#41;&#59; non-involuting CH &#40;NICH&#41;&#59; and partially involutional CH &#40;PICH&#41;&#46; RICH is characterized by regression between 6 and 14 months&#44; sometimes without leaving a residual lesion&#44; and in other cases leaving progressive underlying lipoatrophy after rapid involution&#46; NICH does not involute&#46; PICH initially behaves like RICH but involution stops at a certain point&#44; leaving a lesion indistinguishable from NICH&#46; There is marked clinical overlap between the different forms of CH&#46; PICH was described later than RICH and NICH&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and therefore it is highly likely that some cases of NICH described in the literature actually correspond to PICH&#46; Distinction between PICH and NICH is difficult in the absence of images acquired during the first days of life&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">NICH is slightly more common in girls and more frequently appears on the trunk and extremities&#46; This is a vascular-like lesion of which two clinical variants have been described&#58; a macule with a slightly atrophic surface that may exhibit mild induration or turgor on palpation&#59; and a nodular or plaque-like lesion&#46; In both cases a slight increase in temperature can be perceived upon palpation and Doppler ultrasound reveals an increase in flow&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Two recent publications described possible atypical postnatal growth of NICH&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a> Until recently there were only isolated reports of this type of hemangioma&#46; However&#44; Cossio et al<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> reported a series of 80 NICH&#44; of which 9 &#40;11&#46;2&#37;&#41; exhibited growth after a period of stability of 2&#8211;10 years &#40;mean&#44; 5&#46;3 years&#41;&#46; Furthermore&#44; the authors reported the appearance of telangiectasias&#44; reddish&#44; occasionally bleeding papules&#44; and pyogenic granulomas on these tumors&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">It has been suggested that persistent high flows in the vessels of these lesions may account for late growth&#44; and that this could be much more frequent than reported&#44; since in many cases CH is operated on before adolescence&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a> In both NICH and RICH somatic mutations have been described in codon 209 &#40;Gln209&#41; in GNAQ and GNA11&#44; suggesting that their course is determined by other genetic&#44; epigenetic&#44; or environmental factors&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">In conclusion&#44; CH is a group of rare vascular tumors that share a series of genetic and clinical characteristics but differ in their course&#44; which is influenced by factors that remain to be identified&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1427058"
          "palabras" => array:3 [
            0 => "Hemangioma"
            1 => "Pediatric dermatology"
            2 => "Vascular anomaly"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Boix-Vilanova J&#44; Gracia-Darder I&#44; Mart&#237;n-Santiago A&#46; Hemangiomas cong&#233;nitos no involutivos &#40;NICH&#41; con crecimiento postnatal&#46; Actas Dermosifiliogr&#46; 2021&#59;112&#58;847&#8211;848&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics of noninvoluting congenital hemangioma&#58; a retrospective review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;W&#46; Lee"
                            1 => "I&#46;J&#46; Frieden"
                            2 => "J&#46;L&#46; Streicher"
                            3 => "T&#46; McCalmont"
                            4 => "A&#46;N&#46; Haggstrom"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2014.01.860"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "70"
                        "paginaInicial" => "899"
                        "paginaFinal" => "903"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24630000"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Partially involuting congenital hemangiomas&#58; a report of 8 cases and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46; Nasseri"
                            1 => "M&#46; Piram"
                            2 => "C&#46;C&#46; McCuaig"
                            3 => "V&#46; Kokta"
                            4 => "J&#46; Dubois"
                            5 => "J&#46; Powell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2013.09.018"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "70"
                        "paginaInicial" => "75"
                        "paginaFinal" => "79"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24176519"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Congenital hemangioma exhibiting postnatal growth"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "N&#46; Kn&#246;pfel"
                            1 => "R&#46; W&#228;lchli"
                            2 => "I&#46; Luchsinger"
                            3 => "M&#46; Theiler"
                            4 => "L&#46; Weibel"
                            5 => "A&#46; Schwieger-Briel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/pde.13813"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "36"
                        "paginaInicial" => "548"
                        "paginaFinal" => "554"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30900306"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Non-involuting congenital hemangiomas &#40;NICH&#41; with postnatal atypical growth&#58; a case series"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;L&#46; Cossio"
                            1 => "J&#46; Dubois"
                            2 => "C&#46;C&#46; McCuaig"
                            3 => "J&#46; Coulombe"
                            4 => "A&#46; Hatami"
                            5 => "D&#46; Marcoux"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/pde.13837"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "36"
                        "paginaInicial" => "466"
                        "paginaFinal" => "470"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31033005"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Somatic activating mutations in GNAQ and GNA11 are associated with congenital hemangioma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "U&#46;M&#46; Ayturk"
                            1 => "J&#46;A&#46; Couto"
                            2 => "S&#46; Hann"
                            3 => "J&#46;B&#46; Mulliken"
                            4 => "K&#46;L&#46; Williams"
                            5 => "A&#46;Y&#46; Huang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ajhg.2016.03.009"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Hum Genet&#46;"
                        "fecha" => "2016"
                        "volumen" => "98"
                        "paginaInicial" => "789"
                        "paginaFinal" => "795"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27058448"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002353/v1_202110091021/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "34945"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Resident&#39;s Forum"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000009/v1_202110091021/S1578219021002353/v1_202110091021/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002353?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Resident’s Forum
Noninvoluting Congenital Hemangiomas That Exhibit Postnatal Growth
Hemangiomas congénitos no involutivos (NICH) con crecimiento postnatal
J. Boix-Vilanova
Autor para correspondencia
julian.boix@gmail.com

Corresponding author.
