array:25 [
  "pii" => "S1578219021000305"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2021.01.025"
  "estado" => "S300"
  "fechaPublicacion" => "2021-04-01"
  "aid" => "2526"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2020"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Actas Dermosifiliogr. 2021;112:384-5"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0001731020304695"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2020.10.006"
      "estado" => "S300"
      "fechaPublicacion" => "2021-04-01"
      "aid" => "2526"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "cor"
      "cita" => "Actas Dermosifiliogr. 2021;112:384-5"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Cartas al Director</span>"
        "titulo" => "R&#233;plica a &#171;Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen&#187;"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "384"
            "paginaFinal" => "385"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Comment on &#171;Characteristics of Oral Lesions in Patients With Hansen Disease&#187;"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 854
                "Ancho" => 1074
                "Tamanyo" => 170352
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#41; Placa infiltrativa en la mucosa del velo palatino&#46; B&#41; Aspecto cl&#237;nico tras 2 semanas de tratamiento con multiterapia OMS &#40;rifampicina&#44; clofazimina&#44; dapsona&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "A&#46; Pulido P&#233;rez, L&#46;M&#46; Nieto-Benito, M&#46; Berg&#243;n-Send&#237;n, R&#46; Su&#225;rez-Fern&#225;ndez"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Pulido P&#233;rez"
              ]
              1 => array:2 [
                "nombre" => "L&#46;M&#46;"
                "apellidos" => "Nieto-Benito"
              ]
              2 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Berg&#243;n-Send&#237;n"
              ]
              3 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Su&#225;rez-Fern&#225;ndez"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219021000305"
          "doi" => "10.1016/j.adengl.2021.01.025"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000305?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304695?idApp=UINPBA000044"
      "url" => "/00017310/0000011200000004/v1_202104020731/S0001731020304695/v1_202104020731/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219021000469"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.01.027"
    "estado" => "S300"
    "fechaPublicacion" => "2021-04-01"
    "aid" => "2525"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Actas Dermosifiliogr. 2021;112:385-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Comment on &#34;Ectropion in Dermatologic Surgery&#58; Exploration and Reconstruction Techniques&#34;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "385"
          "paginaFinal" => "388"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "R&#233;plica a &#171;Ectropi&#243;n en cirug&#237;a dermatol&#243;gica&#58; exploraci&#243;n y t&#233;cnicas reconstructivas&#187;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 2294
              "Ancho" => 3175
              "Tamanyo" => 543935
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Algorithm for examination and treatment of eyelid ectropion&#46; It is important to perform a complete examination to determine which treatment is required&#59; this ensures that the best outcomes are attained and reduces relapses&#46; Abbreviations&#58; LCT&#44; lateral canthal tendon&#59; MCT&#44; medial canthal tendon&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Ortiz-P&#233;rez"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Ortiz-P&#233;rez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731020304683"
        "doi" => "10.1016/j.ad.2020.10.005"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304683?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000469?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000004/v1_202104020837/S1578219021000469/v1_202104020837/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S1578219020303772"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2020.12.010"
    "estado" => "S300"
    "fechaPublicacion" => "2021-04-01"
    "aid" => "2517"
    "copyright" => "AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2021;112:382-3"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Ewing&#39;s Primary Cutaneous Sarcoma in a Pregnant Patient&#58; A Case Report"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "382"
          "paginaFinal" => "383"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Sarcoma de Ewing Cut&#225;neo Primario en una Paciente Embarazada&#58; informe de un caso caso"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1205
              "Ancho" => 905
              "Tamanyo" => 144783
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">5-cm firm erythematous mass&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marielos Posada, Gabriela Villalta, Mar&#237;a-Sof&#237;a Rold&#225;n, Helga Sarti"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Marielos"