, I. Gracia-Darder, A. Martín-Santiago
Servicio de Dermatología del Hospital Universitario Son Espases, Palma de Mallorca (Islas Baleares), Spain
Leído
3308
Veces
se ha leído el artículo
1352
Total PDF
1956
Total HTML
Compartir estadísticas
 array:24 [
  "pii" => "S1578219021002353"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2021.07.023"
  "estado" => "S300"
  "fechaPublicacion" => "2021-10-01"
  "aid" => "2653"
  "copyrightAnyo" => "2021"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "sco"
  "cita" => "Actas Dermosifiliogr. 2021;112:847-8"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S000173102100171X"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2019.09.015"
      "estado" => "S300"
      "fechaPublicacion" => "2021-10-01"
      "aid" => "2653"
      "copyright" => "AEDV"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "sco"
      "cita" => "Actas Dermosifiliogr. 2021;112:847-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Foro de Residentes</span>"
        "titulo" => "Hemangiomas cong&#233;nitos no involutivos &#40;NICH&#41; con crecimiento postnatal"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "847"
            "paginaFinal" => "848"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Noninvoluting Congenital Hemangiomas That Exhibit Postnatal Growth"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "J&#46; Boix-Vilanova, I&#46; Gracia-Darder, A&#46; Mart&#237;n-Santiago"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Boix-Vilanova"
              ]
              1 => array:2 [
                "nombre" => "I&#46;"
                "apellidos" => "Gracia-Darder"
              ]
              2 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Mart&#237;n-Santiago"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219021002353"
          "doi" => "10.1016/j.adengl.2021.07.023"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002353?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S000173102100171X?idApp=UINPBA000044"
      "url" => "/00017310/0000011200000009/v1_202110020514/S000173102100171X/v1_202110020514/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219021002390"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.07.027"
    "estado" => "S300"
    "fechaPublicacion" => "2021-10-01"
    "aid" => "2660"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2021;112:849-50"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Resident&#39;s Forum</span>"
      "titulo" => "RF - Mohs Micrographic Surgery&#58; Same-Day or Delayed Reconstruction&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "849"
          "paginaFinal" => "850"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "FR - Cirug&#237;a microgr&#225;fica de Mohs&#46; &#191;Cierre inmediato o cierre diferido&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "T&#46; Montero-Vilchez, A&#46; Rodriguez-Tejero, J&#46; Tercedor-Sanchez"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Montero-Vilchez"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Rodriguez-Tejero"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Tercedor-Sanchez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731021001782"
        "doi" => "10.1016/j.ad.2019.09.016"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021001782?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002390?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002390/v1_202110091021/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S157821902100233X"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.07.021"
    "estado" => "S300"
    "fechaPublicacion" => "2021-10-01"
    "aid" => "2608"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2021;112:845-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>"
      "titulo" => "Noonan Syndrome With Multiple Lentigines&#58; Subtle Key Skin Clues to the Diagnosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "845"
          "paginaFinal" => "846"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "S&#237;ndrome de Noonan con lentiginosis&#58; manifestaciones dermatol&#243;gicas sutiles y claves"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1633
              "Ancho" => 2175
              "Tamanyo" => 491944
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image showing multiple lentigines&#44; keratosis pilaris&#44; sparse eyebrows&#44; a broad nasal philtrum&#44; bulbous nose&#44; and curly hair&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "B&#46; Lozano-Masdemont, J&#46; Rojas-Calva, M&#46;T&#46; Darnaude-Ortiz"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "B&#46;"
              "apellidos" => "Lozano-Masdemont"
            ]
            1 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Rojas-Calva"
            ]
            2 => array:2 [
              "nombre" => "M&#46;T&#46;"
              "apellidos" => "Darnaude-Ortiz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731021001034"
        "doi" => "10.1016/j.ad.2019.07.024"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021001034?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821902100233X?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000009/v1_202110091021/S157821902100233X/v1_202110091021/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Resident&#8217;s Forum</span>"
    "titulo" => "Noninvoluting Congenital Hemangiomas That Exhibit Postnatal Growth"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "847"
        "paginaFinal" => "848"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "J&#46; Boix-Vilanova, I&#46; Gracia-Darder, A&#46; Mart&#237;n-Santiago"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "J&#46;"
            "apellidos" => "Boix-Vilanova"
            "email" => array:1 [
              0 => "julian.boix@gmail.com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "I&#46;"
            "apellidos" => "Gracia-Darder"
          ]
          2 => array:2 [
            "nombre" => "A&#46;"
            "apellidos" => "Mart&#237;n-Santiago"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a del Hospital Universitario Son Espases&#44; Palma de Mallorca &#40;Islas Baleares&#41;&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Hemangiomas cong&#233;nitos no involutivos &#40;NICH&#41; con crecimiento postnatal"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Congenital hemangioma &#40;CH&#41; is a type of vascular tumor that develops in the uterus and is therefore fully formed at birth&#46; CH differs from infantile hemangioma &#40;IH&#41; both clinically and histologically&#46; Immunohistochemistry for the marker Glut-1 &#40;glucose transporter-1&#41; is characteristically positive in IH and negative in CH&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">CH can be divided into three subgroups based on tumor course&#58; rapidly involuting CH &#40;RICH&#41;&#59; non-involuting CH &#40;NICH&#41;&#59; and partially involutional CH &#40;PICH&#41;&#46; RICH is characterized by regression between 6 and 14 months&#44; sometimes without leaving a residual lesion&#44; and in other cases leaving progressive underlying lipoatrophy after rapid involution&#46; NICH does not involute&#46; PICH initially behaves like RICH but involution stops at a certain point&#44; leaving a lesion indistinguishable from NICH&#46; There is marked clinical overlap between the different forms of CH&#46; PICH was described later than RICH and NICH&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and therefore it is highly likely that some cases of NICH described in the literature actually correspond to PICH&#46; Distinction between PICH and NICH is difficult in the absence of images acquired during the first days of life&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">NICH is slightly more common in girls and more frequently appears on the trunk and extremities&#46; This is a vascular-like lesion of which two clinical variants have been described&#58; a macule with a slightly atrophic surface that may exhibit mild induration or turgor on palpation&#59; and a nodular or plaque-like lesion&#46; In both cases a slight increase in temperature can be perceived upon palpation and Doppler ultrasound reveals an increase in flow&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Two recent publications described possible atypical postnatal growth of NICH&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a> Until recently there were only isolated reports of this type of hemangioma&#46; However&#44; Cossio et al<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> reported a series of 80 NICH&#44; of which 9 &#40;11&#46;2&#37;&#41; exhibited growth after a period of stability of 2&#8211;10 years &#40;mean&#44; 5&#46;3 years&#41;&#46; Furthermore&#44; the authors reported the appearance of telangiectasias&#44; reddish&#44; occasionally bleeding papules&#44; and pyogenic granulomas on these tumors&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">It has been suggested that persistent high flows in the vessels of these lesions may account for late growth&#44; and that this could be much more frequent than reported&#44; since in many cases CH is operated on before adolescence&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a> In both NICH and RICH somatic mutations have been described in codon 209 &#40;Gln209&#41; in GNAQ and GNA11&#44; suggesting that their course is determined by other genetic&#44; epigenetic&#44; or environmental factors&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">In conclusion&#44; CH is a group of rare vascular tumors that share a series of genetic and clinical characteristics but differ in their course&#44; which is influenced by factors that remain to be identified&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:1 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1427058"
          "palabras" => array:3 [
            0 => "Hemangioma"
            1 => "Pediatric dermatology"
            2 => "Vascular anomaly"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Boix-Vilanova J&#44; Gracia-Darder I&#44; Mart&#237;n-Santiago A&#46; Hemangiomas cong&#233;nitos no involutivos &#40;NICH&#41; con crecimiento postnatal&#46; Actas Dermosifiliogr&#46; 2021&#59;112&#58;847&#8211;848&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Characteristics of noninvoluting congenital hemangioma&#58; a retrospective review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;W&#46; Lee"