              "apellidos" => "Posada"
            ]
            1 => array:2 [
              "nombre" => "Gabriela"
              "apellidos" => "Villalta"
            ]
            2 => array:2 [
              "nombre" => "Mar&#237;a-Sof&#237;a"
              "apellidos" => "Rold&#225;n"
            ]
            3 => array:2 [
              "nombre" => "Helga"
              "apellidos" => "Sarti"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731020304403"
        "doi" => "10.1016/j.ad.2019.02.036"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304403?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219020303772?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000004/v1_202104020837/S1578219020303772/v1_202104020837/en/main.assets"
  ]
  "en" => array:16 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letters to the Editor</span>"
    "titulo" => "Comment on &#171;Characteristics of Oral Lesions in Patients With Hansen Disease&#187;"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#58;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "384"
        "paginaFinal" => "385"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "A&#46; Pulido P&#233;rez, L&#46;M&#46; Nieto-Benito, M&#46; Berg&#243;n-Send&#237;n, R&#46; Su&#225;rez-Fern&#225;ndez"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "A&#46;"
            "apellidos" => "Pulido P&#233;rez"
            "email" => array:1 [
              0 => "ana.pulido@salud.madrid.org"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "L&#46;M&#46;"
            "apellidos" => "Nieto-Benito"
          ]
          2 => array:2 [
            "nombre" => "M&#46;"
            "apellidos" => "Berg&#243;n-Send&#237;n"
          ]
          3 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Su&#225;rez-Fern&#225;ndez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital General Universitario Gregorio Mara&#241;&#243;n&#44; Madrid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "R&#233;plica a &#171;Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen&#187;"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1193
            "Ancho" => 1500
            "Tamanyo" => 281268
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Infiltrative plaque on the mucous membrane of the soft palate&#46; B&#44; Clinical appearance after 2 weeks of multidrug therapy with the World Health Organization recommended regimen &#40;rifampicin&#44; clofazimine&#44; dapsone&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with great interest the excellent article by Moronta Castellano et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> on oral manifestations of Hansen disease&#46; The authors report findings that are specific for the disease and those that occur independently&#46; Consistent with data published to date&#44; the authors confirm involvement of the palatine mucosa as the most common lesion&#46; The findings affecting the palate were plaques or lepromas&#44; which are histologically characterized by the presence of a dense lymphohistiocytic infiltrate with no granulomas in which Fite-Faraco and Ziehl Neelsen staining revealed mycobacteria&#46; In this series&#44; most patients were receiving multidrug treatment for Hansen disease at the time of the evaluation of the oral lesions&#46; An interesting aspect not addressed in the text is the progress of these findings during specific treatment of the multibacillary forms of the disease&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">In our experience&#44; based on imported cases&#44; we have observed how specific oral lesions from patients with multibacillary forms of the disease responded early after initiation of multidrug treatment&#46; The first patient was a 38-year-old man from Brazil who had been diagnosed with histoid leprosy based on clinical&#44; histopathologic&#44; and microbiological characteristics&#44; with a high bacillary load in samples obtained from the skin smear and the nasal mucosa&#46; The physical examination revealed multiple nodules and shiny plaques mainly on the face&#46; Of particular interest on the oral mucosa&#44; we observed a plaque affecting most of the soft palate and forming a central cleft &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; The patient was prescribed multidrug treatment according to the World Health Organization recommended regimen &#40;rifampicin&#44; clofazimine&#44; dapsone&#41;&#46; The first clinical check-up during the 2 subsequent weeks revealed a marked improvement in the oral lesions &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; The second case involved a 27-year-old woman from Brazil who had been diagnosed with lepromatous leprosy and erythema nodosum leprosum as the first manifestation of the disease&#46; In this case&#44; facial involvement was minimal or nonexistent&#44; with only small lepromas on the ear lobes&#46; A plaque similar to that in the first case was observed on the oral mucosa&#44; again on the soft palate&#44; although it was less thick and extensive&#46; After initiation of multidrug therapy with rifampicin&#44; clofazimine&#44; dapsone&#44; and prednisone&#44; involvement of the palatine mucosa resolved in 10 days&#44; with no further changes on the skin surface&#46; Furthermore&#44; in both patients&#44; we observed how this improvement in the oral lesions occurred in parallel to the favorable progress of nasal symptoms &#40;congestion&#44; rhinorrhea&#41;&#46; The latter observation could be explained by the fact that the oral lesions developed after extension of the bacillus from the nasal mucosa&#46;<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2&#44;3</span></a> Another aspect of interest in these patients is the presence of lesions on the oral mucosa secondary to poor oral-dental hygiene&#44; either as a consequence of a limitation secondary to the presence of deformities &#40;or mutilations in advanced cases&#41; or because of a loss of motivation for self-care&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">In summary&#44; while our observation is based on isolated cases&#44; we wondered whether the early response of the oral lesions could act as an additional tool for monitoring adherence to multidrug therapy&#46; Similarly&#44; this initial response in the oral mucosa could reinforce the patient&#8217;s perception of the benefits of treatment&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2020-07-30"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Pulido P&#233;rez A&#44; Nieto-Benito LM&#44; Berg&#243;n-Send&#237;n M&#44; Su&#225;rez-Fern&#225;ndez R&#46; R&#233;plica a &#171;Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen&#187;&#46; Actas Dermosifiliogr&#46; 2021&#59;112&#58;384&#8211;385&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1193
            "Ancho" => 1500
            "Tamanyo" => 281268
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Infiltrative plaque on the mucous membrane of the soft palate&#46; B&#44; Clinical appearance after 2 weeks of multidrug therapy with the World Health Organization recommended regimen &#40;rifampicin&#44; clofazimine&#44; dapsone&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:3 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Moronta Castellano"
                            1 => "M&#46; Villarroel-Dorrego"
                            2 => "L&#46; Crespo Lessmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2020.05.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2020"
                        "volumen" => "111"
                        "paginaInicial" => "671"
                        "paginaFinal" => "677"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32574720"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Oral manifestation in leprosy&#58; a cross-sectional study of 100 cases with literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46; Vohra"
                            1 => "M&#46;S&#46;U&#46; Rahman"
                            2 => "B&#46; Subhada"
                            3 => "R&#46;V&#46;C&#46; Tiwari"
                            4 => "M&#46;S&#46; Nabeel Althaf"
                            5 => "M&#46;J&#46; Gahlawat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/jfmpc.jfmpc_766_19"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Family Med Prim Care&#46;"
                        "fecha" => "2019"
                        "volumen" => "8"
                        "paginaInicial" => "3689"
                        "paginaFinal" => "3694"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31803674"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manifestaciones orales&#46; Manual actualizado de Leprolog&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; N&#250;&#241;ez Mart&#237;"
                            1 => "Sanatorio de Fontilles"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "fecha" => "2008"
                        "paginaInicial" => "103"
                        "paginaFinal" => "107"
                        "editorial" => "Ed&#46; Fontilles"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011200000004/v1_202104020837/S1578219021000305/v1_202104020837/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "89626"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letter to the Editors"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000004/v1_202104020837/S1578219021000305/v1_202104020837/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000305?idApp=UINPBA000044"
]
Compartir
Información de la revista

Estadísticas

Siga este enlace para acceder al texto completo del artículo

Letters to the Editor
Comment on «Characteristics of Oral Lesions in Patients With Hansen Disease»
Réplica a «Caracterización de lesiones bucales de pacientes con enfermedad de Hansen»
A. Pulido Pérez
Autor para correspondencia
ana.pulido@salud.madrid.org

Corresponding author.