                            1 => "I&#46;J&#46; Frieden"
                            2 => "J&#46;L&#46; Streicher"
                            3 => "T&#46; McCalmont"
                            4 => "A&#46;N&#46; Haggstrom"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2014.01.860"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "70"
                        "paginaInicial" => "899"
                        "paginaFinal" => "903"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24630000"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Partially involuting congenital hemangiomas&#58; a report of 8 cases and review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46; Nasseri"
                            1 => "M&#46; Piram"
                            2 => "C&#46;C&#46; McCuaig"
                            3 => "V&#46; Kokta"
                            4 => "J&#46; Dubois"
                            5 => "J&#46; Powell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2013.09.018"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol&#46;"
                        "fecha" => "2014"
                        "volumen" => "70"
                        "paginaInicial" => "75"
                        "paginaFinal" => "79"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24176519"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Congenital hemangioma exhibiting postnatal growth"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "N&#46; Kn&#246;pfel"
                            1 => "R&#46; W&#228;lchli"
                            2 => "I&#46; Luchsinger"
                            3 => "M&#46; Theiler"
                            4 => "L&#46; Weibel"
                            5 => "A&#46; Schwieger-Briel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/pde.13813"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "36"
                        "paginaInicial" => "548"
                        "paginaFinal" => "554"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30900306"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Non-involuting congenital hemangiomas &#40;NICH&#41; with postnatal atypical growth&#58; a case series"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46;L&#46; Cossio"
                            1 => "J&#46; Dubois"
                            2 => "C&#46;C&#46; McCuaig"
                            3 => "J&#46; Coulombe"
                            4 => "A&#46; Hatami"
                            5 => "D&#46; Marcoux"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/pde.13837"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pediatr Dermatol&#46;"
                        "fecha" => "2019"
                        "volumen" => "36"
                        "paginaInicial" => "466"
                        "paginaFinal" => "470"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31033005"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Somatic activating mutations in GNAQ and GNA11 are associated with congenital hemangioma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "U&#46;M&#46; Ayturk"
                            1 => "J&#46;A&#46; Couto"
                            2 => "S&#46; Hann"
                            3 => "J&#46;B&#46; Mulliken"
                            4 => "K&#46;L&#46; Williams"
                            5 => "A&#46;Y&#46; Huang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ajhg.2016.03.009"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Hum Genet&#46;"
                        "fecha" => "2016"
                        "volumen" => "98"
                        "paginaInicial" => "789"
                        "paginaFinal" => "795"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27058448"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002353/v1_202110091021/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "34945"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Resident&#39;s Forum"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000009/v1_202110091021/S1578219021002353/v1_202110091021/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002353?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 12 10 22
2024 Octubre 70 50 120
2024 Septiembre 66 24 90
2024 Agosto 78 55 133
2024 Julio 71 28 99
2024 Junio 79 36 115
2024 Mayo 62 29 91
2024 Abril 52 21 73
2024 Marzo 57 25 82
2024 Febrero 46 38 84
2024 Enero 53 37 90
2023 Diciembre 38 20 58
2023 Noviembre 65 27 92
2023 Octubre 61 30 91
2023 Septiembre 54 32 86
2023 Agosto 36 11 47
2023 Julio 49 29 78
2023 Junio 44 22 66
2023 Mayo 44 25 69
2023 Abril 26 15 41
2023 Marzo 46 23 69
2023 Febrero 39 23 62
2023 Enero 31 28 59
2022 Diciembre 47 49 96
2022 Noviembre 31 30 61
2022 Octubre 27 20 47
2022 Septiembre 26 37 63
2022 Agosto 25 35 60
2022 Julio 21 34 55
2022 Junio 21 25 46
2022 Mayo 50 55 105
2022 Abril 52 32 84
2022 Marzo 64 70 134
2022 Febrero 62 35 97
2022 Enero 46 38 84
2021 Diciembre 53 34 87
2021 Noviembre 46 53 99
2021 Octubre 84 78 162
2021 Septiembre 70 49 119
2021 Agosto 43 40 83
2021 Julio 9 0 9
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?