, L.M. Nieto-Benito, M. Bergón-Sendín, R. Suárez-Fernández
Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Leído
3940
Veces
se ha leído el artículo
1567
Total PDF
2373
Total HTML
Compartir estadísticas
 array:25 [
  "pii" => "S1578219021000305"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2021.01.025"
  "estado" => "S300"
  "fechaPublicacion" => "2021-04-01"
  "aid" => "2526"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2020"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "cor"
  "cita" => "Actas Dermosifiliogr. 2021;112:384-5"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0001731020304695"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2020.10.006"
      "estado" => "S300"
      "fechaPublicacion" => "2021-04-01"
      "aid" => "2526"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "cor"
      "cita" => "Actas Dermosifiliogr. 2021;112:384-5"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Cartas al Director</span>"
        "titulo" => "R&#233;plica a &#171;Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen&#187;"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "384"
            "paginaFinal" => "385"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Comment on &#171;Characteristics of Oral Lesions in Patients With Hansen Disease&#187;"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 854
                "Ancho" => 1074
                "Tamanyo" => 170352
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#41; Placa infiltrativa en la mucosa del velo palatino&#46; B&#41; Aspecto cl&#237;nico tras 2 semanas de tratamiento con multiterapia OMS &#40;rifampicina&#44; clofazimina&#44; dapsona&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "A&#46; Pulido P&#233;rez, L&#46;M&#46; Nieto-Benito, M&#46; Berg&#243;n-Send&#237;n, R&#46; Su&#225;rez-Fern&#225;ndez"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Pulido P&#233;rez"
              ]
              1 => array:2 [
                "nombre" => "L&#46;M&#46;"
                "apellidos" => "Nieto-Benito"
              ]
              2 => array:2 [
                "nombre" => "M&#46;"
                "apellidos" => "Berg&#243;n-Send&#237;n"
              ]
              3 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Su&#225;rez-Fern&#225;ndez"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219021000305"
          "doi" => "10.1016/j.adengl.2021.01.025"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000305?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304695?idApp=UINPBA000044"
      "url" => "/00017310/0000011200000004/v1_202104020731/S0001731020304695/v1_202104020731/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219021000469"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.01.027"
    "estado" => "S300"
    "fechaPublicacion" => "2021-04-01"
    "aid" => "2525"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "cor"
    "cita" => "Actas Dermosifiliogr. 2021;112:385-8"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Comment on &#34;Ectropion in Dermatologic Surgery&#58; Exploration and Reconstruction Techniques&#34;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "385"
          "paginaFinal" => "388"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "R&#233;plica a &#171;Ectropi&#243;n en cirug&#237;a dermatol&#243;gica&#58; exploraci&#243;n y t&#233;cnicas reconstructivas&#187;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 2294
              "Ancho" => 3175
              "Tamanyo" => 543935
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Algorithm for examination and treatment of eyelid ectropion&#46; It is important to perform a complete examination to determine which treatment is required&#59; this ensures that the best outcomes are attained and reduces relapses&#46; Abbreviations&#58; LCT&#44; lateral canthal tendon&#59; MCT&#44; medial canthal tendon&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Ortiz-P&#233;rez"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Ortiz-P&#233;rez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731020304683"
        "doi" => "10.1016/j.ad.2020.10.005"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304683?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000469?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000004/v1_202104020837/S1578219021000469/v1_202104020837/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S1578219020303772"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2020.12.010"
    "estado" => "S300"
    "fechaPublicacion" => "2021-04-01"
    "aid" => "2517"
    "copyright" => "AEDV"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2021;112:382-3"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Ewing&#39;s Primary Cutaneous Sarcoma in a Pregnant Patient&#58; A Case Report"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "382"
          "paginaFinal" => "383"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Sarcoma de Ewing Cut&#225;neo Primario en una Paciente Embarazada&#58; informe de un caso caso"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1205
              "Ancho" => 905
              "Tamanyo" => 144783
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">5-cm firm erythematous mass&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marielos Posada, Gabriela Villalta, Mar&#237;a-Sof&#237;a Rold&#225;n, Helga Sarti"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Marielos"
              "apellidos" => "Posada"
            ]
            1 => array:2 [
              "nombre" => "Gabriela"
              "apellidos" => "Villalta"
            ]
            2 => array:2 [
              "nombre" => "Mar&#237;a-Sof&#237;a"
              "apellidos" => "Rold&#225;n"
            ]
            3 => array:2 [
              "nombre" => "Helga"
              "apellidos" => "Sarti"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731020304403"
        "doi" => "10.1016/j.ad.2019.02.036"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304403?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219020303772?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000004/v1_202104020837/S1578219020303772/v1_202104020837/en/main.assets"
  ]
  "en" => array:16 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letters to the Editor</span>"
    "titulo" => "Comment on &#171;Characteristics of Oral Lesions in Patients With Hansen Disease&#187;"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#58;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "384"
        "paginaFinal" => "385"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "A&#46; Pulido P&#233;rez, L&#46;M&#46; Nieto-Benito, M&#46; Berg&#243;n-Send&#237;n, R&#46; Su&#225;rez-Fern&#225;ndez"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "A&#46;"
            "apellidos" => "Pulido P&#233;rez"
            "email" => array:1 [
              0 => "ana.pulido@salud.madrid.org"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "L&#46;M&#46;"
            "apellidos" => "Nieto-Benito"
          ]
          2 => array:2 [
            "nombre" => "M&#46;"
            "apellidos" => "Berg&#243;n-Send&#237;n"
          ]
          3 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Su&#225;rez-Fern&#225;ndez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital General Universitario Gregorio Mara&#241;&#243;n&#44; Madrid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "R&#233;plica a &#171;Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen&#187;"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1193
            "Ancho" => 1500
            "Tamanyo" => 281268
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Infiltrative plaque on the mucous membrane of the soft palate&#46; B&#44; Clinical appearance after 2 weeks of multidrug therapy with the World Health Organization recommended regimen &#40;rifampicin&#44; clofazimine&#44; dapsone&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with great interest the excellent article by Moronta Castellano et al&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> on oral manifestations of Hansen disease&#46; The authors report findings that are specific for the disease and those that occur independently&#46; Consistent with data published to date&#44; the authors confirm involvement of the palatine mucosa as the most common lesion&#46; The findings affecting the palate were plaques or lepromas&#44; which are histologically characterized by the presence of a dense lymphohistiocytic infiltrate with no granulomas in which Fite-Faraco and Ziehl Neelsen staining revealed mycobacteria&#46; In this series&#44; most patients were receiving multidrug treatment for Hansen disease at the time of the evaluation of the oral lesions&#46; An interesting aspect not addressed in the text is the progress of these findings during specific treatment of the multibacillary forms of the disease&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">In our experience&#44; based on imported cases&#44; we have observed how specific oral lesions from patients with multibacillary forms of the disease responded early after initiation of multidrug treatment&#46; The first patient was a 38-year-old man from Brazil who had been diagnosed with histoid leprosy based on clinical&#44; histopathologic&#44; and microbiological characteristics&#44; with a high bacillary load in samples obtained from the skin smear and the nasal mucosa&#46; The physical examination revealed multiple nodules and shiny plaques mainly on the face&#46; Of particular interest on the oral mucosa&#44; we observed a plaque affecting most of the soft palate and forming a central cleft &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; The patient was prescribed multidrug treatment according to the World Health Organization recommended regimen &#40;rifampicin&#44; clofazimine&#44; dapsone&#41;&#46; The first clinical check-up during the 2 subsequent weeks revealed a marked improvement in the oral lesions &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; The second case involved a 27-year-old woman from Brazil who had been diagnosed with lepromatous leprosy and erythema nodosum leprosum as the first manifestation of the disease&#46; In this case&#44; facial involvement was minimal or nonexistent&#44; with only small lepromas on the ear lobes&#46; A plaque similar to that in the first case was observed on the oral mucosa&#44; again on the soft palate&#44; although it was less thick and extensive&#46; After initiation of multidrug therapy with rifampicin&#44; clofazimine&#44; dapsone&#44; and prednisone&#44; involvement of the palatine mucosa resolved in 10 days&#44; with no further changes on the skin surface&#46; Furthermore&#44; in both patients&#44; we observed how this improvement in the oral lesions occurred in parallel to the favorable progress of nasal symptoms &#40;congestion&#44; rhinorrhea&#41;&#46; The latter observation could be explained by the fact that the oral lesions developed after extension of the bacillus from the nasal mucosa&#46;<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2&#44;3</span></a> Another aspect of interest in these patients is the presence of lesions on the oral mucosa secondary to poor oral-dental hygiene&#44; either as a consequence of a limitation secondary to the presence of deformities &#40;or mutilations in advanced cases&#41; or because of a loss of motivation for self-care&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">In summary&#44; while our observation is based on isolated cases&#44; we wondered whether the early response of the oral lesions could act as an additional tool for monitoring adherence to multidrug therapy&#46; Similarly&#44; this initial response in the oral mucosa could reinforce the patient&#8217;s perception of the benefits of treatment&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2020-07-30"
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Pulido P&#233;rez A&#44; Nieto-Benito LM&#44; Berg&#243;n-Send&#237;n M&#44; Su&#225;rez-Fern&#225;ndez R&#46; R&#233;plica a &#171;Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen&#187;&#46; Actas Dermosifiliogr&#46; 2021&#59;112&#58;384&#8211;385&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1193
            "Ancho" => 1500
            "Tamanyo" => 281268
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Infiltrative plaque on the mucous membrane of the soft palate&#46; B&#44; Clinical appearance after 2 weeks of multidrug therapy with the World Health Organization recommended regimen &#40;rifampicin&#44; clofazimine&#44; dapsone&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:3 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Caracterizaci&#243;n de lesiones bucales de pacientes con enfermedad de Hansen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46; Moronta Castellano"
                            1 => "M&#46; Villarroel-Dorrego"
                            2 => "L&#46; Crespo Lessmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2020.05.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr&#46;"
                        "fecha" => "2020"
                        "volumen" => "111"
                        "paginaInicial" => "671"
                        "paginaFinal" => "677"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/32574720"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Oral manifestation in leprosy&#58; a cross-sectional study of 100 cases with literature review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46; Vohra"
                            1 => "M&#46;S&#46;U&#46; Rahman"
                            2 => "B&#46; Subhada"
                            3 => "R&#46;V&#46;C&#46; Tiwari"
                            4 => "M&#46;S&#46; Nabeel Althaf"
                            5 => "M&#46;J&#46; Gahlawat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/jfmpc.jfmpc_766_19"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Family Med Prim Care&#46;"
                        "fecha" => "2019"
                        "volumen" => "8"
                        "paginaInicial" => "3689"
                        "paginaFinal" => "3694"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31803674"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manifestaciones orales&#46; Manual actualizado de Leprolog&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46;M&#46; N&#250;&#241;ez Mart&#237;"
                            1 => "Sanatorio de Fontilles"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "fecha" => "2008"
                        "paginaInicial" => "103"
                        "paginaFinal" => "107"
                        "editorial" => "Ed&#46; Fontilles"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011200000004/v1_202104020837/S1578219021000305/v1_202104020837/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "89626"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letter to the Editors"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000004/v1_202104020837/S1578219021000305/v1_202104020837/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000305?idApp=UINPBA000044"
]
Información del artículo
ISSN: 15782190
Idioma original: Inglés
Datos actualizados diariamente
año/Mes Html Pdf Total
2024 Noviembre 8 10 18
2024 Octubre 72 43 115
2024 Septiembre 64 28 92
2024 Agosto 87 74 161
2024 Julio 63 25 88
2024 Junio 60 30 90
2024 Mayo 61 24 85
2024 Abril 62 25 87
2024 Marzo 62 29 91
2024 Febrero 44 41 85
2024 Enero 45 29 74
2023 Diciembre 39 13 52
2023 Noviembre 75 28 103
2023 Octubre 51 22 73
2023 Septiembre 36 29 65
2023 Agosto 36 12 48
2023 Julio 43 45 88
2023 Junio 36 25 61
2023 Mayo 42 22 64
2023 Abril 31 19 50
2023 Marzo 62 23 85
2023 Febrero 47 17 64
2023 Enero 54 19 73
2022 Diciembre 39 28 67
2022 Noviembre 24 27 51
2022 Octubre 34 17 51
2022 Septiembre 38 36 74
2022 Agosto 36 42 78
2022 Julio 90 33 123
2022 Junio 30 34 64
2022 Mayo 58 37 95
2022 Abril 63 30 93
2022 Marzo 48 48 96
2022 Febrero 54 39 93
2022 Enero 83 37 120
2021 Diciembre 30 40 70
2021 Noviembre 61 37 98
2021 Octubre 46 64 110
2021 Septiembre 42 36 78
2021 Agosto 41 38 79
2021 Julio 46 49 95
2021 Junio 48 26 74
2021 Mayo 43 69 112
2021 Abril 91 109 200
2021 Marzo 53 31 84
2021 Febrero 90 28 118
2021 Enero 5 0 5
Mostrar todo

Siga este enlace para acceder al texto completo del artículo

Idiomas
Actas Dermo-Sifiliográficas
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?